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List of works by Katleen De Preter

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

scientific article
Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

scientific article published on 18 August 2010
Mutational dynamics between primary and relapse neuroblastomas.

scientific article
Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

scientific article
Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay

scientific article published in February 2002
Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

scientific article
Evaluation of qPCR curve analysis methods for reliable biomarker discovery: bias, resolution, precision, and implications

scientific article
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.

scientific article
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.

scientific article published in July 2012
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours.

scientific article published on 12 April 2010
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

scientific article published in January 2006
Measurable impact of RNA quality on gene expression results from quantitative PCR.

scientific article published on 11 February 2011
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

scientific article
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays

scientific article
miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples

scientific article
ArrayCGH-based classification of neuroblastoma into genomic subgroups

scientific article published on December 2007
Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature

scientific article
High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma

scientific article
MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells

scientific article
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

scientific article published on 26 April 2013
Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma

scientific article
Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma

scientific article
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers

scientific article
Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions

scientific article published on 16 March 2008
A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.

scientific article published on September 2014
Asthma inflammatory phenotypes show differential microRNA expression in sputum

scientific article published in May 2016
Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

scientific article published on 27 October 2011
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

scientific article
Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

scientific article published on 22 September 2009
Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds

scientific article
Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma

scientific journal article
Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

scientific article
ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value

scientific article published in January 2003
Copy number alterations and copy number variation in cancer: close encounters of the bad kind

scientific article published on January 2008
ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation

scientific article
MYCN-targeting miRNAs are predominantly downregulated during MYCN-driven neuroblastoma tumor formation

scientific article published on March 10, 2015
The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

scientific article published on 27 July 2009
Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma

scientific article published on 12 December 2013
A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

scientific article (publication date: 2013)
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes

scientific journal article
Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome

scientific article
CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

scientific article
Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

scientific article
Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas

scientific article
A 6-gene signature identifies four molecular subgroups of neuroblastoma

scientific article published on 14 April 2011
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

scientific article
Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma

scientific article
Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

scientific article published on September 2007
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

scientific article (publication date: July 2007)
External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data

scientific article

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