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List of works by Sudha Seshadri

19th Workshop of the International Stroke Genetics Consortium, April 28-29, 2016, Boston, Massachusetts, USA: 2016.001 MRI-defined cerebrovascular genomics-The CHARGE consortium

scientific article published on 30 March 2017

50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study

scientific article

A GENOME-WIDE META-ANALYSIS OF PLASMA CLUSTERIN LEVELS IN THE CHARGE CONSORTIUM

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

scientific article published on 19 June 2017

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

scientific article published on 02 August 2019

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

scientific article published on 14 January 2019

A genome-wide association study of aging

scientific article

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

scientific article

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

A priori collaboration in population imaging: The Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement consortium

scientific article published on 31 October 2015

A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: the VEGF Consortium

scientific article published on 01 March 2018

APOE and mild cognitive impairment: the Framingham Heart Study

scientific article

APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality

scientific article published on 01 December 2018

APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis

scientific article

APOE genotype modifies the relationship between midlife vascular risk factors and later cognitive decline

scientific article published on 17 April 2013

APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.

scientific article

ATP5H/KCTD2 locus is associated with Alzheimer's disease risk.

scientific article

Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study

scientific article published on 15 October 2019

Adipokines are associated with MRI markers of brain aging in young adults

Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits.

scientific article published on 17 October 2017

Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.

scientific article published on 09 April 2013

Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype

scientific article published on 10 June 2019

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Antecedent blood pressure and risk of cardiovascular disease: the Framingham Heart Study .

scientific article published on January 2002

Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies

scientific article published on 06 November 2019

Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia

scientific article published on 4 August 2016

Apolipoprotein E epsilon 4 allele and the lifetime risk of Alzheimer's disease. What physicians know, and what they should know

scientific article published in November 1995

Apolipoprotein epsilon 4 allele modifies waist-to-hip ratio effects on cognition and brain structure

scientific article published on 10 August 2011

Are Trends in Dementia Incidence Associated With Compression in Morbidity? Evidence From The Framingham Heart Study

scientific article published on 01 April 2018

Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes

scientific article published on 01 May 2019

Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan.

scientific article published on 3 January 2012

Association between neuropathology and brain volume in the Framingham Heart Study.

scientific article

Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study

scholarly article published 5 April 2019

Association of Alzheimer's disease GWAS loci with MRI markers of brain aging

scientific article

Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study

scientific article published on 11 January 2016

Association of CD14 with incident dementia and markers of brain aging and injury

scientific article published on 09 December 2019

Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study ⬇️

scientific article published on 22 December 2015

Association of HSP70 and its co-chaperones with Alzheimer's disease

scientific article

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia

scientific article published on 12 April 2016

Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study

scientific article

Association of Nonalcoholic Fatty Liver Disease With Lower Brain Volume in Healthy Middle-Aged Adults in the Framingham Study.

scientific article published on 20 November 2017

Association of Physical Function with Clinical and Subclinical Brain Disease: The Framingham Offspring Study

scientific article published on July 2016

Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study

scientific article published on 06 February 2016

Association of alcohol consumption with brain volume in the Framingham study

scientific article

Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study

scientific article published on 08 June 2017

Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia

scientific article published on 03 January 2020

Association of arterial stiffness with progression of subclinical brain and cognitive disease

scientific article published on 20 January 2016

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

scientific article published on 28 February 2018

Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: the Framingham Offspring Study

scientific article

Association of common genetic variants with brain microbleeds: A Genome-wide Association Study

scientific article published on 10 September 2020

Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study

scientific article

Association of matrix metalloproteinases with MRI indices of brain ischemia and aging

scientific article

Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study

scientific article

Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts

scholarly article by Galit Weinstein et al published 2019 in PLOS ONE

Association of parental dementia with cognitive and brain MRI measures in middle-aged adults

scientific article published on 09 December 2009

Association of parental stroke with brain injury and cognitive measures in offspring: the Framingham Heart Study

scientific article published on 29 January 2013

Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study

scientific article published on 30 July 2009

Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging

scientific article

Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study

scientific article

Association of the endogenous nitric oxide synthase inhibitor ADMA with carotid artery intimal media thickness in the Framingham Heart Study offspring cohort

scientific article published on 04 June 2009

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study

scientific article published on February 2006

Associations between social relationship measures, serum brain-derived neurotrophic factor, and risk of stroke and dementia

scientific article published on 22 March 2017

Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke

scientific article

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium

scientific article

Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk.

scientific article published on 7 November 2017

Asymptomatic eosinophilic myocarditis: 2 + 2 = 4 or 5!

scientific article published on 01 June 1991

Atrial fibrillation is associated with lower cognitive performance in the Framingham offspring men.

scientific article published in September 2006

Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study).

scientific article published on 30 April 2016

Atrial flutter: Clinical risk factors and adverse outcomes in the Framingham Heart Study

scientific article

Atrial natriuretic peptide: an atavistic hormone?

scientific article published on 01 March 1989

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Author response: Blood pressure from mid- to late life and risk of incident dementia

scientific article published on 01 July 2018

Author response: Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study

scientific article published on 01 October 2019

Author response: Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham study

scientific article published on 18 December 2019

Author response: Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia

scientific article

Beauty and the beast: B12, homocysteine, and the brain: a bemusing saga!

scientific article published on October 2010

Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study

scientific article

Bivariate heritability of total and regional brain volumes: the Framingham Study

scientific article published on July 2009

Blood pressure from mid- to late life and risk of incident dementia

scientific article published on 8 November 2017

Bone mineral density and the risk of Alzheimer disease

scientific article published in January 2005

Bone mineral density and verbal memory impairment: Third National Health and Nutrition Examination Survey

scientific article

Botulinum toxin A in blepharospasm and hemifacial spasm

scientific article published on 01 March 1994

Brain imaging and cognitive predictors of stroke and Alzheimer disease in the Framingham Heart Study

scientific article published on 06 August 2013

COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls

scientific article published on 27 September 2017

COSMIC (Cohort Studies of Memory in an International Consortium): an international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups

scientific article

Cardiac index is associated with brain aging: the Framingham Heart Study

scientific article

Cardiovascular risk profile in women and dementia

scientific article

Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study

scientific article

Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study

scientific article

Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study.

scientific article

Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study.

scientific article

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition

scientific article published on 09 August 2018

Circulating IGFBP-2: a novel biomarker for incident dementia

scientific article published on 02 August 2019

Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals

scientific article published on 03 September 2019

Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults

Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study

scientific article published on 24 August 2016

Circulating biomarkers that predict incident dementia

scientific article

Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community

scientific article

Circulating ceramide ratios and risk of vascular brain aging and dementia

scientific article published on 16 January 2020

Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study

scientific article published on 24 October 2018

Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study

scientific article published on 04 March 2019

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

scientific article

Circulating vascular endothelial growth factor and the risk of cardiovascular events

scientific article published on 27 June 2016

Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1).

scientific article published in January 2018

Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study.

scientific article published on 19 August 2015

Cognitive performance after stroke--the Framingham Heart Study

scientific article

Common genetic variants influence human subcortical brain structures

scientific article

Common polygenic variation enhances risk prediction for Alzheimer's disease

scientific article published on 21 October 2015

Common variants at 12q14 and 12q24 are associated with hippocampal volume

scientific article

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

Common variants at 6q22 and 17q21 are associated with intracranial volume

scientific article published on 15 April 2012

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

scientific article

Computing estimates of incidence, including lifetime risk: Alzheimer's disease in the Framingham Study. The Practical Incidence Estimators (PIE) macro.

scientific article published on June 2000

Constructional Apraxia Reversed With Methylprednisolone

scientific article published on 01 January 2012

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

article published in 2018

Defining MCI in the Framingham Heart Study Offspring: education versus WRAT-based norms

scientific article published on October 2013

Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association

scientific article published on 7 September 2017

Delaying dementia: can antihypertensives prevent Alzheimer dementia?

scientific article published on 2 August 2013

Dementia after stroke: the Framingham Study

scientific article published on 29 April 2004

Depressive symptoms and risk of dementia: the Framingham Heart Study

scientific article

Development and validation of a brief dementia screening indicator for primary care

scientific article

Diabetes and stroke

Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study

scientific article published in November 2006

Diabetes-Related Topics in an Online Forum for Caregivers of Individuals Living With Alzheimer Disease and Related Dementias: Qualitative Inquiry

scientific article published on 06 July 2020

Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage

scientific article

Dipping to clear amyloid: Cerebrovascular reactivity and neurodegeneration--cause or effect?

scientific article published on 4 November 2015

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis

scientific article published on 01 February 2019

Dynamic measurements of β-amyloid accumulation: The early effect of APOE.

scientific article published on 9 August 2017

Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study

scientific article published on 10 March 2016

Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study

scientific article

Elevated midlife blood pressure increases stroke risk in elderly persons: the Framingham Study

scientific article published on October 2001

Elevated plasma homocysteine levels: risk factor or risk marker for the development of dementia and Alzheimer's disease?

scientific article published on August 2006

Erratum: Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function and bipolar disorder susceptibility

scholarly article published in Molecular Psychiatry

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

scholarly article published in Nature Genetics

Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume

article

Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease

scientific article published on 18 June 2016

Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases

scientific article

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Factors Associated With New-Onset Depression After Stroke

scientific article

Fitness and cognition in the elderly: The Austrian Stroke Prevention Study

scientific article published on 6 January 2016

Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene

scientific article

Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes

scientific article

Framingham stroke risk profile and lowered cognitive performance

scientific article published on 15 January 2004

Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings

scientific article published on 30 March 2019

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

scientific article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

scientific article

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

scientific article

Gender and incidence of dementia in the Framingham Heart Study from mid-adult life

scientific article

Gender differences in stroke incidence and poststroke disability in the Framingham heart study

scientific article published on 10 February 2009

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

scientific article published on 08 July 2019

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genes from a translational analysis support a multifactorial nature of white matter hyperintensities

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

article published in 2018

Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke

scientific article

Genetic Interaction with Plasma Lipids on Alzheimer's Disease in the Framingham Heart Study

scientific article published on 01 January 2018

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.

scientific article published on 27 February 2018

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

scientific article

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study

scientific article

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study

scientific article

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

scientific article published on 22 September 2020

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus

scientific article

Genetic overlap between diagnostic subtypes of ischemic stroke

scientific article

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

scientific article published on 5 October 2012

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variation at 16q24.2 is associated with small vessel stroke

scientific article

Genetics of Alzheimer’s Disease

article

Genetics of atherothrombotic and lacunar stroke

scientific article

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

scientific article published in PLoS ONE

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2

scientific article

Genome-wide Association Study Links APOEϵ4 and BACE1 Variants with Plasma Amyloid β Levels

Genome-wide analysis of genetic loci associated with Alzheimer disease

scientific article

Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment

scientific article published on 23 October 2019

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

scientific article

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium

scientific article

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

scientific article published in Nature Communications

Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine

scientific article published on 21 September 2014

Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke

scientific article

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

scientific article

Genomewide association studies of stroke

scientific article published on 15 April 2009

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Glucose indices are associated with cognitive and structural brain measures in young adults

scientific article published on 6 May 2015

Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

scientific article published on 26 February 2019

Heart of the Matter

scientific article

Hepatic steatosis and cardiovascular disease outcomes: An analysis of the Framingham Heart Study

scientific article published on 14 March 2015

Homocysteine and cognitive performance in the Framingham offspring study: age is important

scientific article published on 17 August 2005

Homocysteine and the Risk of Dementia ⬇️

scientific article published on April 17, 2012

Homocysteine and the brain: vascular risk factor or neurotoxin?

scientific article published in January 2003

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels

scientific article

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Immunohistochemical Analysis of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) Expression in the Rat and Human Hippocampus: Decline in CA3 During Progression of Alzheimer's Disease.

scientific article

Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association

scientific article published on 10 October 2016

Incidence of Dementia over Three Decades in the Framingham Heart Study

scientific article published on February 2016

Incidence of seizures following initial ischemic stroke in a community-based cohort: The Framingham Heart Study

scientific article published on 18 March 2017

Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology

scientific article

Indexes of subclinical atherosclerosis: signposts on the highway to disease

scientific article published on 10 November 2014

Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander?

scientific article

Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study

scientific article published on March 2007

Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study

scientific article

Inflammatory markers and neuropsychological functioning: the Framingham Heart Study

scientific article

Inflammatory markers and the risk of Alzheimer disease: the Framingham Study

scientific article published on May 2007

Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

scientific article

Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults

scientific article published on 17 August 2017

Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology

scientific article

Interactive effects of apolipoprotein E type 4 genotype and cerebrovascular risk on neuropsychological performance and structural brain changes

scientific article

Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury

scientific article

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

scientific article published on 13 July 2019

Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study

scientific article published on 12 March 2012

Ischemic stroke is associated with the ABO locus: the EuroCLOT study

scientific article published on January 2013

Job Strain and Cognitive Decline: A Prospective Study of the Framingham Offspring Cohort

scientific article (publication date: April 2015)

Lacunar Infarcts and Intracerebral Hemorrhage Differences: A Nested Case-Control Analysis in the FHS (Framingham Heart Study).

scientific article published on 22 December 2016

Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project

scientific article published on 16 August 2011

Left ventricular hypertrophy in association with cognitive impairment: a systematic review and meta-analysis

scientific article published on 16 February 2017

Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring

scientific article published on 15 January 2007

Lexical retrieval in discourse: an early indicator of Alzheimer's dementia

scientific article

Lifelong Reading Disorder and Mild Cognitive Impairment: Implications for Diagnosis

scientific article published on 25 November 2015

Lifetime risk of dementia and Alzheimer's disease. The impact of mortality on risk estimates in the Framingham Study

scientific article published in December 1997

Lifetime risk of stroke and dementia: current concepts, and estimates from the Framingham Study

scientific article published on December 2007

Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study

scientific article

Lipoprotein phospholipase A2 and cerebral microbleeds in the Framingham Heart Study

scientific article

Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure

scientific article published on May 2015

Low cardiac index is associated with incident dementia and Alzheimer disease: the Framingham Heart Study

scientific article

Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration.

scientific article

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

scientific article

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

Meta-analysis of epigenome-wide association studies of cognitive abilities

scientific article published on 8 January 2018

Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.

scientific article published on 29 July 2017

Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts

scholarly article by Sarah C Conner et al published 2019 in Journal of Alzheimer's Disease

Methodology for measuring cerebrovascular disease burden

scientific article

Mid-life Cardiovascular Risk Impacts Memory Function: The Framingham Offspring Study.

scientific article

Mid-life and late-life vascular risk factor burden and neuropathology in old age

scientific article published on 05 November 2019

Midlife Hypertension Risk and Cognition in the Non-Demented Oldest Old: Framingham Heart Study

scientific article published on July 2015

Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later

scientific article published on 10 February 2016

Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline.

scientific article

Modulators of cytoskeletal reorganization in CA1 hippocampal neurons show increased expression in patients at mid-stage Alzheimer's disease

scientific article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

scientific article published on 7 February 2015

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

scientific article

Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study

scientific article

Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease

scientific article

Neck Circumference, Brain Imaging Measures, and Neuropsychological Testing Measures

scientific article published on 4 April 2016

Neck circumference, carotid wall intima-media thickness, and incident stroke

scientific article published on September 2013

Neurological manifestations of AIDS.

scientific article published on April 1994

Neuropsychological Criteria for Mild Cognitive Impairment and Dementia Risk in the Framingham Heart Study

scientific article published on 31 March 2016

New Norms for a New Generation: Cognitive Performance in the Framingham Offspring Cohort

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

No association of ALOX5AP polymorphisms with risk of MRI-defined brain infarcts.

scientific article published on 9 November 2011

Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study

scientific article published on 26 June 2019

Normative Data for the Cognitively Intact Oldest-Old: The Framingham Heart Study.

scientific article

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Nucleic acid amplification tests for tuberculous meningitis: a systematic review of diagnostic accuracy.

scientific article published on September 2003

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association

scientific article published on 01 March 2019

Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2.

scientific article

Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study

scientific article published on 24 June 2017

PLD3 variants in population studies

scientific article published on April 2015

Parental longevity is associated with cognition and brain ageing in middle-aged offspring

scientific article

Parental occurrence of stroke and risk of stroke in their children: the Framingham study

scientific article

Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study

scientific article published on 15 July 2016

Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis

scientific article published on 17 April 2019

Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study

scientific article

Plasma clusterin levels and risk of dementia, Alzheimer's disease, and stroke

scientific article published on 09 July 2016

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

scientific article

Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study

scientific article published in May 2003

Plasma total-tau as a biomarker of stroke risk in the community

scientific article published on 29 July 2019

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

scientific article

Polygenic risk of ischemic stroke is associated with cognitive ability

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Population Neuroscience: Dementia Epidemiology Serving Precision Medicine and Population Health

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Population Normative Data for the CERAD Word List and Victoria Stroop Test in Younger- and Middle-Aged Adults: Cross-Sectional Analyses from the Framingham Heart Study

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Postmenopausal Estrogen Replacement Therapy and the Risk of Alzheimer Disease

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Predicting stroke through genetic risk functions: the CHARGE Risk Score Project

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Prevalence and correlates of silent cerebral infarcts in the Framingham offspring study

scientific article published on 26 June 2008

Prevention of Dementia-Thinking Beyond the Age and Amyloid Boxes

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Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

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Profiles by sex of brain MRI and cognitive function in the framingham offspring study

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Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia.

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Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

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Pulse Pressure Is Associated With Early Brain Atrophy and Cognitive Decline: Modifying Effects of APOE-ε4.

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Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project

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Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

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Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project

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Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging. ⬇️

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Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study)

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Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study

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Relations of arterial stiffness and endothelial function to brain aging in the community

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Reply Effect yes, role no!

Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease

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Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study

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Response by Aparicio et al to Letter Regarding Article, "Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study"

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Response by Lubitz et al to Letter Regarding Article, "Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study".

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Response by Pase et al to Letter Regarding Article, "Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study".

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Response by Pase et al to Letter Regarding Article, "Sweetened Beverages and the Risks of Incident Stroke and Dementia".

scientific article published on 7 August 2017

Response by Pase et al to Letters Regarding Article, "Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia. A Prospective Cohort Study".

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Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

scientific article published on 01 July 2018

Revised Framingham Stroke Risk Profile to Reflect Temporal Trends

scientific article published on 3 February 2017

Risk estimations, risk factors, and genetic variants associated with Alzheimer's disease in selected publications from the Framingham Heart Study

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Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study

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Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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Serum Leptin Levels and the Risk of Stroke: The Framingham Study

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Serum brain-derived neurotrophic factor and risk of atrial fibrillation.

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Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study

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Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study

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Serum brain-derived neurotrophic factor as a predictor of incident dementia-reply.

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Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.

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Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke

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Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

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Silent Brain Infarction and Risk of Future Stroke: A Systematic Review and Meta-Analysis.

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Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies

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Sleep architecture and the risk of incident dementia in the community

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Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging

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Statins and the risk of dementia

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Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study

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Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study

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Stroke risk profile, brain volume, and cognitive function: The Framingham Offspring Study

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Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities

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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

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Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology.

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Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study

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The Alzheimer's Disease Sequencing Project: Study design and sample selection

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The Framingham Brain Donation Program: neuropathology along the cognitive continuum

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The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports

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The Framingham Heart Study clock drawing performance: normative data from the offspring cohort

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The changing prevalence and incidence of dementia over time - current evidence.

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The genetic architecture of the human cerebral cortex

The genetic architecture of the human cerebral cortex

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The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

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The lifetime risk of stroke: estimates from the Framingham Study

scientific article published on 5 January 2006

The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort

scientific article published on 9 November 2011

Thyroid function and the risk of Alzheimer disease: the Framingham Study

scientific article published on July 2008

Top research priorities for stroke genetics

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Transient global amnesia and neurological events: the framingham heart study

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Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 years

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Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium

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Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia

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Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study

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Understanding brain function through small vessel disease: what zebras can teach us about horses

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Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

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Understanding the link between obesity and dementia in older adults

scholarly article by Sudha Seshadri published December 2010 in Aging Health

Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study

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Validation of secondary data sources to identify Parkinson disease against clinical diagnostic criteria

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Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association

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Vascular dysfunction-The disregarded partner of Alzheimer's disease

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Vascular risk at younger ages most strongly associates with current and future brain volume

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Vascular risk factor burden and new-onset depression in the community

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Vascular risk factors and dementia revisited

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Verbal memory and brain aging: an exploratory analysis of the role of error responses in the Framingham Study

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Visceral fat is associated with lower brain volume in healthy middle-aged adults

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Visual association pathology in preclinical Alzheimer disease

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Vitamin D concentration and lateral cerebral ventricle volume in older adults

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Walking Speed, Handgrip Strength and Risk of Dementia and Stroke: The Framingham Offspring Study (S24.003)

scholarly article by E. Camargo et al published 22 April 2012 in Neurology

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality:

White Matter Lesion Progression: Genome-Wide Search for Genetic Influences

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White matter hyperintensity and cognitive functioning in the racial and ethnic minority cohort of the Framingham Heart Study

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Whole blood gene expression and white matter Hyperintensities.

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Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study

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Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study

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Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.

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Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

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Whole genome sequence analyses of brain imaging measures in the Framingham Study

scientific article published on 27 December 2017

δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes

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