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List of works by Pekka Kohonen

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

scientific article

A data fusion pipeline for generating and enriching Adverse Outcome Pathway descriptions

scientific article published on 15 November 2017

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

scientific article from 2017

Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions

scientific article

Androgen regulation of micro-RNAs in prostate cancer

scientific article published on 13 October 2010

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

scientific article

Avian Helios and evolution of the Ikaros family

scientific article published in July 2004

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

scientific article published on March 2014

Can an InChI for Nano Address the Need for a Simplified Representation of Complex Nanomaterials across Experimental and Nanoinformatics Studies?

scientific article published on 11 December 2020

Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

scientific article (publication date: 23 May 2014)

Chapter 11. Computational Modelling of Biological Responses to Engineered Nanomaterials

Chicken B-cell-activating factor: regulator of B-cell survival in the bursa of fabricius

scientific article published on May 2004

Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP.

scientific article published on September 2010

Development of early PCLP1-expressing haematopoietic cells within the avian dorsal aorta

scientific article published in September 2005

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scientific article published on 30 March 2010

Enriching Nanomaterials Omics Data: An Integration Technique to Generate Biological Descriptors

scientific article published on 12 October 2017

ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.

scientific article

Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scholarly article published in Breast Cancer Research and Treatment

Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

scientific article

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets

scientific article

Genotoxic and epigenetic effects of silver nanoparticles

scholarly article by Hanna L. Karlsson et al published June 2012 in Toxicology Letters

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation

scientific article

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer

scientific article published on March 2016

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

scientific article

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

scientific article

Identification of a novel cytokine-like transcript differentially expressed in avian gammadelta T cells

scientific article published on 4 February 2004

Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact

scientific article

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

scientific article

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

scientific article published on 9 September 2013

Insight into lymphoid development by gene expression profiling of avian B cells.

scientific article

Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models

scholarly article by Noffisat O. Oki et al published February 2019 in Toxicology in Vitro

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer

scientific article published on 14 September 2011

Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

scientific article

Loss of Pax5 promotes plasma cell differentiation

scientific article published on March 2006

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

scientific article published on 26 September 2011

Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors

journal article published in 2018

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

scientific article

Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases

scientific article published on 26 October 2012

P26. MicroRNA expression profiling and functional screening in bone metastatic breast cancer cells

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

scientific article

Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

scientific article

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages

scientific article published on 07 October 2015

RDFIO: extending Semantic MediaWiki for interoperable biomedical data management

scientific article

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue

scientific article published on 19 October 2015

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

scientific article

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

scientific article published on 28 November 2011

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

scientific article (publication date: 2013)

The eNanoMapper database for nanomaterial safety information

scientific article

The eNanoMapper database for nanomaterial safety information

The first eNanoMapper prototype: A substance database to support safe-by-design ⬇️

scientific article (publication date: November 2014)

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

scientific article published on 08 January 2020

Towards FAIR nanosafety data

Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome.

scientific article published in April 2018

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

scientific article published on 15 April 2020

Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data

scientific article published on 08 May 2020

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

scientific article published on 08 April 2020

miR-183 in prostate cancer cells positively regulates synthesis and serum levels of prostate-specific antigen

scientific article

toxFlow: a Web-Based Application for Read-Across Toxicity Prediction using Omics and Physicochemical Data.

scientific article published on 27 December 2017

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