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List of works by Joachim Frank

A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM.

scientific article

A clarification of the terms used in comparing semi-automated particle selection algorithms in Cryo-EM ⬇️

scientific article published on March 21, 2011

A cryo-electron microscopic study of ribosome-bound termination factor RF2

scientific article

A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation

scientific article

Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.

scientific article published on May 2015

Advances in the field of single-particle cryo-electron microscopy over the last decade

scientific article

An Unbiased cDNA Library Prepared from IsolatedAplysiaSensory Neuron Processes Is Enriched for Cytoskeletal and Translational mRNAs ⬇️

scientific article published on October 15, 2003

Author Correction: Structure of human GABAB receptor in an inactive state

scientific article published on 15 July 2020

Automated acquisition of cryo-electron micrographs for single particle reconstruction on an FEI Tecnai electron microscope

scientific article

Automated particle picking for low-contrast macromolecules in cryo-electron microscopy

scientific article

CTF Challenge: Result summary.

scientific article published on 23 April 2015

Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit

scientific article

Climate change and the integrity of science

scientific article

Comprehensive Molecular Structure of the Eukaryotic Ribosome

scientific article

Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM.

scientific article

Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process

scientific article

Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex ⬇️

scientific article published on October 22, 2012

Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1.

scientific article published on 4 June 2013

Cryo-EM visualization of transfer messenger RNA with two SmpBs in a stalled ribosome

scholarly article

Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation

scientific article

Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns

scientific article published on 02 June 2010

Definition and estimation of resolution in single-particle reconstructions

scientific article published on July 2010

Displaying 3D data on RNA secondary structures: coloRNA.

scientific article

Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation

scientific article

Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy

scientific article

Dynamical features of the Plasmodium falciparum ribosome during translation.

scientific article

Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM

scientific article

Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy

scientific article published on 14 May 2015

Electron microscopy of functional ribosome complexes

scientific article

Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements

scientific article

Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu

scientific article

Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy

scientific article

EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics

scientific article

Femtosecond dark-field imaging with an X-ray free electron laser

scientific article

Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics

scientific article

Folding kinetics and structure of OEP16.

scientific article published on March 2004

Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight

scientific article

From DNA to proteins via the ribosome: structural insights into the workings of the translation machinery

scientific article published on April 2010

Functional conformations of the L11-ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations

scientific article

Generalized single-particle cryo-EM--a historical perspective

scientific article

Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit

scientific article

High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome

scientific article

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

scientific article

Integrity of the P-site is probed during maturation of the 60S ribosomal subunit ⬇️

scientific article published on June 11, 2012

Intermediate states during mRNA–tRNA translocation ⬇️

scientific article published on August 17, 2012

Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy

scientific article

Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication

scientific article published on December 2003

Locking and unlocking of ribosomal motions

scientific article

Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel

scientific article published on 01 June 2020

Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)

scientific article

Molecular dynamics of EF‐G during translocation ⬇️

scientific article published on March 1, 2011

New Opportunities Created by Single-Particle Cryo-EM: The Mapping of Conformational Space

scientific article

Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis

scientific article published on 8 February 2017

Outcome of the first electron microscopy validation task force meeting

scientific article (publication date: 8 February 2012)

POLARIS: Path of Least Action Analysis on Energy Landscapes

scientific article published on 20 February 2020

Particle migration analysis in iterative classification of cryo-EM single-particle data

scientific article

Particle-verification for single-particle, reference-based reconstruction using multivariate data analysis and classification

scientific article

Preparation of macromolecular complexes for cryo-electron microscopy

scientific article

Propagation of Conformational Coordinates Across Angular Space in Mapping the Continuum of States from Cryo-EM Data by Manifold Embedding

scientific article published on 02 April 2020

Quantitative Characterization of Domain Motions in Molecular Machines

scientific article published on 15 February 2017

Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome

scientific article

RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

scientific article

Recent progress in the crystallographic studies of photosystem II.

scientific article published on April 2010

Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

scientific article

Reference-free particle selection enhanced with semi-supervised machine learning for cryo-electron microscopy

scientific article

Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome

scientific article

Retrieving functional pathways of biomolecules from single-particle snapshots

scientific article published on 18 September 2020

Ribosome dynamics: insights from atomic structure modeling into cryo-electron microscopy maps

scientific article

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

scientific article

SPIRE: the SPIDER reconstruction engine

scientific article

Scaffolding as an Organizing Principle in Trans-translation: THE ROLES OF SMALL PROTEIN B AND RIBOSOMAL PROTEIN S1

scientific article

Single-particle imaging of macromolecules by cryo-electron microscopy

scientific article

Single-particle reconstruction of biological macromolecules in electron microscopy--30 years

scientific article

Single-particle structure determination by correlations of snapshot X-ray diffraction patterns

scientific article

Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits

scientific article

Structural Basis for Gating and Activation of RyR1.

scientific article

Structural characterization of mRNA-tRNA translocation intermediates

scientific article

Structural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryogenic electron microscopy

scientific article

Structural insights into cognate versus near-cognate discrimination during decoding

scientific article

Structural insights on the translation initiation complex: ghosts of a universal initiation complex

scientific article

Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit

scientific article published on 10 October 2016

Structure and dynamics of a processive Brownian motor: the translating ribosome

scientific article

Structure of a mammalian ryanodine receptor

scientific article

Structure of frozen-hydrated triad junctions: a case study in motif searching inside tomograms

scientific article

Structure of human GABAB receptor in an inactive state

scientific article published on 24 June 2020

Structure of mammalian eIF3 in the context of the 43S preinitiation complex

scientific article

Structure of the E. coli protein-conducting channel bound to a translating ribosome

scientific article

Structure of the STRA6 receptor for retinol uptake

scientific article

Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29

scientific article

Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP

scientific article

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

scientific article

Study of the structural dynamics of the E coli 70S ribosome using real-space refinement

scientific article

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle

scientific article

The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs

scientific article published on 14 October 2019

The Ribosome Comes Alive ⬇️

scientific article published on June 18, 2010

The cryo-EM structure of a translation initiation complex from Escherichia coli

scientific article

The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins

scientific article

The group II intron ribonucleoprotein precursor is a large, loosely packed structure

scientific article

The mechanism of translation

scientific article published on March 2017

The process of mRNA-tRNA translocation

scientific article

The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer

scientific article

The structure of the 80S ribosome from Trypanosoma cruzi reveals unique rRNA components

scientific article

The translation elongation cycle-capturing multiple states by cryo-electron microscopy

scientific article published in March 2017

Three-dimensional imaging of biological complexity

scientific article

Time-resolved imaging of macromolecular processes and interactions

scientific article

Toward an understanding of the structural basis of translation

scientific article

Transfer RNA in the hybrid P/E state: correlating molecular dynamics simulations with cryo-EM data

scientific article

Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromolecule

scientific article published on 31 October 2015

Visualization of a group II intron in the 23S rRNA of a stable ribosome

scholarly article

Visualization of macromolecular complexes using cryo-electron microscopy with FEI Tecnai transmission electron microscopes

scientific article

Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications

scientific article

Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy

scientific article

Visualizing the transfer-messenger RNA as the ribosome resumes translation ⬇️

scientific article published on October 12, 2010

Visualizing tmRNA entry into a stalled ribosome

scientific article

Whither Ribosome Structure and Dynamics Research? (A Perspective).

scientific article published on 10 May 2016

tmRNA on its way through the ribosome: two steps of resume, and what next?

scientific article

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