List of works - Elisabeth Kremmer

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

scientific article

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

scientific article

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein

scientific article

A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses

scientific article

Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates

scientific article

Atad3 Function Is Essential for Early Post-Implantation Development in the Mouse ⬇️

scientific article published on January 25, 2013

DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex

scientific journal article

Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs

scientific article (publication date: 15 May 2004)

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex

scientific article

Granulin knock out zebrafish lack frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis pathology

scientific article

Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases

scientific article

HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals

scientific journal article

HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases

scientific article

Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis

scientific article

Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs

scientific article

Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells

scientific article

Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit

scientific article

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

scientific article

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

scientific article

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing

scientific journal article

NLRP10 enhances Shigella-induced pro-inflammatory responses

scientific article

NSP4, an elastase-related protease in human neutrophils with arginine specificity ⬇️

scientific article published on April 2, 2012

Nodular inflammatory foci are sites of T cell priming and control of murine cytomegalovirus infection in the neonatal lung

scientific article

Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway

scientific article

O-fucosylation of DLL3 is required for its function during somitogenesis

scientific article

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

scientific article

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation

scientific article

Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus

scientific article (publication date: July 2002)

Protein arginine methylation during lytic adenovirus infection

scientific article

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

scientific article

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

scientific article

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b

scientific article

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

scientific article

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression

scientific journal article

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation

scientific journal article

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin

scientific article

SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation

scientific article

Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation

scientific article

Subunit stoichiometry of the CNG channel of rod photoreceptors

scientific journal article

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

scientific article

The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens

scientific article (publication date: August 2007)

The human trithorax protein hASH2 functions as an oncoprotein

scientific article

The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein

scientific article

The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13

scientific article (publication date: June 2003)

The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance

scientific article

Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex

scientific article

List of works by Elisabeth Kremmer

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein

A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses

Aldo-keto Reductase 1B15 (AKR1B15): a mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates

Atad3 Function Is Essential for Early Post-Implantation Development in the Mouse ⬇️

DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex

Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs

Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex

Granulin knock out zebrafish lack frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis pathology

Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases

HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals

HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases

Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis

Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs

Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells

Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing

NLRP10 enhances Shigella-induced pro-inflammatory responses

NSP4, an elastase-related protease in human neutrophils with arginine specificity ⬇️

Nodular inflammatory foci are sites of T cell priming and control of murine cytomegalovirus infection in the neonatal lung

Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway

O-fucosylation of DLL3 is required for its function during somitogenesis

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation

Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus

Protein arginine methylation during lytic adenovirus infection

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin

SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation

Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation

Subunit stoichiometry of the CNG channel of rod photoreceptors

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens

The human trithorax protein hASH2 functions as an oncoprotein

The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein

The sphingosine 1-phosphate receptor S1P4 regulates cell shape and motility via coupling to Gi and G12/13

The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance

Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex