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List of works by Gregg Duester

A regulatory network controls nephrocan expression and midgut patterning

scientific journal article

ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function

scientific article published on September 1, 1998

ADH4-lacZ Transgenic Mouse Reveals Alcohol Dehydrogenase Localization in Embryonic Midbrain/Hindbrain, Otic Vesicles, and Mesencephalic, Trigeminal, Facial, and Olfactory Neural Crest

scientific article published on October 1, 1998

Adh1 and Adh1/4 knockout mice as possible rodent models for presymptomatic Parkinson's disease

scientific article published on 6 November 2011

Alcohol Dehydrogenase as a Critical Mediator of Retinoic Acid Synthesis from Vitamin A in the Mouse Embryo ,

scientific article published on February 1, 1998

Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice

scientific article published on 9 May 2014

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems

scientific journal article

An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment

scholarly article by Nianwei Lin published in March 2014

Antagonism between retinoic acid and fibroblast growth factor signaling during limb development

scientific article published on 25 April 2013

Characterization of the functional gene encoding mouse class III alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) and an unexpressed processed pseudogene with an intact open reading frame

scientific article published on April 1996

Class I and class IV alcohol dehydrogenase (retinol dehydrogenase) gene expression in mouse embryos

scientific article published on January 1995

Concerted action of aldehyde dehydrogenases influences depot-specific fat formation.

scientific article

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid

scientific article

DNA elements mediating retinoid and thyroid hormone regulation of alcohol dehydrogenase gene expression

scientific article published on January 1993

Diet-Induced Visceral Obesity in Female Mice Depends on Autocrine Retinoic Acid Production

Discovery of genes required for body axis and limb formation by global identification of retinoic acid-regulated epigenetic marks

scientific article published on 18 May 2020

Distal and proximal cis-linked sequences are needed for the total expression phenotype of the mouse alcohol dehydrogenase 1 (Adh1) gene

scientific article published in May 2002

Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

scientific article

Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain

scientific article (publication date: March 2003)

Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome

scientific journal article

Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors

scientific article published on 28 October 2016

Effect of retinoic acid signaling on Wnt/beta-catenin and FGF signaling during body axis extension

scientific article published on 17 June 2009

Endogenous retinoic acid signaling is required for maintenance and regeneration of cornea

scientific article published on 10 November 2016

Enzymatic characterization of recombinant mouse retinal dehydrogenase type 1.

scientific article published in May 2003

Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome

scientific article published in July 1996

Evidence that class IV alcohol dehydrogenase may function in embryonic retinoic acid synthesis

scientific article published on January 1997

Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3

scientific journal article

Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract

scientific article

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid

scientific article

Function of alcohol dehydrogenase and aldehyde dehydrogenase gene families in retinoid signaling

scientific article

Functional significance of aldehyde dehydrogenase ALDH1A1 to the nigrostriatal dopamine system

scientific article published on 26 June 2011

Fusion of the Escherichia coli tRNALeu1 promoter to the galK gene: analysis of sequences necessary for growth-rate-dependent regulation.

scientific article published in October 1982

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid

scientific journal article

Genomic Knockout of Two Presumed Forelimb Tbx5 Enhancers Reveals They Are Nonessential for Limb Development.

scientific article

Genomic structure and expression of the ADH7 gene encoding human class IV alcohol dehydrogenase, the form most efficient for retinol metabolism in vitro.

scientific article

Human Liver Alcohol Dehydrogenase Gene Expression

article

Id genes are essential for early heart formation

scientific article published on 9 August 2017

Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).

scientific article published on 24 November 2006

Impaired retinol utilization in Adh4 alcohol dehydrogenase mutant mice

scientific journal article

In vivo contribution of Class III alcohol dehydrogenase (ADH3) to alcohol metabolism through activation by cytoplasmic solution hydrophobicity

scientific article published on 4 January 2006

Intron-dependent evolution of the nucleotide-binding domains within alcohol dehydrogenase and related enzymes

scientific article

Investigation of retinoic acid function during embryonic brain development using retinaldehyde-rescued Rdh10 knockout mice

scientific article published on 22 July 2013

Involvement of Alcohol-Metabolizing Enzymes in Retinoic Acid Synthesis and Inhibition by Ethanol

Keeping an eye on retinoic acid signaling during eye development

scientific article published on 11 September 2008

Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates

scientific article published in April 2002

Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenase

scientific article

Knocking Out Enhancers to Enhance Epigenetic Research

scientific article published on 19 November 2018

Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis

scientific journal article

Mechanisms of retinoic acid signalling and its roles in organ and limb development

scientific article

Medium- and short-chain dehydrogenase/reductase gene and protein families : Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism

scientific article published on December 2008

Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid

scientific article (publication date: 11 June 1999)

Modeling Parkinson's disease genetics: Altered function of the dopamine system in Adh4 knockout mice

article

Molecular analysis of two closely related mouse aldehyde dehydrogenase genes: identification of a role for Aldh1, but not Aldh-pb, in the biosynthesis of retinoic acid

scientific journal article

Molecular cloning and characterization of a cDNA for the beta subunit of human alcohol dehydrogenase

scientific article

Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis

scientific article

Molecular genetic analysis of human alcohol dehydrogenase

scientific article published on 01 January 1985

Mouse but not zebrafish requires retinoic acid for control of neuromesodermal progenitors and body axis extension

Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice

scientific article

Multiple mRNAs for human alcohol dehydrogenase (ADH): developmental and tissue specific differences

scientific article

N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications.

scientific article published on 15 January 2018

NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling

scientific article

Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling

scientific article

Non-cell-autonomous retinoid signaling is crucial for renal development

scientific article

Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis

scientific article published on 6 August 2016

Nucleotide sequence of an Escherichia coli tRNA (Leu 1) operon and identification of the transcription promoter signal

scientific article published on May 1981

Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation

scientific journal article

Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes

scientific article

Patterning of forelimb bud myogenic precursor cells requires retinoic acid signaling initiated by Raldh2

scientific journal article

Publisher Correction: N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

scholarly article published in Nature Neuroscience

RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development.

scientific article published in October 2000

Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation

scientific journal article

Rdh10 mutants deficient in limb field retinoic acid signaling exhibit normal limb patterning but display interdigital webbing

scientific article

Regional Restriction of Alcohol/Retinol Dehydrogenases along the Mouse Gastrointestinal Epithelium

scientific article published on November 1, 1997

Requirement of mesodermal retinoic acid generated by Raldh2 for posterior neural transformation

scientific journal article

Resolving molecular events in the regulation of meiosis in male and female germ cells

scientific article published on 13 August 2013

Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function

scientific article

Retinaldehyde represses adipogenesis and diet-induced obesity.

scientific article

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

scientific article published on 14 September 2015

Retinoic Acid Signaling and Neural Patterning

Retinoic Acid Signaling and Neural Patterning☆

Retinoic acid biosynthetic enzyme ALDH1 localizes in a subset of retinoid-dependent tissues duringXenopus development

article

Retinoic acid controls body axis extension by directly repressing Fgf8 transcription

scientific article

Retinoic acid controls expression of tissue remodeling genes Hmgn1 and Fgf18 at the digit-interdigit junction

scientific journal article

Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway

scientific article published on June 2008

Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations

scientific article published on 02 January 2020

Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia

scientific article

Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development

scientific journal article

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

scientific journal article

Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex

scientific article published on 11 October 2011

Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning

scientific article

Retinoic acid regulation of the somitogenesis clock

scientific article

Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinoic acid synthesis

scientific article published on March 1991

Retinoic acid signaling in perioptic mesenchyme represses Wnt signaling via induction of Pitx2 and Dkk2

scientific article

Retinoic acid signaling pathways

scientific article published on 04 July 2019

Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2.

scientific article

Retinoic acid synthesis and signaling during early organogenesis

scientific article

Retinoic acid synthesis controlled by Raldh2 is required early for limb bud initiation and then later as a proximodistal signal during apical ectodermal ridge formation

scientific journal article

Retinoic acid synthesis in the prevertebrate amphioxus involves retinol oxidation

scientific article published on 13 July 2002

Retinoic acid's reproducible future

scientific article published in December 2017

Retinoic acid-independent expression of Meis2 during autopod patterning in the developing bat and mouse limb

scientific article

Retinoic-acid signalling in node ectoderm and posterior neural plate directs left-right patterning of somitic mesoderm

scientific article

Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis

scientific article

Retinoid signaling in control of progenitor cell differentiation during mouse development

scientific article published on 21 August 2013

Retinoids and the alcohol dehydrogenase gene family

scientific article

Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase

scientific article published on 17 April 2002

Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone

scientific journal article

Sex-specific timing of meiotic initiation is regulated by Cyp26b1 independent of retinoic acid signalling

scientific article

Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression

scientific journal article

SnapShot: retinoic acid signaling

scientific article

Stimulation of premature retinoic acid synthesis in Xenopus embryos following premature expression of aldehyde dehydrogenase ALDH1.

scientific article published in February 1999

Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3

scientific article

Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina

scientific journal article

Temporal expression of the human alcohol dehydrogenase gene family during liver development correlates with differential promoter activation by hepatocyte nuclear factor 1

scientific article

The Role of Retinoic Acid in Limb Development

article

The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration

scientific article published on 17 April 2019

The Xenopus alcohol dehydrogenase gene family: characterization and comparative analysis incorporating amphibian and reptilian genomes

scientific article

The distal end of the ribosomal RNA operon rrnD of Eschenchia coli contains a tRNA1thrgene, two 5S rRNA genes and a transcription terminator

scientific article published on September 11, 1980

The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina

scientific article published in May 2004

Tissue expression pattern of class II and class V genes found in the Adh complex on mouse chromosome 3.

scientific article

Towards a Better Vision of Retinoic Acid Signaling during Eye Development

scientific article published on 19 January 2022

Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma

scientific article

Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension

scientific article published on 24 August 2011

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis

scientific journal article

Wnt8a and Wnt3a cooperate in the axial stem cell niche to promote mammalian body axis extension

scientific article published on 23 April 2015

trans activation of human alcohol dehydrogenase gene expression in hepatoma cells by C/EBP molecules bound in a novel arrangement just 5' and 3' to the TATA box.

scientific article published on September 1990