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List of works by Ueli Suter

A new missense GDAP1 mutation disturbing targeting to the mitochondrial membrane causes a severe form of AR-CMT2C disease

scientific article published on 02 March 2011

AFM combines functional and morphological analysis of peripheral myelinated and demyelinated nerve fibers.

scientific article published on 16 June 2007

An animal model for Charcot-Marie-Tooth disease type 4B1.

scientific article published on 25 October 2005

Analysis of neural crest-derived clones reveals novel aspects of facial development

scientific article

Antigens expressed by myelinating glia cells induce peripheral cross-tolerance of endogenous CD8+ T cells.

scientific article

Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.

scientific article

Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

scientific article

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

scientific article published in July 2006

Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion

scientific article published in May 2008

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

scientific article published on 07 May 2019

CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

scientific article

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS

scientific article published on 01 October 2006

Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation.

scientific article

Cell-intrinsic and cell-extrinsic cues regulating lineage decisions in multipotent neural crest-derived progenitor cells.

scientific article published in January 2002

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission.

scientific article published on 30 April 2013

Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells

scientific article

Conduction block in PMP22 deficiency.

scientific article published on January 2010

De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination.

scientific article published on 6 February 2018

Dicer in Schwann cells is required for myelination and axonal integrity

scientific journal article

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain

scientific journal article

Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point mutation

scientific article

Distinct elements of the peripheral myelin protein 22 (PMP22) promoter regulate expression in Schwann cells and sensory neurons

scientific article published on 01 November 2003

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

scientific journal article

Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

scientific article published on 7 September 2017

Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination

scientific article published on 26 March 2012

E-cadherin Is Required for the Correct Formation of Autotypic Adherens Junctions of the Outer Mesaxon but Not for the Integrity of Myelinated Fibers of Peripheral Nerves

scientific article published on 01 October 2002

E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles

scientific article

Early neuronal and glial fate restriction of embryonic neural stem cells

scientific article published on 01 March 2008

Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells.

scientific article published in March 2004

Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

scientific article published in June 2010

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.

scientific article published in February 2006

Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development

scientific article

Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom

scientific article published on 01 November 2004

Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle

scientific article published on August 2008

FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35.

scientific article published on July 2005

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance.

scientific article published on 25 September 2009

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

scientific article

Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system

scientific article published in April 2010

Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.

scientific article published in January 2011

Glial origin of mesenchymal stem cells in a tooth model system

scientific article published on 27 July 2014

Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain

scientific article

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

scientific article

HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.

scientific article published on April 2014

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells

scientific article published on 20 March 2011

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

scientific article

How Histone Deacetylases Control Myelination ⬇️

scientific article published on August 23, 2011

Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves

scientific article published in May 2002

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

scientific article

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

article

Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

scientific article

Injury-activated glial cells promote wound healing of the adult skin in mice

scientific article published on 16 January 2018

Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells

scientific article published on 08 January 2004

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

scientific journal article

Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia

scientific article published in January 2006

Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal.

scientific article

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

scientific article published on 18 November 2004

LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: Implications for Charcot‐Marie‐Tooth disease ⬇️

scientific article published on June 21, 2012

Lineage-specific requirements of beta-catenin in neural crest development

scientific article

Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1.

scientific article

MRI signature in a novel mouse model of genetically induced adult oligodendrocyte cell death.

scientific article

Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module ⬇️

scientific article published on October 6, 2003

Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells.

scientific article published in June 2002

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

scientific article published on 2 December 2012

Mice carrying an analogous heterozygous Dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy

scientific article published on 04 March 2020

Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush

scientific journal article

Molecular Biology of Axon–Glia Interactions in the Peripheral Nervous System1

scholarly article by Verdon Taylor published in January 1997

Molecular cell biology of Charcot-Marie-Tooth disease.

scientific article

Molecular mechanisms regulating myelination in the peripheral nervous system ⬇️

scientific article published on December 21, 2011

Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2

scientific article published on 12 September 2007

Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

scientific journal article

Murine numb regulates granule cell maturation in the cerebellum

scientific article

Muscle-specific function of the centronuclear myopathy and Charcot–Marie–Tooth neuropathy-associated dynamin 2 is required for proper lipid metabolism, mitochondria, muscle fibers, neuromuscular junctions and peripheral nerves ⬇️

scientific article published on June 27, 2013

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

scientific article

Myelination and mTOR.

scientific article

Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling

scientific article

Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin

scientific article

Neural membrane protein 35/Lifeguard is localized at postsynaptic sites and in dendrites

scientific article published in October 2002

Neuropathy in a human without the PMP22 gene.

scientific article published on June 2011

Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury

scientific article

Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.

scientific article published on 2 August 2004

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain

scientific article

Notch1 control of oligodendrocyte differentiation in the spinal cord

scientific journal article

Notch1 is required for neuronal and glial differentiation in the cerebellum.

scientific article published in January 2002

Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway.

scientific article published on 20 July 2016

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves

scientific journal article

Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease

scientific article published on January 2006

Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4

scientific article

Postnatal Schwann cell proliferation but not myelination is strictly and uniquely dependent on cyclin-dependent kinase 4 (cdk4).

scientific article

Profilin 1 is required for peripheral nervous system myelination.

scientific article published on 5 March 2014

Proliferation of Schwann cells and regulation of cyclin D1 expression in an animal model of Charcot-Marie-Tooth disease type 1A

scientific article published on 01 February 2002

Quantifying the early stages of remyelination following cuprizone-induced demyelination.

scientific article

Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system

scientific article published on 14 June 2019

Regulation of neural progenitor proliferation and survival by beta1 integrins

scientific article

SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling

scientific article

SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system

scientific article

Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.

scientific article

Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease).

scientific article published on September 2006

Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function

scientific article published on 16 January 2019

Small Rho GTPases are key regulators of peripheral nerve biology in health and disease.

scientific article published on September 2008

Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease

scientific article published on 01 November 2002

Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve

scientific article published on 12 April 2011

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.

scientific article

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

scientific article published in March 2009

Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis.

scientific article

Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells

scientific article (publication date: April 2003)

Targeting and function of the mitochondrial fission factor GDAP1 are dependent on its tail-anchor

scientific article

Temporal control of neural crest lineage generation by Wnt/β-catenin signaling

scientific article published on 9 May 2012

The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling

scientific article published on February 2011

The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

scientific article published on 29 January 2014

The Lin28/let-7 axis is critical for myelination in the peripheral nervous system

scientific article

The early life of a Schwann cell

scientific article

The function of RhoGTPases in axon ensheathment and myelination

scientific article

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells

article

The protooncogene Ski controls Schwann cell proliferation and myelination

scientific article

The raft-associated protein MAL is required for maintenance of proper axon--glia interactions in the central nervous system

scientific article

The role of the Ets domain transcription factor Erm in modulating differentiation of neural crest stem cells

scientific journal article

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.

scientific article published on March 2011

Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A).

scientific article

Understanding Schwann cell-neurone interactions: the key to Charcot-Marie-Tooth disease?

scientific article

Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord

scientific article published on 23 December 2006

Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

scientific article published on 13 June 2016

mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.

scientific article published on 9 October 2014

mTORC1 is transiently reactivated in injured nerves to promote c-Jun elevation and Schwann cell dedifferentiation.

scientific article

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