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List of works by Valérie Gailus-Durner

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

scientific article published in May 2008

A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice

scientific article

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

scientific article

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

scientific article published on 14 February 2020

A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

article

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia

scientific article

A robust and reliable non-invasive test for stress responsivity in mice

scientific article

A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons

scientific article published on 13 February 2020

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

scientific article

Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments

scientific article

An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease

scientific article

Analysis of locomotor behavior in the German Mouse Clinic

scientific article published on 05 May 2017

Assessing Cognition in Mice

scientific article published on 2 December 2015

Blood Collection from Mice and Hematological Analyses on Mouse Blood

scientific article

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

scientific article published on 14 December 2016

CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice

scientific article

CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection

scientific article (publication date: 2016)

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

scientific article

Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms

scientific article

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

scientific article published on 6 October 2016

Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus)

scientific article published on January 2016

Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum

scientific article

Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection

scientific article published on 13 July 2009

Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets

scientific article

Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors

scientific article

Corrigendum: High-throughput discovery of novel developmental phenotypes.

scientific article published on 8 November 2017

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines

scientific article published on 11 August 2015

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

scientific article

Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation

scientific article published on 30 August 2017

Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans

scientific article published on 01 November 2020

Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice

scientific article published on 10 February 2016

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse

scientific article published on 03 May 2022

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

scientific article published on 26 June 2017

Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes

scientific journal article

Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines

scientific journal article

Dusp8 affects hippocampal size and behavior in mice and humans

scientific article published on 20 December 2019

Electroretinography as a screening method for mutations causing retinal dysfunction in mice

scientific article published in February 2004

Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

scientific article

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression

scientific article

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema

scientific article published on 13 November 2017

Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice

scientific article published on 10 July 2017

Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers

scientific article published on 8 July 2015

Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice

scientific article

Generation and characterization of dickkopf3 mutant mice

scientific article

High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans

scientific article

High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner

scientific article

High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice

scientific article published on 28 January 2015

High-throughput discovery of novel developmental phenotypes

scientific article published on 14 September 2016

High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains

scientific article published in May 2014

Human and mouse essentiality screens as a resource for disease gene discovery

scientific article published on 31 January 2020

INFRAFRONTIER: a European resource for studying the functional basis of human disease

scientific article

Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma

scientific article

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis

scientific article

In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria

scientific article published on 23 November 2019

Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

scientific article published on 27 October 2020

Innovations in phenotyping of mouse models in the German Mouse Clinic

scientific article

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.

scientific article

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification

scientific article published on 15 January 2020

Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system

scientific article

Long-term experiment to study the development, interaction, and influencing factors of DEXA parameters

scientific article

Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients

scientific article

Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice

scientific article (publication date: 2 March 2010)

METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth

scientific article published on 26 August 2020

MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation

scientific article published on 4 June 2015

MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy

scientific article

MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects

scientific article

Mechanisms controlling anaemia in Trypanosoma congolense infected mice

scientific article

Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis.

scientific article

MiR-34a deficiency accelerates medulloblastoma formation in vivo

scientific article

Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice

scientific article published on 22 December 2009

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

scientific journal article

Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.

scientific article

Modeling hepatic osteodystrophy in Abcb4 deficient mice

scientific article

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity

scientific article published on 19 September 2017

Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources

scientific article

Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

scientific article

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

scientific article published on 28 December 2020

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus

scientific article

Mouse phenotyping

scientific article

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

article

Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia

scientific article published on 10 March 2010

Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans

scientific article

Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism

scientific article published on 19 August 2009

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon

scientific article published on April 12, 2013

Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

scientific article published on 16 August 2021

Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing

scientific article

Peroxidasin is essential for eye development in the mouse

scientific article

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

scientific article published on 03 August 2013

Pleiotropic effects in Eya3 knockout mice

scientific article

Pleiotropic functions for transcription factor zscan10.

scientific article

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

scientific article

Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone

scientific article

Principles and application of LIMS in mouse clinics

scientific article (publication date: October 2015)

RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation.

scientific article

Rapamycin extends murine lifespan but has limited effects on aging

scientific article

Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice

scientific article

Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

scientific journal article

Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms

scientific article published on 2 December 2016

Sex-dependent susceptibility to Listeria monocytogenes infection is mediated by differential interleukin-10 production

scientific article

Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice

scientific article

Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss

scientific article published on 13 April 2017

Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice

scientific article

Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice

scientific article

Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 I27N mutant mice

scientific article published on 17 August 2017

Systematic gene expression profiling of mouse model series reveals coexpressed genes

scientific article published in March 2008

Systemic first-line phenotyping

scientific article published on January 2009

Tests for Anxiety-Related Behavior in Mice

scientific article published on 2 December 2015

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.

scientific article

The Role of Fibroblast Growth Factor Binding Protein 1 in Skin Carcinogenesis and Inflammation

scientific article

The endocytic adaptor Eps15 controls marginal zone B cell numbers

scientific article

The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis

scientific article

The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour

scientific journal article

The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs

scientific article published on 26 March 2020

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

scientific article

Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease

scientific article

Viable Ednra Y129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation

scientific article

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

scientific journal article