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List of works by Claudia Langenberg

A Comprehensive Reanalysis Of Publicly Available GWAS Datasets Reveals An X Chromosome Rare Regulatory Variant Associated With High Risk For Type 2 Diabetes

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

scientific article published on 27 April 2015

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

scientific article

A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature

scientific article

A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study

scientific article published on 11 October 2017

A cross-platform approach identifies genetic regulators of human metabolism and health

scientific article published on 07 January 2021

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease

scientific article

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia.

scholarly article

Adult height and lung function as markers of life course exposures: associations with risk factors and cause-specific mortality

scientific article published on 22 November 2006

Adult socioeconomic position and the association between height and coronary heart disease mortality: findings from 33 years of follow-up in the Whitehall Study

scientific article published on 01 April 2005

Age at menarche and type 2 diabetes risk: the EPIC-InterAct study

scientific article

Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study

scientific article published on 10 December 2012

Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study

scientific article published on 8 May 2012

Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study.

scientific article

An amino acid profile to predict diabetes? ⬇️

scientific article published on April 1, 2011

An atlas of genetic scores to predict multi-omic traits

scientific article published on 29 March 2023

An atlas of genetic scores to predict multi-omic traits

Assessing the causal association of glycine with risk of cardio-metabolic diseases

scientific article published on 05 March 2019

Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis

scientific article published on October 2016

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study

scientific article

Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study

scientific article published on 17 November 2017

Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors

scientific article published on 01 December 2018

Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes

scientific article

Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study

scientific article published on 09 February 2016

Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study

scientific article

Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study

Association of adiponectin with coronary heart disease and mortality: the Rancho Bernardo study

scientific article

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children ⬇️

scientific article published on 22 April 2011

Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis

scientific article published in 2022

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of common genetic variants with age-related changes in fasting and postload glucose: evidence from 18 years of follow-up of the Whitehall II cohort

scientific article published on 25 March 2011

Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

scientific article published on 01 December 2018

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Birth weight and lipids in a national birth cohort study

scientific article

Birth weight, components of height and coronary heart disease: evidence from the Whitehall II study

scientific article published on 24 August 2006

Birthweight, childhood growth, and blood pressure at 43 years in a British birth cohort

scientific article published on 01 February 2004

Birthweight, childhood social class, and change in adult blood pressure in the 1946 British birth cohort

scientific article published on 01 October 2003

Cardiovascular death and the metabolic syndrome: role of adiposity-signaling hormones and inflammatory markers

scientific article published in June 2006

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

scientific article published on 28 December 2012

Central and total obesity in middle aged men and women in relation to lifetime socioeconomic status: evidence from a national birth cohort ⬇️

scientific article published on October 1, 2003

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

scientific article published on 20 September 2018

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

scholarly article published 11 February 2018

Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diabetes: results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-analysis of prospective studies

scientific article published on 15 April 2012

Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article published on 9 March 2018

Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis

Circulating selenium and prostate cancer risk: a Mendelian randomization analysis

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Commentary: Disentangling the association between short height and cardiovascular risk--genes or environment?

scientific article

Commentary: The association between height growth and cholesterol levels during puberty: implications for adult health

scientific article published in December 2003

Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study

scientific article published on 09 September 2009

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Components of height and blood pressure in childhood.

scientific article published on 10 January 2014

Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries

scientific article published on 26 November 2014

Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct

scientific article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

scientific article

Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article published on 30 March 2015

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

scientific article published on 17 December 2015

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis

scientific article

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

scientific article

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

scientific article

Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease

scientific article published in 2021

Diabetes and coronary heart disease in Filipino-American women: role of growth and life-course socioeconomic factors

scientific article published on March 2007

Dietary Protein Intake and Incidence of Type 2 Diabetes in Europe: The EPIC-InterAct Case-Cohort Study

article by Monique van Nielen et al published 10 April 2014 in Diabetes Care

Dietary glycemic index, glycemic load, and digestible carbohydrate intake are not associated with risk of type 2 diabetes in eight European countries

scientific article published on 28 November 2012

Dietary intakes of individual flavanols and flavonols are inversely associated with incident type 2 diabetes in European populations

scientific article published on 24 December 2013

Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study

scientific article

Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study

scientific article

Differential white blood cell count and type 2 diabetes: systematic review and meta-analysis of cross-sectional and prospective studies

scientific article

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

scientific article published on 26 September 2016

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay

scientific article

ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19

Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes

scientific article

Erratum. Dietary protein intake and incidence of type 2 diabetes in europe: the EPIC-InterAct case-cohort study. Diabetes Care 2014;37:1854-1862.

scientific article published on October 2015

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples

scientific article published on 20 March 2012

Evidence for Shared Genetic Aetiology Between Schizophrenia, Cardiometabolic, and Inflammation-Related Traits: Genetic Correlation and Colocalization Analyses

scientific article published in 2022

Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis

scientific article

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis

scientific article

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

article

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

scientific article

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

scientific article

Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease

scientific article published on 26 April 2016

Genetic Markers of Insulin Sensitivity and Insulin Secretion Are Associated With Spontaneous Postnatal Growth and Response to Growth Hormone Treatment in Short SGA Children: the North European SGA Study (NESGAS)

article

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

scientific article

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of host proteins interacting with SARS-CoV-2

scientific article published on 01 July 2020

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits

scientific article

Genetic determinants of glucose homeostasis

scientific article published on April 2012

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

scientific article

Genetic evidence of assortative mating in humans

article

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

scientific article published on 18 November 2009

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic insights into biological mechanisms governing human ovarian ageing

scientific article

Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth

scientific article (publication date: 25 May 2010)

Genetic predisposition to obesity leads to increased risk of type 2 diabetes

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility

scientific article published on 27 March 2017

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the <i>GIPR</i> Region

scientific article published on 23 August 2021

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

scientific article published on 14 July 2016

Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations

scientific article published on 8 September 2017

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study

scientific article published on 13 November 2020

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

scientific article published on 4 May 2017

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

scientific article published on 09 July 2018

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide scan and fine-mapping of rare nonsynonymous associations implicates intracellular lipolysis genes in fat distribution and cardio-metabolic risk

article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

article

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

scientific article published on 11 May 2020

Genomic insights into the causes of type 2 diabetes

scientific article published on 01 June 2018

Ghrelin and bone: is there an association in older adults?: the Rancho Bernardo study

scientific article

Ghrelin and the metabolic syndrome in older adults.

scientific article published on 4 October 2005

Ghrelin, adiponectin, and leptin do not predict long-term changes in weight and body mass index in older adults: longitudinal analysis of the Rancho Bernardo cohort

scientific article published on 19 October 2005

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014

Higher immunoglobulin G antibody levels against cytomegalovirus are associated with incident ischemic heart disease in the population-based EPIC-Norfolk cohort

scientific article published on 8 October 2012

Household wealth and the metabolic syndrome in the Whitehall II study

scientific article published on December 2006

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

scientific article published on 28 September 2017

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

scientific article

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Impact of common variation in bone-related genes on type 2 diabetes and related traits

scientific article

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Individual and cumulative effect of type 2 diabetes genetic susceptibility variants on risk of coronary heart disease

Influence of height, leg and trunk length on pulse pressure, systolic and diastolic blood pressure

scientific article published on March 2003

Influence of short stature on the change in pulse pressure, systolic and diastolic blood pressure from age 36 to 53 years: an analysis using multilevel models

scientific article published on 15 April 2005

Integrating Genetics and the Plasma Proteome to Predict the Risk of Type 2 Diabetes

scientific article published on 08 October 2020

Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes: systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct

scientific article

Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study

scientific article published on 22 November 2017

Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies

scientific article

Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries.

scientific article published on 17 March 2018

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Life course body size and lipid levels at 53 years in a British birth cohort

scientific article published on March 2007

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

scientific article published in January 2018

Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies

scientific article

Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study

scientific article

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Lower educational level is a predictor of incident type 2 diabetes in European countries: The EPIC-InterAct study

scientific article published on 25 June 2012

MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai

scientific article

Mapping the serum proteome to neurological diseases using whole genome sequencing

scientific article published on 02 December 2021

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Mediterranean diet and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study: the InterAct project

scientific article

Mendelian Randomisation study of the influence of eGFR on coronary heart disease

scientific article published on 24 June 2016

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

scientific article

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance

scientific article

Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies

scientific article (publication date: October 2011)

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Mortality in adults aged 26-54 years related to socioeconomic conditions in childhood and adulthood: post war birth cohort study

scientific article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

scientific article published in 2022

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach

article

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Non-invasive risk scores for prediction of type 2 diabetes (EPIC-InterAct): a validation of existing models

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.

scientific article published on 17 November 2016

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

P128 Identification de nouveaux polymorphismes génétiques associés au risque de diabète de type 2 chez les obèses et non obèses européens

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease

scientific article published in August 2017

Plasma protein patterns as comprehensive indicators of health

scientific article published on 02 December 2019

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Prevalence and Regional Distribution of Autoantibodies Against GAD65Ab in a European Population Without Diabetes: The EPIC-InterAct Study

scientific article published on August 2015

Prevalence of angina in women versus men: a systematic review and meta-analysis of international variations across 31 countries

scientific article published on 17 March 2008

Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches.

scientific article published on 19 May 2018

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

scientific article published on 30 May 2018

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

scientific article published on 25 July 2019

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

scientific article

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

scientific article published on 29 January 2012

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

scientific article published on 29 June 2017

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare coding variants and X-linked loci associated with age at menarche

scientific article

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Regional fat depot masses are influenced by protein-coding gene variants

article

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans

scientific article published on 09 June 2016

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.

scientific article

Self-rated health and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition-InterAct study: a case-cohort study

scientific article published on 6 March 2013

Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis

scientific article published on 14 August 2017

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective investigation of Cancer-Norfolk cohort

scientific article published on 26 February 2013

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Sixty-five common genetic variants and prediction of type 2 diabetes

scientific article published on 4 December 2014

Smoking and long-term risk of type 2 diabetes: the EPIC-InterAct study in European populations

scientific article published on 21 October 2014

Social circumstances and education: life course origins of social inequalities in metabolic risk in a prospective national birth cohort

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

scientific article

Tea consumption and incidence of type 2 diabetes in Europe: the EPIC-InterAct case-cohort study

scientific article (publication date: 2012)

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study

scientific article

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis

scientific article published on 16 October 2020

The association between dietary energy density and type 2 diabetes in Europe: results from the EPIC-InterAct Study

scientific article

The association between dietary flavonoid and lignan intakes and incident type 2 diabetes in European populations: the EPIC-InterAct study

scientific article published on 15 October 2013

The association between prior infection with five serotypes of Coxsackievirus B and incident type 2 diabetes mellitus in the EPIC-Norfolk study

scientific article

The association of the mitochondrial DNA OriB variant (16184-16193 polycytosine tract) with type 2 diabetes in Europid populations

scientific article published on 24 May 2013

The current and potential health benefits of the National Health Service Health Check cardiovascular disease prevention programme in England: A microsimulation study.

scientific article published on 6 March 2018

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study

scientific article published on 9 May 2012

The trans-ancestral genomic architecture of glycemic traits

Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people

scientific article

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people

scientific article

Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study

scientific article

Type 2 diabetes–associated variants of the MT2melatonin receptor affect distinct modes of signaling

Underlying genetic models of inheritance in established type 2 diabetes associations

scientific article published on 14 July 2009

Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study

article by Dagmar Drogan et al published March 2015 in Clinical Chemistry

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

scientific article published on 22 February 2013

Usefulness of microalbuminuria versus the metabolic syndrome as a predictor of cardiovascular disease in women and men>40 years of age (from the Rancho Bernardo Study).

scientific article published on 07 March 2008

Using human genetics to understand the disease impacts of testosterone in men and women

scientific article published on 10 February 2020

Validity of a short questionnaire to assess physical activity in 10 European countries

scientific article published on 17 November 2011

Variants associated with expression have sex-differential effects on lung function

scientific article

Variants in MTNR1B influence fasting glucose levels

scientific article

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