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List of works by Anke Tönjes

(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distribution

scientific article published on 30 May 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

scientific article

A novel FoxD3 Variant Is Associated With Vitiligo and Elevated Thyroid Auto-Antibodies

scientific article published on 12 August 2015

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

Adipocytokines are not associated with gestational diabetes mellitus but with pregnancy status

scientific article published on 10 April 2020

Adipokine Pattern in Subjects with Impaired Fasting Glucose and Impaired Glucose Tolerance in Comparison to Normal Glucose Tolerance and Diabetes ⬇️

scientific article published on November 9, 2010

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity

scientific article published on 05 June 2009

Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ).

scientific article published on 15 April 2015

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels

scientific article published on 12 June 2013

Assay-dependent variability of serum insulin levels during oral glucose tolerance test: influence on reference intervals for insulin and on cut-off values for insulin sensitivity indices

scientific article published in January 2008

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

scientific article published on January 2010

Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals

scientific article published in November 2006

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

scientific article

Atg7 Knockdown Reduces Chemerin Secretion in Murine Adipocytes

scientific article published on 01 November 2019

Beneficial effects of a 4-week exercise program on plasma concentrations of adhesion molecules

scientific article published on 01 March 2007

Betatrophin levels are increased in women with gestational diabetes mellitus compared to healthy pregnant controls

scientific article published on 07 April 2015

Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots

scientific article

Circulating Adipokine VASPIN Is Associated with Serum Lipid Profiles in Humans

scientific article published on 18 March 2019

Circulating cell adhesion molecules in metabolically healthy obesity

scientific article published on 01 September 2020

Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Contemporary paternal genetic landscape of Polish and German populations: from early medieval Slavic expansion to post-World War II resettlements

scientific article (publication date: 12 September 2012)

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

DNA methylation patterns reflect individual's lifestyle independent of obesity

scientific article published on 01 June 2022

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Does retinol-binding protein 4 cause or reflect fatty liver disease?

scientific article published on 01 July 2008

Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index

scientific article published on 31 July 2015

Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance

scientific article published in April 2006

Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression

scientific article published on 29 October 2009

Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts

scientific article

Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children

scientific article

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression

scientific article published on 29 August 2007

Effects of hyperthyroidism on adipose tissue activity and distribution in adults

scientific article published on 06 October 2020

Effects of psychological eating behaviour domains on the association between socio-economic status and BMI.

scientific article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Failure to achieve disease control in acromegaly: cause analysis by a registry-based survey

scientific article published on 19 January 2015

Fat mass and obesity-associated (fto) gene and alcohol intake

scientific article published on 17 April 2012

Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans

scientific article published on 18 January 2013

Frequency of AIP gene mutations in young patients with acromegaly: a registry-based study

scientific article

Gene expression analysis reveals evidence for inactivation of the TGF-beta signaling cascade in autonomously functioning thyroid nodules

scientific article

Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training

scientific article

Genetic analyses of bone morphogenetic protein 2, 4 and 7 in congenital combined pituitary hormone deficiency.

scientific article

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity

scientific article

Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus

scientific article published on 25 January 2013

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in AKR1B10 associate with human eating behavior

scientific article

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

scientific article published on 03 September 2009

Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity

scientific article

Genetically programmed changes in transcription of the novel progranulin regulator

scientific article published on 03 July 2020

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

scientific article

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

scientific article published on 27 November 2017

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

scientific article

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Genomic insights into the origin of farming in the ancient Near East

scientific article (publication date: 25 August 2016)

Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis

scientific article published on 22 August 2014

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

scientific article published on 01 March 2020

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation

scientific article

Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots

scientific article published on 13 July 2020

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Impaired enteral levothyroxine absorption in hypothyroidism refractory to oral therapy after thyroid ablation for papillary thyroid cancer: case report and kinetic studies

scientific article published in October 2006

Incidence of myocardial infarction and stroke in acromegaly patients: results from the German Acromegaly Registry

scientific article published on 14 August 2017

Increased circulating cell-free DNA in insulin resistance

scientific article published on 20 June 2018

Indications for potential parent-of-origin effects within the FTO gene

scientific article

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood

scientific article

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Involvement of the chemokine-like receptor GPR33 in innate immunity

scientific article

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

scientific article

Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene

scientific article published on 9 May 2008

Management of nicotinamide N-methyltransferase overexpression: inhibit the enzyme or reduce nicotinamide intake? Reply to Zhou S, Li D, Zhou Y [letter].

scientific article

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Metabolic effects of genetic variation in the human REPIN1 gene

scientific article published on 18 June 2018

Multiple loci are associated with white blood cell phenotypes

scientific article

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

New loci associated with kidney function and chronic kidney disease

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

On the impact of relatedness on SNP association analysis

scientific article published on 6 December 2017

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians

scientific article published on 31 January 2008

Random Projection for Fast and Efficient Multivariate Correlation Analysis of High-Dimensional Data: A New Approach

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82

scientific article (publication date: 2011)

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Relationship between twelve adipocytokines and distinct components of the metabolic syndrome

scientific article published on 9 January 2018

Retinol-binding protein 4 and new adipocytokines in nonalcoholic fatty liver disease

scientific article published on June 2010

Role of genetic variants in ADIPOQ in human eating behavior

scientific article

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity

scientific article published in May 2010

Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis

scientific article published on 10 August 2011

Role of vaspin in human eating behaviour

scientific article

SGLT2: a potential target for the pharmacogenetics of Type 2 diabetes?

scientific article published on May 2013

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

scientific article

Serum levels of acylcarnitines are altered in prediabetic conditions

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Sialylation of human thyrotropin receptor improves and prolongs its cell-surface expression

scientific article published on 13 July 2005

Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations

scientific article published on 3 February 2015

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies

scientific article

Surprising thoracic tumour mass ⬇️

scientific article published on August 19, 2011

Systematic comparison of sporadic and syndromic pancreatic islet cell tumors

scientific article published on 5 October 2010

TAS2R38 and its influence on smoking behavior and glucose homeostasis in the German Sorbs

scientific article

THOC5: a novel gene involved in HDL-cholesterol metabolism

scientific article published on 10 September 2013

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The Effects of Thyroid Hormones on Gene Expression of Acyl-Coenzyme A Thioesterases in Adipose Tissue and Liver of Mice

scientific article

The Incidence of Cancer Among Acromegaly Patients: Results From the German Acromegaly Registry

scientific article published on 5 August 2015

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany

scientific article

The effect of ACACB cis-variants on gene expression and metabolic traits

scientific article

The genetic structure of the world's first farmers

The genetics of euthyroid familial goiter

scientific article

The role of rs2237781 within GRM8 in eating behavior

scientific article published on 23 June 2013

The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabetes risk

scientific article

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

scientific article published on 12 December 2016

Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans

scientific article published in February 2007

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Visfatin is a positive regulator of MCP-1 in human adipocytes in vitro and in mice in vivo

scientific article published on 24 December 2009

Widely Used Commercial ELISA Does Not Detect Precursor of Haptoglobin2, but Recognizes Properdin as a Potential Second Member of the Zonulin Family

scientific article published on 5 February 2018

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