List of works - Lucie Carrier

Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice ⬇️

scientific article published on November 11, 2011

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Asymmetric septal hypertrophy in heterozygous cMyBP-C null mice

scientific article

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

scientific article

Cardiac myosin-binding protein C is required for complete relaxation in intact myocytes

scientific article (publication date: 26 October 2007)

Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction

scientific article (publication date: 24 March 2009)

Cardiomyopathy phenotypes in human-induced pluripotent stem cell-derived cardiomyocytes-a systematic review

article

Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice

scientific article

Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function

scientific article

Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure

scientific article

Defective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophy ⬇️

scientific article published on December 22, 2011

Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice

scientific article published on 15 January 2017

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

scientific article published on 03 November 2019

Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes

scientific article

Gene therapy strategies in the treatment of hypertrophic cardiomyopathy

scientific article published on 03 July 2018

How do MYBPC3 mutations cause hypertrophic cardiomyopathy? ⬇️

scientific article published on November 5, 2011

Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy

scientific article (publication date: 6 May 2003)

Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants

scientific article (publication date: April 2005)

Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice

scientific article

Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice

scientific article

Localization of Islet-1–Positive Cells in the Healthy and Infarcted Adult Murine Heart ⬇️

scientific article published on March 15, 2012

MYBPC3 in hypertrophic cardiomyopathy: from mutation identification to RNA-based correction

scientific article

Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice

scientific article

Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice

scientific article

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations

scientific article

Repair of Mybpc3 mRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy

scientific article

Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice

scientific article

Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3

scientific article published on 22 October 2019

The embryological basis of subclinical hypertrophic cardiomyopathy

scientific article

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

scientific article published on 21 December 2018

The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy

scientific article

The ubiquitin-proteasome system in cardiac dysfunction

scientific article

Ubiquitin-proteasome system and hereditary cardiomyopathies

scientific article

Ubiquitin-proteasome system impairment caused by a missense cardiac myosin-binding protein C mutation and associated with cardiac dysfunction in hypertrophic cardiomyopathy

scientific article

List of works by Lucie Carrier

Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice ⬇️

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

Asymmetric septal hypertrophy in heterozygous cMyBP-C null mice

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

Cardiac myosin-binding protein C is required for complete relaxation in intact myocytes

Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction

Cardiomyopathy phenotypes in human-induced pluripotent stem cell-derived cardiomyocytes-a systematic review

Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice

Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function

Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure

Defective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophy ⬇️

Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice

Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes

Gene therapy strategies in the treatment of hypertrophic cardiomyopathy

How do MYBPC3 mutations cause hypertrophic cardiomyopathy? ⬇️

Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy

Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants

Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice

Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice

Localization of Islet-1–Positive Cells in the Healthy and Infarcted Adult Murine Heart ⬇️

MYBPC3 in hypertrophic cardiomyopathy: from mutation identification to RNA-based correction

Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice

Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations

Repair of Mybpc3 mRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy

Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice

Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3

The embryological basis of subclinical hypertrophic cardiomyopathy

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy

The ubiquitin-proteasome system in cardiac dysfunction

Ubiquitin-proteasome system and hereditary cardiomyopathies

Ubiquitin-proteasome system impairment caused by a missense cardiac myosin-binding protein C mutation and associated with cardiac dysfunction in hypertrophic cardiomyopathy