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List of works by Bruce D. Hammock

1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells

scientific article published on 19 August 2019

<i>N</i>-Benzyl-linoleamide, a Constituent of <i>Lepidium meyenii</i> (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain

scientific article published on 15 December 2020

A clomazone immunoassay to study the environmental fate of the herbicide in rice (Oryza sativa) agriculture

journal article published in 2010

A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat

scientific article

A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents

scientific article

A label-free optical whole-cell Escherichia coli biosensor for the detection of pyrethroid insecticide exposure

scientific article published on 28 August 2019

Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model

scientific article

Aging, estrogen loss and epoxyeicosatrienoic acids (EETs)

scientific article

Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation

scientific article

Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase

scientific article

An Innovative Nanobody-Based Electrochemical Immunosensor Using Decorated Nylon Nanofibers for Point-of-Care Monitoring of Human Exposure to Pyrethroid Insecticides

scientific article published on 23 January 2020

An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application to farmers and consumers ⬇️

scientific article published on October 24, 2012

An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin

journal article published in 2006

An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan

scientific article

An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban

scientific article

An ω-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis

scientific article

Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers

scientific article

Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A

scientific article

Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine

scientific article (publication date: 2015)

Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches

scientific article

Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure

scientific article

Biomarkers of exposure to triclocarban in urine and serum ⬇️

scientific article published on May 23, 2011

Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine

scientific article

Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men ⬇️

scientific article published on May 19, 2013

Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice

journal article published in 2007

Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin

journal article published in 2015

Competitive immunochromatographic assay for the detection of the organophosphorus pesticide chlorpyrifos ⬇️

scientific article published on March 11, 2011

Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study

journal article published in 2014

Construction of Immunomagnetic Particles with High Stability in Stringent Conditions by Site-Directed Immobilization of Multivalent Nanobodies onto Bacterial Magnetic Particles for the Environmental Detection of Tetrabromobisphenol-A

scientific article published on 16 December 2019

Creatinine measurements in 24 h urine by liquid chromatography-tandem mass spectrometry

journal article published in 2008

Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor

scientific article

Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids.

scientific article published on 10 April 2017

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization

scientific article published on 21 August 2017

Delivery methods for peptide and protein toxins in insect control

journal article published in 2007

Detection of the antimicrobial triclosan in environmental samples by immunoassay

journal article published in 2016

Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand

journal article published in 2014

Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Respo

scientific article published on 19 June 2017

Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits.

scientific article

Development of a Highly Sensitive Direct Competitive Fluorescence Enzyme Immunoassay Based on a Nanobody-Alkaline Phosphatase Fusion Protein for Detection of 3-Phenoxybenzoic Acid in Urine

article

Development of a Nanobody-AviTag Fusion Protein and Its Application in a Streptavidin-Biotin-Amplified Enzyme-Linked Immunosorbent Assay for Ochratoxin A in Cereal

scientific article published on 22 August 2018

Development of a heterologous enzyme-linked immunosorbent assay for organophosphorus pesticides with phage-borne peptide

journal article published in 2014

Development of a nanobody-alkaline phosphatase fusion protein and its application in a highly sensitive direct competitive fluorescence enzyme immunoassay for detection of ochratoxin A in cereal

journal article published in 2015

Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47

journal article published in 2010

Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries

scientific article

Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment Antibodies

scientific article published on 25 September 2017

Development of an enzyme-linked immunosorbent assay for the pyrethroid cypermethrin

journal article published in 2004

Development of an immunoassay for the detection of the phenylpyrazole insecticide fipronil

journal article published in 2015

Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts

scientific article

Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies

scientific article

Development of highly sensitive fluorescent assays for fatty acid amide hydrolase

journal article published in 2007

Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products

journal article published in 2014

Development of polyclonal antibodies for the detection of styrene oxide modified proteins

journal article published in 2007

Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure

journal article published in 2007

Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos

journal article published in 2017

Discovery of Inhibitors of Soluble Epoxide Hydrolase: A Target with Multiple Potential Therapeutic Indications ⬇️

scientific article published on January 17, 2012

Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products

scientific article published on 28 December 2020

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

scientific article published on 17 September 2019

Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis

journal article published in 2014

Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation

scientific article

Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay ⬇️

scientific article published on September 6, 2012

Enhanced sensitive immunoassay: noncompetitive phage anti-immune complex assay for the determination of malachite green and leucomalachite green

scientific article

Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles

scientific article (publication date: 2005)

Epoxide hydrolases: their roles and interactions with lipid metabolism

scientific article (publication date: 2005)

Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling.

scientific article published on 6 November 2017

Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response

scientific article

Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation

scientific article published on 2 January 2018

Evaluation of the Immune Response of Patulin by Proteomics

scientific article published in 2024

Fluorescent "Turn off-on" Small-Molecule-Monitoring Nanoplatform Based on Dendrimer-like Peptides as Competitors

scientific article published on 30 August 2019

Hapten Synthesis, Antibody Development, and a Highly Sensitive Indirect Competitive Chemiluminescent Enzyme Immunoassay for Detection of Dicamba

scientific article published on 07 May 2019

Hapten and antibody production for a sensitive immunoassay determining a human urinary metabolite of the pyrethroid insecticide permethrin

journal article published in 2004

Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase

scientific article

Highly Specific Monoclonal Antibody and Sensitive Quantum Dot Beads-Based Fluorescence Immunochromatographic Test Strip for Tebuconazole Assay in Agricultural Products

scientific article published on 05 August 2019

Hydroxy-fipronil is a new urinary biomarker of exposure to fipronil

journal article published in 2017

Immunoassays and Biosensors for Monitoring Environmental and Human Exposure to Pyrethroid Insecticides ⬇️

scientific article published on November 24, 2010

Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides ⬇️

scientific article published on June 30, 2011

Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health

scientific article

Importance of membrane selection in the development of immunochromatographic assays for low-molecular weight compounds

scientific article

In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens

journal article published in 2008

Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase

scientific article published on 30 January 2020

Indirect Homologous Competitive Enzyme-Linked Immunosorbent Assay for the Detection of a Class of Glycosylated Dihydrochalcones ⬇️

scientific article published on July 2, 2013

Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain–gut–microbiota axis via the subdiaphragmatic vagus nerve

scientific article published on 11 June 2021

Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice ⬇️

scientific article published on June 14, 2012

Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK

scientific article published on 25 February 2019

Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice

scientific article

Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides

scientific article

Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model

scientific article

Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation

scientific article

Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats

scientific article published on 15 March 2017

Investigation of human exposure to triclocarban after showering and preliminary evaluation of its biological effects

journal article published in 2011

Investigation of the Small Size of Nanobodies for a Sensitive Fluorescence Polarization Immunoassay for Small Molecules: 3-Phenoxybenzoic Acid, an Exposure Biomarker of Pyrethroid Insecticides as a Model

scientific article published on 07 October 2019

Isolation of Alpaca Anti-Hapten Heavy Chain Single Domain Antibodies for Development of Sensitive Immunoassay ⬇️

scientific article published on December 29, 2011

Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay

journal article published in 2013

Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation

scientific article published on 19 March 2019

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission

scientific article

Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase

scientific article

Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation

scientific article published in May 2018

Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides

journal article published in 2009

Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase

scientific article published on 12 May 2020

Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts

scientific article

Metabolism of the antibacterial triclocarban by human epidermal keratinocytes to yield protein adducts

journal article published in 2012

Metabolomics--a new exciting field within the "omics" sciences

scientific article

Method for sorting and pairwise selection of nanobodies for the development of highly sensitive sandwich immunoassays

journal article published in 2015

Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents

scientific article

Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men

scientific article

Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid

journal article published in 2012

Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol

scientific article published in 2013

Multiplexed immunoassays for proteins using magnetic luminescent nanoparticles for internal calibration

journal article published in 2007

Nanobody Based Immunoassay for Human Soluble Epoxide Hydrolase Detection Using Polymeric Horseradish Peroxidase (PolyHRP) for Signal Enhancement: The Rediscovery of PolyHRP?

scientific article published on 10 May 2017

Nanopeptamers for the Development of Small-Analyte Lateral Flow Tests with a Positive Readout ⬇️

scientific article published on December 20, 2012

Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling

scientific article published on 01 May 2018

Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules

journal article published in 2011

Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor

journal article published in 2022

Novel and highly sensitive fluorescent assay for leucine aminopeptidases

scientific article

Nutritional lipidomics: molecular metabolism, analytics, and diagnostics

scientific article

Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales

scientific article

Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice

scientific article published on 2 October 2017

Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model

scientific article

One scorpion, two venoms: prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action

scientific article

One-Step Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Fusion for Detection of Aflatoxin B1 in Cereal

scientific article published on 24 April 2019

Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis

scientific article

Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase

scientific article

Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy

scientific article

Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern

scientific article

Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain

scientific article published on 3 April 2018

Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation

scientific article

Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive

scientific article

Phage-Displayed Peptide That Mimics Aflatoxins and Its Application in Immunoassay ⬇️

scientific article published on February 27, 2013

Phage-Mediated Competitive Chemiluminescent Immunoassay for Detecting Cry1Ab Toxin by Using an Anti-Idiotypic Camel Nanobody.

scientific article published on 2 January 2018

Phage-borne peptidomimetics accelerate the development of polyclonal antibody-based heterologous immunoassays for the detection of pesticide metabolites

journal article published in 2007

Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation

scientific article

Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs

scientific article

Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats

scientific article

Photonic Crystal Lab-On-a-Chip for Detecting Staphylococcal Enterotoxin B at Low Attomolar Concentration ⬇️

scientific article published on March 7, 2013

Possible role of Epoxyeicosatrienoic acid in prevention of oxidative stress mediated neuroinflammation in Parkinson disorders

scientific article

Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo

scientific article

Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice

scientific article published on 20 June 2019

Pyrethroids in house dust from the homes of farm worker families in the MICASA study

journal article published in 2013

Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays

scientific article published on 21 December 2018

Quantitative profiling method for oxylipin metabolome by liquid chromatography electrospray ionization tandem mass spectrometry

scientific article

Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa

scientific article

Recruiting strategy and 24-hour biomonitoring of paraquat in agricultural workers

scientific article

Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation

scientific article

Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid

scientific article

Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression

scientific article published on 14 August 2020

Sensitive Immunoassay for Detection and Quantification of the Neurotoxin, Tetramethylenedisulfotetramine

scientific article

Smartphone-based dual-channel immunochromatographic test strip with polymer quantum dot labels for simultaneous detection of cypermethrin and 3-phenoxybenzoic acid

journal article published in 2021

Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay

scientific article

Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases

scientific article

Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance ⬇️

scientific article published on May 12, 2011

Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice

scientific article

Soluble epoxide hydrolase expression in a porcine model of arteriovenous graft stenosis and anti-inflammatory effects of a soluble epoxide hydrolase inhibitor

scientific article

Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension

scientific article

Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia.

scientific article

Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception

scientific article

Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model

scientific article published on 13 May 2020

Soluble epoxide hydrolase inhibitors and heart failure

scientific article

Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation

scientific article published on 27 March 2020

Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease

scientific article published on 07 May 2018

Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy

scientific article

Soluble epoxide hydrolase-dependent regulation of myogenic response and blood pressure

scientific article

Soluble epoxide hydrolase: Gene structure, expression and deletion ⬇️

scientific article published on May 20, 2013

Soluble epoxide hydrolase: a novel therapeutic target in stroke

scientific article

Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer

scientific article

Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis

scientific article

Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor

scientific article published on 15 January 2019

Synthesis and structure–activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors

scientific article

The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain

scientific article

The Western Center for Agricultural Health and Safety

final cooperative agreement report published in 2017

The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor

scientific article

The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways

scientific article

The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling

scientific article

The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity

scientific article

Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors

journal article published in 2009

Triclocarban enhances testosterone action: a new type of endocrine disruptor?

scientific article

Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle

scientific article

Using a quantum dot bead-based lateral flow immunoassay to broadly detect the adulteration of PDE-5 inhibitors in functional foods

scientific article published in 2022

VHH antibodies: emerging reagents for the analysis of environmental chemicals

journal article published in 2016

VHH phage-based competitive real-time immuno-polymerase chain reaction for ultrasensitive detection of ochratoxin A in cereal

journal article published in 2014

Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels ⬇️

scientific article published on January 23, 2012

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