List of works by Bernard Le Foll

A 35-year-old woman with low mood and concerns about her alcohol use.

scientific article published in February 2017

A Preliminary Investigation of the Effect of Acute Alcohol on Dopamine Transmission as Assessed by [11 C]-(+)-PHNO.

scientific article

A case of diagnosing a long-standing psychotic disorder during medical withdrawal

scientific article published on 27 March 2012

A review of positron emission tomography studies exploring the dopaminergic system in substance use with a focus on tobacco as a co-variate

scientific article published on 30 November 2016

A selective role for dopamine D₄ receptors in modulating reward expectancy in a rodent slot machine task

scientific article published on 4 October 2013

A single cocaine exposure increases BDNF and D3 receptor expression: implications for drug-conditioning.

scientific article published in February 2005

A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study

scientific article published on 05 October 2018

Admixture analysis of age at onset in schizophrenia: genetic association study of 45 candidate loci

scientific article published on 20 December 2011

Alcohol Intoxication by Binge Drinking Impairs Neuroplasticity

scientific article published on 28 August 2015

Alcohol inhalation

scientific article

Analysis of CpG SNPs in 34 genes: association test with suicide attempt in schizophrenia.

scientific article published on 14 May 2013

Analysis of treatment-resistant schizophrenia and 384 markers from candidate genes

scientific article

Association of a polymorphism in the NRXN3 gene with the degree of smoking in schizophrenia: a preliminary study

scientific article published in January 2009

Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia

scientific article published on 25 April 2010

Association of the orphan nuclear receptor NR4A1 with tardive dyskinesia

scientific article

Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs.

scientific article published on 24 July 2010

Attenuation of cue-induced reinstatement of nicotine seeking by URB597 through cannabinoid CB1 receptor in rats

scientific article published on 11 February 2016

Baseline expression of alpha4beta2* nicotinic acetylcholine receptors predicts motivation to self-administer nicotine

scientific article published on 18 December 2008

Bipolar disorder and co-occurring cannabis use disorders: characteristics, co-morbidities and clinical correlates.

scientific article published on 10 January 2013

Blockade of dopamine d4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in rats

scientific article published on 26 October 2011

Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors

scientific journal article

Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies

scientific article published on June 2008

Brain Stimulation in Alcohol Use Disorders: Investigational and Therapeutic Tools

scientific article published on 14 October 2015

Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway

scientific article published on January 2004

Cannabinoid CB1 receptor antagonists as promising new medications for drug dependence.

scientific article

Cannabinoids: Friend or foe?

scientific article published on June 2015

Cannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?

scientific article published on 11 February 2013

Cannabis use and cannabis use disorders among individuals with mental illness.

scientific article

Cannabis use and mental health-related quality of life among individuals with anxiety disorders

scientific article published on 20 July 2012

Child marriage in the United States and its association with mental health in women

scientific article published on 28 August 2011

Circadian alteration in neurobiology during protracted opiate withdrawal in rats.

scientific article published on 25 August 2010

Clonidine attenuates morphine withdrawal and subsequent drug sensitization in rhesus monkeys

scientific article published in April 2007

Combining alcohol interventions with tobacco addictions treatment in primary care-the COMBAT study: a pragmatic cluster randomized trial

scientific article published on 18 May 2017

Conditioned place preference induced by licit drugs: establishment, extinction, and reinstatement.

scientific article published on 14 December 2008

Corticotropin-releasing hormone and dopamine release in healthy individuals

scientific article published in December 2016

Development and Implementation of an Ambulatory Integrated Care Pathway for Major Depressive Disorder and Alcohol Dependence

scientific article published on 17 August 2015

Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys.

scientific article

Dopamine D3 receptor agents as potential new medications for drug addiction

scientific article published in March 2000

Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone

scientific article

Dopamine D3 receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam.

scientific article published on 8 June 2010

Dopamine D3 receptors in the basolateral amygdala and the lateral habenula modulate cue-induced reinstatement of nicotine seeking.

scientific article

Dopamine D4 receptors in psychostimulant addiction

scientific article

Effect of a D3 receptor antagonist on context-induced reinstatement of nicotine seeking

scientific article published on 13 August 2015

Effects of a selective cannabinoid CB2 agonist and antagonist on intravenous nicotine self administration and reinstatement of nicotine seeking

scientific article

Effects of chronic caffeine exposure on adenosinergic modulation of the discriminative-stimulus effects of nicotine, methamphetamine, and cocaine in rats

scientific article published on 08 August 2008

Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels.

scientific article published on 30 October 2017

Effects of fixed or self-titrated dosages of Sativex on cannabis withdrawal and cravings.

scientific article published on 23 February 2016

Effects of nicotine in experimental animals and humans: an update on addictive properties

scientific article published on January 2009

Effects of varenicline on motor cortical plasticity in non-smokers with schizophrenia.

scientific article published on 6 September 2016

Effects of various cannabinoid ligands on choice behaviour in a rat model of gambling

scientific article published on 22 February 2016

Elevation of dopamine induced by cigarette smoking: novel insights from a [11C]-+-PHNO PET study in humans

scientific article published on 19 August 2013

Evaluating the Impact of Naltrexone on the Rat Gambling Task to Test Its Predictive Validity for Gambling Disorder

scientific article

Exposure to nicotine produces an increase in dopamine D2(High) receptors: a possible mechanism for dopamine hypersensitivity

scientific article published on November 2010

Fatty Acid Amide Hydrolase Binding in Brain of Cannabis Users: Imaging With the Novel Radiotracer [11C]CURB.

scientific article

Gender differences in health-related quality of life among cannabis users: results from the National Epidemiologic Survey on Alcohol and Related Conditions

scientific article

Genetics of dopamine receptors and drug addiction: a comprehensive review

scientific article published on February 2009

Granular insular cortex inactivation as a novel therapeutic strategy for nicotine addiction.

scientific article published on 17 March 2010

High reinforcing efficacy of nicotine in non-human primates

scientific article

Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum

scientific article

Impact of age at onset of cannabis use on cannabis dependence and driving under the influence in the United States.

scientific article published on 24 December 2014

Impact of hypertension and body mass index on quality of life in schizophrenia

scientific article published in May 2011

Impact of short access nicotine self-administration on expression of α4β2* nicotinic acetylcholine receptors in non-human primates

scientific article published on 25 February 2016

Improvement of the association between self-reported pill count and varenicline levels following exclusion of participants with misreported pill count: A commentary on Peng et al. (2017).

scientific article published on 2 December 2017

Increased dopamine D3 receptor expression accompanying behavioral sensitization to nicotine in rats.

scientific article

Influence of neurexin 1 (NRXN1) polymorphisms in clozapine response.

scientific article published on 22 September 2010

Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats

scientific article published on 25 August 2008

Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice.

scientific article

Integrated care pathway for co-occurring major depressive and alcohol use disorders: Outcomes of the first two years.

scientific article published on June 2017

Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders

scientific article

Involvement of the caudal granular insular cortex in alcohol self-administration in rats.

scientific article

Involvement of the rostral agranular insular cortex in nicotine self-administration in rats

scientific article

List of Contributors

Lower-Risk Cannabis Use Guidelines: A Comprehensive Update of Evidence and Recommendations.

scientific article published in August 2017

Lower-Risk Cannabis Use Guidelines: A Comprehensive Update of Evidence and Recommendations.

scientific article published on 23 June 2017

Major depression and suicide attempts in patients with liver disease in the United States.

scientific article published on 23 June 2014

Management of mood and anxiety disorders in patients receiving opioid agonist therapy: Review and meta-analysis

scientific article

Multiple variants of the DRD3, but not BDNF gene, influence age-at-onset of schizophrenia.

scientific article published in December 2007

Nabiximols combined with motivational enhancement/cognitive behavioral therapy for the treatment of cannabis dependence: A pilot randomized clinical trial

scientific article published on 31 January 2018

Neuroadaptations to hyperdopaminergia in dopamine D3 receptor-deficient mice.

scientific article published on 25 December 2004

Neuronal calcium sensor-1 deletion in the mouse decreases motivation and dopamine release in the nucleus accumbens

scientific article published on 28 December 2015

Neuronal circuitry underlying the impact of D3 receptor ligands in drug addiction.

scientific article

Nicotine as a typical drug of abuse in experimental animals and humans.

scientific article

Nicotine induces conditioned place preferences over a large range of doses in rats.

scientific article

Nicotine pre-exposure does not potentiate the locomotor or rewarding effects of Delta-9-tetrahydrocannabinol in rats

scientific article published in March 2006

Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction

scientific article published on 2 February 2012

Noradrenergic α1 Receptors as a Novel Target for the Treatment of Nicotine Addiction

Obesity and cannabis use: results from 2 representative national surveys

scientific article

Occupancy of Dopamine D3 and D2 Receptors by Buspirone: A [11C]-(+)-PHNO PET Study in Humans

scientific article published on 19 June 2015

Off-Label Use of Medications for Treatment of Benzodiazepine Use Disorder.

scientific article published on January 2015

Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis.

scientific article published on 22 March 2017

Pharmacotherapies for cannabis dependence

scientific article

Preliminary evaluation of a human laboratory model of impaired control over alcohol using intravenous alcohol self-administration.

scientific article published in August 2017

Presentation of smoking-associated cues does not elicit dopamine release after one-hour smoking abstinence: A [11C]-(+)-PHNO PET study

scientific article

Prevalence and correlates of major depressive episode in pregnant and postpartum women in the United States

scientific article published on 29 July 2011

Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol

scientific article published on 3 December 2015

Psychiatric disorders as vulnerability factors for nicotine addiction: what have we learned from animal models?

scientific article

Psychosocial and pharmacological interventions for the treatment of cannabis use disorder.

scientific article published on 12 February 2018

Psychosocial interventions for cannabis use disorder

scientific article

Recent methods for measuring dopamine D3 receptor occupancy in vivo: importance for drug development

scientific article

Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder.

scientific article published on November 2010

Repurposing buspirone for drug addiction treatment

scientific article published on 19 October 2012

Rimonabant, a CB1 antagonist, blocks nicotine-conditioned place preferences.

scientific article published in September 2004

Role of DRD3 in morphine-induced conditioned place preference using drd3-knockout mice

scientific article published in October 2004

Role of the dopamine D3 receptor in reactivity to cocaine-associated cues in mice

scientific article published in June 2002

Screening Medications for the Treatment of Cannabis Use Disorder

scientific article published on 10 March 2016

Screening and Treatment for Alcohol, Tobacco and Opioid Use Disorders: A Survey of Family Physicians across Ontario

scientific article

Self-reported psychotic disorders among Individuals with substance use disorders: findings from the National Epidemiologic Survey on Alcohol and Related Conditions

scientific article published on 27 September 2012

Smoking cessation guidelines: evidence-based recommendations of the French Health Products Safety Agency.

scientific article published in August 2005

Targeting the Endocannabinoid CB1 Receptor to Treat Body Weight Disorders: A Preclinical and Clinical Review of the Therapeutic Potential of Past and Present CB1 Drugs

scientific article published on 04 June 2020

Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers

scientific article published in PLoS ONE

The CB1 Neutral Antagonist AM4113 Retains the Therapeutic Efficacy of the Inverse Agonist Rimonabant for Nicotine Dependence and Weight Loss with Better Psychiatric Tolerability.

scientific article

The Impact of Selective Dopamine D2, D3 and D4 Ligands on the Rat Gambling Task

scientific article

The agranular and granular insula differentially contribute to gambling-like behavior on a rat slot machine task: effects of inactivation and local infusion of a dopamine D4 agonist on reward expectancy

scientific article published on 14 July 2016

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats

scientific article

The association between cannabis use and depression: a systematic review and meta-analysis of longitudinal studies.

scientific article

The dopamine D3 receptor and drug dependence: effects on reward or beyond?

scientific article

The dopamine D3 receptor, a quarter century later.

scientific article published on 7 September 2016

The endocannabinoid system as a target for addiction treatment: Trials and tribulations.

scientific article published on 28 May 2017

The endocannabinoid system: a new molecular target for the treatment of tobacco addiction.

scientific article

The fatty acid amide hydrolase C385A variant affects brain binding of the positron emission tomography tracer [11C]CURB.

scientific article published on 3 June 2015

The future of endocannabinoid-oriented clinical research after CB1 antagonists.

scientific article published on 20 March 2009

The potential role of dopamine D₃ receptor neurotransmission in cognition.

scientific article published on 20 June 2013

The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake

scientific article published on November 2011

The selective dopamine D3 receptor antagonist SB 277011-A, but not the partial agonist BP 897, blocks cue-induced reinstatement of nicotine-seeking.

scientific article published on 9 December 2009

Time-dependent neuroendocrine alterations and drug craving during the first month of abstinence in heroin addicts.

scientific article published in January 2009

Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach.

scientific article published on 17 October 2013

Validation of an extracerebral reference region approach for the quantification of brain nicotinic acetylcholine receptors in squirrel monkeys with PET and 2-18F-fluoro-A-85380.

scientific article published on 17 August 2007

Varenicline and Bupropion for Long-Term Smoking Cessation (the MATCH Study): Protocol for a Real-World, Pragmatic, Randomized Controlled Trial

scientific article published on 18 October 2018

Varenicline-Induced Elevation of Dopamine in Smokers: A Preliminary [(11)C]-(+)-PHNO PET Study.

scientific article published on 7 October 2015

What does addiction medicine expect from neuroscience? From genes and neurons to treatment responses.

scientific article published on 6 January 2016

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