List of works - Ettore Appella

A CD8+ T cell heptaepitope minigene vaccine induces protective immunity against Chlamydia pneumoniae

scientific article published on May 2005

A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection

scientific article

A rational strategy to design multiepitope immunogens based on multiple Th lymphocyte epitopes

scientific article published in June 2002

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

scientific article (publication date: June 2002)

Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex

scientific article

Charge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking

scientific article

Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters.

scientific article

Cooperative interactions at the SLP-76 complex are critical for actin polymerization

scientific article

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

scientific article

Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartment

scientific article

ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation

scientific article published in August 2005

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

scientific article

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation ⬇️

scientific article

Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control

scientific article

Modulation of p53 function by SET8-mediated methylation at lysine 382

scientific article

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

scientific article

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1

scientific article

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins

scientific article

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes

scientific article

Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint

scientific article

Single MHC Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding

scientific article

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

scientific article

Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation

scientific article

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53

scientific article published on 01 June 2006

Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.

scientific article

Substrate specificity of the human protein phosphatase 2Cdelta, Wip1

scientific article (publication date: 12 April 2005)

The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression ⬇️

scientific article

The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair

scientific article

The processing of Holliday junctions by BLM and WRN helicases is regulated by p53

scientific article (publication date: 30 August 2002)

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity

scientific article

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

scientific article

List of works by Ettore Appella

A CD8+ T cell heptaepitope minigene vaccine induces protective immunity against Chlamydia pneumoniae

A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection

A rational strategy to design multiepitope immunogens based on multiple Th lymphocyte epitopes

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex

Charge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm trafficking

Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters.

Cooperative interactions at the SLP-76 complex are critical for actin polymerization

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartment

ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation ⬇️

Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control

Modulation of p53 function by SET8-mediated methylation at lysine 382

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes

Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint

Single MHC Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53

Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.

Substrate specificity of the human protein phosphatase 2Cdelta, Wip1

The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression ⬇️

The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair

The processing of Holliday junctions by BLM and WRN helicases is regulated by p53

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression