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List of works by Trevor Lithgow

1H, 13C and 15N Resonance Assignments of the Cytosolic Domain of Tom20 from Arabidopsis thaliana

scientific article published in November 2005

<i>Neisseria gonorrhoeae</i>-derived outer membrane vesicles package β-lactamases to promote antibiotic resistance

scientific article published in 2022

A Functional Tom70 in the Human Parasite Blastocystis sp.: Implications for the Evolution of the Mitochondrial Import Apparatus

scientific article published on 22 September 2010

A SNARE required for retrograde transport to the endoplasmic reticulum

scientific article

A Small Tim Homohexamer in the Relict Mitochondrion of Cryptosporidium

scientific article published on 6 October 2011

A Toxic Fusion Protein Accumulating between the Mitochondrial Membranes Inhibits Protein Assemblyin Vivo

scientific article published on 25 December 1998

A bioinformatic strategy for the detection, classification and analysis of bacterial autotransporters

scientific article

A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway

scientific article

A complete set of SNAREs in yeast

scientific article

A comprehensive analysis of the Omp85/TpsB protein superfamily structural diversity, taxonomic occurrence, and evolution.

scientific article

A conserved proline residue is present in the transmembrane-spanning domain of Tom7 and other tail-anchored protein subunits of the TOM translocase

scientific article

A constitutive form of heat-shock protein 70 is located in the outer membranes of mitochondria from rat liver

scientific article published on 18 October 1993

A first glimpse at the structure of the TOM translocase from the mitochondrial outer membrane

scientific article

A mitochondrial protein affects cell morphology, mitochondrial segregation and virulence in Leishmania

scientific article

A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways

scientific article

A modular BAM complex in the outer membrane of the alpha-proteobacterium Caulobacter crescentus.

scientific article

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

scientific article

A reply to Preiss et al

scientific article published in August 1997

An Escherichia coli gene showing a potential ancestral relationship to the genes for the mitochondrial import site proteins ISP42 and MOM38.

scientific article published on December 1993

An essential novel component of the noncanonical mitochondrial outer membrane protein import system of trypanosomatids

scientific article

An investigation into the Omp85 protein BamK in hypervirulent Klebsiella pneumoniae , and its role in outer membrane biogenesis

scientific article published on 19 September 2018

Ancestral and derived protein import pathways in the mitochondrion of Reclinomonas americana

scientific article (publication date: May 2011)

Antibacterial poly(ethylene glycol) hydrogels from combined epoxy-amine and thiol-ene click reaction

scientific article published on 16 September 2015

Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms

scientific article published on 21 December 2015

Assembling the mitochondrial outer membrane

scientific article

Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS

scientific article

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA.

scientific article published on 14 May 2015

Assembly of β-barrel proteins into bacterial outer membranes

scientific article

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

scientific article published on 27 May 2019

Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

scientific article published on 1 August 2019

Back to basics: a revealing secondary reduction of the mitochondrial protein import pathway in diverse intracellular parasites

scientific article published on 16 February 2012

Bacterial Proteins Predisposed for Targeting to Mitochondria

scientific article published in April 2004

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

scientific article

Bastion6: a bioinformatics approach for accurate prediction of type VI secreted effectors.

scientific article published on 14 March 2018

Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae

scientific article

Both the p33 and p55 subunits of the Helicobacter pylori VacA toxin are targeted to mammalian mitochondria.

scientific article

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

scientific article

Comprehensive assessment and performance improvement of effector protein predictors for bacterial secretion systems III, IV and VI.

scientific article

Conserved Features in the Structure, Mechanism, and Biogenesis of the Inverse Autotransporter Protein Family

scientific article

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module

scientific article published on 5 August 2015

Conserved motifs reveal details of ancestry and structure in the small TIM chaperones of the mitochondrial intermembrane space.

scientific article

Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space

scientific article

Constraints on lateral gene transfer in promoting fimbrial usher protein diversity and function

scientific article published in November 2017

Convergent Evolution of Receptors for Protein Import into Mitochondria

scientific article published in February 2006

Correction for Nguyen et al., "Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers".

scientific article published on 2 January 2018

Defining Membrane Protein Localization by Isopycnic Density Gradients

scientific article published on January 2017

Delivery of nascent polypeptides to the mitochondrial surface

scientific article

Determination of the molecular basis for coprogen import by Gram-negative bacteria

scientific article published on 05 April 2019

Discovery of an archetypal protein transport system in bacterial outer membranes.

scientific article

Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast

scientific article

Do cytosolic factors prevent promiscuity at the membrane surface?

scientific article published on 23 August 1993

Domain Stealing by Receptors in a Protein Transport Complex

scientific article published on 22 June 2007

Domain organization of the monomeric form of the Tom70 mitochondrial import receptor

scientific article published on 7 April 2009

Dynamic association of BAM complex modules includes surface exposure of the lipoprotein BamC.

scientific article

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine.

scientific article

Efficient construction of unmarked recombinant mycobacteria using an improved system

scientific article published on 27 May 2014

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.

scientific article published on 24 February 2016

Emerging rules for effective antimicrobial coatings

scientific article published on 28 October 2013

Environmental stresses inhibit and stimulate different protein import pathways in plant mitochondria

scientific article published on July 2003

Erratum to “Domain Organization of the Monomeric Form of the Tom70 Mitochondrial Import Receptor” [J. Mol. Biol. 388 (2009) 1043–1058]

scientific article published in July 2009

Evidence of Distinct Channel Conformations and Substrate Binding Affinities for the Mitochondrial Outer Membrane Protein Translocase Pore Tom40.

scientific article

Evidence of a reduced and modified mitochondrial protein import apparatus in microsporidian mitosomes

scientific article

Evolution of macromolecular import pathways in mitochondria, hydrogenosomes and mitosomes

scientific article

Evolution of the Translocation and Assembly Module (TAM)

scientific article

Evolution of the molecular machines for protein import into mitochondria

scientific article published on July 2006

Evolution of the β-barrel assembly machinery ⬇️

scientific article published on September 6, 2012

Extensively Drug-Resistant Klebsiella pneumoniae Causing Nosocomial Bloodstream Infections in China: Molecular Investigation of Antibiotic Resistance Determinants, Informing Therapy, and Clinical Outcomes.

scientific article

Filamentous phages: masters of a microbial sharing economy

scientific article published on 05 April 2019

Formation and function of bacterial organelles

scientific article published on 24 July 2020

Functional cooperation of mitochondrial protein import receptors in yeast.

scientific article

FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants

article

Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa.

scientific article published in April 2018

Giardia mitosomes and trichomonad hydrogenosomes share a common mode of protein targeting

scientific article

GlycoMine(struct): a new bioinformatics tool for highly accurate mapping of the human N-linked and O-linked glycoproteomes by incorporating structural features

scientific article published on 06 October 2016

High-level expression of a mitochondrial enzyme, ornithine transcarbamylase from rat liver, in a baculovirus expression system

scientific article published on July 1991

Highways for protein delivery to the mitochondria

scientific article published on April 1997

How do plant mitochondria avoid importing chloroplast proteins? Components of the import apparatus Tom20 and Tom22 from Arabidopsis differ from their fungal counterparts

scientific article

Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1

scientific article published on 15 June 2006

Identification of BamC on the Surface of E. coli

scientific article published in January 2015

Identification of a GTP-binding protein in the contact sites between inner and outer mitochondrial membranes

scientific article published in November 1991

Import and folding of proteins by mitochondria

scientific article published on January 1995

Import of the Cytochrome Oxidase Subunit Va Precursor into Yeast Mitochondria Is Mediated by the Outer Membrane Receptor Mas20p

scientific article published in Journal of Biological Chemistry

Importing mitochondrial proteins: machineries and mechanisms

scientific article (publication date: 21 August 2009)

Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae

scientific article

Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation

scientific article published on 13 August 2009

Knowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites

scientific article

Legionella pneumophila secretes a mitochondrial carrier protein during infection

scientific article

Light-triggered release of ciprofloxacin from an in situ forming click hydrogel for antibacterial wound dressings

scientific article published in 2015

Mas37p, a novel receptor subunit for protein import into mitochondria.

scientific article published on April 1995

Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane

scientific article

Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage

scientific article published on 25 August 2021

Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium.

scientific article

Mft52, an Acid-bristle Protein in the Cytosol That Delivers Precursor Proteins to Yeast Mitochondria

scientific article published in Journal of Biological Chemistry

Microsporidian mitosomes retain elements of the general mitochondrial targeting system

scholarly article

Minor modifications and major adaptations: the evolution of molecular machines driving mitochondrial protein import

scientific article published on 24 July 2010

Mitochondrial Biogenesis: Sorting Mechanisms Cooperate in ABC Transporter Assembly

scientific article published in July 2010

Mitochondrial FtsZ in a chromophyte alga.

scientific article

Mitochondrial Preprotein Translocase of Trypanosomatids Has a Bacterial Origin

scientific article published in October 2011

Mitochondrial Release of Pro-apoptotic Proteins

scientific article published on 9 November 2004

Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria

scientific article published in January 2015

Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence

scientific article published on 27 January 2012

Modifications and Innovations in the Evolution of Mitochondrial Protein Import Pathways

scientific article published on 8 October 2013

Molecular architecture and function of the Omp85 family of proteins

scientific article

Molecular architecture of the active mitochondrial protein gate

scientific article

MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression ⬇️

scientific article

Nanomechanics measurements of live bacteria reveal a mechanism for bacterial cell protection: the polysaccharide capsule in Klebsiella is a responsive polymer hydrogel that adapts to osmotic stress

scientific article published in 2013

Of linkers and autochaperones: an unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion

scientific article

Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.

scientific article

POSSUM: a bioinformatics toolkit for generating numerical sequence feature descriptors based on PSSM profiles.

scientific article published in September 2017

PUF proteins: repression, activation and mRNA localization

scientific article

Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20

scientific article (publication date: 18 March 2005)

Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan

scientific article

Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly

scientific article published on 06 February 2019

Positive autoregulation of mrkHI by the cyclic di-GMP-dependent MrkH protein in the biofilm regulatory circuit of Klebsiella pneumoniae

scientific article

Prebiotic-chemistry inspired polymer coatings for biomedical and material science applications

scientific article published in November 2015

Prechaperonin 60 and preornithine transcarbamylase share components of the import apparatus but have distinct maturation pathways in rat liver mitochondria

scientific article published in February 1993

Primary structure of mammalian ribosomal protein S6

scientific article published in January 1988

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

scientific article

Protease-associated import systems are widespread in Gram-negative bacteria

scientific article published on 15 October 2019

Protein hijacking: key proteins held captive against their will

scientific article published on February 2004

Protein import into mitochondria: origins and functions today (review).

scientific article

Protein secretion and outer membrane assembly in Alphaproteobacteria

scientific article

Protein structure and function by the sea

scientific article

Protein targeting: entropy, energetics and modular machines

scientific article

Quokka: a comprehensive tool for rapid and accurate prediction of kinase family-specific phosphorylation sites in the human proteome

scientific article published on 01 December 2018

RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin.

scientific article

Re-assessing the locations of components of the classical vesicle-mediated trafficking machinery in transfected Plasmodium falciparum

scientific article (publication date: August 2007)

Recognition of mitochondrial targeting sequences by the import receptors Tom20 and Tom22.

scientific article published on 16 November 2010

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

scientific article

Reconstitution of membrane proteins into model membranes: seeking better ways to retain protein activities

scientific article

Reconstitution of the initial steps of mitochondrial protein import

scientific article published in August 1995

Reductive evolution in outer membrane protein biogenesis has not compromised cell surface complexity in Helicobacter pylori

scientific article published on 21 October 2017

Response to Zarsky et al

scientific article published in June 2012

Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

scientific article published on August 1999

Seaside transportation--from structure to function of translocation machines

scientific article published on 14 June 2013

SecretEPDB: a comprehensive web-based resource for secreted effector proteins of the bacterial types III, IV and VI secretion systems

scientific article published on 23 January 2017

Self-assembly of ciprofloxacin and a tripeptide into an antimicrobial nanostructured hydrogel.

scientific article published on 17 February 2013

Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome

scientific article

Structural Basis of Type 2 Secretion System Engagement between the Inner and Outer Bacterial Membranes

scientific article published on 17 October 2017

Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

scientific article

Structural insight into the biogenesis of β-barrel membrane proteins

scientific article

Structure, topology and function of the translocase of the outer membrane of mitochondria

scientific article published on 03 January 2008

Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria

scientific article

Systematic analysis and prediction of type IV secreted effector proteins by machine learning approaches.

scientific article published on 27 November 2017

Systems biology: the next frontier for bioinformatics

scientific article

TOM and SAM Machineries in Mitochondrial Protein Import and Outer Membrane Biogenesis

scientific article published in 2007

Targeting of C-Terminal (Tail)-Anchored Proteins: Understanding how Cytoplasmic Activities are Anchored to Intracellular Membranes

scientific article published in January 2001

Targeting of Neisserial PorB to the mitochondrial outer membrane: an insight on the evolution of β-barrel protein assembly machines

scientific article

Targeting of proteins to mitochondria

scientific article

Targeting of tail-anchored proteins to yeast mitochondria in vivo

scientific article

The C-terminal TPR Domain of Tom70 Defines a Family of Mitochondrial Protein Import Receptors Found only in Animals and Fungi

scientific article published in May 2006

The J-protein family: modulating protein assembly, disassembly and translocation

scientific article

The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria.

scientific article

The Structure of a Conserved Domain of TamB Reveals a Hydrophobic β Taco Fold

scientific article published on 3 November 2017

The TPR domain of BepA is required for productive interaction with substrate proteins and the β-barrel assembly machinery complex

scientific article published on 27 September 2017

The Tom channel in the mitochondrial outer membrane: alive and kicking

scientific article

The Transmembrane Segment of Tom20 Is Recognized by Mim1 for Docking to the Mitochondrial TOM Complex

scientific article published in February 2008

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

scientific article published on 01 May 2018

The Yeast Mitochondrial Protein Import Receptor Mas20p Binds Precursor Proteins through Electrostatic Interaction with the Positively Charged Presequence

scientific article published in Journal of Biological Chemistry

The architecture and stabilisation of flagellotropic tailed bacteriophages

scientific article published on 27 July 2020

The core components of organelle biogenesis and membrane transport in the hydrogenosomes of Trichomonas vaginalis

scientific article published on 15 September 2011

The crystal structure of the TonB-dependent transporter YncD reveals a positively charged substrate-binding site

scientific article published on 27 April 2020

The direct route: a simplified pathway for protein import into the mitochondrion of trypanosomes

scientific article published on January 2008

The essentials of protein import in the degenerate mitochondrion of Entamoeba histolytica

scientific article

The evolution of new lipoprotein subunits of the bacterial outer membrane BAM complex.

scientific article

The first steps of protein import into mitochondria

scientific article published on February 1997

The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi-like protein tail fibre

scientific article published on 09 October 2019

The major surface-associated saccharides of Klebsiella pneumoniae contribute to host cell association

scientific article

The minimal proteome in the reduced mitochondrion of the parasitic protist Giardia intestinalis

scientific article

The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins

scientific article

The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast

scientific article

The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes

scientific article published on 18 January 2002

The modular nature of the β-barrel assembly machinery, illustrated in Borrelia burgdorferi

scientific article

The nascent polypeptide-associated complex (NAC) promotes interaction of ribosomes with the mitochondrial surface in vivo

scientific article published on 18 March 2002

The peripheral membrane subunits of the SAM complex function codependently in mitochondrial outer membrane biogenesis

scientific article

The protein encoded by theMFT1gene is a targeting factor for mitochondrial precursor proteins, and not a core ribosomal protein

scientific article published on 28 April 1997

The protein import channel in the outer mitosomal membrane of Giardia intestinalis

scientific article published on 16 June 2009

The protein import receptor of mitochondria

scientific article published in March 1995

The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane.

scientific article published on April 1994

The reducible complexity of a mitochondrial molecular machine

scientific article

The single mitochondrial porin of Trypanosoma brucei is the main metabolite transporter in the outer mitochondrial membrane

scientific article

The structure and membrane topography of the Vibrio-type secretin complex from the T2SS of enteropathogenic Escherichia coli (EPEC).

scientific article published on 30 October 2017

The three domains of the mitochondrial outer membrane protein Mim1 have discrete functions in assembly of the TOM complex

scientific article published on 2 April 2009

The twists and turns of Maurer's cleft trafficking in P. falciparum-infected erythrocytes

scientific article published on 10 December 2007

The type II secretion system and its ubiquitous lipoprotein substrate, SslE, are required for biofilm formation and virulence of enteropathogenic Escherichia coli

scientific article

The yeast PUF protein Puf5 has Pop2-independent roles in response to DNA replication stress

scientific article

The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo.

scientific article

The β-Barrel Assembly Machinery Complex

scientific article published on January 2015

Tinkering Inside the Organelle

scientific article

Tom22', an 8-kDa trans-site receptor in plants and protozoans, is a conserved feature of the TOM complex that appeared early in the evolution of eukaryotes

scientific article published on 21 May 2004

Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins

scientific article

Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein

scientific article

Using hidden markov models to discover new protein transport machines

scientific article

Yeast mitochondria lacking the two import receptors Mas20p and Mas70p can efficiently and specifically import precursor proteins

scientific article published in Journal of Biological Chemistry

Zim17, a novel zinc finger protein essential for protein import into mitochondria

scientific article

cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria

scientific article published on 12 February 2019

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