List of works by Katleen De Preter

A 6-gene signature identifies four molecular subgroups of neuroblastoma

scientific article published on 14 April 2011

A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.

scientific article published on September 2014

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

scientific article (publication date: July 2007)

A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

scientific article (publication date: 2013)

Aberrant splicing of the PTPRD gene mimics microdeletions identified at this locus in neuroblastomas

scientific article published on March 2008

Accelerating drug development for neuroblastoma - New Drug Development Strategy: an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Euro

scientific article published on 12 June 2017

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

scientific article

Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature

scientific article

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

scientific article

Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma

scientific article

An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours.

scientific article published on 12 April 2010

Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells

scientific article

ArrayCGH-based classification of neuroblastoma into genomic subgroups

scientific article published on December 2007

Asthma inflammatory phenotypes show differential microRNA expression in sputum

scientific article published in May 2016

Author Correction: Benchmarking of cell type deconvolution pipelines for transcriptomics data

scientific article published on 02 December 2020

Benchmarking of cell type deconvolution pipelines for transcriptomics data

scientific article published on 06 November 2020

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

scientific article

Cancer gene prioritization for targeted resequencing using FitSNP scores

scientific article

Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells

scientific article published on 19 October 2016

Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma

scientific article

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons

scientific article

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

scientific article published on 22 September 2009

Copy number alterations and copy number variation in cancer: close encounters of the bad kind

scientific article published on January 2008

Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

scientific article published on 27 October 2011

DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth

scientific article published on 03 February 2019

Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

scientific article published on September 2007

Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma

scientific journal article

Different Sarcocystis spp. are present in bovine eosinophilic myositis

scientific article

ERBB3 is a marker of a ganglioneuroblastoma/ganglioneuroma-like expression profile in neuroblastic tumours.

scientific article published on 08 July 2013

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

scientific article published on 14 May 2011

Evaluation of qPCR curve analysis methods for reliable biomarker discovery: bias, resolution, precision, and implications

scientific article

Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome

scientific article

External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data

scientific article

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes

scientific journal article

From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma

scientific article published in 2021

Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma

scientific article

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers

scientific article

Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome

scientific article published on 19 October 2020

High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma

scientific article

High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors

scientific article published on February 2007

Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma

scientific article published on 12 December 2013

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

scientific article

ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value

scientific article published in January 2003

Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics

scientific article published in March 2008

Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas

scientific article

Identification of tumoral glial precursor cells in neuroblastoma.

scientific article published on 17 August 2011

Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use.

scientific article published on 20 February 2015

Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

scientific article published on 20 November 2018

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization.

scientific article

Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma

scientific article published on 13 June 2008

MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells

scientific article

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

scientific article published on 26 April 2013

MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma

scientific article published on 26 June 2015

MYCN-targeting miRNAs are predominantly downregulated during MYCN‑driven neuroblastoma tumor formation

scientific article published on March 2015

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.

scientific article

Measurable impact of RNA quality on gene expression results from quantitative PCR.

scientific article published on 11 February 2011

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

scientific article published on 18 August 2010

Meta-mining of copy number profiles of high-risk neuroblastoma tumors

scientific article published on 30 October 2018

Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds

scientific article

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

scientific article published on 6 December 2015

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

scientific article

Mutational dynamics between primary and relapse neuroblastomas.

scientific article

N-cadherin in neuroblastoma disease: expression and clinical significance

scientific article

Neuroblastoma genetics and phenotype: a tale of heterogeneity

scientific article published on 04 August 2011

No Evidence for Correlation of DDX1 Gene Amplification With Improved Survival Probability in Patients With MYCN-Amplified Neuroblastomas

article

No evidence for involvement of SDHD in neuroblastoma pathogenesis

scientific article

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

scientific article

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

scientific article

Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions

scientific article published on 16 March 2008

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

scientific article

Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay

scientific article published in February 2002

SCORPIUS improves trajectory inference and identifies novel modules in dendritic cell development

article

Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.

scientific article published in July 2012

Targeting tachykinin receptors in neuroblastoma

scientific article

The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

scientific article published on 27 July 2009

The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumors

scientific article published on October 2010

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

scientific article

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

scientific article

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

scientific article

ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation

scientific article

When DNA gets in the way: A cautionary note for DNA contamination in extracellular RNA-seq studies

scientific article published on 01 August 2020

Zipper plot: visualizing transcriptional activity of genomic regions

scholarly article published 23 September 2016

arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays

scientific article

miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples

scientific article

Paulina is supported by:

About Paulina

Help