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List of works by François Lanza

A 13 base pair deletion in the GPIbbeta gene in a second unrelated Bernard-Soulier family due to slipped mispairing between direct repeats

scientific article published on 01 September 2004

A PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1

scientific article (publication date: 8 May 2003)

A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbalpha N-terminal extracellular domain.

scientific article published on 10 May 2010

A general approach to the generation of monoclonal antibodies against members of the tetraspanin superfamily using recombinant GST fusion proteins

scientific article published on 01 October 1999

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

scientific article

A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation ⬇️

scientific article published on June 1, 1992

A novel monoclonal antibody against the extracellular domain of GPIbbeta modulates vWF mediated platelet adhesion.

scientific article published in November 2001

A novel platelet-type von Willebrand disease mutation (GP1BA p.Met255Ile) associated with type 2B "Malmö/New York" von Willebrand disease.

scientific article published on 29 September 2016

A second report of platelet-type von Willebrand disease with a Gly233Ser mutation in the GPIBA gene

scientific article published on 01 February 2007

A study of platelet activation in atrial fibrillation and the effects of antithrombotic therapy

scientific article (publication date: November 2002)

A three-base deletion removing a leucine residue in a leucine-rich repeat of platelet glycoprotein Ib alpha associated with a variant of Bernard-Soulier syndrome (Nancy I)

scientific article published on 01 February 1995

A unique microenvironment in the developing liver supports the expansion of megakaryocyte progenitors

scientific article published on 26 September 2017

Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation.

scientific article

Activation of the fibrinogen binding site on platelets isolated from a patient with the Strasbourg I variant of Glanzmann's thrombasthenia

scientific article published on 01 August 1994

An essential role for α4A-tubulin in platelet biogenesis

scientific article published on 13 February 2019

Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization

scientific article published on 24 October 2009

Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets

scientific article published on 10 March 2016

Bernard-Soulier syndrome (hemorrhagiparous thrombocytic dystrophy)

scientific article

Biochemical and molecular basis of Bernard-Soulier syndrome: a review

scientific article published on 01 January 1995

Biogenesis of the demarcation membrane system (DMS) in megakaryocytes

scientific article

Biosynthesis and intracellular post-translational processing of normal and mutant platelet glycoprotein GPIb-IX

scientific article

Biosynthesis of platelet glycoprotein V expressed as a single subunit or in association with GPIb-IX.

scientific article published in September 2004

Blocking platelet aggregation inhibits thromboxane A2 formation by low dose agonists but does not inhibit phosphorylation and activation of cytosolic phospholipase A2

scientific article published on 01 October 1997

Blood platelet formation at a glance

scientific article published on 30 October 2020

Broader expression of the mouse platelet factor 4-cre transgene beyond the megakaryocyte lineage.

scientific article published on 17 December 2014

CD9 negatively regulates integrin alphaIIbbeta3 activation and could thus prevent excessive platelet recruitment at sites of vascular injury.

scientific article published on 18 February 2009

CD9 participates in endothelial cell migration during in vitro wound repair

scientific article published on 01 February 2000

CD9, a tetraspan transmembrane protein, renders cells susceptible to canine distemper virus.

scientific article published in January 1997

Characterization of megakaryocyte development in the native bone marrow environment

scientific article published on 01 January 2012

Circulating procoagulant microparticles and soluble GPV in myocardial infarction treated by primary percutaneous transluminal coronary angioplasty. A possible role for GPIIb-IIIa antagonists

scientific article (publication date: July 2004)

Co-localization of CD9 and GPIIb-IIIa (alpha IIb beta 3 integrin) on activated platelet pseudopods and alpha-granule membranes

scientific article published on 01 February 1997

Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis

scientific article published on 01 August 2019

Cyclic nucleotide phosphodiesterase inhibitors prevent aggregation of human platelets by raising cyclic AMP and reducing cytoplasmic free calcium mobilization

scientific article published on 01 March 1987

Detection by PCR and HphI restriction analysis of a splice site mutation at the 5' end of intron 15 of the platelet GPIIb (alpha IIb integrin) gene responsible for Glanzmann's thrombasthenia type I in Gypsies originating from the Strasbourg area

scientific article published on 01 September 1995

Differential effects of extra- and intracellular calcium chelation on human platelet function and glycoprotein IIb-IIIa complex stability

scientific article published on 01 January 1992

Dual role of IL-21 in megakaryopoiesis and platelet homeostasis

scientific article published on 5 January 2017

Epinephrine potentiates human platelet activation but is not an aggregating agent

scientific article published on 01 December 1988

Evaluation of soluble glycoprotein V as a marker of venous thromboembolism.

scientific article published on 24 November 2011

Expression of platelet glycoprotein (GP) V in heterologous cells and evidence for its association with GP Ib alpha in forming a GP Ib-IX-V complex on the cell surface.

scientific article

FAK-mediated inhibition of vascular smooth muscle cell migration by the tetraspanin CD9.

scientific article published in June 2002

Fibrillar cellular fibronectin supports efficient platelet aggregation and procoagulant activity.

scientific article published on 6 August 2015

Functional characterization of the human platelet glycoprotein V gene promoter: A specific marker of late megakaryocytic differentiation

scientific article published on 01 November 1999

Further evidence that fibrillar collagen is unable to promote platelet shape change and aggregation in the absence of secondary agonists

scientific article published on 01 September 2005

Further evidence that fibrillar collagen is unable to promote platelet shape change and aggregation in the absence of secondary agonists. Reply to a rebuttal.

scientific article published in January 2006

GPV is a marker of in vivo platelet activation--study in a rat thrombosis model

scientific article published on 01 February 2000

Gene cloning of rat and mouse platelet glycoprotein V: identification of megakaryocyte-specific promoters and demonstration of functional thrombin cleavage

scientific article (publication date: May 1997)

Glycoprotein (GP) Ib-IX-transfected cells roll on a von Willebrand factor matrix under flow. Importance of the GPib/actin-binding protein (ABP-280) interaction in maintaining adhesion under high shear

scientific article published on 01 March 1999

Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype

scientific article published on 01 December 1999

Haemorrhagic and thrombotic diatheses in mouse models with thrombocytosis

scientific article published on 09 October 2014

Hemostasis imbalance in experimental hypertension.

scientific article

Hirudin and heparin enable efficient megakaryocyte differentiation of mouse bone marrow progenitors

scientific article published on 08 October 2011

Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments

scientific article published on 01 December 2003

Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets.

scientific article published on 24 June 2009

Identification of thrombin receptors in rat brain capillary endothelial cells.

scientific article published in January 2000

Imaging thrombosis with 99mTc-labeled RAM.1-antibody in vivo

scientific article published on 17 March 2018

Immature myeloid dendritic cells capture and remove activated platelets from preformed aggregates

scientific article published on 01 October 2010

Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation.

scientific article published on 8 August 2016

Increased aggregation and secretion responses of human platelets when loaded with the calcium fluorescent probes quin2 and fura-2

scientific article published on 01 August 1987

Increased plasma levels of soluble platelet glycoprotein V in patients with acute myocardial infarction

scientific article published on 01 August 2003

Increased platelet glycoprotein V levels in patients with coronary and peripheral atherosclerosis--the influence of aspirin and cigarette smoking

scientific article (publication date: September 2001)

Inhibition of adhesive and signaling functions of the platelet GPIb-V-IX complex by a cell penetrating GPIbalpha peptide.

scientific article published in December 2006

Inhibition of platelet aggregation by abciximab but not by aspirin can be detected by a new point-of-care test, the hemostatus

scientific article published on 01 July 1999

Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL

scientific article

Interaction between Platelet Glycoprotein Ibα and Filamin-1 Is Essential for Glycoprotein Ib/IX Receptor Anchorage at High Shear ⬇️

scientific article published on November 7, 2001

Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome.

scientific article

Lentiviral gene rescue of a Bernard-Soulier mouse model to study platelet glycoprotein Ibβ function.

scientific article

Maternal-fetal chikungunya infection associated with Bernard-Soulier syndrome ⬇️

scientific article published on January 26, 2011

Measurement of GPV released by activated platelets using a sensitive immunocapture ELISA--its use to follow platelet storage in transfusion

scientific article published on 01 January 1999

Mechanisms underlying FeCl3-induced arterial thrombosis

scientific article published on 01 April 2011

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

scientific article

Microtubule plus-end tracking Adenopolyposis Coli negatively regulates proplatelet formation

scientific article published in Scientific Reports

Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets.

scientific article

Murine models of platelet diseases

scientific article

Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets.

scientific article

Normal ADP-induced aggregation and absence of dissociation of the membrane GP IIb-IIIa complex of intact rat platelets pretreated with EDTA

scientific article published on 01 August 1991

Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists.

scientific article published in October 2009

Novel Function of Tenascin-C, a Matrix Protein Relevant to Atherosclerosis, in Platelet Recruitment and Activation Under Flow

scientific article published on 22 July 2010

On the Way to Platelet Production

article

On the way to in vitro platelet production

article

Overexpression of tetraspanin CO-029 in hepatocellular carcinoma ⬇️

scientific article published on November 1, 2001

PF4 inhibits thrombin-stimulated MMP-1 and MMP-3 metalloproteinase expression in human vascular endothelial cells

scientific article published on 01 November 1997

Plasma glycoprotein V levels in the general population: normal distribution, associated parameters and implications for clinical studies.

scientific article published in October 2006

Plasma levels of soluble platelet glycoprotein V are linked to fasting blood glucose in patients with type 2 diabetes.

scientific article published in October 2008

Platelet activation revealed by reduced serotonin content in various left ventricular hypertrophic states

scientific article published on 01 January 1992

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor

scientific article published on 27 September 2016

Platelet functions, alpha 2-adrenergic receptors and cytoplasmic free calcium are normal in the myotonic dystrophy of Steinert.

scientific article

Platelets and arterial thrombosis

scientific article (publication date: 2003)

Platelets in cancer. From basic research to therapeutic implications.

scientific article published on 20 August 2015

Potentiation by adrenaline of human platelet activation and the inhibition by the alpha-adrenergic antagonist nicergoline of platelet adhesion, secretion and aggregation.

scientific article

Profiling of the Tetraspanin Web of Human Colon Cancer Cells

scientific article published on 07 February 2006

Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice.

scientific article

Proteolysis of the exodomain of recombinant protease-activated receptors: prediction of receptor activation or inactivation by MALDI mass spectrometry.

scientific article

Reassessment of in vivo thrombus formation in glycoprotein V deficient mice backcrossed on a C57Bl/6 strain

scientific article published on 05 November 2007

Reconstitution of the platelet glycoprotein Ib-IX complex in phospholipid bilayer Nanodiscs.

scientific article published on 18 November 2011

Retinoic acid receptor-α regulates synthetic events in human platelets: comment

scientific article published on 01 April 2018

Role of the leucine-rich domain of platelet GPIbalpha in correct post-translational processing--the Nancy I Bernard-Soulier mutation expressed on CHO cells

scientific article published on 01 July 2000

Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA.

scientific article

Soluble platelet glycoprotein V is a marker of thrombosis in patients with ischemic stroke

scientific article published on 03 February 2005

Spectrum of the mutations in Bernard-Soulier syndrome

scientific article

Studies of alpha 2-adrenergic receptors of intact and functional washed human platelets by binding of 3H-dihydroergocryptine and 3H-yohimbine--correlation of 3H-yohimbine binding with the potentiation by adrenaline of ADP-induced aggregation

scientific article published on 01 August 1985

Studies of mice lacking the GPIb-V-IX complex question the role of this receptor in atherosclerosis

scientific article published on 09 September 2009

Synthesis of GPIb beta with novel transmembrane and cytoplasmic sequences in a Bernard-Soulier patient resulting in GPIb-defective signaling in CHO cells.

scientific article

TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

scientific article published on 01 December 2018

Targeting platelet GPIbβ reduces platelet adhesion, GPIb signaling and thrombin generation and prevents arterial thrombosis.

scientific article

Tetraspanin CD9 is associated with very late-acting integrins in human vascular smooth muscle cells and modulates collagen matrix reorganization

scientific article published on 01 November 1998

The P2Y1 receptor plays an essential role in the platelet shape change induced by collagen when TxA2 formation is prevented

scientific article (publication date: June 2004)

The alpha(IIb)beta(3) integrin and GPIb-V-IX complex identify distinct stages in the maturation of CD34(+) cord blood cells to megakaryocytes

scientific article published on 01 December 2000

The contribution of mouse models to the understanding of constitutional thrombocytopenia

scientific article

The platelet glycoprotein GPIbbeta intracellular domain participates in von Willebrand factor induced-filopodia formation independently of the Ser 166 phosphorylation site.

scientific article published on 19 August 2009

The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells.

scientific article

Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system.

scientific article published on January 1995

Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency

scientific article published on 03 January 2006

Thrombin receptor-mediated increase of two matrix metalloproteinases, MMP-1 and MMP-3, in human endothelial cells

scientific article published on 01 October 1997

Thrombin regulates tissue factor and thrombomodulin mRNA levels and activities in human saphenous vein endothelial cells by distinct mechanisms.

scientific article published on January 1993

Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity

scientific article

[Adrenergic receptors of blood platelets]

scientific article published on 01 January 1987

[Atherothrombosis: transposition of the models to the clinic and reciprocally]

scientific article published on 01 September 2006

[Methods of studying platelet function. Biological markers of the activation of human platelets in vivo and in vitro]

scientific article published on 01 January 1986

β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function

scientific article published on 08 February 2012

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