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List of works by Philipp Khaitovich

A genome-wide comparison of recent chimpanzee and human segmental duplications

scientific article

A neutral model of transcriptome evolution

scientific article

Ab initio identification of transcription start sites in the Rhesus macaque genome by histone modification and RNA-Seq ⬇️

scientific article published on October 14, 2010

Accelerated aging-related transcriptome changes in the female prefrontal cortex

scientific article (publication date: October 2012)

Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies

scientific article published on 01 April 2020

Aging and gene expression in the primate brain

scientific article published in September 2005

Birth and expression evolution of mammalian microRNA genes.

scientific article

Changes in Lipidome Composition during Brain Development in Humans, Chimpanzees, and Macaque Monkeys

scientific article

Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain

scientific article published on 28 February 2016

Comparison of protein and mRNA expression evolution in humans and chimpanzees

scientific article

Comprehensive survey of human brain microRNA by deep sequencing

scientific article

Comprehensive transcriptome analysis of neocortical layers in humans, chimpanzees and macaques

scientific article published on 17 April 2017

Conservation, evolution, and regulation of splicing during prefrontal cortex development in humans, chimpanzees and macaques.

scientific article

Conserved expression of lincRNA during human and macaque prefrontal cortex development and maturation

scientific article

Constrained vertebrate evolution by pleiotropic genes

article

De novo identification and quantification of single amino-acid variants in human brain.

scientific article published on 9 July 2014

Deep sequencing reveals a novel class of bidirectional promoters associated with neuronal genes

scientific article

Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series

scientific article

Differences in lipidome and metabolome organization of prefrontal cortex among human populations

scientific article published on 04 December 2019

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism

scientific article

Estimating accuracy of RNA-Seq and microarrays with proteomics

scientific article

Evaluating intra- and inter-individual variation in the human placental transcriptome

scientific article published on 19 March 2015

Evolution of human longevity uncoupled from caloric restriction mechanisms

scientific article (publication date: 2014)

Evolution of neuronal and endothelial transcriptomes in primates

scientific article published on 12 July 2010

Evolution of primate gene expression

scientific article published on September 2006

Evolution of the human-specific microRNA miR-941.

scientific article

Evolutionary and ontogenetic changes in RNA editing in human, chimpanzee, and macaque brains

scientific article published on 23 October 2013

Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness

scientific article (publication date: May 2014)

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

scientific article (publication date: April 2012)

FUNC: a package for detecting significant associations between gene sets and ontological annotations

scientific article published on 6 February 2007

Fast mapping of short sequences with mismatches, insertions and deletions using index structures

scientific article

Fluoxetine Treatment Rescues Energy Metabolism Pathway Alterations in a Posttraumatic Stress Disorder Mouse Model

scientific article published on 30 April 2016

Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder

scientific article published on 8 February 2016

Functional analysis of human and chimpanzee promoters

scientific article

Functionality of intergenic transcription: an evolutionary comparison

scientific article published on 28 August 2006

Gene expression across mammalian organ development

scientific article published on 26 June 2019

Gene expression becomes heterogeneous with age

scientific article published on 01 May 2006

Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity

scientific article

Genetic Characterization of Russian Rapeseed Collection and Association Mapping of Novel Loci Affecting Glucosinolate Content

scientific article published on 12 August 2020

Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel

scientific article

Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway ⬇️

scientific article published on August 3, 2011

Human and chimpanzee gene expression differences replicated in mice fed different diets

scientific article

Human brain evolution: transcripts, metabolites and their regulators

scientific article

Human-specific features of spatial gene expression and regulation in eight brain regions

scientific article published on 13 June 2018

Identification of Immediate Early Genes in the Nervous System of Snail Helix lucorum

scientific article published on 21 May 2019

Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex

scientific article published on October 2008

Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq

scientific article

Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans

scientific article

Lipidome Evolution in Mammalian Tissues

scientific article published on 01 August 2018

Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders

scientific article published on 08 August 2018

Lipidome analysis of milk composition in humans, monkeys, bovids, and pigs

scientific article published on 19 June 2020

Lipidome determinants of maximal lifespan in mammals

scientific article

Long-Term Fluoxetine Administration Causes Substantial Lipidome Alteration of the Juvenile Macaque Brain ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content.

scientific article

Metabolic changes in schizophrenia and human brain evolution

scientific article published on 05 August 2008

Metabolome signature of autism in the human prefrontal cortex

scientific article published on 21 June 2019

Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development

scientific article published on 26 April 2016

MicroRNA expression and regulation in human, chimpanzee, and macaque brains

scientific article

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain

scientific article

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates

scientific article

Molecular footprint of Medawar's mutation accumulation process in mammalian aging

scientific article published on 06 May 2019

Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans

scientific article published on April 2014

Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues

scientific article

Organoid single-cell genomic atlas uncovers human-specific features of brain development

scientific article published on 16 October 2019

Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees

scientific article

Positive selection on gene expression in the human brain

scientific article

Predominant Patterns of Splicing Evolution on Human, Chimpanzee, and Macaque Evolutionary Lineages

scientific article published on 14 February 2018

Publisher Correction: Lipidome determinants of maximal lifespan in mammals

scholarly article published in Scientific Reports

Rapid metabolic evolution in human prefrontal cortex

scientific article (publication date: 12 April 2011)

Recently Evolved Tumor Suppressor Transcript TP73-AS1 Functions as Sponge of Human-Specific miR-941.

scientific article

Regional patterns of gene expression in human and chimpanzee brains

scientific article

Sequence features associated with microRNA strand selection in humans and flies

scientific article

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains

scientific article published on 18 May 2020

Spatial proximity and similarity of the epigenetic state of genome domains.

scientific article

Stress‐associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain ⬇️

scientific article published on October 18, 2012

Structure-Preserving and Perceptually Consistent Approach for Visualization of Mass Spectrometry Imaging Datasets

scientific article published on 29 December 2020

Systematic analysis of gene expression in human brains before and after death

scientific article

The effects of probe binding affinity differences on gene expression measurements and how to deal with them

scientific article

The evolution of gene expression levels in mammalian organs

scientific article (publication date: 19 October 2011)

Toward a neutral evolutionary model of gene expression

scientific article published on 16 April 2005

Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging.

scientific article

Transcriptional neoteny in the human brain

scientific article (publication date: 7 April 2009)

Ultra-performance liquid chromatography-mass spectrometry for precise fatty acid profiling of oilseed crops

scientific article published on 06 March 2019

Widespread expression of piRNA-like molecules in somatic tissues

scientific article

Widespread splicing changes in human brain development and aging

scientific article published on January 2013

codes for a mitochondrial peptide linking respiration and lipid metabolism

scientific article published on 22 February 2019

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