List of works - Lukas Sommer

A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors

scientific article (publication date: 2013)

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.

scientific article

Chemokines in neuroectodermal development and their potential implication in cancer stem cell-driven metastasis.

scientific article

Coexpression of SOX10/CD271 (p75(NTR)) and β-Galactosidase in Large to Giant Congenital Melanocytic Nevi of Pediatric Patients.

scientific article published on January 2014

Context-dependent regulation of fate decisions in multipotent progenitor cells of the peripheral nervous system.

scientific article

Cre-driver lines used for genetic fate mapping of neural crest cells in the mouse: An overview

scientific article published on 19 April 2018

Development of the Schwann cell lineage: from the neural crest to the myelinated nerve

scientific article

Developmental Biology of Melanocytes

scientific article

DiGeorge syndrome and pharyngeal apparatus development

scientific article published on November 2006

Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation

scientific article published on 11 April 2015

EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation

scientific article published on 28 June 2018

Engineering melanoma progression in a humanized environment in vivo.

scientific article published in September 2011

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

scientific article published on 20 August 2021

Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis

scientific article published on 23 March 2007

Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells

scientific article published on 13 November 2017

Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model

scientific article

Generation of melanocytes from neural crest cells.

scientific article published on 08 March 2011

Growth factors regulating neural crest cell fate decisions.

scientific article published on January 2006

Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

scientific article

In Vitro Derivation of Melanocytes from Embryonic Neural Crest Stem Cells

scientific article published on 13 December 2015

In vivo tumorigenesis was observed after injection of in vitro expanded neural crest stem cells isolated from adult bone marrow

scientific article

Injury and stress responses of adult neural crest-derived cells

scientific article published on 17 May 2018

Injury-activated glial cells promote wound healing of the adult skin in mice

scientific article published on 16 January 2018

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation

scientific article published on 30 November 2015

MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory neural crest cells

scientific article (publication date: June 1997)

Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells.

scientific article published in June 2002

Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences

scientific article published on 19 February 2012

Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

scientific article

Multiple lineage-specific roles of Smad4 during neural crest development

scientific article published on 8 April 2009

Multiple roles of mouse Numb in tuning developmental cell fates.

scientific article published in April 2001

NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence

scientific article published on 04 August 2021

Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin

scientific article

Neural crest-derived stem cells

scientific article published on 9 July 2010

Neural stem cells and regulation of cell number

scientific article

Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system

scientific journal article

Notch signalling controls pancreatic cell differentiation

scientific journal article

Open questions: development of tumor cell heterogeneity and its implications for cancer treatment.

scientific article

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural stem cell specification into oligodendrocytes and glutamatergic neurons

scientific article published in May 2014

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells

scientific journal article

Premigratory and migratory neural crest cells are multipotent in vivo

scientific article

Publisher Correction: The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma

scientific article

Quo vadis: tracing the fate of neural crest cells

scientific article

RPTP delta and the novel protein tyrosine phosphatase RPTP psi are expressed in restricted regions of the developing central nervous system

scientific article

Rare, yet relevant tumor cells - A new twist to melanoma cell plasticity

scientific article published on 12 September 2017

Reemergence of neural crest stem cell-like states in melanoma during disease progression and treatment

scientific article published on 01 December 2020

Reinventing the neural crest: direct reprogramming makes iNCCs

scientific article published on 01 October 2014

SMAD signaling promotes melanoma metastasis independently of phenotype switching

scientific article published on 30 April 2019

Smad4 and Trim33/Tif1γ redundantly regulate neural stem cells in the developing cortex.

scientific article published on 13 June 2013

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

scientific article

Sox5 and chromatophores: switching pigment cell fates

scientific article published on 12 August 2014

Stage- and area-specific control of stem cells in the developing nervous system.

scientific article published on 10 September 2009

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

scientific article published in March 2009

Stem Cells

scientific article

TGF beta signaling in neural crest cells in development and diseases

scientific article

Testing the cancer stem cell hypothesis in melanoma: the clinics will tell

scientific article published on 13 October 2012

The cellular function of MASH1 in autonomic neurogenesis

scientific journal article

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.

scientific article

The glycoprotein P0 in peripheral gliogenesis ⬇️

scientific article published on April 1, 1998

The neural crest: understanding stem cell function in development and disease

scientific article published on January 2007

The protooncogene Ski controls Schwann cell proliferation and myelination

scientific article

The role of the Ets domain transcription factor Erm in modulating differentiation of neural crest stem cells

scientific journal article

Transforming growth factor β-mediated Sox10 suppression controls mesenchymal progenitor generation in neural crest stem cells

scientific article published on April 2011

Tumor cell plasticity and angiogenesis in human melanomas

scientific article

Versican V0 and V1 guide migratory neural crest cells.

scientific article published in March 2006

Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells

scientific article

Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells

scientific article published in January 2015

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

scientific article published on 01 April 2019

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

article

low neurotrophin receptor CD271 regulates phenotype switching in melanoma

scientific article published on 7 December 2017

List of works by Lukas Sommer

A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.

Chemokines in neuroectodermal development and their potential implication in cancer stem cell-driven metastasis.

Coexpression of SOX10/CD271 (p75(NTR)) and β-Galactosidase in Large to Giant Congenital Melanocytic Nevi of Pediatric Patients.

Context-dependent regulation of fate decisions in multipotent progenitor cells of the peripheral nervous system.

Cre-driver lines used for genetic fate mapping of neural crest cells in the mouse: An overview

Development of the Schwann cell lineage: from the neural crest to the myelinated nerve

Developmental Biology of Melanocytes

DiGeorge syndrome and pharyngeal apparatus development

Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation

EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation

Engineering melanoma progression in a humanized environment in vivo.

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis

Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells

Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model

Generation of melanocytes from neural crest cells.

Growth factors regulating neural crest cell fate decisions.

Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

In Vitro Derivation of Melanocytes from Embryonic Neural Crest Stem Cells

In vivo tumorigenesis was observed after injection of in vitro expanded neural crest stem cells isolated from adult bone marrow

Injury and stress responses of adult neural crest-derived cells

Injury-activated glial cells promote wound healing of the adult skin in mice

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation

MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory neural crest cells

Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells.

Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences

Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

Multiple lineage-specific roles of Smad4 during neural crest development

Multiple roles of mouse Numb in tuning developmental cell fates.

NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence

Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin

Neural crest-derived stem cells

Neural stem cells and regulation of cell number

Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system

Notch signalling controls pancreatic cell differentiation

Open questions: development of tumor cell heterogeneity and its implications for cancer treatment.

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural stem cell specification into oligodendrocytes and glutamatergic neurons

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells

Premigratory and migratory neural crest cells are multipotent in vivo

Publisher Correction: The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma

Quo vadis: tracing the fate of neural crest cells

RPTP delta and the novel protein tyrosine phosphatase RPTP psi are expressed in restricted regions of the developing central nervous system

Rare, yet relevant tumor cells - A new twist to melanoma cell plasticity

Reemergence of neural crest stem cell-like states in melanoma during disease progression and treatment

Reinventing the neural crest: direct reprogramming makes iNCCs

SMAD signaling promotes melanoma metastasis independently of phenotype switching

Smad4 and Trim33/Tif1γ redundantly regulate neural stem cells in the developing cortex.

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

Sox5 and chromatophores: switching pigment cell fates

Stage- and area-specific control of stem cells in the developing nervous system.

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

Stem Cells

TGF beta signaling in neural crest cells in development and diseases

Testing the cancer stem cell hypothesis in melanoma: the clinics will tell

The cellular function of MASH1 in autonomic neurogenesis

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.

The glycoprotein P0 in peripheral gliogenesis ⬇️

The neural crest: understanding stem cell function in development and disease

The protooncogene Ski controls Schwann cell proliferation and myelination

The role of the Ets domain transcription factor Erm in modulating differentiation of neural crest stem cells

Transforming growth factor β-mediated Sox10 suppression controls mesenchymal progenitor generation in neural crest stem cells

Tumor cell plasticity and angiogenesis in human melanomas

Versican V0 and V1 guide migratory neural crest cells.

Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells

Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

low neurotrophin receptor CD271 regulates phenotype switching in melanoma