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List of works by Paola Zigrino

A Disintegrin and Metalloprotease (ADAM): Historical Overview of Their Functions

scientific article

A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses

scientific article

ADAM-9 functions as cell???cell receptor between melanoma cells and fibroblasts

ADAM9

Accelerated Wound Repair in ADAM-9 Knockout Animals

scientific article published on 08 April 2010

Adam-9 expression and regulation in human skin melanoma and melanoma cell lines

scientific article

CD30 on extracellular vesicles from malignant Hodgkin cells supports damaging of CD30 ligand-expressing bystander cells with Brentuximab-Vedotin, in vitro

scientific article published on 20 April 2016

Cell-Populated Collagen Lattice Models

scientific article published in January 2017

Collagen-induced proMMP-2 activation by MT1-MMP in human dermal fibroblasts and the possible role of ?2?1 integrins

scientific article published on 01 January 2001

Contact of high-invasive, but not low-invasive, melanoma cells to native collagen I induces the release of mature cathepsin B.

scientific article published in June 2006

Delayed wound healing and epidermal hyperproliferation in mice lacking JunB in the skin

scientific article published in April 2006

Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis

scientific article published on 29 May 2017

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

scientific article

Dual role of laminin‑511 in regulating melanocyte migration and differentiation

scientific article published on 29 September 2018

Epidermal NLRP10 contributes to contact hypersensitivity responses in mice

scientific article published on 25 May 2016

Eradication of melanomas by targeted elimination of a minor subset of tumor cells

scientific article

Evidence for a K+ channel requirement in spreading of rat basophilic leukemia cells on fibronectin-coated surfaces

scientific article published on April 1996

Expression of matrix metalloproteinase (MMP)-2, MMP-9, MMP-13, and MT1-MMP in skin tumors of human papillomavirus type 8 transgenic mice

scientific article published on 01 January 2006

Fibrillin microfibrils and proteases, key integrators of fibrotic pathways

scientific article published on 27 April 2018

Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin

scientific article published on 8 April 2016

Fibroblast-matrix interactions in wound healing and fibrosis.

scientific article

Gene expression profiling reveals cross-talk between melanoma and fibroblasts: implications for host-tumor interactions in metastasis

scientific article

High Invasive Melanoma Cells Induce Matrix Metalloproteinase-1 Synthesis in Fibroblasts by Interleukin-1α and Basic Fibroblast Growth Factor-Mediated Mechanisms

scientific article published on 01 March 2005

Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype.

scientific article

Host response to human breast Invasive Ductal Carcinoma (IDC) as observed by changes in the stromal proteome

scientific article

Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts

scientific article published on 05 August 2005

Human papillomavirus type 197 is not associated with skin tumors

scientific article published on 10 September 2019

Human papillomavirus type 8 E6 oncoprotein inhibits transcription of the PDZ protein syntenin-2.

scientific article

IAP antagonization promotes inflammatory destruction of vascular endothelium

scientific article published on 30 March 2015

Identification and discrimination of extracellularly active cathepsins B and L in high-invasive melanoma cells

scientific article published on 9 February 2006

Induction of Inflammatory Cytokines by a Keratin Mutation and their Repression by a Small Molecule in a Mouse Model for EBS

scientific article published on 21 June 2007

Integrin expression and adhesion property of osteoclast-like cells from giant cell tumours of bone

scientific article published on 01 April 1992

Invasion of melanoma cells into dermal connective tissue in vitro: evidence for an important role of cysteine proteases

scientific article published in September 2003

Lack of integrin β5 in Merkel cell carcinomas and derived cell lines is frequently associated with Merkel cell polyomavirus positivity

scientific article published on 30 March 2012

Leucurogin and melanoma therapy

scientific article published on 03 January 2019

Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth

scientific article published on 07 September 2020

Loss of epidermal MMP-14 expression interferes with angiogenesis but not with re-epithelialization.

scientific article published on 18 June 2012

Matrix metalloproteinase 14 is required for fibrous tissue expansion

scientific article published on 21 September 2015

Melanoma cell-derived vascular endothelial growth factor induces endothelial tubulogenesis within fibrin gels by a metalloproteinase-mediated mechanism

scientific article published on 01 September 2006

Metalloproteinases in melanoma

scientific article published on 27 January 2014

Monocyte/Macrophage MMP-14 Modulates Cell Infiltration and T-Cell Attraction in Contact Dermatitis But Not in Murine Wound Healing

scientific article published on 01 March 2013

NLRP10 enhances Shigella-induced pro-inflammatory responses

scientific article

New model for bone resorption study in vitro: human osteoclast-like cells from giant cell tumors of bone.

scientific article

No Evidence for Role of Cutavirus in Malignant Melanoma

scientific article published on 01 August 2019

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis

scientific article published on 25 September 2018

Platelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9.

scientific article

Primary tumor versus metastasis: new experimental models for studies on cancer cell homing and metastasis in melanoma

scientific article published on 6 January 2014

Proteases in Melanoma

Proteases in Melanoma

Proteomic analysis reveals the actin cytoskeleton as cellular target for the human papillomavirus type 8

scientific article published on 24 February 2009

Proteomic anatomy of human skin

scientific article

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas

scientific article published on 11 July 2018

Regulation of MMP expression by 3-dimensional fibrin and collagen matrices

scholarly article by K. Breitkopf published in March 1998

Role of ADAM-15 in wound healing and melanoma development

scientific article published on June 2012

Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration

scientific article

Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice

scientific article published on 14 September 2016

Role of aPKC Isoforms and Their Binding Partners Par3 and Par6 in Epidermal Barrier Formation

scientific article published on 16 November 2006

Role of the snake venom toxin jararhagin in proinflammatory pathogenesis: in vitro and in vivo gene expression analysis of the effects of the toxin

scientific article

Stromal Expression of MMP-13 Is Required for Melanoma Invasion and Metastasis

scientific article published on 11 June 2009

Stromal fibroblast-specific expression of ADAM-9 modulates proliferation and apoptosis in melanoma cells in vitro and in vivo

scientific article published on 24 May 2012

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes

scientific article

The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival

scientific article published on 18 February 2019

The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts

scientific article published on 6 December 2010

The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo

scientific article

The proteasome inhibitor bortezomib sensitizes melanoma cells toward adoptive CTL attack

scientific article

The reprolysin jararhagin, a snake venom metalloproteinase, functions as a fibrillar collagen agonist involved in fibroblast cell adhesion and signaling

scientific article published on 16 August 2002

Tissue Inhibitor of Matrix Metalloproteinase-2 Regulates Matrix Metalloproteinase-2 Activation by Modulation of Membrane-type 1 Matrix Metalloproteinase Activity in High and Low Invasive Melanoma Cell Lines

scientific article published in Journal of Biological Chemistry

Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs

scientific article published on October 2002

Tumor-stroma interactions: their role in the control of tumor cell invasion.

scientific article

Tumorstroma interactions: their role in the control of tumor cell invasion and metastasis

scientific article published on 01 June 2006

Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA.

scientific article published on 14 March 2013

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