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List of works by André Veillette

17 beta-estradiol regulates and v-Ha-ras transfection constitutively enhances MCF7 breast cancer cell interactions with basement membrane

scientific article

A function for the lck proto-oncogene

scientific article published on October 1989

A functional polymorphism of Ptpn22 is associated with type 1 diabetes in the BioBreeding rat

scientific journal article

A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.

scientific article published on 15 February 2016

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network

scientific article published on 17 July 2020

Activation by SLAM Family Receptors Contributes to NK Cell Mediated "Missing-Self" Recognition

scientific article

Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.

scientific article published on March 2005

Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation ⬇️

scientific article published on October 1, 1990

Activation of pp60c-src protein kinase activity in human colon carcinoma

scientific article

Adaptors in immune regulation

scientific article published on 01 December 2004

Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells

scientific article published on 01 January 1989

Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes

scientific article published on October 1989

Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation

scientific article published on October 1988

Analysis of pp60c-src in human colon carcinoma and normal human colon mucosal cells.

scientific article published in July 1987

Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor

scientific journal article

Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines

scientific journal article

Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

scientific article published on July 23, 1992

Avian CD4 and CD8 interact with a cellular tyrosine protein kinase homologous to mammalian p56lck

scientific article published on 01 February 1991

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

scientific article

CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells

scientific article published on 01 October 2020

CD4 and p56lck can stably associate when co-expressed in NIH3T3 cells

scientific article published on 01 September 1989

CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma

scientific article published on 02 June 2013

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

scientific article published on October 2013

Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma.

scientific article published on 15 May 2018

Comparison of p56lck and p59fyn protein expression in thymocyte subsets, peripheral T cells, NK cells, and lymphoid cell lines ⬇️

scientific article published on November 1, 1995

Consequence of the SLAM-SAP signaling pathway in innate-like and conventional lymphocytes

scientific article

Conserved cysteine residues are critical for the enzymatic function of the lymphocyte-specific tyrosine protein kinase p56lck

scientific article published on 01 August 1993

Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity

scientific article

Control of dendritic cell migration, T cell-dependent immunity, and autoimmunity by protein tyrosine phosphatase PTPN12 expressed in dendritic cells

scientific article published on 23 December 2013

Coordinate alteration of pp60c-src abundance and c-src RNA expression in human neuroblastoma variants.

scientific article

Correction: Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.

scientific article published on 12 September 2016

Critical Role for SLAM/SAP Signaling in the Thymic Developmental Programming of IL-17- and IFN-γ-Producing γδ T Cells

scientific article published on 05 February 2020

Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation

scientific article published on 01 January 2020

Critical Role of SAP in Progression and Reactivation but Not Maintenance of T Cell-Dependent Humoral Immunity ⬇️

scientific article published on January 14, 2013

Csk

DNAM-1 controls NK cell activation via an ITT-like motif

scientific article published on 9 November 2015

De novo-developed T cells have compromised response to existing alloantigens: using Ld-specific transgenic 2C T cells as tracers in a mouse heart transplantation model ⬇️

scientific article published on July 1, 1998

Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.

scientific article published on 29 August 2016

Developing combination immunotherapies against cancer that make sense

scientific article published on 01 November 2018

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn ⬇️

scientific article published on June 1, 1992

Differential requirement for the SAP-Fyn interaction during NK T cell development and function

scientific article

Do NK cells always need a license to kill?

scientific article published on April 2010

EAT-2 : un nouveau régulateur de la fonction des cellules NK

EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization.

scientific article published on 31 March 2014

Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

scientific article

Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

scientific article published in Nature

Enrichment of lck in lipid rafts regulates colocalized fyn activation and the initiation of proximal signals through TCR alpha beta

scientific article published on April 2004

Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells

scientific journal article

Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines

scientific article published in September 1987

Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation.

scientific article published in November 2004

Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.

scientific article

How do SAP family deficiencies compromise immunity?

scientific article published on 23 July 2010

Immune cell inhibition by SLAMF7 is mediated by a mechanism requiring src kinases, CD45, and SHIP-1 that is defective in multiple myeloma cells

scientific article published on 13 October 2014

Immune functions in mice lacking Clnk, an SLP-76-related adaptor expressed in a subset of immune cells

scientific article published on July 2004

Immune regulation by SLAM family receptors and SAP-related adaptors

scientific article

Immunology: Csk keeps LYP on a leash.

scientific article

Immunology: Magnesium in a signalling role

scientific article published on 27 July 2011

Immunology: When lymphocytes run out of steam

scientific article

Impaired signaling in alloantigen-specific CD8+ T cells tolerized in vivo: employing a model of Ld-specific TCR transgenic mice transplanted with allogenic hearts under the cover of a short-term rapamycin treatment

scientific article published on 01 November 1996

Importance and mechanism of 'switch' function of SAP family adapters.

scientific article

Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

scientific article published in November 1989

Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function

scientific journal article

Inhibition of the Jun N-terminal protein kinase pathway by SHIP-1, a lipid phosphatase that interacts with the adaptor molecule Dok-3

scientific article

Inhibitory Tyrosine Protein Kinase p50 Is Associated with Protein-tyrosine Phosphatase PTP-PEST in Hemopoietic and Non-hemopoietic Cells ⬇️

scientific article published on September 12, 1997

Interactions of the SH2 domain of lymphocyte-specific tyrosine protein kinase p56lck with phosphotyrosine-containing proteins

scientific article published on 01 October 1993

Interleukin 2–mediated Uncoupling of T Cell Receptor α/β from CD3 Signaling ⬇️

scientific article published on November 2, 1998

Intramolecular and extramolecular mechanisms repress the catalytic function of p56lck in resting T-lymphocytes

scientific article

Introduction: Signaling and signal diversification in antigen-specific immune cells

scientific article published on 01 September 2019

It takes a village

scientific article published on 01 October 2018

Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts

scientific article

Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition

scientific article

Loss of human ICOSL results in combined immunodeficiency

scientific article published on 01 December 2018

Lymphocyte activation

Macrophage Fusion Is Controlled by the Cytoplasmic Protein Tyrosine Phosphatase PTP-PEST/PTPN12 ⬇️

scientific article published on April 15, 2013

Molecular and immunological basis of X-linked lymphoproliferative disease

scientific article

Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors

scientific article

Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency.

scientific article published on 16 February 2017

Mosaic partial deletion of PTPN12 in a child with interrupted aortic arch type A

scientific article published on 06 August 2015

NK cell regulation by SLAM family receptors and SAP-related adapters

scientific article published on December 2006

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

scientific article published on September 1993

Negative regulation of immunoreceptor signaling

scientific article

Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor

scientific journal article

Ntk: a Csk-related protein-tyrosine kinase expressed in brain and T lymphocytes

scientific article

Oncogenic activation of p59fyn tyrosine protein kinase by mutation of its carboxyl-terminal site of tyrosine phosphorylation, tyrosine 528.

scientific article published on April 1994

Organization of immunoreceptor signaling by adapters

scientific article published on 01 November 2009

PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes

scientific article published on 8 January 2007

PEST family phosphatases in immunity, autoimmunity, and autoinflammatory disorders

scientific article published on March 2009

Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor

scientific journal article

Pillars article: the CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. 1994 ⬇️

scientific article published on September 1, 2010

Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.

scientific article published in May 1988

Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency.

scientific article

Profound block in thymocyte development in mice lacking p56lck

scientific article

Progression of AITL-like tumors in mice is driven by Tfh signature proteins and T-B cross talk

scientific article published on 01 March 2020

Protein tyrosine phosphatase alpha regulates Fyn activity and Cbp/PAG phosphorylation in thymocyte lipid rafts

scientific article

Protein tyrosine phosphatases in lymphocyte activation and autoimmunity ⬇️

scientific article published on April 18, 2012

Proximal protein tyrosine kinases in immunoreceptor signaling

scientific article

Reconstitution of interactions between protein-tyrosine phosphatase CD45 and tyrosine-protein kinase p56(lck) in nonlymphoid cells

scientific article published on May 1997

Redefining interferon-producing killer dendritic cells as a novel intermediate in NK-cell differentiation

scientific article published on 21 February 2012

Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts ⬇️

scientific article published on May 5, 2003

Regulation of Zap-70 by Src family tyrosine protein kinases in an antigen-specific T-cell line

scientific article published on February 1995

Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn.

scientific article

Regulation of the enzymatic function of the lymphocyte-specific tyrosine protein kinase p56lck by the non-catalytic SH2 and SH3 domains

scientific article published on May 1, 1992

SAP expression in T cells, not in B cells, is required for humoral immunity

scholarly article

SAP: a molecular switch regulating the immune response through a unique signaling mechanism

scientific article

SIRPα-CD47 Immune Checkpoint Blockade in Anticancer Therapy

scientific article published on 11 January 2018

SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors

scientific article published on May 2004

SLAM family receptors and SAP-related adaptors: matters arising

scientific article published on 3 April 2006

SLAM family receptors control pro-survival effectors in germinal center B cells to promote humoral immunity

scientific article published on 01 March 2021

SLAM family receptors in normal immunity and immune pathologies

scientific article published on 02 December 2015

SLAM receptors foster iNKT cell development by reducing TCR signal strength after positive selection

scientific article published on 04 March 2019

SLAM-associated protein favors the development of iNKT2 over iNKT17 cells

scientific article published on 24 June 2016

SLAM-family receptors: immune regulators with or without SAP-family adaptors

scientific article

SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint

scientific article published on 03 March 2020

SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.

scientific article published on 19 April 2017

Signaling Regulatory Protein (SIRP)α-CD47 Blockade Joins the Ranks of Immune Checkpoint Inhibition

scientific article published on 27 February 2019

Specialised adaptors in immune cells

scientific article published on April 2004

Src-related protein tyrosine kinases and T-cell receptor signalling

scientific article published on February 1, 1992

Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck ⬇️

scientific article published on June 1, 1992

Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.

scientific article

T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

scientific article

TCR alpha beta-independent CD28 signaling and costimulation require non-CD4-associated Lck.

scientific article published on August 1999

The Adaptor SAP Controls NK Cell Activation by Regulating the Enzymes Vav-1 and SHIP-1 and by Enhancing Conjugates with Target Cells ⬇️

scientific article published on June 7, 2012

The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation

scientific article published on October 1990

The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors

scientific article

The Lymphocyte-Specific Tyrosine Protein Kinase p56lck ⬇️

scientific article published on January 1, 1991

The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2 ⬇️

scientific article published on August 27, 2010

The SAP family of adaptors in immune regulation

scientific article

The SAP family: a new class of adaptor-like molecules that regulates immune cell functions

scientific article published on 19 February 2002

The SH2 domain is required for stable phosphorylation of p56lck at tyrosine 505, the negative regulatory site

scientific article

The SLAM family of immune-cell receptors

scientific article (publication date: June 2003)

The Src and Csk families of tyrosine protein kinases in hemopoietic cells.

scientific article published on August 1995

The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation

scientific article published on 21 February 2013

The adaptor molecule signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is essential in mechanisms involving the Fyn tyrosine kinase for induction and progression of collagen-induced arthritis

scientific article published on 17 September 2013

The cytoplasmic domain of CD4 is required for stable association with the lymphocyte-specific tyrosine protein kinase p56lck

scientific article published on June 1990

The lymphocyte-specific tyrosine protein kinase p56lck

scientific article published on May 1991

The phosphatase PTP-PEST/PTPN12 regulates endothelial cell migration and adhesion, but not permeability, and controls vascular development and embryonic viability

scientific article

The unique amino-terminal domain of p56lck regulates interactions with tyrosine protein phosphatases in T lymphocytes

scientific article

Two distinct protein isoforms are encoded by ntk, a csk-related tyrosine protein kinase gene.

scientific article published on December 1994

Two novel mutations in ZAP70 gene that result in human immunodeficiency

scientific article published on 11 September 2017

Tyrosine phosphorylation of GAP and GAP-associated proteins in lymphoid and fibroblast cells expressing lck.

scientific article published on June 1991

Tyrosine protein kinases in T lymphocytes

scientific article published on 01 January 1994

Unique catalytic properties dictate the enhanced function of p59fynT, the hemopoietic cell-specific isoform of the Fyn tyrosine protein kinase, in T cells

scientific article published on July 1994

X-linked lymphoproliferative syndromes and related autosomal recessive disorders.

scientific article published on December 2013

[Loss of human ICOSLG results in combined immunodeficiency]

scientific article published on 01 August 2019

src-related protein tyrosine kinases

scientific article published on January 1989

tkl is the avian homolog of the mammalian lck tyrosine protein kinase gene

scientific article published on March 1992

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