List of works - Caroline Hayward

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Complement C3 variant and the risk of age-related macular degeneration

scientific article

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

New loci associated with kidney function and chronic kidney disease

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

scientific journal article

Runs of homozygosity in European populations

scientific article

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association study identifies five loci associated with lung function

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

scientific article published on 21 December 2015

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Mutations in SOX2 cause anophthalmia

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

A general approach for haplotype phasing across the full spectrum of relatedness

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

scientific article published on 26 February 2018

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

article

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

scientific article

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

scientific article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Cognitive change and the APOE epsilon 4 allele

scientific article (publication date: 29 August 2002)

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

scientific article published on 06 January 2013

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

List of works by Caroline Hayward

Biological, clinical and population relevance of 95 loci for blood lipids

Genetic studies of body mass index yield new insights for obesity biology

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Discovery and refinement of loci associated with lipid levels

Defining the role of common variation in the genomic and biological architecture of adult human height

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

New genetic loci link adipose and insulin biology to body fat distribution

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Complement C3 variant and the risk of age-related macular degeneration

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

New loci associated with kidney function and chronic kidney disease

Genome-wide association study identifies 74 loci associated with educational attainment

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

Runs of homozygosity in European populations

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Genome-wide association study identifies five loci associated with lung function

Common variants associated with plasma triglycerides and risk for coronary artery disease

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Mutations in SOX2 cause anophthalmia

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

A general approach for haplotype phasing across the full spectrum of relatedness

FTO genotype is associated with phenotypic variability of body mass index

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Rare and low-frequency coding variants alter human adult height

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

Cognitive change and the APOE epsilon 4 allele

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders