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List of works by Thomas Quertermous

A TNF variant that associates with susceptibility to musculoskeletal disease modulates thyroid hormone receptor binding to control promoter activation

scientific article

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A long noncoding RNA protects the heart from pathological hypertrophy

scientific article

A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

scientific article published on 23 October 2007

Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure

scientific article

Admixture mapping of quantitative trait loci for blood lipids in African-Americans

scientific article published on 20 March 2009

Advances in Transcriptomics: Investigating Cardiovascular Disease at Unprecedented Resolution

scientific article published in April 2018

Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts

scientific article published on 31 August 2017

An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies

scientific article published on July 2010

An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study

scientific article published in April 2005

An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program

scientific article

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity

scientific article

Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms

scientific article

Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells

scientific article

Apelin is necessary for the maintenance of insulin sensitivity

scientific article

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

scientific article

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

scientific article

Apelin-APJ signaling in retinal angiogenesis

scientific article published on October 2008

Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development

scientific article published on 19 April 2013

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

scientific article

Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study

scientific article published on 20 June 2007

CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study

scientific article published on 11 August 2017

Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes

scientific article

Characterizing the admixed African ancestry of African Americans

scientific article published in 2009

Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.

scientific article

Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease

scientific article

Circulating peptide prevents preeclampsia

scientific article published in August 2017

Clinical Utility of a Novel Coronary Heart Disease Risk‐Assessment Test to Further Classify Intermediate‐Risk Patients ⬇️

scientific article published on August 8, 2013

Clinical interpretation and implications of whole-genome sequencing

scientific article published in March 2014

Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption

scientific article

Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparison of developmental endothelial locus-1 angiogenic factor with vascular endothelial growth factor in a porcine model of cardiac ischemia

scientific article published in October 2003

Coronary Artery Disease and Its Risk Factors: Leveraging Shared Genetics to Discover Novel Biology

scientific article published on January 2016

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation

scientific article

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment

scientific article published on November 2008

Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3).

scientific article

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

scientific article

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

scientific article

Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia

scientific article published on 23 February 2004

Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli

scientific article published on 22 December 2005

Discovery and refinement of loci associated with lipid levels

scientific article

Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus

scientific article

Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension

scientific article

Dissecting the causal genetic mechanisms of coronary heart disease

scientific article published on May 2014

Distribution of the number of false discoveries in large-scale family-based association testing with application to the association between PTPN1 and hypertension and obesity

scientific article published on 29 December 2010

Effect of Common Genetic Variants of Growth Arrest-Specific 6 Gene on Insulin Resistance, Obesity and Type 2 Diabetes in an Asian Population

scientific article published on 18 August 2015

Endogenous regulation of cardiovascular function by apelin-APJ.

scientific article published on 18 September 2009

Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte-endothelial interaction

scientific article published on 18 April 2010

Endothelial lipase is a major determinant of HDL level

scientific article

Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages

scientific article published on 29 August 2007

Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice

scientific article

Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation

scientific article published on 13 October 2004

Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice

scientific article

Endothelial lipase: a new lipase on the block

scientific article

Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development

scientific article published on 14 August 2013

Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

scientific article published on 4 March 2016

Erratum to: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells

scientific article published on 9 February 2012

FGF-1 enhanced cardiogenesis in differentiating embryonal carcinoma cell cultures, which was opposite to the effect of FGF-2.

scientific article published on April 2003

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

scientific article

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

scientific article published on 22 May 2017

From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details

scientific article

Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis

scientific article published on 17 October 2007

Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci

scholarly article by Boxiang Liu et al published 18 August 2018 in American Journal of Human Genetics

Genetic epistasis of adiponectin and PPARgamma2 genotypes in modulation of insulin sensitivity: a family-based association study

scientific article

Genetic evidence of assortative mating in humans

article

Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology

scientific article

Genetic targeting of sprouting angiogenesis using Apln-CreER.

scientific article

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

scientific article published on February 2013

Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

scientific article

Genetics and Genomics of Coronary Artery Disease

scientific article published in October 2016

Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium

scientific article

Genome-wide copy number variation analysis identified deletions in SFMBT1 associated with fasting plasma glucose in a Han Chinese population

scientific article published on 8 August 2017

Genome-wide expression dynamics during mouse embryonic development reveal similarities to Drosophila development

scientific article

Genome-wide expression profiling of a cardiac pressure overload model identifies major metabolic and signaling pathway responses

scientific article published on December 2004

Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis

scientific article published in March 2005

Glia maturation factor-gamma is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization

scientific article

HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes

scientific article published on 18 September 2007

Hepatic proprotein convertases modulate HDL metabolism

scientific journal article

Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe Study

scientific article published on May 2007

High-sensitivity cardiac troponin I and incident coronary heart disease among asymptomatic older adults

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects.

scientific article published on 14 June 2018

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

scientific article published on 23 March 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

scientific article published on 4 January 2016

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

scientific article

Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2

scientific article

Identification of endothelial cell genes by combined database mining and microarray analysis

scientific article published on 13 May 2003

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries

scientific article published in June 2003

Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins

scientific article

In vivo bioluminescence imaging of inducible nitric oxide synthase gene expression in vascular inflammation

scientific article

In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure

scientific article

In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium

scientific article

Increased Bone Mass in Mice Lacking the Adipokine Apelin ⬇️

scientific article published on April 12, 2013

Increased expression of endothelial lipase in rat models of hypertension

scientific article published in June 2005

Increased rate of hair regrowth in mice with constitutive overexpression of Del1.

scientific article

Inducible and selective transgene expression in murine vascular endothelium

scientific article

Insulin resistance independently predicts the progression of coronary artery calcification

scientific article

Insulin resistance: regression and clustering

scientific article (publication date: 2014)

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

scientific article

Interpreting whole-genome sequencing--reply

scientific article published in July 2014

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program

scientific article

Load-dependent effects of apelin on murine cardiomyocytes

scientific article published on 18 September 2017

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation

scientific article

Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp

scientific article

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?

scientific article published on 17 October 2006

MicroRNA-26a is a novel regulator of vascular smooth muscle cell function

scientific article

Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms

scientific article published on January 2004

Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function

scientific article

Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli

scientific article

Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.

scientific article published on 18 November 2004

Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice

scientific article published on October 2016

Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1

article

Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1.

scientific article

Network analysis of human in-stent restenosis

scientific article published on 04 December 2006

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction

scientific article published on 8 September 2003

Ontogeny of apelin and its receptor in the rodent gastrointestinal tract

scientific article

Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery

scientific article published in December 2005

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

scientific article

Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice

scientific article published on 12 May 2015

Pancreatitis activates pancreatic apelin-APJ axis in mice ⬇️

scientific article published on May 16, 2013

Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1-FoxM1 complex

scientific article published on 06 September 2016

Pathway analysis of coronary atherosclerosis

scientific article published on 07 June 2005

Peroxisome proliferator-activated receptor gamma polymorphisms and coronary heart disease

scientific article published on December 2009

Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells

scientific article

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

scientific article published on 28 July 2016

Physical inactivity is an important lifestyle determinant of insulin resistance in hypertensive patients

scientific article

Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation

scientific article

Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease

article

Proteomic profiles of serum inflammatory markers accurately predict atherosclerosis in mice

scientific article

Racial variation in lipoprotein-associated phospholipase A₂ in older adults

scientific article

Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort

scientific article published in March 2012

Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis

scientific article published on 11 February 2010

Role of endothelial lipase in plasma HDL levels in a murine model of hypertriglyceridemia

scientific article published on 11 August 2009

Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings

scientific article published in March 2003

Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data

scientific article

Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease

scientific article published on 03 May 2005

Statin and beta-blocker therapy and the initial presentation of coronary heart disease

scientific article (publication date: 21 February 2006)

Study of exonic variation identifies incremental information regarding lipid-related and coronary heart disease genes

scientific article published on August 2014

Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course

scientific article published on 28 September 2015

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

scientific article published on 28 April 2008

Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

scientific article published on 14 May 2015

Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure

scientific article

TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression

article

Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivo

scientific article

Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration

scientific article published on 23 January 2009

Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment

scientific article published on 14 December 2016

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The adhesion molecule esam1 is a novel hematopoietic stem cell marker

scientific article

The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model

scientific article

The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation

scientific article

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program

scientific article

The negative correlation between plasma adiponectin and blood pressure depends on obesity: a family-based association study in SAPPHIRe

scientific article published on 7 February 2008

Therapeutic lymphangiogenesis with human recombinant VEGF-C.

scientific article published on 18 October 2002

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population

scientific article published on 08 September 2013

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

scientific article

Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation

scientific article published on 31 August 2004

Transcriptional profiling of the heart reveals chamber-specific gene expression patterns

scientific article

Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality

scientific article

Transcriptome-wide association studies: opportunities and challenges

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells

scientific article

Tree-structured supervised learning and the genetics of hypertension

scholarly article

Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program

scientific article published on 19 September 2005

Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse

scientific article

Use of high throughput genomic tools for the study of endothelial cell biology

scientific article

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