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List of works by Toshikazu Yoshikawa

15th anniversary of rebamipide: looking ahead to the new mechanisms and new applications

scientific article

7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by increasing the production of reactive oxygen species

scientific article

A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice

scientific article

A PPAR-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats

scientific article published on January 2004

A case of advanced gastric cancer with bone metastases and DIC responding to oral administration of TS-1

scientific article

A case of advanced gastric cancer with pulmonary carcinomatous lymphangitis responding remarkably to combination chemotherapy of docetaxel, CDDP and S-1

scientific article

A case of inoperable duodenal cancer achieving long-term survival after multidisciplinary treatment

scientific article

A case of lupus peritonitis and cystitis after ovulation induction therapy

scientific article published on September 1, 2003

A case of phlegmonous esophagogastritis improved with conservative therapy

scientific article published in December 2005

A case of probable autoimmune hepatitis from which the persistence of hepatitis A IgM antibody, and the improvement was pathologically obtained by ursodeoxycholic acid medication

scientific article

A case of successful treatment of disseminated herpes simplex virus infection with acyclovir on the basis of early diagnosis by esophageal biopsy

scientific article published in November 2005

A case report--locally advanced pancreatic adenocarcinoma was resected after chemotherapy

scientific article published on November 2010

A comparative study on endoscopic ulcer healing of omeprazole versus rabeprazole with respect to CYP2C19 genotypic differences

scientific article published in September 2005

A multicenter, randomized, double-blind, placebo-controlled trial of high-dose rebamipide treatment for low-dose aspirin-induced moderate-to-severe small intestinal damage

scientific article

A novel amplification target, ARHGAP5, promotes cell spreading and migration by negatively regulating RhoA in Huh-7 hepatocellular carcinoma cells

scientific article

A novel potent inhibitor of inducible nitric oxide inhibitor, ONO-1714, reduces intestinal ischemia-reperfusion injury in rats

scientific article

A novel potent inhibitor of inducible nitric oxide synthase, ONO-1714, reduces hyperoxic lung injury in mice

scientific article published on 18 September 2006

A novel vitamin E derivative (TMG) protects against gastric mucosal damage induced by ischemia and reperfusion in rats

scientific article published in January 2003

A novel water-soluble vitamin E derivative prevents acute lung injury by bacterial endotoxin

scientific article published in April 2004

A novel water-soluble vitamin E derivative protects against aspirin-induced gastric mucosal injury in rats

scientific article (publication date: December 2005)

A novel water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol, protects against acute lung injury and mortality in endotoxemic rats

scientific article published in December 2002

A pilot study to evaluate a new combination therapy for gastric ulcer: Helicobacter pylori eradication therapy followed by gastroprotective treatment with rebamipide

scientific article published on January 2006

A randomized, double-blind, sham-controlled study of static electric field therapy by high voltage alternating current for active rheumatoid arthritis

scientific article published on 19 April 2013

A specific peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand, pioglitazone, ameliorates gastric mucosal damage induced by ischemia and reperfusion in rats

scientific article published on January 2002

Aberrant expression of the PHF14 gene in biliary tract cancer cells

scientific article published on 29 March 2013

Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats

scientific article published on 04 April 2007

Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents

scientific article

Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans

scientific article

Acetyl salicylic acid induces damage to intestinal epithelial cells by oxidation-related modifications of ZO-1.

scientific article published on 23 August 2012

Acute exercise increases fibroblast growth factor 21 in metabolic organs and circulation

scientific article published on June 2016

Adenoendocrine cell carcinoma of the gallbladder clinically mimicking squamous cell carcinoma.

scientific article published on 24 April 2009

Adiponectin gene polymorphism (G276T) is not associated with incipient diabetic nephropathy in Japanese type 2 diabetic patients

scientific article published in September 2004

Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer

scientific article published on September 2008

Adoptive cellular therapy enhances the helper T cell response and reduces the number of regulatory T cells

scientific article

Air pollution and pulmonary diseases

scientific article published on 01 August 2005

Alpha-tocopherol prevents apoptosis of vascular endothelial cells via a mechanism exceeding that of mere antioxidation

scientific article

Alteration of the expression profiles of acidic mucin, sialytransferase, and sulfotransferases in the intestinal epithelium of rats infected with the nematode Nippostrongylus brasiliensis

scientific article published on 21 August 2008

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma

scientific article

An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity

scientific article

An endogenous metabolite of dopamine, 3,4-dihydroxyphenylethanol, acts as a unique cytoprotective agent against oxidative stress-induced injury

scientific article published in March 2004

Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

scientific article published on 25 November 2008

Angiotensinogen gene polymorphism (Met235Thr) influences visceral obesity and insulin resistance in obese Japanese women.

scientific article published in June 2006

Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines

scientific article published on July 2004

Anoxia/reoxygenation induces epithelial-mesenchymal transition in human colon cancer cell lines

scientific article published on 10 April 2013

Anoxia/reoxygenation-induced leukocyte-endothelial cell interactions

scientific article

Anti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanism

scientific article published in January 2004

Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis

scientific article published on 01 August 2006

Antioxidant action of fermented grain food supplement: Scavenging of peroxyl radicals and inhibition of plasma lipid oxidation induced by multiple oxidants

scientific article published on 31 May 2017

Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.

scientific article published in December 2005

Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice.

scientific article published on March 2009

Antitumor effect of whole body hyperthermia with alpha-galactosylceramide in a subcutaneous tumor model of colon cancer.

scientific article published on November 2007

Aplastic anemia evolving into overt myelodysplastic syndrome/acute myeloid leukemia with t(3;5)(p25;q31)

scientific article published on 01 September 2002

Assessment of cerebral blood flow in patients with multiple chemical sensitivity using near-infrared spectroscopy--recovery after olfactory stimulation: a case-control study

scientific article published on 15 February 2015

Assessment of radical scavenging capacity of antioxidants contained in foods and beverages in plasma solution

scientific article published in May 2015

Association between capacity of interferon-alpha production and metabolic parameters

scientific article published in June 2010

Association between cardiovascular autonomic neuropathy and left ventricular hypertrophy in diabetic haemodialysis patients

scientific article published on 13 July 2004

Association between elevated testosterone and development of microalbuminuria during puberty in female subjects with type 1 diabetes: response to Amin et Al.

scientific article published in October 2003

Association between plasma sLOX-1 concentration and arterial stiffness in middle-aged and older individuals

scientific article

Association between serum bioavailable testosterone concentration and the ratio of glycated albumin to glycated hemoglobin in men with type 2 diabetes.

scientific article published on 26 November 2007

Association between serum estradiol concentrations and carotid atherosclerosis in men with type 2 diabetes mellitus

scientific article

Association between serum testosterone concentration and carotid atherosclerosis in men with type 2 diabetes

scientific article published in June 2003

Association between serum testosterone concentration and collagen degradation fragments in men with type 2 diabetes mellitus

scientific article published on 01 September 2007

Association between urinary albumin excretion and plasma 5-hydroxyindole-3-acetic acid concentration in men with type 2 diabetes

scientific article published on 10 July 2007

Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentration in male patients with type 2 diabetes: a possible link between urinary albumin excretion and cardiovascular disease

scientific article published in December 2004

Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentrations in women with type 2 diabetes

scientific article published on 15 March 2007

Association of HLA class I and class II alleles with susceptibility to endometriosis

scientific article published on 01 November 2002

Association of Odor Thresholds and Responses in Cerebral Blood Flow of the Prefrontal Area during Olfactory Stimulation in Patients with Multiple Chemical Sensitivity

scientific article

Association of single-nucleotide polymorphisms in the suppressor of cytokine signaling 2 (SOCS2) gene with type 2 diabetes in the Japanese

scientific article published on 10 January 2006

Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women

scientific article published on 01 April 2002

Association study of G1704T and G82S polymorphisms of RAGE gene for microalbuminuria in Japanese type 2 diabetic patients

scientific article published on 01 April 2005

Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification

scientific article

Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice

scientific article published in February 2003

Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice

scientific article published in January 2002

Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling

scientific article published on April 2008

Atrophic gastritis is associated with coronary artery disease

scientific article

Augmentation of central arterial pressure as a marker of atherosclerosis in patients with type 2 diabetes

scientific article published on 01 February 2003

Azelnidipine, a new calcium channel blocker, inhibits endothelial inflammatory response by reducing intracellular levels of reactive oxygen species.

scientific article

BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice

scientific article published on 01 March 2013

Basic and translational research on proteinase-activated receptors: implication of proteinase/proteinase-activated receptor in gastrointestinal inflammation

scientific article published on December 2008

Beta2-adrenergic receptor polymorphism and obesity in type 2 diabetes: response to van Tilburg et al.

scientific article published in May 2003

Bleeding from major and minor duodenal papillae due to hemosuccus pancreaticus confirmed with side-view gastroduodenal endoscopy.

scientific article published in December 2011

Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

scientific article published on 5 April 2010

Blocking of NF-kappaB activation enhances the tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line.

scientific article published in April 2003

Bofutsushosan, an Oriental Herbal Medicine, Attenuates the Weight Gain of White Adipose Tissue and the Increased Size of Adipocytes Associated with the Increase in Their Expression of Uncoupling Protein 1 in High-Fat Diet-Fed Male KK/Ta mice

scientific article

Bone mass and bone resorption in postmenopausal women with type 2 diabetes mellitus.

scientific article published in July 2008

Bone stiffness in men with type 2 diabetes mellitus

scientific article published in December 2008

Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development.

scientific article published on 26 August 2016

CV-11974, angiotensin II type I receptor antagonist, protects against ischemia-reperfusion injury of the small intestine in rats

scientific article published on 20 March 2006

CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis

scientific article published on 01 September 2007

CYP3A induction aggravates endotoxemic liver injury via reactive oxygen species in male rats

scientific article published in September 2004

CagA protein of Helicobacter pylori: a hijacker of gastric epithelial cell signaling.

scientific article published on 27 October 2006

Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts.

scientific article

Carbon monoxide liberated from CO-releasing molecule (CORM-2) attenuates ischemia/reperfusion (I/R)-induced inflammation in the small intestine

scientific article published in April 2010

Carbon monoxide promotes gastric wound healing in mice via the protein kinase C pathway

scientific article

Changes in cerebral blood flow during olfactory stimulation in patients with multiple chemical sensitivity: a multi-channel near-infrared spectroscopic study

scientific article (publication date: 2013)

Chemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation

scientific article

Chronic oxidative stress causes amplification and overexpression of ptprz1 protein tyrosine phosphatase to activate beta-catenin pathway

scientific article

Clinical and genetic characteristics of diabetic patients with high-titer (>10,000 U/ml) of antibodies to glutamic acid decarboxylase.

scientific article

Clinical and genetic heterogeneity of latent autoimmune diabetes in adults.

scientific article published in July 2003

Clinical heterogeneity of patients with adult-onset diabetes and GAD autoantibodies

scientific article published on 01 December 2002

Coffee consumption and risk of type 2 diabetes mellitus

scientific article

Colonic insufflation with carbon monoxide gas inhibits the development of intestinal inflammation in rats

scientific article

Combination therapy with rituximab and cladribine for patients with follicular lymphoma

scientific article

Comments on the common cold

scientific article published on 01 March 2003

Comparison of human herpes virus 8 related primary effusion lymphoma with human herpes virus 8 unrelated primary effusion lymphoma-like lymphoma on the basis of HIV: report of 2 cases and review of 212 cases in the literature

scientific article published on 29 November 2006

Complementary DNA microarray analysis in acute lung injury induced by lipopolysaccharide and diesel exhaust particles.

scholarly article

Components of diesel exhaust particles differentially affect lung expression of cyclooxygenase-2 related to bacterial endotoxin

scientific article published in November 2004

Comprehensive cytogenetic study by spectral karyotyping on blastic natural killer cell leukemia/lymphoma

scientific article published on 01 March 2002

Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats

scientific article

Cytoprotection by interleukin-6 against liver injury induced by lipopolysaccharide

scientific article published on 01 February 2005

Cytotoxic T lymphocyte-associated antigen 4 inhibition increases the antitumor activity of adoptive T-cell therapy when carried out with naïve rather than differentiated T cells.

scientific article

Daikenchuto, a Kampo medicine, regulates intestinal fibrosis associated with decreasing expression of heat shock protein 47 and collagen content in a rat colitis model

scientific article published in January 2011

Defense mechanism of the esophageal mucosa and esophageal inflammation

scientific article published on March 1, 2003

Detection of N-(hexanoyl)lysine in the tropomyosin 1 protein in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric cancer cells.

scientific article

Di-(2-ethylhexyl) phthalate enhances atopic dermatitis-like skin lesions in mice

scientific article

Dichotomous effect of ultraviolet B on the expression of corneodesmosomal enzymes in human epidermal keratinocytes.

scientific article

Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and intercellular adhesion molecule-1.

scientific article published in May 2002

Dietary exercise as a novel strategy for the prevention and treatment of metabolic syndrome: effects on skeletal muscle function

scientific article

Dietary whey hydrolysate with exercise alters the plasma protein profile: a comprehensive protein analysis

scientific article

Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice

scientific article published on January 2003

Different remodelling against left ventricular overload between diabetic and non‐diabetic haemodialysis patients

scientific article published on 01 October 2003

Differential regulation of intracellular redox state by extracellular matrix proteins in glomerular mesangial cells: potential role in diabetic nephropathy

scientific article published on 01 January 2006

Discrepancies between clinical and autopsy diagnoses in cases of malignant neoplasm

scientific article published on 01 January 2002

Dual role of nitric oxide in gastric hypersecretion in the distended stomach: inhibition of acid secretion and stimulation of pepsinongen secretion

scientific article

ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry

scientific article

Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice

scientific article published on 19 February 2010

Ecabet sodium promotes the healing of trinitrobenzene-sulfonic-acid-induced ulceration by enhanced restitution of intestinal epithelial cells.

scientific article published on July 2010

Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats

scientific article

Effect of +36T>C in intron 1 on the glutamine: fructose-6-phosphate amidotransferase 1 gene and its contribution to type 2 diabetes in different populations

scientific article published on 26 September 2006

Effect of 15-deoxy-delta 12,14-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice

scientific article published in November 2003

Effect of Helicobacter pylori-mediated inflammation on nonsteroidal anti-inflammatory drugs-induced gastric mucosal injury

scientific article (publication date: December 2002)

Effect of a novel water-soluble vitamin E derivative as a cure for TNBS-induced colitis in rats

scientific article published on March 2006

Effect of atorvastatin on in vitro expression of resistin in adipocytes and monocytes/macrophages and effect of atorvastatin treatment on serum resistin levels in patients with type 2 diabetes

scientific article published on 14 October 2005

Effect of clinical pathway in the treatment of inpatients with ischemic colitis

scientific article published in March 2007

Effect of exercise on hepatic gene expression in rats: a microarray analysis

scientific article

Effect of hyperthermia combined with gemcitabine on apoptotic cell death in cultured human pancreatic cancer cell lines

scientific article

Effect of ultrasonic stimulation on mRNA abundance of uncoupling protein (UCP) 2 and UCP 3 in gastrocnemius muscle of rats

scientific article published in January 2005

Effects of 15-deoxy-Delta12,14-prostaglandin J2 on the expression of Toll-like receptor 4 and 2 in the murine lung in the presence of lipopolysaccharide

scientific article published on 01 March 2005

Effects of 15-deoxy-delta(12,14)-prostaglandin J2 on nuclear localization of GATA-3 in the murine lung in the presence of lipopolysaccharide.

scientific article published in January 2005

Effects of 15-deoxy-delta12,14-prostaglandin J2 on the cyclooxygenase-2 expression in the murine lung in the presence of lipopolysaccharide.

scientific article

Effects of Helicobacter pylori water extract on expression of endothelial adhesion molecules

scientific article published in June 2004

Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice

scientific article

Effects of anticancer agents on cell viability, proliferative activity and cytokine production of peripheral blood mononuclear cells

scientific article published on 20 November 2012

Effects of caffeine on the uncoupling protein family in obese yellow KK mice

scientific article

Effects of components derived from diesel exhaust particles on lung physiology related to antigen

scientific article published in January 2007

Effects of diesel exhaust on lung inflammation related to bacterial endotoxin in mice.

scientific article published in November 2006

Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th immunity in mice.

scientific article published on 8 December 2008

Effects of diesel exhaust particles on cytokine production by splenocytes stimulated with lipopolysaccharide

scientific article published on 01 January 2007

Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice

scientific article published on 2 June 2007

Effects of nano particles on antigen-related airway inflammation in mice

scientific article

Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide

scientific article

Effects of tumor necrosis factor-alpha inhibitors on lung lesions with rheumatoid arthritis

scientific article published on 01 July 2003

Effects of volatile constituents of a rosemary extract on allergic airway inflammation related to house dust mite allergen in mice.

scientific article published in August 2005

Effects of volatile constituents of rosemary extract on lung inflammation induced by diesel exhaust particles

scientific article published on 01 July 2006

Efficacy of glimepiride in patients with poorly controlled insulin-treated type 2 diabetes mellitus.

scientific article published in October 2005

Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease

scientific article published on 24 July 2010

Efficacy of magnifying endoscopy with flexible spectral imaging color enhancement in the diagnosis of colorectal tumors.

scientific article published in January 2011

Efficient direct conversion of human fibroblasts into myogenic lineage induced by co-transduction with MYCL and MYOD1.

scientific article published on 10 May 2017

Endoscopic analysis of gastric ulcer after one week's treatment with omeprazole and rabeprazole in relation to CYP2C19 genotype

scientific article published on 13 October 2007

Endoscopic diagnosis of small intestinal diseases.

scientific article

Endoscopic injection sclerotherapy with ethanolamine oleate with iopamidol for esophagojejunal varices in idiopathic portal hypertension

scientific article published on 20 September 2008

Endoscopic mucosal resection with 0.13% hyaluronic acid solution for colorectal polyps less than 20 mm: a randomized controlled trial

scientific article published in August 2012

Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice

scientific article published in May 2003

Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with oral eicosapentaenoic acid

scientific article published in November 2002

Enzyme-linked immunosorbent assay for circulating human resistin: resistin concentrations in normal subjects and patients with type 2 diabetes

scientific article

Epigenetic silencing of RELN in gastric cancer.

scientific article

Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma

scientific article published on 30 November 2012

Exercise and functional foods

scientific article

Expression of inducible nitric oxide synthase and nitric oxide-modified proteins in Helicobacter pylori-associated atrophic gastric mucosa

scientific article

Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans.

scientific article

FGF19 protects colonic epithelial cells against hydrogen peroxide.

scientific article

Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone in patients with cancer pain

scientific article

Fermented grain products, production, properties and benefits to health

scientific article published on 01 September 2003

Gastric peroxisome proliferator activator receptor-γ expression and cytoprotective actions of its ligands against ischemia-reperfusion injury in rats

scientific article

Gastrointestinal Cytoprotection by PPAR Ligands

scientific article published on September 21, 2010

Gene expression analysis following hypoxia-reoxygenation in rat gastric epithelial cells using a high-density oligonucleotide array.

scientific article published on January 2004

Gene expression analysis of murine lungs following pulmonary exposure to Asian sand dust particles

scientific article published on September 2007

Gene expression profile of isolated rat adipocytes treated with anthocyanins

scientific article published on 12 January 2005

Gene expression profiles on hypoxia and reoxygenation in rat gastric epithelial cells: a high-density DNA microarray analysis

scientific article published on 20 June 2006

Gene therapy for colon cancer targeting NF-kappa B

scientific article published on 01 September 2003

Generation of reactive oxygen species in sperms of rats as an earlier marker for evaluating the toxicity of endocrine-disrupting chemicals

scientific article published on September 6, 2010

Genetic contribution of the interleukin-10 promoter polymorphism in endometriosis susceptibility

scientific article published on 01 January 2002

Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility

scientific article published in May 2004

Glimepiride and serum adiponectin level in type 2 diabetic subjects: response to Nagasaka et al.

scientific article published in December 2003

Global analysis of gene expression in gastric ischemia-reperfusion: a future therapeutic direction for mucosal protective drugs

scientific article

Glycyrrhizin and Serum Testosterone Concentrations in Male Patients With Type 2 Diabetes

scientific article published on October 1, 2003

Heat shock protein 70-dependent protective effect of polaprezinc on acetylsalicylic acid-induced apoptosis of rat intestinal epithelial cells.

scientific article published on 17 June 2011

Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestinal cancer.

scientific article

Heat-shock protein 70-overexpressing gastric epithelial cells are resistant to indomethacin-induced apoptosis

scientific article

Helicobacter pylori activates gastric epithelial cells to produce interleukin-8 via protease-activated receptor 2.

scientific article published on January 2007

Helicobacter pylori infection and arterial stiffness in patients with type 2 diabetes mellitus

scientific article published on December 2008

Helicobacter pylori isolated from a patient with Ménétrier's disease increases hepatocyte growth factor mRNA expression in gastric fibroblasts: comparison with Helicobacter pylori isolated from other gastric diseases

scientific article published on 08 November 2007

Helicobacter pylori: a ROS-inducing bacterial species in the stomach.

scientific article published on 05 September 2010

Heme oxygenase-1: a novel therapeutic target for gastrointestinal diseases

scientific article published on 26 February 2011

Hemopexin is upregulated in rat intestinal mucosa injured by indomethacin.

scientific article

Hepatic senescence marker protein-30 is involved in the progression of nonalcoholic fatty liver disease

scientific article published on 28 November 2009

Hepatic steatosis in chronic hepatitis C patients infected with genotype 2 is associated with insulin resistance, hepatic fibrosis and affects cumulative positivity of serum hepatitis C virus RNA in peginterferon and ribavirin combination therapy

scientific article published on 26 September 2011

Hepatitis C virus and atherosclerosis in patients with type 2 diabetes

scientific article published in March 2003

High expression of p300 in HCC predicts shortened overall survival in association with enhanced epithelial mesenchymal transition of HCC cells

scientific article

Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide.

scientific article published on 6 March 2009

Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells.

scientific article published on May 2007

Hyperthermia enhances tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line

scientific article published on November 2003

Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells.

scientific article published on January 2004

IFN production ability and healthy ageing: mixed model analysis of a 24 year longitudinal study in Japan

scientific article published on 11 January 2013

Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry

scientific article published on 8 December 2015

Identification of dihalogenated proteins in rat intestinal mucosa injured by indomethacin.

scientific article

Identification of inflammation-related proteins in a murine colitis model by 2D fluorescence difference gel electrophoresis and mass spectrometry

scientific article

Idiopathic sudden hearing loss in patients with type 2 diabetes

scientific article published in March 2004

Impact of amino acid substitutions in hepatitis C virus genotype 1b core region on liver steatosis and glucose tolerance in non-cirrhotic patients without overt diabetes

scientific article published in May 2011

In vivo imaging of intestinal helminths by capsule endoscopy.

scientific article

Increased concentration of pentosidine, an advanced glycation end product, and interleukin-6 in the vitreous of patients with proliferative diabetic retinopathy

scientific article published in August 2003

Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis

scientific article

Increased intestinal expression of heme oxygenase-1 and its localization in patients with ulcerative colitis.

scientific article

Inflammatory response of esophageal epithelium in combined-type esophagitis in rats: a transcriptome analysis.

scientific article

Influence of vitamin E on gastric mucosal injury induced by Helicobacter pylori infection

scientific article published on 01 January 2006

Infrequent amplification of JUN in hepatocellular carcinoma.

scientific article

Ingestion of low dose pyroglutamyl leucine improves dextran sulfate sodium-induced colitis and intestinal microbiota in mice

scientific article

Inhalation of carbon monoxide ameliorates TNBS-induced colitis in mice through the inhibition of TNF-α expression

scientific article published on 22 January 2010

Inhalation of carbon monoxide ameliorates collagen-induced arthritis in mice and regulates the articular expression of IL-1beta and MCP-1.

scientific article published in April 2009

Inhibition of plasma lipid oxidation induced by peroxyl radicals, peroxynitrite, hypochlorite, 15-lipoxygenase, and singlet oxygen by clinical drugs

scientific article published on 13 October 2016

Inhibitory effect of a novel water-soluble vitamin E derivative on atherosclerosis in rabbits

scientific article

Inhibitory effect of fermented milk on delayed-onset muscle damage after exercise.

scientific article

Inhibitory effect of pioglitazone on expression of adhesion molecules on neutrophils and endothelial cells

scientific article

Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori

scientific article published on November 2002

Inhibitory effect of serotonin derivatives on high glucose-induced adhesion and migration of monocytes on human aortic endothelial cells

scientific article published on 18 February 2009

Inhibitory effects of catechins on neutrophil-dependent gastric inflammation

scientific article published on January 2002

Inhibitory effects of red wine extracts on endothelial-dependent adhesive interactions with monocytes induced by oxysterols.

scientific article published in January 2004

Integrin-linked kinase acts as a pro-survival factor against high glucose-associated osmotic stress in human mesangial cells.

scientific article published on 12 April 2006

Interferon and nucleoside analog combination therapy for hepatitis B.

scientific article published on 23 February 2010

Interferon-gamma gene dinucleotide (CA) repeat and interleukin-4 promoter region (-590C/T) polymorphisms in Japanese patients with endometriosis

scientific article published on 27 May 2004

Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon 26 adenocarcinoma in mice

scientific article published on 01 February 2005

Interleukin-6, obstructive sleep apnea, and obesity

scientific article published in October 2003

Interleukin-8 neutralization for COPD.

scientific article

Intervention with delivery of diabetic meals improves glycemic control in patients with type 2 diabetes mellitus

scientific article published on January 2008

Inverse association between Helicobacter pylori infection and allergic rhinitis in young Japanese.

scientific article published on July 2010

Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice

scientific article published on 15 September 2008

Involvement of Kupffer cells in the interaction between neutrophils and sinusoidal endothelial cells in rats

scientific article published on 01 August 2002

Involvement of reactive oxygen species in indomethacin-induced apoptosis of small intestinal epithelial cells

scientific article

Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats

scientific article published on 9 March 2010

Joint effect of alcohol and usual sleep duration on the risk of dysglycemia

scientific article

Lansoprazole ameliorates intestinal mucosal damage induced by ischemia-reperfusion in rats

scientific article published on October 2004

Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.

scientific article

Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis

scientific article published in January 2006

Laser capture microdissection/GeneChip analysis of gene expression in glomerular cells in diabetic db/db mice.

scientific article

Late preconditioning by ethanol is initiated via an oxidant-dependent signaling pathway

scientific article published in February 2003

Leukocyte-endothelial cell adhesion molecule 1 (LECAM-1) polymorphism is associated with diabetic nephropathy in type 2 diabetes mellitus

scientific article published on 01 September 2002

Lipid hydroperoxide-derived modification of proteins in gastrointestinal tract.

scientific article published on January 2014

Long fish tapeworm in the intestine: an in situ observation by capsule endoscopy

scientific article published on 15 February 2011

Long-term (>=2 yr) efficacy of vitamin E for non-alcoholic steatohepatitis

scientific article published in September 2013

Low serum dehydroepiandrosterone sulfate concentration is a predictor for deterioration of urinary albumin excretion in male patients with type 2 diabetes.

scientific article published on 4 January 2006

Low serum testosterone concentration in middle-aged men with type 2 diabetes

scientific article published on 12 November 2007

Lower circulating levels of dehydroepiandrosterone, independent of insulin resistance, is an important determinant of severity of non‐alcoholic steatohepatitis in Japanese patients

scientific article published on September 1, 2010

Lung expression of cytochrome P450 1A1 as a possible biomarker of exposure to diesel exhaust particles.

scientific article published on 20 February 2002

Malnutrition and disease progression in patients with rheumatoid arthritis

scientific article published in January 2005

Management of recurrence of symptoms of gastroesophageal reflux disease: synergistic effect of rebamipide with 15 mg lansoprazole

scientific article published on 3 March 2010

Mast cells are involved in the pathogenesis of indomethacin-induced rat enteritis

scientific article published on 16 January 2009

Methylparaben potentiates UV-induced damage of skin keratinocytes

scientific article

Microarray profiling of gene expression in human adipocytes in response to anthocyanins

scientific article published on 17 February 2006

Microarray profiling of gene expression patterns in glomerular cells of astaxanthin-treated diabetic mice: a nutrigenomic approach

scientific article published on 01 October 2006

Milk-derived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein e-deficient mice: a preliminary study

scientific article published on 30 April 2013

Molecular and cellular mechanisms involved in Helicobacter pylori-induced inflammation and oxidative stress

scientific article

Molecular characterization of a variant virus that caused de novo hepatitis B without elevation of hepatitis B surface antigen after chemotherapy with rituximab

scientific article

Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease

scientific article published on 15 October 2007

Mouse strain differences in eosinophilic airway inflammation caused by intratracheal instillation of mite allergen and diesel exhaust particles

scientific article published on 01 January 2004

Mucin-Related Molecular Responses of Bronchial Epithelial Cells in Rats Infected with the Nematode Nippostrongylus brasiliensis

scientific article published on 16 March 2013

Mucosal IgA deposition [correction of depositon] in Henoch-Schönlein purpura with duodenal ulcer

scientific article published on 01 June 2002

Multicenter study of endoscopic mucosal resection using 0.13% hyaluronic acid solution of colorectal polyps less than 20 mm in size

scientific article published on 28 December 2012

Multifaceted Assessment of Chronic Gastritis: A Study of Correlations between Serological, Endoscopic, and Histological Diagnostics

scientific article published on 10 July 2011

Multifocal Fibrosclerosis: Retroperitoneal Fibrosis Associated with a Suprasellar Tumor and Pachymeningitis

scientific article published on October 1, 2003

Multiple targets of carbon monoxide gas in the intestinal inflammation

scientific article published on April 2016

Murine strain differences in airway inflammation induced by diesel exhaust particles and house dust mite allergen.

scientific article published in July 2002

Muscle-enriched microRNA miR-486 decreases in circulation in response to exercise in young men

scientific article published on 11 April 2013

Mycoplasma fermentans glycolipid-antigen as a pathogen of rheumatoid arthritis

scientific article

Nephrotic syndrome with crescent formation and massive IgA deposition following allogeneic bone marrow transplantation for natural killer cell leukemia/lymphoma

scientific article published on 23 January 2003

Neutrophil-dependent oxidative stress in ulcerative colitis

scientific article published on July 2007

Nitrogen dioxide air pollution near ambient levels is an atherogenic risk primarily in obese subjects: a brief communication

scientific article published in April 2004

No association between the MTHFR gene polymorphism and diabetic retinopathy in type 2 diabetic patients without overt nephropathy

scientific article published in June 2003

Nonalcoholic steatohepatitis and increased risk of chronic kidney disease

scientific article published on September 3, 2010

Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels.

scientific article published on 27 November 2012

Nuclear size measurement is a simple method for the assessment of hepatocellular aging in non-alcoholic fatty liver disease: Comparison with telomere-specific quantitative FISH and p21 immunohistochemistry

scientific article published in March 2010

Oligosaccharides from agar inhibit murine intestinal inflammation through the induction of heme oxygenase-1 expression.

scientific article published on 28 November 2012

Outcome of endoscopic submucosal dissection for colorectal tumors in elderly people

scientific article published in April 2010

Oxidative stress involvement and gene expression in indomethacin-induced gastropathy

scientific article published on January 2006

Oxidative stress is closely associated with tumor angiogenesis of hepatocellular carcinoma.

scientific article

Oxidative stress may enhance the malignant potential of human hepatocellular carcinoma by telomerase activation

scientific article published on 24 December 2008

Oxidative stress-induced posttranslational modification of TRPV1 expressed in esophageal epithelial cells

scientific article published on 2 June 2011

Oxidative stress-induced posttranslational modification of proteins as a target of functional food

scientific article published on 07 April 2009

PEG10 is a probable target for the amplification at 7q21 detected in hepatocellular carcinoma

scientific article published on April 2010

Partially hydrolysed guar gum ameliorates murine intestinal inflammation in association with modulating luminal microbiota and SCFA.

scientific article

Partially hydrolyzed guar gum affects the expression of genes involved in host defense functions and cholesterol absorption in colonic mucosa of db/db male mice

scientific article

Partially hydrolyzed guar gum down-regulates colonic inflammatory response in dextran sulfate sodium-induced colitis in mice

scientific article

Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer

scientific article

Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer.

scientific article

Pioglitazone, a PPAR-gamma ligand, provides protection from dextran sulfate sodium-induced colitis in mice in association with inhibition of the NF-kappaB-cytokine cascade

scientific article published in January 2002

Plasma lipid oxidation induced by peroxynitrite, hypochlorite, lipoxygenase and peroxyl radicals and its inhibition by antioxidants as assessed by diphenyl-1-pyrenylphosphine

scientific article published on 11 January 2016

Points of control exerted along the macrophage-endothelial cell-polymorphonuclear neutrophil axis by PECAM-1 in the innate immune response of acute colonic inflammation

scientific article published in August 2008

Polymorphisms of interferon-gamma gene CA-repeat and interleukin-10 promoter region (-592A/C) in Japanese type I diabetes

scientific article published on 01 February 2002

Possible involvement of TNF-alpha in left ventricular remodeling in hemodialysis patients.

scientific article published in September 2003

Potential role of oxidative protein modification in energy metabolism in exercise

scientific article published on January 2014

Preconditioning with ethanol prevents postischemic leukocyte-endothelial cell adhesive interactions

scientific article published in September 2002

Prediction of Large Esophageal Variceal Bleeding and Subsequent Mortality

scientific article published on May 2014

Prevention by rebamipide of acute reflux esophagitis in rats

scientific article published in October 2005

Prevention of Indomethacin-Induced Gastric Mucosal Injury in Helicobacter pylori-Negative Healthy Volunteers: A Comparison Study Rebamipide vs Famotidine

scientific article published on July 2008

Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice

scientific article published in January 2004

Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice.

scientific article published in February 2014

Pro-oxidant action of pyrroloquinoline quinone: characterization of protein oxidative modifications

scientific article published on 7 March 2010

Proinflammatory role of protease-activated receptor-2 in intestinal ischemia/reperfusion injury in rats.

scientific article published on 21 October 2010

Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution

scientific journal article

Propionate Promotes Fatty Acid Oxidation through the Up-Regulation of Peroxisome Proliferator-Activated Receptor α in Intestinal Epithelial Cells

scientific article published on January 2015

Protease-antiprotease imbalance in inflammatory diseases in the lung

scientific article published on 01 August 2005

Protective effect of agaro-oligosaccharides on gut dysbiosis and colon tumorigenesis in high-fat diet-fed mice

scientific article published on 14 January 2016

Protective effect of serotonin derivatives on glucose-induced damage in PC12 rat pheochromocytoma cells

scientific article published on 14 September 2009

Protective effect of the Japanese traditional medicine juzentaihoto on myelosuppression induced by the anticancer drug TS-1 and identification of a potential biomarker of this effect

scientific article

Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats

scientific article published in April 2004

Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide

scientific article published on 31 October 2008

Protective role of interleukin-6 in coagulatory and hemostatic disturbance induced by lipopolysaccharide in mice

scientific article published on 01 June 2004

Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide

scientific article published in April 2005

Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice

scientific article published in January 2009

Pulmonary exposure to diesel exhaust particles enhances coagulatory disturbance with endothelial damage and systemic inflammation related to lung inflammation

scientific article published in November 2006

Pulmonary exposure to diesel exhaust particles induces airway inflammation and cytokine expression in NC/Nga mice

scientific article

Randomized controlled trial of two forms of self-management group education in Japanese people with impaired glucose tolerance

scientific article published on September 2008

Rapid assessment of singlet oxygen-induced plasma lipid oxidation and its inhibition by antioxidants with diphenyl-1-pyrenylphosphine (DPPP).

scientific article published on 14 October 2015

Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury

scientific article

Rebamipide ameliorates indomethacin-induced small intestinal injury in rats via the inhibition of matrix metalloproteinases activity

scientific article

Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution.

scientific article

Rebamipide, a gastro-protective and anti-inflammatory drug, promotes gastric ulcer healing following eradication therapy for Helicobacter pylori in a Japanese population: a randomized, double-blind, placebo-controlled trial

scientific article published on 24 August 2007

Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression

scientific article published in October 2005

Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice

scientific article published on 01 August 2004

Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice

scientific article published on 01 February 2011

Reduction of diabetes-induced renal oxidative stress by a cantaloupe melon extract/gliadin biopolymers, oxykine, in mice

scientific article published in January 2005

Regular exercise reduces colon tumorigenesis associated with suppression of iNOS.

scientific article published on 13 July 2010

Relapse of hepatitis C in a pegylated-interferon-alpha-2b plus ribavirin-treated sustained virological responder

scientific article published on June 2010

Relationship between insulin resistance and inflammatory markers and anti-inflammatory effect of losartan in patients with type 2 diabetes and hypertension.

scientific article published on 12 June 2006

Relationship between low serum endogenous androgen concentrations and arterial stiffness in men with type 2 diabetes mellitus

scientific article published on 01 September 2007

Relationship between polymorphisms 804C/A and 252A/G of lymphotoxin-alpha gene and -308G/A of tumor necrosis factor alpha gene and diabetic retinopathy in Japanese patients with type 2 diabetes mellitus.

scientific article

Relationship of serum brain-derived neurotrophic factor level with other markers of disease severity in patients with atopic dermatitis.

scientific article published on 11 December 2006

Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study

scientific article published on 19 May 2015

Relaxant effect of microtitan via regulation of autonomic nerve activity in mice.

scientific article published on 24 July 2009

Reply to the letter from Dr. Miao et al

scientific article published on September 2016

Response to Oncül: insulin sensitivity in patients with chronic hepatitis C virus infection

scientific article published in October 2002

Rituximab is effective for human herpesvirus-8-negative primary effusion lymphoma with CD20 phenotype associated hepatitis C virus-related liver cirrhosis

scientific article published in December 2004

Role of calcitonin gene-related peptide in the postischemic anti-inflammatory effects of antecedent ethanol ingestion

scientific article

Role of eNOS-derived NO in the postischemic anti-inflammatory effects of antecedent ethanol ingestion in murine small intestine

scientific article published on 10 November 2006

Role of endogenous androgen against insulin resistance and athero- sclerosis in men with type 2 diabetes

scientific article published on February 2007

Role of interleukin-6 in toll-like receptor 4 and 2 expressions induced by lipopolysaccharide in the lung

scientific article published on 01 January 2007

Role of matrix metalloproteinases in inflammatory bowel disease

scientific article

Role of metallothionein in antigen-related airway inflammation

scientific article published in January 2005

Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide in mice.

scientific article

Role of nociceptors/neuropeptides in the pathogenesis of visceral hypersensitivity of nonerosive reflux disease

scientific article published on 17 August 2012

Role of oxidative stress in impaired insulin signaling associated with exercise-induced muscle damage

scientific article published on 27 September 2013

Role of oxygen-derived free radicals in Helicobacter pylori water extract-induced mouse skin carcinogenesis.

scientific article published in January 2006

Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats

scientific article

Role of the thrombin/protease-activated receptor 1 pathway in intestinal ischemia-reperfusion injury in rats.

scientific article

Rosmarinic acid inhibits epidermal inflammatory responses: anticarcinogenic effect of Perilla frutescens extract in the murine two-stage skin model

scientific article

Rosmarinic acid inhibits lung injury induced by diesel exhaust particles.

scientific article published in April 2003

Rosmarinic acid, a major polyphenolic component of Perilla frutescens, reduces lipopolysaccharide (LPS)-induced liver injury in D-galactosamine (D-GalN)-sensitized mice

scientific article

Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein

scientific article

Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice.

scientific article published in June 2006

Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced intestinal mucosal damage in rats

scientific article published on January 2004

S-allyl cysteine ameliorates the quality of sperm and provides protection from age-related sperm dysfunction and oxidative stress in rats

scientific article published on 21 October 2014

SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma

scientific article published on October 15, 2010

SOX2 promotes tumor growth of esophageal squamous cell carcinoma through the AKT/mammalian target of rapamycin complex 1 signaling pathway

scientific article published on 16 April 2013

Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer

scientific article published on 22 December 2010

Serpin B1 protects colonic epithelial cell via blockage of neutrophil elastase activity and its expression is enhanced in patients with ulcerative colitis.

scientific article

Serum dehydroepiandrosterone sulfate concentration and carotid atherosclerosis in men with type 2 diabetes.

scientific article published on 25 February 2005

Serum extracellular superoxide dismutase in patients with type 2 diabetes: relationship to the development of micro- and macrovascular complications

scientific article published in April 2003

Serum prostate-specific antigen levels in men with type 2 diabetes

scientific article published on 14 February 2008

Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitus

scientific article published on 01 May 2008

Short-term exposure of high glucose concentration induces generation of reactive oxygen species in endothelial cells: implication for the oxidative stress associated with postprandial hyperglycemia

scientific article

Short-term high glucose exposure induces monocyte-endothelial cells adhesion and transmigration by increasing VCAM-1 and MCP-1 expression in human aortic endothelial cells

scientific article published on 13 November 2006

Short-term intensive insulin therapy in newly diagnosed type 2 diabetes: response to Ryan, Imes, and Wallace

scientific article published on 01 September 2004

Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats via a NO/cGMP-dependent mechanism

scientific article

Silver nanoparticles as a safe preservative for use in cosmetics

scholarly article by Satoshi Kokura et al published August 2010 in Nanomedicine: Nanotechnology, Biology and Medicine

Simple formula to predict response to peginterferon alpha2b and ribavirin combination therapy in genotype 1 chronic hepatitis C patients with high viral loads

scientific article published in February 2011

Singlet oxygen quenching activity of human serum

scientific article published on 01 January 2004

Six new chalcones from Angelica keiskei inducing adiponectin production in 3T3-L1 adipocytes

scientific article

Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart

scientific article published in October 2005

Statin, inflammation, and sepsis.

scientific article

Statistical identification of predictors for peripheral neuropathy associated with administration of bortezomib, taxanes, oxaliplatin or vincristine using ordered logistic regression analysis

scientific article published on October 2010

Steatosis and hepatic expression of genes regulating lipid metabolism in Japanese patients infected with hepatitis C virus.

scientific article

Successful endoscopic hemostasis for ruptured duodenal varices after balloon-occluded retrograde transvenous obliteration

scientific article published on October 2010

Successful endoscopic injection sclerotherapy of high-risk gastroesophageal varices in a cirrhotic patient with hemophilia A.

scientific article published on 29 April 2010

Successful treatment of non-Hodgkin's lymphoma complicated with autoimmune neutropenia

scientific article published on 01 July 2002

Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.

scientific article

Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency

Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-gamma ligand, pioglitazone, in rats

scientific article published in January 2002

Surgical stress in ARDS open-lung biopsy

scientific article published in October 2004

Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epithelium

scientific article

Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection.

scientific article

Synergistic effect of interleukin-6 promoter (IL6 -634C/G) and intercellular adhesion molecule-1 (ICAM-1 469K/E) gene polymorphisms on the risk of endometriosis in Japanese women.

scientific article

The 'donations for decreased ALT (D4D)' prosocial behavior incentive scheme for NAFLD patients

scientific article published on 6 October 2013

The alpha-glucosidase inhibitor acarbose reduces the net electronegative charge of low-density lipoprotein in patients with newly diagnosed type 2 diabetes

scientific article published on 12 January 2008

The association of insomnia with gastroesophageal reflux symptoms in biopsy-proven nonalcoholic fatty liver disease.

scientific article

The astaxanthin-induced improvement in lipid metabolism during exercise is mediated by a PGC-1α increase in skeletal muscle

scientific article published on 19 February 2014

The expression of heme oxygenase-1 induced by lansoprazole

scientific article published on 30 June 2009

The fatty acid composition of plasma cholesteryl esters and estimated desaturase activities in patients with nonalcoholic fatty liver disease and the effect of long-term ezetimibe therapy on these levels

scientific article published on 21 July 2010

The high incidence of left atrial appendage thrombosis in patients on maintenance haemodialysis

scientific article published on November 1, 2003

The impact of non-steroidal anti-inflammatory drugs on the small intestinal epithelium.

scientific article published on 18 December 2013

The inhibitory effect of alacepril, an angiotensin-converting enzyme inhibitor, on endothelial inflammatory response induced by oxysterol and TNF-alpha

scientific article

The microRNA miR-696 regulates PGC-1{alpha} in mouse skeletal muscle in response to physical activity

scientific journal article

The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kappaB.

scientific article published on 10 August 2005

The role of heme oxygenase and carbon monoxide in inflammatory bowel disease

scientific article published on January 2010

The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles.

scientific article published on 28 October 2005

Thr54 allele of the FABP2 gene affects resting metabolic rate and visceral obesity

scientific article

Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer

scientific article

Titanium-treated surroundings attenuate psychological stress associated with autonomic nerve regulation in office workers with daily emotional stress

scientific article published on 23 September 2012

Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expression of adhesion molecules

scientific article published on 12 January 2005

Transcriptome Analysis for Cytoprotective Actions of Rebamipide against Indomethacin-Induced Gastric Mucosal Injury in Rats.

scientific article

Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB.

scientific article published on 27 January 2004

Tumor suppressive effects of tocotrienol in vivo and in vitro

scientific article published on 10 August 2005

Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.

scientific article published on 27 April 2009

Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide

scientific article published on 2 December 2004

Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

scientific article

Vascular permeability in active pulmonary tuberculosis.

scientific article published in March 2005

Vitamin E as a regulator of host defense against infection

scientific article published on 01 October 2004

Whole blood interferon-γ levels predict the therapeutic effects of adoptive T-cell therapy in patients with advanced pancreatic cancer

scientific article published on 29 March 2013

Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice

scientific article published in May 2007

Zinc finger protein 28 as a novel melanoma-related molecule.

scientific article published on 28 March 2009

[A case of Castleman disease arising from lesser sac].

scientific article

[A case of Morgagni hernia prolapsed with the stomach, greater omentum and transverse colon]

scientific article published on 01 January 2002

[A case of ulcerative colitis complicated with deep venous thrombosis and pulmonary embolism]

scientific article published on 01 May 2005

[Antibodies to GM1 and GQ1b gangliosides]

scientific article published on 01 July 2005

[Autoantibodies to ganglioside and sulphatide in diabetes mellitus]

scientific article published on 01 August 2002

[Autoimmune disease]

scientific article published on 01 April 2005

[Oxidative stress evaluated by oxidative stress profile (OSP)]

scientific article published on 01 November 2004

[Pro-inflammatory chemokine IL-8 in gastroesophageal reflux disease]

scientific article published on 01 August 2004

[Reactive oxygen species and free radicals are involved in pathophysiology of brain ischemia]

scientific article published on 01 October 2006

alpha-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice

scientific article published in February 2002