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List of works by Donatella Del Bufalo

1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

scientific article published on 08 July 2014

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

scientific article published on 21 December 2015

A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function

scientific article published on 13 November 2017

Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.

scientific article published on 11 February 2016

Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.

scientific article

BCL-XL overexpression promotes tumor progression-associated properties.

scientific article published on 13 December 2017

BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.

scientific article published on 8 July 2013

Bcl-2 has differing effects on the sensitivity of breast cancer cells depending on the antineoplastic drug used.

scientific article published on December 2002

Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity.

scientific article

Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.

scientific article

CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.

scientific article

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.

scientific article

Detection of P-glycoprotein in the Golgi apparatus of drug-untreated human melanoma cells.

scientific article

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125

scientific article

Dual promoter usage as regulatory mechanism of let-7c expression in leukemic and solid tumors.

scientific article published on 17 March 2014

Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer

scientific article published on 16 December 2018

Endothelin-1 acts as a survival factor in ovarian carcinoma cells

scientific article published on 01 August 2002

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

scientific article published in March 2002

Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.

scientific article

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma

scientific article published on 16 September 2020

Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression.

scientific article

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations

scientific article published on August 2009

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

scientific article published on 08 February 2016

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

scientific article

Hypoxia-dependent drivers of melanoma progression

scientific article published in 2021

Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.

scientific article published on 26 August 2008

Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model.

scientific article published on 26 September 2017

Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells.

scientific article

Involvement of RB gene family in tumor angiogenesis.

scientific article published on August 2006

Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma

scientific article published on 11 September 2008

LMNA knock-down affects differentiation and progression of human neuroblastoma cells

scientific article

Lonidamine causes inhibition of angiogenesis-related endothelial cell functions

scientific article

Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.

scientific article published on September 1996

Lost in translation: bridging the gap between cancer research and effective therapies.

scientific article

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages

scientific article published on 01 April 2020

Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity

scientific article published on December 2017

Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression

scientific article published on 01 August 2007

N-methylformamide affects spontaneous metastases of 3LL lines and increases natural killer activity of tumor-bearing mice

scientific article published in March 1990

N-methylformamide as a potential therapeutic approach in colon cancer.

scientific article published on February 1994

N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells.

scientific article

N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics.

scientific article published on 18 August 2014

NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis

scientific article

Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain

scientific article published on 16 February 2017

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression

scientific article

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

scientific article published on 21 February 2017

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

scientific article published on 24 September 2018

Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin

scientific article published on 01 July 1994

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma

scientific article published on 05 September 2019

Reconstitution of hTERT restores tumorigenicity in melanoma-derived c-Myc low-expressing clones

scientific article published on 01 May 2002

Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth

scientific article published on March 2013

Retracted: Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90

retracted article

Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb

scientific article published on 19 November 2018

Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization

scientific article published on 18 September 2017

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

scientific article

TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo.

scientific article published on 2 December 2014

Targeting hypoxia in tumor: a new promising therapeutic strategy

scientific article published on 10 January 2020

Telomere dysfunction increases cisplatin and ecteinascidin-743 sensitivity of melanoma cells

scientific article published in March 2003

The Combination of the M2 Muscarinic Receptor Agonist and Chemotherapy Affects Drug Resistance in Neuroblastoma Cells

scientific article published on 10 November 2020

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.

scientific article published on 27 September 2009

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms

scientific article

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target

scientific article

The thiazole derivative CPTH6 impairs autophagy

scientific article published on 7 March 2013

Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha

scientific article

Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.

scientific article

Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

scientific article published on November 2003

VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling

scientific article

ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells

scientific article published in March 2002

miR-211 and MITF modulation by Bcl-2 protein in melanoma cells.

scientific article published on 24 November 2015

microRNA-378a-5p iS a novel positive regulator of melanoma progression

scientific article published on 14 February 2020

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.

scientific article published on December 2001

tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells

scientific article published on 25 March 2013

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