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List of works by Martin Hrabě de Angelis

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

scientific article published in May 2008

A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse

scholarly article published 19 June 2017

A Mutation in the Enamelin Gene in a Mouse Model

article

A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells

scientific article

A Myo7a mutation cosegregates with stereocilia defects and low-frequency hearing impairment

scientific journal article

A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice.

scientific article published on 28 April 2018

A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice

scientific article

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

scientific article

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

scientific article published on 14 February 2020

A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse

scientific article published on 18 December 2006

A genome-wide perspective of genetic variation in human metabolism

scientific article

A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue

scientific article published on 13 September 2017

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

scholarly article by Diana Ordoñez-Rueda et al published September 2012 in European Journal of Immunology

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

scientific article published on 12 October 2017

A mouse keratin 1 mutation causes dark skin and epidermolytic hyperkeratosis

scientific article published in May 2006

A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene

article

A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease?

scientific article published on 30 April 2009

A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

article

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia

scientific article

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity

scientific article

A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.

scientific article

A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption.

scientific article published on 23 January 2008

A polygenic risk score of lipolysis-increasing alleles determines visceral fat mass and proinsulin conversion

scientific article published on 01 April 2019

A review of standardized metabolic phenotyping of animal models

scientific article published on 09 September 2014

A robust and reliable non-invasive test for stress responsivity in mice

scientific article

A systemic view on the distribution of diet-derived methanol and hepatic acetone in mice

scientific article published on 4 September 2017

A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons

scientific article published on 13 February 2020

AMPK Subunits Harbor Largely Nonoverlapping Genetic Determinants for Body Fat Mass, Glucose Metabolism, and Cholesterol Metabolism

scientific article published on 01 January 2020

ARTS: a web-based tool for the set-up of high-throughput genome-wide mapping panels for the SNP genotyping of mouse mutants

scientific article

Abca3 haploinsufficiency is a risk factor for lung injury induced by hyperoxia or mechanical ventilation in a murine model

scientific article published on 23 July 2013

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

scientific article

Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments

scientific article

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

scientific article

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors

scientific article published on 19 July 2017

Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance

scientific article published on 23 January 2017

Alopecia in a Novel Mouse Model RCO3 Is Caused by mK6irs1 Deficiency

article

Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy

scientific article published on 01 January 2019

Amelogenesis imperfecta in a new animal model--a mutation in chromosome 5 (human 4q21)

scientific journal article

An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease

scientific article

An ENU-induced mutation in AP-2alpha leads to middle ear and ocular defects in Doarad mice

scientific article

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

scientific article

An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons

scientific article

Analysis of locomotor behavior in the German Mouse Clinic

scientific article published on 05 May 2017

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

scientific article

Androgen metabolism via 17beta-hydroxysteroid dehydrogenase type 3 in mammalian and non-mammalian vertebrates: comparison of the human and the zebrafish enzyme

scientific article

Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP.

scientific article published on 8 July 2017

Animal models of obesity and diabetes mellitus

scientific article published on 19 January 2018

Apoe, Mbl2, and Psp plasma protein levels correlate with diabetic phenotype in NZO mice--an optimized rapid workflow for SRM-based quantification

scientific article published on 12 February 2013

Applying the ARRIVE Guidelines to an In Vivo Database

scientific article

Assessing Cognition in Mice

scientific article published on 2 December 2015

Assessment of a systematic expression profiling approach in ENU-induced mouse mutant lines

scientific article

Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry

scientific article published in April 2005

Bacterial encapsulins as orthogonal compartments for mammalian cell engineering.

scientific article

Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.

scientific article

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice

scientific article published on 9 June 2016

Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice

scientific article published on 06 January 2017

Biomedical Research Goes Viral: Dangers and Opportunities

scientific article published on 11 May 2020

Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach

scientific article published on 16 July 2015

Blood Collection from Mice and Hematological Analyses on Mouse Blood

scientific article

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

scientific article published on 14 December 2016

CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice

scientific article

CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection

scientific article (publication date: 2016)

CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells

scientific article published on 11 October 2019

Calcineurin Links Mitochondrial Elongation with Energy Metabolism

scientific article

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

scientific article

Calcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation

scientific article

Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke

scholarly article by Ana I Casas et al published 18 March 2019 in Journal of Clinical Investigation

Cancer-retina antigens as potential paraneoplastic antigens in melanoma-associated retinopathy

scientific article published on January 2009

Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice

scientific article

Cardioprotection and lifespan extension by the natural polyamine spermidine.

scientific article

Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms

scientific article

Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome

scientific article

Cell-based simulation of dynamic expression patterns in the presomitic mesoderm

scientific article

Centralized mouse repositories

scientific article published on 04 September 2012

Characterization of ENU-mutant mice. Animal models for human diseases using morphological and molecular methods

scientific article published on October 2010

Characterization of a mutation in the lens-specific MP70 encoding gene of the mouse leading to a dominant cataract

scientific article published in December 2001

Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation

scientific journal article

Characterization of phospholipase C gamma enzymes with gain-of-function mutations

scientific article published on 16 June 2009

Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4.

scientific article

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

scientific article published on 6 October 2016

Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver

scientific article published on 20 March 2013

Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors

article

Claudin-12 is not required for blood-brain barrier tight junction function

scientific article published on 12 September 2019

Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus)

scientific article published on January 2016

Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum

scientific article

Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection

scientific article published on 13 July 2009

Clinical chemistry of human FcRn transgenic mice

Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

scientific article published on 16 January 2019

Combination of in silico and in situ hybridisation approaches to identify potential Dll1 associated miRNAs during mouse embryogenesis

scientific article

Combining metabolomic non-targeted GC×GC-ToF-MS analysis and chemometric ASCA-based study of variances to assess dietary influence on type 2 diabetes development in a mouse model

scientific article

Comet assay as a tool to screen for mouse models with inherited radiation sensitivity

article

Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity

scientific article

Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets

scientific article

Compartmentalised expression of Delta-like 1 in epithelial somites is required for the formation of intervertebral joints

scientific article

Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors

scientific article

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS

scientific article published on 19 June 2020

Correction: From Dynamic Expression Patterns to Boundary Formation in the Presomitic Mesoderm

scientific article published on 02 July 2019

Correction: In Vivo Functional Requirement of the Mouse Ifitm1 Gene for Germ Cell Development, Interferon Mediated Immune Response and Somitogenesis.

scientific article

Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers.

scientific article published on 17 May 2013

Corrigendum: High-throughput discovery of novel developmental phenotypes.

scientific article published on 8 November 2017

Costs of Implementing Quality in Research Practice

scientific article published on 01 January 2020

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines

scientific article published on 11 August 2015

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice

Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function

scientific article

Cryopreservation of mouse spermatozoa: double your mouse space.

scientific article

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

scientific article

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

scientific article

Cytokine response of primary human myotubes in an in vitro exercise model

scientific article published on 7 August 2013

Cytoplasmic mislocalization of POU3F4 due to novel mutations leads to deafness in humans and mice

scientific article

DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments

scientific article

DLL1- and DLL4-Mediated Notch Signaling is Essential for Adult Pancreatic Islet Homeostasis

scientific article published on 06 February 2020

Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation

scientific article published on 30 August 2017

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.

scientific article published on 13 April 2018

Deletion of glucose transporter GLUT8 in mice increases locomotor activity

scientific article published on 7 May 2008

Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process

scientific article published on 01 April 2003

Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring

scientific article published on 11 December 2015

Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects

scientific article published on 04 December 2007

Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans

scientific article published on 01 November 2020

Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice

scientific article published on 10 February 2016

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse

scientific article published on 03 May 2022

Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue-Multi-omics Insights From the Munich MIDY Pig Model

scientific article published on 23 November 2021

Differential effects of neurofibromin gene dosage on melanocyte development

scientific article

Dilution correction for dynamically influenced urinary analyte data

scientific article published on 28 July 2018

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

scientific article published on 20 February 2013

Discovery of a novel enzyme mediating glucocorticoid catabolism in fish: 20beta-hydroxysteroid dehydrogenase type 2.

scientific article published on 28 October 2011

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

scientific article published on 26 June 2017

Distinct regulatory elements direct delta1 expression in the nervous system and paraxial mesoderm of transgenic mice

scientific article published in July 2000

Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet

scientific article

Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes

scientific journal article

Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines

scientific journal article

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression

scientific journal article

Dose-dependent long-term effects of a single radiation event on behaviour and glial cells

scientific article published on 02 December 2020

Dusp8 affects hippocampal size and behavior in mice and humans

scientific article published on 20 December 2019

EGFR ligands exert diverging effects on male reproductive organs

EMMA--mouse mutant resources for the international scientific community

scientific article

EMMA--the European mouse mutant archive

scientific article

ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta

scientific article

Ectopic fat accumulation in human astrocytes impairs insulin action

scientific article published on 16 September 2020

Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes

scientific article

Effects of ENU dosage on mouse strains

article

Effects of G-protein mutations on skin color

scientific journal article

Effects of diet-matrix on volatile organic compounds in breath in diet-induced obese mice

article

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

scientific article published on 5 August 2015

Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads

scientific article

Electroretinography as a screening method for mutations causing retinal dysfunction in mice

scientific article published in February 2004

Emergency prevention of extinction of a transgenic allele in a less-fertile transgenic mouse line by crossing with an inbred or outbred mouse strain coupled with assisted reproductive technologies

scientific article

Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

scientific article published on 31 January 2020

Endothelial amine oxidase AOC3 transiently contributes to adaptive immune responses in the airways

scientific article published on 8 September 2014

Enhanced oxidative stress and endocrine pancreas alterations are linked to a novel glucokinase missense mutation in ENU-derived Munich Gck(D217V) mutants

scientific journal article

Enu mouse mutagenesis: generation of mouse mutants with aberrant plasma IgE levels

scientific article published in January 2001

Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice

scientific article

Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.

scientific article published on 21 February 2018

Epigenetic germline inheritance of diet-induced obesity and insulin resistance.

scientific article

Epigenetische Vererbung – Ist die Zukunft diabetisch?

article

Ernährungsgewohnheiten schlagen sich im Erbgut nieder

Erratum to: High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice

scientific article published on 01 August 2015

Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts

scientific article published on 07 March 2019

Erratum: Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

scientific article published on 26 May 2016

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Establishing sample-preparation protocols for X-ray phase-contrast CT of rodent spinal cords: Aldehyde fixations and osmium impregnation

scientific article published on 27 April 2020

Eukaryotically expressed encapsulins as orthogonal compartments for multiscale molecular imaging

EuroPhenome: a repository for high-throughput mouse phenotyping data

scientific article

Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

scientific article

Ex-vivo assessment and non-invasive in vivo imaging of internal hemorrhages in Aga2/+ mutant mice

scientific article published on 18 January 2013

Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability

scientific article published on 22 October 2021

Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.

scientific article published on 23 January 2016

Expression of Tas1 Taste Receptors in Mammalian Spermatozoa: Functional Role of Tas1r1 in Regulating Basal Ca2+ and cAMP Concentrations in Spermatozoa ⬇️

scientific article published on February 29, 2012

Expression of the mouse Delta1 gene during organogenesis and fetal development

scientific article (publication date: June 1999)

Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice

scientific article published on 18 December 2008

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression

scientific article

FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography

scientific article

Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia

scientific article published on 8 January 2018

Fast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition

scientific article

Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema

scientific article published on 13 November 2017

Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice

scientific article published on 10 July 2017

Fibroblast Growth Factor 21-Metabolic Role in Mice and Men.

scientific article published on 28 July 2017

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

scientific article published on May 2015

Fibroblast growth factor induces primitive streak formation in rabbit pre-implantation embryos in vitro

scientific article published in March 1993

First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts

scientific journal article

From dynamic expression patterns to boundary formation in the presomitic mesoderm

scientific article published in 2012

Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers

scientific article published on 8 July 2015

Functional genome analysis indicates loss of 17beta-hydroxysteroid dehydrogenase type 2 enzyme in the zebrafish

scientific article published on 7 November 2006

Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype

scientific journal article

Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans

scientific article published on 28 May 2019

Gender-, strain-, and inheritance-dependent variation in aldosterone secretion in mice

scientific article published on 26 September 2012

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases

scientific article

Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice

scientific article

Generation and characterization of dickkopf3 mutant mice

scientific article

Generation of ENU-Induced Mouse Mutants with Hypocholesterolemia: Novel Tools for Dissecting Plasma Lipoprotein Homeostasis

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters

scientific article published on 8 May 2011

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models

scientific article published on 16 January 2009

Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review.

scientific article published on 22 May 2018

Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review

article

Genetic and molecular insights into genotype-phenotype relationships in osteopathia striata with cranial sclerosis (OSCS) through the analysis of novel mouse Wtx mutant alleles

scientific article published on 12 January 2018

Genetic characterization of a mouse line with primary aldosteronism

scientific article published on 13 December 2016

Genetically Controlled Lysosomal Entrapment of Superparamagnetic Ferritin for Multimodal and Multiscale Imaging and Actuation with Low Tissue Attenuation

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

scientific article

Genetics of dark skin in mice

scientific article

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors

scientific article published on 30 January 2018

Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice

scientific article published on 24 February 2009

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

scientific article

Genomewide Linkage Analysis Identifies Novel Genetic Loci for Lung Function in Mice

article

Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over

scientific article published on 6 May 2015

Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice

scientific article published on 7 February 2006

Glucose Tolerance Tests for Systematic Screening of Glucose Homeostasis in Mice

Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity

scientific article published on 19 September 2018

Great times for mouse genetics: getting ready for large-scale ENU-mutagenesis

article

Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies

scientific article published on 25 November 2020

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver

scientific article published on 15 March 2018

Gsdma3I359N is a novel ENU-induced mutant mouse line for studying the function of Gasdermin A3 in the hair follicle and epidermis

Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile Dysfunction in the Aging Myocardium

scientific article

Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity

scientific article published on 14 October 2019

Heritable translocations induced by dermal exposure of male mice to acrylamide

scientific article published on January 2004

High Performance Proteomics: 7th HUPO Brain Proteome Project Workshop March 7-9, 2007 Wellcome Trust Conference Centre, Hinxton, UK.

scientific article published in August 2007

High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice

scientific article

High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans

scientific article

High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner

scientific article

High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice

scientific article published on 28 January 2015

High-throughput discovery of genetic determinants of circadian misalignment

scientific article published on 13 January 2020

High-throughput discovery of novel developmental phenotypes

scientific article published on 14 September 2016

High-throughput extraction and quantification method for targeted metabolomics in murine tissues.

scientific article published on 30 December 2017

High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains

scientific article published in May 2014

Huge splicing frequency in human Y chromosomal UTY gene

scientific article published on 17 February 2011

Human and mouse essentiality screens as a resource for disease gene discovery

scientific article published on 31 January 2020

Human metabolic individuality in biomedical and pharmaceutical research

scientific article (publication date: 31 August 2011)

Hush puppy: a new mouse mutant with pinna, ossicle, and inner ear defects

scientific journal article

Hypercholesterolemia in ENU-induced mouse mutants

scientific article published in September 2004

Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease.

scientific article published on 9 September 2016

INFRAFRONTIER: a European resource for studying the functional basis of human disease

scientific article

Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis

scientific article

Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling

scientific article

Identification of a Keratin 4 mutation in a chemically induced mouse mutant that models white sponge nevus

scientific article

Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in preclinical drug testing

scientific article published on 4 May 2011

Identification of biomarkers for apoptosis in cancer cell lines using metabolomics: tools for individualized medicine

scientific article published on November 2013

Identification of genes required for eye development by high-throughput screening of mouse knockouts

scientific article published on 21 December 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

scientific article published on 18 January 2018

Identification of immunological relevant phenotypes in ENU mutagenized mice

scholarly article by Heinrich Flaswinkel et al published July 2000 in Mammalian Genome

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

scientific article published on 4 October 2012

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.

scientific article

Impact of Brain Fatty Acid Signaling on Peripheral Insulin Action in Mice

scholarly article by Susanne Neschen et al published 5 November 2018 in Experimental and Clinical Endocrinology and Diabetes

Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice

scientific article published in March 2007

Impact of fibroblast growth factor 21 on the secretome of human perivascular preadipocytes and adipocytes: a targeted proteomics approach

scientific article published on 5 August 2016

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

scientific article

Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation

scientific article

Importance of sulfur-containing metabolites in discriminating fecal extracts between normal and type-2 diabetic mice

scholarly article by Alesia Walker et al published 2 September 2014 in Journal of Proteome Research

Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma

scientific article

In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system

article

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis

scientific article

In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria

scientific article published on 23 November 2019

Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

scientific article published on 27 October 2020

Increased mitochondrial respiration of adipocytes from metabolically unhealthy obese compared to healthy obese individuals

scientific article published on 24 July 2020

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

scientific article published on 04 November 2020

Innovations in phenotyping of mouse models in the German Mouse Clinic

scientific article

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse

scientific article published on 01 May 1999

Interaction of the MAGUK family member Acvrinp1 and the cytoplasmic domain of the Notch ligand Delta1

scientific journal article

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.

scientific article

Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids

scientific article

Introducing the German Mouse Clinic: open access platform for standardized phenotyping.

scientific article

Iopromide exposure in Typha latifolia L.: Evaluation of uptake, translocation and different transformation mechanisms in planta

scientific article published on 4 June 2017

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification

scientific article published on 15 January 2020

Isolation and characterization of a novel gene from the DiGeorge chromosomal region that encodes for a mediator subunit

scientific article (publication date: 15 June 2001)

KIT is required for hepatic function during mouse post-natal development

scientific article

Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis

Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.

scientific article

Large scale ENU screens in the mouse: genetics meets genomics

scientific article published on May 1998

Large-Scale N -Ethyl-N -Nitrosourea Mutagenesis of Mice - from Phenotypes to Genes

article

Large-scale albuminuria screen for nephropathy models in chemically induced mouse mutants

scientific article published on 20 April 2005

Large-scale mutational analysis for the annotation of the mouse genome

scientific article

Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system

scientific article

Lens density tracking in mice by Scheimpflug imaging

scientific article published on 9 August 2013

Ligand-independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice

scientific article published in October 2013

LitMiner and WikiGene: identifying problem-related key players of gene regulation using publication abstracts

scientific article

Liver adapts mitochondrial function to insulin resistant and diabetic states in mice

scientific article published on 28 November 2013

Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse

scientific article published on 9 December 2015

Long-term experiment to study the development, interaction, and influencing factors of DEXA parameters

scientific article

Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients

scientific article

Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice

scientific article published on 4 February 2016

Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains

scientific article

Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling

scientific article published on 13 December 2014

Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors

scientific article

Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice

scientific article (publication date: 2 March 2010)

Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase (TPI) deficiency

scientific article published on 11 June 2019

MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults

scientific article

METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth

scientific article published on 26 August 2020

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation

scientific article published on 12 November 2015

MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation

scientific article published on 4 June 2015

MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention

scientific article

MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy

scientific article

Machine Learning Approaches Revealed Metabolic Signatures of Incident Chronic Kidney Disease in Persons With Pre-and Type 2 Diabetes

scientific article published on 06 October 2020

Maintenance of somite borders in mice requires the Delta homologue DII1.

scientific article

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood

scientific article published on 10 September 2018

Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin

scientific article

MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects

scientific article

Measuring and Interpreting Oxygen Consumption Rates in Whole Fly Head Segments

scientific article published on 07 January 2019

Mechanisms controlling anaemia in Trypanosoma congolense infected mice

scientific article

Meis1 coordinates a network of genes implicated in eye development and microphthalmia

scientific article published on 7 August 2015

Meis1: effects on motor phenotypes and the sensorimotor system in mice

scientific article published on 23 June 2017

Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase

article

Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis.

scientific article

Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting

scientific article (publication date: 11 November 2010)

Metabolic phenotyping of mouse mutants in the German Mouse Clinic

article

Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese individuals

scientific article

Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.

scientific article published on 23 September 2015

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs

scientific article published on 28 June 2018

Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues

scientific article published on 12 September 2016

Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state

scientific article published on 5 May 2017

Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice

scientific article published on 28 July 2014

Methods for Proteomics-Based Analysis of the Human Muscle Secretome Using an In Vitro Exercise Model

article

MiR-34a deficiency accelerates medulloblastoma formation in vivo

scientific article

Micro-imaging of Brain Cancer Radiation Therapy Using Phase-contrast Computed Tomography

scientific article published on 07 April 2018

Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma

scientific article published on 2 June 2015

Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice

scientific article published on 22 December 2009

Mild maternal hyperglycemia in INS C93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring

scientific article published on 12 August 2019

Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice

scientific article published in February 2016

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

scientific journal article

Mitochondrial Function, Dysfunction, and Adaptation in the Liver during the Development of Diabetes

article

Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.

scientific article

Mitochondrial glutathione peroxidase 4 disruption causes male infertility

scientific article

Modeling coexistence of oscillation and Delta/Notch-mediated lateral inhibition in pancreas development and neurogenesis

scientific article published on 23 June 2017

Modeling disease mutations by gene targeting in one-cell mouse embryos

scientific article

Modeling hepatic osteodystrophy in Abcb4 deficient mice

scientific article

Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice

scientific article

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon

scientific journal article

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity

scientific article published on 19 September 2017

Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy

scientific article published on 3 August 2011

Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71 rco12 and Krt71 rco13

Mouse Age Matters: How Age Affects the Murine Plasma Metabolome

scientific article published on 19 November 2020

Mouse Genetics and Metabolic Mouse Phenotyping

article

Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources

scientific article

Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

scientific article

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

scientific article published on 28 December 2020

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus

scientific article

Mouse phenotyping

scientific article

MouseNet database: digital management of a large-scale mutagenesis project

scientific article published on July 2000

Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36.

scientific article

Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality

scientific article published on 05 September 2019

Mutation in Bmpr1b Leads to Optic Disc Coloboma and Ventral Retinal Gliosis in Mice

scientific article published on 01 February 2020

Mutation in a novel connexin-like gene (Gjf1) in the mouse affects early lens development and causes a variable small-eye phenotype

scientific journal article

Mutation in the betaA3/A1-crystallin encoding gene Cryba1 causes a dominant cataract in the mouse

scientific article (publication date: 15 November 1999)

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia

article

Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia

scientific article published on 10 March 2010

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

scientific article published in Science

Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

scientific article

N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes

scientific article published on June 2017

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels

scientific article published on 08 June 2009

Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis.

scientific article published in February 2012

Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans

scientific article

Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import

article

Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord

scientific article published on 16 August 2018

Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.

scientific article

Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress

scientific article

New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse

New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis

scientific article

New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts

scientific article published on 7 May 2015

Night Shift Work Affects Urine Metabolite Profiles of Nurses with Early Chronotype

scholarly article by Markus Rotter published in August 2018

No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.

scientific article

Node and midline defects are associated with left-right development in Delta1 mutant embryos.

scientific article published in January 2003

Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.

scientific article published on 11 December 2017

Novel biomarkers for pre-diabetes identified by metabolomics

scientific article

Novel lymphocyte-independent mechanisms to initiate inflammatory arthritis via bone marrow-derived cells of Ali18 mutant mice

scientific article published on 01 March 2008

Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism

scientific article published on 19 August 2009

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon ⬇️

scientific article published on April 12, 2013

Number of active transcription factor binding sites is essential for the Hes7 oscillator

scientific article

Nutrition and its role in epigenetic inheritance of obesity and diabetes across generations

scientific article published on 30 April 2020

Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

scientific article published on 16 August 2021

Online breath gas analysis in unrestrained mice by hs-PTR-MS.

scientific article

Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors

scientific journal article

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice.

scientific article

Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study.

scientific article published on 03 February 2009

Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms

scientific article

Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing

scientific article

Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice

scientific article

PATHBIO: an international training program for precision mouse phenotyping

scientific article published on 22 February 2020

PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance

scientific article published on 30 October 2020

Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes

scientific article published on 04 January 2021

Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring.

scientific article

Peroxidasin is essential for eye development in the mouse

scientific article

Pharmacogenetics of oral antidiabetic therapy

Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2).

scientific article published in December 2009

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

scientific article published on 03 August 2013

Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice

scientific article published on 25 June 2020

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb

scientific article published on 11 January 2012

Pleiotropic effects in Eya3 knockout mice

scientific article

Pleiotropic functions for transcription factor zscan10.

scientific article

Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance

scientific article published on 18 July 2017

Post-publication sharing of data and tools

scientific article

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

scientific article

Power matters in closing the phenotyping gap.

scientific article

Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone

scientific article

Prdm6 is essential for cardiovascular development in vivo

scientific article

Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin

article

Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test.

scientific article published on 19 March 2018

Prevalence of sexual dimorphism in mammalian phenotypic traits

scientific article

Principles and application of LIMS in mouse clinics

scientific article (publication date: October 2015)

Production and release of acylcarnitines by primary myotubes reflect the differences in fasting fat oxidation of the donors

scientific article published on 30 April 2013

Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice

scientific article

Promotion of gastrulation by maternal growth factor in cultured rabbit blastocysts

scientific article published in October 1995

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

scientific article published on 22 December 2020

RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure

scientific article published on 07 August 2018

RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation.

scientific article

Rapamycin extends murine lifespan but has limited effects on aging

scientific article

Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue

scientific article published on 8 March 2018

Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.

scientific article

Reliable recovery of inbred mouse lines using cryopreserved spermatozoa.

scientific article published on August 1999

Removing the bottlenecks of cell culture metabolomics: fast normalization procedure, correlation of metabolites to cell number, and impact of the cell harvesting method

scientific article published on 15 September 2016

Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice

scientific article

Research funding. Sustaining the data and bioresource commons

scientific article

Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

scientific journal article

Retinal proteome alterations in a mouse model of type 2 diabetes

scientific article published on January 2014

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

scientific article published on 20 July 2008

Risk assessment of mouse hepatitis virus infection via in vitro fertilization and embryo transfer by the use of zona-intact and laser-microdissected oocytes

scientific article published on 12 October 2005

Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells

scientific article

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities

scientific article published on 18 March 2013

Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo

scientific article published on September 2008

Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels

scientific article published in 2015

Screening for dysmorphological abnormalities—a powerful tool to isolate new mouse mutants

article published in 2000

Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models

scientific journal article

Secretome profiling of primary human skeletal muscle cells

scientific article published on 27 August 2013

Selection and evaluation of stable housekeeping genes for gene expression normalization in carbon nanoparticle-induced acute pulmonary inflammation in mice ⬇️

scientific article published on September 3, 2010

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Sequence interpretation. Functional annotation of mouse genome sequences

scientific article

Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms

scientific article published on 2 December 2016

Sex-dependent susceptibility to Listeria monocytogenes infection is mediated by differential interleukin-10 production

scientific article

Smad-interacting protein 1 affects acute and tonic, but not chronic pain

scientific article published on 17 July 2013

Specific CD8 T cells in IgE-mediated allergy correlate with allergen dose and allergic phenotype

scientific article published on 8 October 2009

Specificity assessment from fractionation experiments (SAFE): a novel method to evaluate microarray probe specificity based on hybridisation stringencies

scientific article

Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses

scientific article published on 18 November 2019

Sperm cryopreservation and in vitro fertilization

scientific article published on January 2009

Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice

scientific article

Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss

scientific article published on 13 April 2017

Srgap3⁻/⁻ mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes

scientific article published on 20 July 2012

Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice

scientific article

Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice

scientific article

Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 I27N mutant mice

scientific article published on 17 August 2017

Steroids in teleost fishes: A functional point of view

scientific article published on 20 June 2015

Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain

scientific article published in Scientific Reports

Structural and functional concepts in current mouse phenotyping and archiving facilities ⬇️

scientific article published on July 1, 2012

Systematic gene expression profiling of mouse model series reveals coexpressed genes

scientific article published in March 2008

Systematic phenotyping of mouse mutants

Systematic selection of housekeeping genes for gene expression normalization in chicken embryo fibroblasts infected with Newcastle disease virus

scientific article published on 6 September 2011

Systematic, standardized and comprehensive neurological phenotyping of inbred mice strains in the German Mouse Clinic

scientific article published on 23 May 2006

Systemic first-line phenotyping

scientific article published on January 2009

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle

scientific article published on 29 June 2016

Tailchaser (Tlc): a new mouse mutation affecting hair bundle differentiation and hair cell survival.

scientific article published in October 1999

Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality

scientific journal article

Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function

scientific journal article

Targeted estrogen delivery reverses the metabolic syndrome

scientific article

Targeted inactivation of the murine Abca3 gene leads to respiratory failure in newborns with defective lamellar bodies

article

Tests for Anxiety-Related Behavior in Mice

scientific article published on 2 December 2015

The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing

scientific article published on 11 September 2017

The C-terminal cytoplasmic domain of human proEGF is a negative modulator of body and organ weights in transgenic mice

scientific article published on 27 March 2009

The CALM and CALM/AF10 interactor CATS is a marker for proliferation

scientific article published on 4 September 2008

The Deep Genome Project

scientific article published on 03 February 2020

The European dimension for the mouse genome mutagenesis program

scientific article

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.

scientific article

The German Mouse Clinic – Running an Open Access Platform

article

The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.

scientific article

The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation

scientific article published on 19 May 2018

The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes

scientific article

The Notch ligand Jagged1 is required for inner ear sensory development.

scholarly article

The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks ⬇️

scientific article published in November 2017

The Role of Fibroblast Growth Factor Binding Protein 1 in Skin Carcinogenesis and Inflammation

scientific article

The biochemical metabolite screen in the Munich ENU Mouse Mutagenesis Project: determination of amino acids and acylcarnitines by tandem mass spectrometry

The chemotherapeutic agents nocodazole and amsacrine cause meiotic delay and non-disjunction in spermatocytes of mice

scientific article published on 4 November 2007

The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypes

article by Birgit Rathkolb et al published July 2000 in Mammalian Genome

The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells

scientific article

The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk

scientific article published on 05 May 2018

The endocytic adaptor Eps15 controls marginal zone B cell numbers

scientific article

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis

scientific article

The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?

article

The impact of blood on liver metabolite profiling – a combined metabolomic and proteomic approach ⬇️

scientific article published on August 12, 2013

The large-scale Munich ENU-mouse-mutagenesis screen

The mammalian gene function resource: the International Knockout Mouse Consortium

scientific article

The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour

scientific journal article

The novel mouse microphthalmia mutations Mitfmi-enu5 and Mitfmi-bcc2 produce dominant negative Mitf proteins

scientific article published in May 2004

The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss

scientific article

The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities

scientific article published on 15 June 2020

The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth

scientific journal article

The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs

scientific article published on 26 March 2020

The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes

scientific article published on 13 March 2017

The transcription factor Smad-interacting protein 1 controls pain sensitivity via modulation of DRG neuron excitability

Three novel Pax6 alleles in the mouse leading to the same small-eye phenotype caused by different consequences at target promoters

scientific article published on December 2005

Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling

scientific article published on June 2009

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

article

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

scientific article

Transcriptional regulation of human and murine 17beta-hydroxysteroid dehydrogenase type-7 confers its participation in cholesterol biosynthesis

scientific article

Transcriptome and proteome analysis of early embryonic mouse brain development

scientific article published in March 2008

Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery

scientific article published on 12 June 2015

Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

scientific article published on 11 August 2020

Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice

scientific article published on 6 June 2013

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic

scientific article

Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease

scientific article

Use of chemical mutagenesis in mouse embryonic stem cells

scientific article published on January 2006

Utilization of a mutagenesis screen to generate mouse models of hyperaldosteronism

scientific article

V76D mutation in a conserved gD-crystallin region leads to dominant cataracts in mice

scientific article published on 01 August 2002

Variation of the response to the optokinetic drum among various strains of mice

scientific article published in May 2008

Variations of eye size parameters among different strains of mice

scientific article published on 4 August 2006

Viable Ednra Y129F mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation

scientific article

Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

scientific article published in October 2012

Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests

scientific article

Vom Labor zum Patienten – Translationale Diabetesforschung

Zebrafish 20β-Hydroxysteroid Dehydrogenase Type 2 Is Important for Glucocorticoid Catabolism in Stress Response ⬇️

scientific article published on January 22, 2013

Zebrafish and steroids: what do we know and what do we need to know?

scientific article published on 30 January 2013

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription

scientific journal article

hIAPP forms toxic oligomers in plasma

article

iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis

scientific article published on 01 March 2020

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