List of works by Gonneke Willemsen

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio

scientific article published on 3 August 2017

72: A Genome Wide Association Study (GWAS) from a global cohort identifies common variants in FSHB and SMAD3 driving spontaneous human dizygotic twinning

A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families

scientific article

A fine-mapping study of 7 top scoring genes from a GWAS for major depressive disorder

scientific article

A genetic analysis of ambulatory cardiorespiratory coupling.

scientific article published in March 2005

A genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

scientific article

A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation

scientific article

A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine

scientific article published in October 2008

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

scientific article

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A powerful phenotype for gene-finding studies derived from trajectory analyses of symptoms of anxiety and depression between age seven and 18.

scientific article published on 3 September 2015

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A whole-genome scan for 24-hour respiration rate: a major locus at 10q26 influences respiration during sleep

scientific article

ADHD in Dutch adults: heritability and linkage study

scientific article published on 3 February 2011

Acute mental stress elicits delayed increases in circulating inflammatory cytokine levels

scientific article published in August 2001

Adolescent personality profiles, neighborhood income, and young adult alcohol use: a longitudinal study

scientific article

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

scientific article

Ambulatory measurement of the ECG T-wave amplitude

scientific article published on 13 August 2014

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

scientific article published on 8 December 2016

An Extended Twin-Pedigree Study of Neuroticism in the Netherlands Twin Register

scientific article published on 17 October 2017

An association between Epac-1 gene variants and anxiety and depression in two independent samples

scientific article

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

scientific article published on 13 June 2019

Are Migraine and Tension-Type Headache Genetically Related? An Investigation of Twin Family Data.

scientific article published in April 2018

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association between autozygosity and major depression: stratification due to religious assortment

scientific article published on 25 August 2013

Association of CRTC1 polymorphisms with obesity markers in subjects from the general population with lifetime depression

scientific article

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

scientific article published on 04 April 2013

Associations between ADH gene variants and alcohol phenotypes in Dutch adults

scientific article published in February 2010

Associations between smoking and caffeine consumption in two European cohorts

scientific article published on 09 January 2016

Assortative mating may explain spouses' risk of same disease

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Blood lipids influence DNA methylation in circulating cells

scientific article published on 27 June 2016

Body composition, smoking, and spontaneous dizygotic twinning

scientific article published on 4 December 2008

Borderline personality traits and substance use: genetic factors underlie the association with smoking and ever use of cannabis, but not with high alcohol consumption

scientific article published on December 2012

CNV Concordance in 1,097 MZ Twin Pairs

scientific article published on 12 January 2015

Causes of variation in the neutrophil-lymphocyte and platelet-lymphocyte ratios: a twin-family study

scientific article published on 03 October 2016

Cellular and mucosal immune reactions to mental and cold stress: associations with gender and cardiovascular reactivity.

scientific article published in March 2002

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

scientific article

Cohort profile: the Geoscience and Health Cohort Consortium (GECCO) in the Netherlands.

scientific article

Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci

scientific article

Combined genome scans for body stature in 6602 European twins: evidence for common Caucasian loci

Combined linkage and association analyses of the 124-bp allele of marker D2S2944 with anxiety, depression, neuroticism and major depression

scientific article published on 24 December 2005

Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

scientific article

Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp

scientific article (publication date: 2012)

Comparing low frequency heart rate variability and preejection period: Two sides of a different coin

Comparison of time and frequency domain measures of RSA in ambulatory recordings

scientific article published in March 2007

Competitiveness and hemodynamic reactions to competition

scientific article published in November 2002

Correction: DeepSAGE Reveals Genetic Variants Associated with Alternative Polyadenylation and Expression of Coding and Non-coding Transcripts

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins

scientific article published on 13 November 2015

DNA modification study of major depressive disorder: beyond locus-by-locus comparisons

scientific article

DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts

scientific article

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts

scientific article

Differential gene expression patterns between smokers and non-smokers: cause or consequence?

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Dizygotic twinning

scientific article

Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

scientific article

Early alcohol initiation and increased adult alcohol consumption: cause or indicator?

scientific article

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts

scientific article published in October 2017

Educational attainment influences levels of homozygosity through migration and assortative mating

scientific article

Effect of genome and environment on metabolic and inflammatory profiles

scientific article

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

scientific article published on 5 August 2015

Environmental factors determine where the Dutch live: results from the Netherlands twin register

scientific article published on August 2005

Environmental factors in obsessive-compulsive behavior: evidence from discordant and concordant monozygotic twins

scientific article

Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs

scientific article

Erratum to "Short communication: Genetic association between schizophrenia and cannabis use" [Drug Alcohol Depend. 171 (2017) 117-121].

scientific article published on 7 March 2017

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article published on 2 August 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Establishment of the Avera Twin Register in the Midwest USA.

scientific article

Estimating non-response bias in family studies: application to mental health and lifestyle

scientific article published in January 2004

Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms

scientific article

Ethical issues and GenomEUtwin

scientific article published in October 2003

Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression

scientific article

Exercise participation in adolescents and their parents: evidence for genetic and generation specific environmental effects

scientific article

Exposure to secondhand smoke and depression and anxiety: a report from two studies in the Netherlands

scientific article published on 31 August 2013

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Familial Resemblance for Serum Metabolite Concentrations — Corrigendum

scholarly article published in Twin Research and Human Genetics

Familial clustering of major depression and anxiety disorders in Australian and Dutch twins and siblings.

scientific article published in December 2005

Familial influences on basal salivary cortisol in an adult population

scientific article published on October 2005

Familial resemblance for loneliness

scientific article

Familial resemblance for serum metabolite concentrations

scientific article published on 28 August 2013

Familial resemblance of borderline personality disorder features: genetic or cultural transmission?

scientific article published in 2009

Familial twinning and fertility in Dutch mothers of twins

article by Chantal Hoekstra et al published 15 December 2008 in American Journal of Medical Genetics

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

scientific article

Frequency of truancy at high school: evidence for genetic and twin specific shared environmental influences

scientific article published on 30 May 2009

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Gene expression in major depressive disorder

scientific article

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

scientific article

Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling

scientific article published on 20 August 2016

Gene-environment interaction in adults' IQ scores: measures of past and present environment

scientific article published on 6 June 2008

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

scientific article published on March 2016

Genetic analyses benefit from using less heterogeneous phenotypes: an illustration with the hospital anxiety and depression scale (HADS).

scientific article published on April 2015

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental contributions to loneliness in adults: the Netherlands twin register study

scientific article

Genetic and environmental contributions to self-reported thoughts of self-harm and suicide

scientific article published on 7 December 2011

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODA

scientific article published on 13 July 2016

Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts.

scientific article

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.

scientific article published on 14 December 2016

Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

scientific article published on 23 June 2016

Genetic and environmental influences on the relationship between adult ADHD symptoms and self-reported problem drinking in 6024 Dutch twins

scientific article published on 3 March 2014

Genetic and environmental stability in attention problems across the lifespan: evidence from the Netherlands twin register

scientific article

Genetic architecture of circulating lipid levels

scientific article

Genetic architecture of the pro-inflammatory state in an extended twin-family design

scientific article

Genetic covariance structure of the four main features of borderline personality disorder

scientific article published on August 2010

Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults

scientific article

Genetic etiology of stability of attention problems in young adulthood

article published in 2005

Genetic evidence of assortative mating in humans

article

Genetic influences on handedness: data from 25,732 Australian and Dutch twin families

scientific article

Genetic regulation of growth in height and weight from 3 to 12 years of age: a longitudinal study of Dutch twin children

scientific article published in April 2007

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

scientific article

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

scientific article published on October 2013

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in RBFOX3 are associated with sleep latency

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

scientific article

Genome partitioning of genetic variation for height from 11,214 sibling pairs

scientific article published in October 2007

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

scientific article published on February 2016

Genome-Wide Scan for Blood Pressure in Australian and Dutch Subjects Suggests Linkage at 5P, 14Q, and 17P

article

Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder

scientific article published on 25 May 2017

Genome-wide analyses of borderline personality features

scientific article

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide analysis of DNA methylation in buccal cells: a study of monozygotic twins and mQTLs

scholarly article by Jenny van Dongen published in September 2018

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

scientific article published on 26 April 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

scholarly article by Johannes Waage et al published August 2018 in Nature Genetics

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

scientific article published on 09 December 2008

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability.

scientific article published on 16 April 2018

Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

scientific article published on 20 June 2017

Genome-wide association study of exercise behavior in Dutch and American adults

scientific article

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

article

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

scientific article published on 3 January 2018

Genome-wide association study of smoking initiation and current smoking

scientific article published on 05 March 2009

Genome-wide association uncovers shared genetic effects among personality traits and mood states

scientific article published on 24 May 2012

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands

scientific article published on June 2008

Genome-wide linkage scan for exercise participation in Dutch sibling pairs

article by Marleen H M De Moor et al published 15 August 2007 in European Journal of Human Genetics

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

scientific article published on 23 March 2016

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Geographical structure and differential natural selection among North European populations

scientific article published on 05 March 2009

Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men

article

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

scientific article

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

scientific article

Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio

scientific article published on 14 February 2017

Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample

scientific article

Heritability and Temporal Stability of Ambulatory Autonomic Stress Reactivity in Unstructured 24-Hour Recordings

scientific article published on 14 September 2015

Heritability and genome-wide linkage scan of subjective happiness

scientific article

Heritability and genomics of gene expression in peripheral blood

scientific article

Heritability and stability of resting blood pressure

scientific article published in October 2005

Heritability of Ambulatory Heart Rate Variability

article by Nina H.M. Kupper et al published 2 November 2004 in Circulation

Heritability of ECG Biomarkers in the Netherlands Twin Registry Measured from Holter ECGs

scientific article published on 29 April 2016

Heritability of Working in a Creative Profession

scientific article

Heritability of adult body height: a comparative study of twin cohorts in eight countries

scientific article

Heritability of body mass index: a comparison between the Netherlands and Spain.

scientific article published in October 2007

Heritability of cardiac vagal control in 24-h heart rate variability recordings: influence of ceiling effects at low heart rates

scientific article

Heritability of daytime ambulatory blood pressure in an extended twin design

scientific article published on 22 November 2004

Heritability of high sugar consumption through drinks and the genetic correlation with substance use.

scientific article published on 31 August 2016

Heritability of indices for cardiac contractility in ambulatory recordings

scientific article published on 27 June 2006

Heritability of lifetime ecstasy use.

scientific article

Heritability of liver enzyme levels estimated from genome-wide SNP data

scientific article

Heritability of metabolic syndrome traits in a large population-based sample

scientific article

Heritability of parturition timing: an extended twin design analysis.

scientific article published on 4 March 2008

Heritability of problem drinking and the genetic overlap with personality in a general population sample

scientific article published on 2 November 2011

Heritability of self-reported asthma and allergy: a study in adult Dutch twins, siblings and parents

scientific article published in April 2008

Heritability of self-reported phobic fear

scientific article

Heritability of smoking initiation and nicotine dependence

scientific article published on July 2005

Heritability of type-D personality

scientific article published on 31 August 2007

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility

scientific article published on 27 April 2016

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Identifying genetic variants for heart rate variability in the acetylcholine pathway

scientific article

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

Increases in alcohol consumption in women and elderly groups: evidence from an epidemiological study

scientific article

Individual Differences in Exercise Behavior: Stability and Change in Genetic and Environmental Determinants From Age 7 to 18.

scientific article published on 12 July 2016

Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairs

scientific article published on 31 October 2013

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

scientific article published on 2 January 2018

Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals

scientific article

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

scientific article published on 7 October 2014

LPAR1 and ITGA4 regulate peripheral blood monocyte counts

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale ensemble averaging of ambulatory impedance cardiograms

scientific article published in August 2003

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Life events and borderline personality features: the influence of gene-environment interaction and gene-environment correlation.

scientific article published in July 2010

Linkage analysis of smoking initiation and quantity in Dutch sibling pairs

scientific article published on January 2004

Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype

scientific article

Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations

scientific article published on 18 October 2011

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

scientific article (publication date: 2009)

Low Birth Weight in MZ Twins Discordant for Birth Weight is Associated with Shorter Telomere Length and lower IQ, but not Anxiety/Depression in Later Life

scientific article

Males do not reduce the fitness of their female co-twins in contemporary samples

scientific article

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

scientific article

Meta-analysis of genome-wide association for migraine in six population-based European cohorts

scientific article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect

scientific article published on 16 January 2013

Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging

scientific article

Migraine symptomatology and major depressive disorder

scientific article

Mode of conception of twin pregnancies: willingness to reply to survey items and comparison of survey data to hospital records

scientific article

Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci

scientific article

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Netherlands Twin Register: from twins to twin families

scientific article

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

Nine-year stability of type D personality: contributions of genes and environment.

scientific article published on 14 October 2010

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

scientific article

Non-additive and additive genetic effects on extraversion in 3314 Dutch adolescent twins and their parents

scientific article published in February 2008

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Partitioning the etiology of hoarding and obsessive-compulsive symptoms

scientific article published on 20 February 2014

Personality differences in monozygotic twins discordant for cannabis use.

scientific article published on December 2007

Personality trait similarity between spouses in four cultures

scientific article published on 28 July 2008

Personality, health and lifestyle in a questionnaire family study: a comparison between highly cooperative and less cooperative families

scientific article published in April 2007

Polygenic dissection of major depression clinical heterogeneity

scientific article

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

scientific article

Polygenic risk scores for schizophrenia and bipolar disorder predict creativity

scientific article published on 8 June 2015

Polygenic risk scores for smoking: predictors for alcohol and cannabis use?

scientific article

Poor replication of candidate genes for major depressive disorder using genome-wide association data

scientific article

Population structure, migration, and diversifying selection in the Netherlands

scientific article

Predictors of problem drinking in adolescence and young adulthood. A longitudinal twin-family study

scientific article published on 5 February 2009

Prevalence and trends of alcohol use and misuse among adolescents and young adults in the Netherlands from 1993 to 2000.

scientific article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

QTLs for height: results of a full genome scan in Dutch sibling pairs

scientific article published in October 2004

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions

scientific article published on 05 December 2012

Relative Telomere Repeat Mass in Buccal and Leukocyte-Derived DNA.

scientific article

Reliability of hematocrit during rest and stress in healthy adults.

scientific article published on 15 September 2007

Religious upbringing and neuroticism in Dutch twin families.

scientific article published in April 2007

Replicated linkage for eye color on 15q using comparative ratings of sibling pairs

scientific article published on 9 December 2005

Selective maternal seeding and environment shape the human gut microbiome.

scientific article published in March 2018

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Sequence variants in three loci influence monocyte counts and erythrocyte volume

scientific article published on 22 October 2009

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex differences in genetic architecture of complex phenotypes?

scientific article

Sex differences in heritability of BMI: a comparative study of results from twin studies in eight countries

scientific article published in October 2003

Sex differences in the human peripheral blood transcriptome

scientific article published on 17 January 2014

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.

scientific article

Short communication: Genetic association between schizophrenia and cannabis use.

scientific article published on 10 January 2017

Similarities in drinking behavior of twin's friends: moderation of heritability of alcohol use.

scientific article published on 27 December 2008

Sleep during a regular week night: a twin-sibling study

scientific article published in October 2008

Smoking During Adolescence as a Risk Factor for Attention Problems

scientific article published on 3 July 2014

Smoking status of parents, siblings and friends: predictors of regular smoking? Findings from a longitudinal twin-family study

scientific article

Socioeconomic status and hemodynamic recovery from mental stress.

scientific article published in March 2003

Socioeconomic status and stress-related biological responses over the working day.

scientific article published in May 2003

Spousal resemblance in psychopathology: A comparison of parents of children with and without psychopathology

scientific article

Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years

scientific article published on 4 September 2014

Stable genetic effects on symptoms of alcohol abuse and dependence from adolescence into early adulthood

scientific article published on 5 August 2011

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers

scientific article published on 4 December 2014

Stress responsivity and socioeconomic status: a mechanism for increased cardiovascular disease risk?

scientific article published in November 2002

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

scientific article published on 27 September 2012

Telomere length in circulating leukocytes is associated with lung function and disease.

scientific article published on 5 December 2013

Temporal stability of ambulatory stroke volume and cardiac output measured by impedance cardiography

scientific article published on 11 October 2005

Testing causality in the association between regular exercise and symptoms of anxiety and depression

scientific article

The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection

scientific article

The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

scientific article

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

scientific article published on 14 May 2013

The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium

scientific article published on December 2015

The Fagerström Test for Nicotine Dependence in a Dutch sample of daily smokers and ex-smokers

scientific article

The Genetic Overlap Between Hair and Eye Color

scientific article published on December 2016

The Genome of the Netherlands: design, and project goals

scientific article (publication date: February 2014)

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Netherlands Twin Register biobank: a resource for genetic epidemiological studies

scientific article published on June 2010

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects

scientific article published in June 2015

The association of alcohol intake with γ-glutamyl transferase (GGT) levels: evidence for correlated genetic effects

scientific article published on 27 September 2013

The association of current smoking behavior with the smoking behavior of parents, siblings, friends and spouses

scientific article published in July 2003

The association of mitochondrial content with prevalent and incident type 2 diabetes.

scientific article published on 11 February 2010

The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels

scientific article

The dopaminergic reward system and leisure time exercise behavior: a candidate allele study

scientific article published on 09 March 2014

The etiology of mathematical and reading (dis)ability covariation in a sample of Dutch twins.

scientific article published in December 2005

The five-factor model of personality and borderline personality disorder: a genetic analysis of comorbidity

scientific article published on 12 September 2009

The genetic architecture of body mass index from infancy to adulthood modified by parental education

scientific article published on 30 July 2016

The genetic architecture of liver enzyme levels: GGT, ALT and AST.

scientific article published on 12 April 2013

The genetic architecture of neuroticism in 3301 Dutch adolescent twins as a function of age and sex: a study from the Dutch twin register

scientific article published in February 2006

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

scientific article

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores

scientific article published on 14 September 2015

The heritability of HbA1c and fasting blood glucose in different measurement settings

scientific article published in December 2008

The heritability of beta cell function parameters in a mixed meal test design

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The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The influence of low job control on ambulatory blood pressure and perceived stress over the working day in men and women from the Whitehall II cohort

scientific article published in May 2004

The molecular genetic architecture of self-employment

scientific article

The relative contribution of genes and environment to alcohol use in early adolescents: are similar factors related to initiation of alcohol use and frequency of drinking?

scientific article published on 26 April 2008

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

The serotonin transporter gene length polymorphism (5-HTTLPR) and life events: no evidence for an interaction effect on neuroticism and anxious depressive symptoms

scientific article published on December 2010

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Thought problems from adolescence to adulthood: measurement invariance and longitudinal heritability

scientific article published on 18 June 2011

Trends in adolescent alcohol use: effects of age, sex and cohort on prevalence and heritability

scientific article published on 26 October 2011

Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project

scientific article published on April 2016

Twins, tissue, and time: an assessment of SNPs and CNVs

scientific article published on 28 September 2012

Underestimation of cardiac vagal control in regular exercisers by 24-hour heart rate variability recordings

scientific article

Using a multivariate model to assess the interactive effects of demographics and lifestyle on the hematological profile

scientific article published on 23 June 2017

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

scientific article

Variants in MTNR1B influence fasting glucose levels

scientific article

Variation in BMPR1B, TGFRB1 and BMPR2 and control of dizygotic twinning

scientific article published on October 2011

Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology

scientific article published on 12 April 2010

Vitamin D receptor gene polymorphisms have negligible effect on human height

scientific article published in October 2008

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project

scientific article