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List of works by Christine Mummery

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes

scientific article published on 17 November 2017

A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells

scientific article published on February 2004

A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness

scientific article published on 20 March 2020

A case for crowd sourcing in stem cell research

scientific article

A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors

scientific article published on 19 January 2016

A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells

scientific article published on 28 July 2016

A practical guide for the identification of membrane and plasma membrane proteins in human embryonic stem cells and human embryonal carcinoma cells

scientific article published on October 2008

A promoter-level mammalian expression atlas

scientific article

A quest for human and mouse embryonic stem cell-specific proteins.

scientific article published on 6 April 2006

A short-term screening test for teratogens using differentiating neuroblastoma cells in vitro

scientific article published on 01 April 1984

Activation of both transforming growth factor-β and bone morphogenetic protein signalling pathways upon traumatic brain injury restrains pro-inflammatory and boosts tissue reparatory responses of reactive astrocytes and microglia

scientific article published on 21 October 2019

Activation of the canonical bone morphogenetic protein (BMP) pathway during lung morphogenesis and adult lung tissue repair

scientific article (publication date: 2012)

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

scientific article

Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells.

scientific article

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

scientific article published on 23 June 2018

Advantages of the avian model for human ovarian cancer

scientific article

Aggregation and cell cycle dependent retinoic acid receptor mRNA expression in P19 embryonal carcinoma cells

scientific article published on February 1, 1992

Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure

scientific article published on 8 October 2015

Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5

scientific journal article

An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics

scientific article published on 01 September 2007

Assessment of functional competence of endothelial cells from human pluripotent stem cells in zebrafish embryos

scientific article published on 01 January 2014

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.

scientific article published on 19 February 2015

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

scientific article published on July 2006

BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo

scientific article published on 17 February 2016

BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo

scientific journal article

BMP signalling differentially regulates distinct haematopoietic stem cell types

scientific article

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells

scientific article

BMP4 promotes EMT and mesodermal commitment in human embryonic stem cells via SLUG and MSX2.

scientific article published on March 2014

Blinded, multi-centre evaluation of drug-induced changes in contractility using human induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 18 May 2020

Bone morphogenetic proteins and retinoic acid induce human endogenous retrovirus HERV-K expression in NT2D1 human embryonal carcinoma cells

scientific article published in August 2000

Building blocks for a European Organ-on-Chip roadmap

scientific article published on 01 January 2019

CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy.

scientific article

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function

scientific journal article

Cadmium-induced inhibition of proliferation and differentiation of embryonal carcinoma cells and mechanistic aspects of protection by zinc

scientific article published in October 1993

Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models

scientific article

Cardiology: solace for the broken-hearted?

scientific article published on 01 February 2005

Cardiomyocyte differentiation from embryonic and adult stem cells

scientific article

Cardiomyocyte differentiation of mouse and human embryonic stem cells

scientific article

Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models

scientific article published on February 2011

Cardiomyocyte reprogramming and the new age of cellular alchemy

scientific article published on 26 June 2012

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease

scientific article published on 30 May 2012

Cardiomyocytes derived from stem cells

scientific article

Cardiomyocytes from human and mouse embryonic stem cells.

scientific article published on January 2007

Cardiomyocytes from human embryonic stem cells: more than heart repair alone

scientific article published on June 2007

Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery

scientific article published on 15 September 2009

Cation transport and growth regulation in neuroblastoma cells. Modulations of K+ transport and electrical membrane properties during the cell cycle

scientific article published in April 1981

Celebrating 10 years of hESC lines: an interview with Christine Mummery. Interviewed by Miodrag Stojković and Susan Daher

scientific article published in January 2009

Cell cycle analysis during retinoic acid induced differentiation of a human embryonal carcinoma-derived cell line

scientific article published on 01 March 1987

Cell replacement therapies: is it time to reprogram?

scientific article

Challenges in using stem cells for cardiac repair

scientific article published on April 2010

Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines.

scientific article published in June 1990

Characterization of 42K+ and 86Rb+ transport and electrical membrane properties in exponentially growing neuroblastoma cells

scientific article published in April 1981

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

scientific article

Characterization of polyclonal anti-peptide antibodies specific for transforming growth factor beta 2.

scientific article published in October 1990

Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells

scientific article

Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation

scientific article published on 31 October 2019

Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three-Dimensional Model of Cardiac Microtissue

scientific article published on 18 October 2017

Commitment to differentiation induced by retinoic acid in P19 embryonal carcinoma cells is cell cycle dependent

scientific article published in May 1987

Comparative analysis of 82 expressed sequence tags from a cattle ovary cDNA library ⬇️

scientific article published on July 1, 1998

Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice

scientific article published on 20 November 2007

Complex Tissue and Disease Modeling using hiPSCs

scientific article published on March 2016

Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development

scientific article published on December 2002

Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease

scientific article published on 2 June 2016

Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction

scientific article published on November 2004

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function

scientific article published on 13 October 2015

Conversion of mature human β-cells into glucagon-producing α-cells.

scientific article published on 8 April 2013

Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties

scientific article published on 07 January 2020

Current controversies in prenatal diagnosis 1: is stem cell therapy ready for human fetuses?

scientific article published on 03 January 2011

Cytoskeletal heart-enriched actin-associated protein (CHAP) is expressed in striated and smooth muscle cells in chick and mouse during embryonic and adult stages

scientific article published on 01 January 2011

Cytostretch, an Organ-on-Chip Platform

scientific article published on 14 July 2016

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.

scientific article published on 13 October 2017

Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2

scientific article published on 01 December 2018

Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia

scientific article

Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development

scientific article published in December 1992

Differential localization of TGF-beta 2 in mouse preimplantation and early postimplantation development

scientific article published in June 1991

Differentially regulated production of platelet-derived growth factor and of transforming growth factor beta by a human teratocarcinoma cell line

scientific article published in September 1988

Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives.

scientific article published in June 2019

Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells

scientific article published on 17 September 2007

Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions

scientific article

Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

scientific article

Differentiation of human embryonic stem cells to cardiomyocytes by coculture with endoderm in serum-free medium

scientific article published on July 2007

Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells

scientific article published on 12 May 2003

Differentiation-Defective Human Induced Pluripotent Stem Cells Reveal Strengths and Limitations of the Teratoma Assay and In Vitro Pluripotency Assays

scientific article

Direct cardiomyocyte reprogramming: a new direction for cardiovascular regenerative medicine

scientific article

Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys

scientific article published on 7 March 2011

Distribution of phosphorylated Smad2 identifies target tissues of TGF beta ligands in mouse development

scientific article

Dual reporter MESP1 mCherry/w-NKX2-5 eGFP/w hESCs enable studying early human cardiac differentiation

scientific article published in January 2015

ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis

scientific article published on 28 January 2014

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs)

scientific article published on 12 May 2017

Embryonic stem cell proteomics

scientific article published on August 2006

Endoglin has a crucial role in blood cell-mediated vascular repair

scientific article published on 6 November 2006

Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts

scientific article

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

scientific article published on 23 September 2004

Endoglin-mediated vascular remodeling: mechanisms underlying hereditary hemorrhagic telangiectasia

scientific article published on January 2008

Engineered models of the human heart: directions and challenges

scientific article published on 03 December 2020

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK.

scientific article published on 15 November 2007

Epidermal growth factor receptor expression during morphological differentiation of pheochromocytoma cells, induced by nerve growth factor or dibutyryl cyclic AMP

scientific article published on 01 June 1987

Epidermal growth factor-receptor interaction in rat pheochromocytoma (PC12) and human epidermoid A431 cells: biochemical and ultrastructural studies

scientific article published on 01 April 1984

Erratum: Corrigendum: BMP signalling differentially regulates distinct haematopoietic stem cell types

scientific article published in Nature Communications

Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors

scientific article published on 01 July 1986

Ethics. The ISSCR guidelines for human embryonic stem cell research

scientific article published on February 2007

Executive summary of the 12th HHT international scientific conference.

scientific article published on 16 November 2017

Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction

scientific article published on 01 March 2020

Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells.

scientific article

Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development

scientific article published in August 1997

Expression of TGF-beta s and their receptors during implantation and organogenesis of the mouse embryo

scientific article published in December 1994

Expression of growth factors during the differentiation of embryonic stem cells in monolayer

scientific article published in December 1990

Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis

article

Expression of the α6A integrin splice variant in developing mouse embryonic stem cell aggregates and correlation with cardiac muscle differentiation

Expression of transforming growth factor beta 2 during the differentiation of murine embryonal carcinoma and embryonic stem cells.

scientific article published on January 1990

Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis

scientific journal article

Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development

scientific article published on 01 November 1995

Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes

scientific article

FANTOM5 CAGE profiles of human and mouse samples

scientific article published on 29 August 2017

Feeder-Free Monolayer Cultures of Human Embryonic Stem Cells Express an Epithelial Plasma Membrane Protein Profile

article

Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification

scientific article published in January 2008

Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes

scientific article published on 22 May 2020

Follow-up of Thalidomide treatment in patients with Hereditary Haemorrhagic Telangiectasia.

scientific article published in December 2015

From stealing fire to cellular reprogramming: a scientific history leading to the 2012 Nobel Prize

scientific article

Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro--correlation between contraction force and electrophysiology

scientific article published on 18 February 2015

Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts

scientific article published on 24 October 2013

Functions of the TGFbeta superfamily in human embryonic stem cells

scientific article

G1-phase regulators,cyclin D1, cyclin D2, andcyclin D3: Up-regulation at gastrulation and dynamic expression during neurulation ⬇️

scientific article published on May 1, 1998

Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines

scientific article

Generation and Functional Characterization of Monocytes and Macrophages Derived from Human Induced Pluripotent Stem Cells

scientific article published on 01 March 2020

Generation and genetic repair of 2 iPSC clones from a patient bearing a heterozygous c.1120del18 mutation in the ACVRL1 gene leading to Hereditary Hemorrhagic Telangiectasia (HHT) type 2

scientific article published on 28 May 2020

Generation of a floxed allele of the mouse Endoglin gene

scientific article

Generation of induced pluripotent stem cells from human foetal fibroblasts using the Sleeping Beauty transposon gene delivery system.

scientific article

Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene

scientific article published on 08 April 2020

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

scientific article published on 29 May 2014

Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells

scientific article published on March 26, 2021

Genetic manipulation of human embryonic stem cells in serum and feeder-free media

scientific article

Genetic selection of cardiomyocytes from human embryonic stem cells

scientific article published on 01 November 2007

Genetically Engineered Mesenchymal Stem Cells Influence Gene Expression in Donor Cardiomyocytes and the Recipient Heart ⬇️

scientific article published on June 7, 2012

Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes

scientific article published on 4 May 2006

Getting to the heart of the matter: direct reprogramming to cardiomyocytes

scientific article

Heart repair and stem cells

scientific article published on 28 September 2006

Her heart yearned for Boston: a few questions for Christine Mummery

scientific article published on February 2008

Hereditary hemorrhagic telangiectasia: an update on transforming growth factor beta signaling in vasculogenesis and angiogenesis

scientific article

Human Organs-on-Chips for Virology

scientific article published on 13 July 2020

Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells

scientific article published on 17 November 2017

Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium

scientific article published on 09 May 2009

Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts

scientific article

Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents

scientific article published on 24 April 2008

Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction

scientific article published on 17 August 2007

Human embryonic stem cells: genetic manipulation on the way to cardiac cell therapies

scientific article

Human embryonic stem cells: research, ethics and policy

scientific article

Human embryonic stem cells: towards therapies for cardiac disease. Derivation of a Dutch human embryonic stem cell line

scientific article published on October 2005

Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes.

scientific article published on June 2017

Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies

scientific article published on September 2017

Human stem cell models for predictive cardiac safety pharmacology

scientific article published on 01 May 2010

Human stem cells as a model for cardiac differentiation and disease.

scientific article published on March 2009

Human stem cells shape the future of cardiac regeneration research

scientific article published in June 2004

Human teratocarcinoma cells express functional insulin-like growth factor I receptors.

scientific article published in October 1989

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

scientific article published on 20 May 2020

Identification and characterization of polypeptide growth factors secreted by murine embryonal carcinoma cells

scientific article published in May 1989

Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-derived cardiomyocytes

scientific article published in March 2010

Identification of novel regulators associated with early-phase osteoblast differentiation

scientific article

Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

scientific article published on 25 February 2015

Impaired recruitment of HHT-1 mononuclear cells to the ischaemic heart is due to an altered CXCR4/CD26 balance

scientific article published on 17 September 2009

Implantation and Placentation

Improved genetic manipulation of human embryonic stem cells

scientific article

Improvement of mouse cardiac function by hESC-derived cardiomyocytes correlates with vascularity but not graft size

scientific article

In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells

scientific article published on 26 March 2020

Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures

scientific article

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva

scientific article published on 25 November 2015

Induced Pluripotent Stem Cells — A Cautionary Note ⬇️

scientific article published on 01 June 2011

Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

scientific article

Induced pluripotent stem cells: the new patient?

scientific article

Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A

scientific article

Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.

scientific article published on 12 April 2018

Inherited cardiac diseases, pluripotent stem cells, and genome editing combined-the past, present, and future

scientific article published on 16 December 2019

Inherited heart disease - what can we expect from the second decade of human iPS cell research?

scientific article

Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation

scientific article

Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells

scientific article published on 20 December 2007

Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?

scientific article published on 19 September 2016

Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations.

scientific article published on 28 January 2016

International coordination of large-scale human induced pluripotent stem cell initiatives: Wellcome Trust and ISSCR workshops white paper

scientific article published on December 2014

Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes.

scientific article published on 30 January 2017

Is heart regeneration on the right track?

scientific article

Isl1Cre reveals a common Bmp pathway in heart and limb development

scientific article

Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias

scientific article published on 01 November 2020

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

scientific article

Isolation and characterization of permanent cell lines from inner cell mass cells of bovine blastocysts.

scientific article published on April 1995

KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas

scientific article published on 28 May 2015

Knock-in of integrin beta 1D affects primary but not secondary myogenesis in mice

scientific article published on April 2003

Loss of EGF binding and cation transport response during differentiation of mouse neuroblastoma cells

scientific article published on 01 January 1983

Lymphangiogenesis and angiogenesis during human fetal pancreas development

scientific article published on November 2014

Lymphoblast-derived hiPS cell lines generated from four individuals of a family of genetically unrelated parents and their female monozygotic twins

scientific article published on 08 November 2019

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.

scientific article published on 27 December 2017

Membrane regulation of the Na+,K+-ATPase during the neuroblastoma cell cycle: correlation with protein lateral mobility

scientific article published on 01 January 1983

Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts

scientific article published on 7 April 2005

Microfluidic Assay for the Assessment of Leukocyte Adhesion to Human Induced Pluripotent Stem Cell-derived Endothelial Cells (hiPSC-ECs)

scientific article published on 26 November 2018

Model systems for cardiovascular regenerative biology

scientific article published on April 2013

Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes

scientific article

Modulation of functional and optimal (Na+-K+)ATPase activity during the cell cycle of neuroblastoma cells

scientific article published on 01 April 1981

Modulations of Na+ transport during the cell cycle of neuroblastoma cells

scientific article published on 01 July 1982

Molecular cloning, genetic mapping, and developmental expression of a bovine transforming growth factor beta (TGF-β) type I receptor ⬇️

scientific article published on January 1, 1998

Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction

scientific article published in January 2007

Mouse embryonic stem cells with aberrant transforming growth factor β signalling exhibit impaired differentiation in vitro and in vivo ⬇️

scientific article published on July 1, 1998

Myocardial tissue engineering: in vitro models

scientific article published on March 2014

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

scientific article published on 10 April 2018

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

scientific article published on 23 October 2011

NOBEL 2012 Physiology or medicine: Mature cells can be rejuvenated

scientific article published in December 2012

New perspectives on regeneration of the heart

scientific article published on 01 September 2011

Nitric oxide signaling in oxytocin-mediated cardiomyogenesis

scientific article published on 30 November 2006

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

scientific article published in October 2010

Organization of non-muscle myosin during early murine embryonic differentiation ⬇️

scientific article published on May 1, 1992

Organs-on-chips: into the next decade

scientific article published on 10 September 2020

Origin and use of embryonic and adult stem cells in differentiation and tissue repair

scientific article

Origins and fates of cardiovascular progenitor cells

scientific article published on February 2008

PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function.

scientific article published on 12 December 2013

Patterning the heart, a template for human cardiomyocyte development

scientific article published on 01 July 2006

Personalised organs-on-chips: functional testing for precision medicine

scientific article published on 01 January 2019

Perspectives on the Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Biomedical Research

scholarly article by Christine Mummery published 11 December 2018 in Stem Cell Reports

Phosphorylation dynamics during early differentiation of human embryonic stem cells.

scientific article published in August 2009

Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells

scientific article published on 20 May 2008

Pluripotent stem cell derived cardiovascular progenitors--a developmental perspective

scientific article

Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development

scientific article published on 22 June 2011

Pluripotent stem cell models of human heart disease

scientific article

Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI).

scientific article

Polycistronic lentivirus induced pluripotent stem cells from skin biopsies after long term storage, blood outgrowth endothelial cells and cells from milk teeth

scientific article published in February 2013

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.

scientific article published on 27 April 2009

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

scientific article published on 07 April 2016

Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

scientific article

Progenitor cells for cardiac repair

scientific article published on 21 December 2006

Prospects for pluripotent stem cell-derived cardiomyocytes in cardiac cell therapy and as disease models

scientific article published on July 2009

Proteome Biology of Stem Cells

scientific article published on 01 January 2008

Proteome biology of stem cells

Proteomic analysis of stem cell differentiation and early development

scientific article published on March 2012

Proteomics and human embryonic stem cells

scientific article published on 29 May 2008

Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts

scientific article published on 25 September 2018

Quantifying Ca2+ signaling and contraction in vascular pericytes and smooth muscle cells

scientific article published on 30 March 2019

Quantitative Analysis of Intracellular Ca Release and Contraction in hiPSC-Derived Vascular Smooth Muscle Cells

scientific article published on 07 March 2019

Rapid ionic events and the initiation of growth in serum-stimulated neuroblastoma cells.

scientific article published on March 1981

Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5A.

scientific article published in November 2016

Real time monitoring of BMP Smads transcriptional activity during mouse development

scientific article published in July 2008

Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; analysis of RPTPmu gene expression using LacZ knock-in mice

scientific article (publication date: June 2003)

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue

scientific article

Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alphavbeta5 integrin

scientific article published on 3 July 2008

Regenerative medicine funding policies in Europe and The Netherlands

scientific article published on 5 January 2017

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin

scientific article published in March 2004

Regulation of intracellular pH during the G1/S-phase transition of the neuroblastoma cell cycle

scientific article published in February 1988

Regulation of stem cell therapies under attack in Europe: for whom the bell tolls

scientific article published on 3 May 2013

Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations

scientific article published on 20 March 2015

Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes

scientific article published on 07 September 2012

Reprogramming Urine-Derived Cells using Commercially Available Self-Replicative RNA and a Single Electroporation

scientific article published on 01 December 2020

Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome

scientific article published on 4 April 2007

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.

scientific article published on 4 May 2014

SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development

scientific article published in February 2007

Scalable microphysiological system to model three-dimensional blood vessels

scientific article published on 21 June 2019

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

scientific article

Screening for cytotoxicity in neuroblastoma cells. I. Dependence of growth inhibition on the presence of serum

scientific article published on 01 September 1983

Screening for cytotoxicity in neuroblastoma cells. II. Growth inhibition: cell death or impaired cell cycle progression?

scientific article published on 01 September 1983

Secretion of transforming growth factor-beta isoforms by embryonic stem cells: isoform and latency are dependent on direction of differentiation.

scientific article published on August 1993

Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes

scientific article

Shedding new light on the mechanism underlying stem cell therapy for the heart

scientific article published on July 2011

Simultaneous measurement of contraction, voltage and calcium in HIPSC-CMS for the detection of inotropic effects under blinded conditions

scientific article published on 01 September 2019

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

scientific article published on 20 September 2019

Small molecule absorption by PDMS in the context of drug response bioassays.

scientific article published on 14 November 2016

Smooth muscle diversity from human pluripotent cells

scientific article published on 8 February 2012

SnapShot: Key Advances in hiPSC Disease Modeling

scientific article

Sorting cardiomyocytes: a simple solution after all?

scientific article published on 01 January 2010

Sox2 transduction enhances cardiovascular repair capacity of blood-derived mesoangioblasts

scientific article published on 25 February 2010

Spatial and temporal expression of the β1D integrin during mouse development ⬇️

scientific article published on December 1, 1997

Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins

scientific article published on 25 August 2004

Spotlight on stem cells--makes old hearts fresh

scientific article published on 01 May 2003

Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives

scientific article published on 12 March 2018

Stage-specific appearance of the mouse antigen TEC-3 in normal and nuclear transfer bovine embryos: re-expression after nuclear transfer.

scientific article published in January 1994

Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades

scientific article published on 23 February 2012

Stem cell research: immortality or a healthy old age?

scientific article

Stem cells: Cloning human embryos

scientific article published on 01 June 2013

Stem-cell-based therapy and lessons from the heart

scientific article published on May 2008

Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones

scientific article published on 13 May 2014

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes

scientific article published in January 2017

Survey of neuropeptide gene expression in tumor cell lines.

scientific article published on January 1992

Synthesis and regulation of leukaemia inhibitory factor in cultured bovine oviduct cells by hormones

scientific article published on 01 March 1998

TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT

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TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro

scientific article published in November 2007

Targeting the K<sub>v</sub>11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives

scientific article published on 21 November 2020

Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells

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Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

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The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays

scientific article published on 29 November 2018

The Next Chapter for Stem Cell Reports

The avian embryo to study development of the cardiac conduction system

scientific article published on 5 February 2016

The cancer's gone, but did chemotherapy damage your heart?

scientific article published on 26 May 2016

The cell cycle, cell death, and cell morphology during retinoic acid-induced differentiation of embryonal carcinoma cells

scientific article published on 01 August 1984

The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease

scientific article published on 12 May 2015

The human adult cardiomyocyte phenotype.

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The role of TGF-beta production in growth inhibition of breast-tumor cells by progestins.

scientific article published on March 1995

The time is right: proteome biology of stem cells

scientific article published on March 2008

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

scientific article published on 09 March 2017

Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device

scientific article published on September 2013

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

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Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

scientific article published on 24 July 2015

Transforming growth factor-beta in the early mouse embryo: implications for the regulation of muscle formation and implantation

scientific article published in January 1993

Transforming youth mental health services in a large urban centre: ACCESS Open Minds Edmonton

scientific article published on 01 June 2019

Transplantation of cells for cardiac repair

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Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish

scientific article published on 15 December 2007

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

scientific article published on 17 June 2020

Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?

scientific article published on 10 September 2019

Using Cardiovascular Cells from Human Pluripotent Stem Cells for COVID-19 Research: Why the Heart Fails

scientific article published on 27 November 2020

Variants of the alpha 6 beta 1 laminin receptor in early murine development: distribution, molecular cloning and chromosomal localization of the mouse integrin alpha 6 subunit

scientific article published on May 1993

Vascular Tumor Recapitulated in Endothelial Cells from hiPSCs Engineered to Express the <i>SERPINE1-FOSB</i> Translocation

scientific article published on 22 December 2020

Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo

Visceral endoderm induces specification of cardiomyocytes in mice

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Voices of biotech

scientific article published on March 2016

Welcome to stem cell reports

scientific article published on 4 June 2013

What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease

scientific article published on 01 May 2015

What if stem cells turn into embryos in a dish?

scientific article published in September 2015

Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart

scientific article published on 5 December 2017

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