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List of works by Marc Ladanyi

<i>BRAF</i> Mutation Analysis of Fine-Needle Aspiration Biopsies of Papillary Thyroid Carcinoma: Impact on Diagnosis and Prognosis ⬇️

scientific article published on 09 December 2011

A Distinctive Subset of PEComas Harbors TFE3 Gene Fusions ⬇️

scientific article published on October 1, 2010

A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer

scientific article published on 16 December 2015

A Subset of Malignant Mesotheliomas in Young Adults Are Associated With Recurrent EWSR1/FUS-ATF1 Fusions

scientific article published on 12 May 2017

A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23).

scientific article published in August 2003

A pilot study of volume measurement as a method of tumor response evaluation to aid biomarker development

scientific article

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

scientific article

A synovial sarcoma-specific preoperative nomogram supports a survival benefit to ifosfamide-based chemotherapy and improves risk stratification for patients

scientific article published on December 2008

ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer ⬇️

scientific article published on May 31, 2013

ALK-Rearranged Lung Cancer: Adenosquamous Lung Cancer Masquerading as Pure Squamous Carcinoma ⬇️

scientific article published on April 1, 2012

Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma

scientific article published on April 2003

Absence of common activating mutations of the epidermal growth factor receptor gene in thyroid cancers from American and Japanese patients

scientific article published on 24 August 2011

Accelerating Discovery of Functional Mutant Alleles in Cancer

scientific article published on 15 December 2017

Acquired Resistance of EGFR-Mutant Lung Cancer to a T790M-Specific EGFR Inhibitor: Emergence of a Third Mutation (C797S) in the EGFR Tyrosine Kinase Domain

scientific article

Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: distinct natural history of patients with tumors harboring the T790M mutation

scientific article

Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma

scientific article

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer ⬇️

scientific article published on July 1, 2012

Advances in sarcoma genomics and new therapeutic targets

scientific article

Aggressive Hematopoietic Malignancy Characterized by Biallelic Loss of SMARCB1

scientific article published on 28 October 2020

Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene

scientific article

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer

scientific article published on 7 October 2015

Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report

scientific article

Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers

scientific article

Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

scientific article published on 23 December 2016

Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR.

scientific article published on 21 January 2010

Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors

article

Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas

scientific article

BAP1 missense mutation c.2054 A>T (p.E685V) completely disrupts normal splicing through creation of a novel 5' splice site in a human mesothelioma cell line

scientific article published on April 2015

BCOR is a robust diagnostic immunohistochemical marker of genetically diverse high-grade endometrial stromal sarcoma, including tumors exhibiting variant morphology

scientific article

Broad, Hybrid Capture-Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches

scientific article published on 07 January 2015

CRKL as a Lung Cancer Oncogene and Mediator of Acquired Resistance to EGFR Inhibitors: Is It All That It Is Cracked Up to Be? ⬇️

scientific article published on December 1, 2011

Cancer Genomics: Large-Scale Projects Translate into Therapeutic Advances

scientific article published on 27 December 2016

Cancer biology and genomics: translating discoveries, transforming pathology

scientific article published on January 2011

Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma

scientific article

Characterizing the cancer genome in lung adenocarcinoma

scientific article

Clarifying the Spectrum of Driver Oncogene Mutations in Biomarker-Verified Squamous Carcinoma of Lung: Lack of EGFR/KRAS and Presence of PIK3CA/AKT1 Mutations ⬇️

scientific article published on January 6, 2012

Clinical Application of Picodroplet Digital PCR Technology for Rapid Detection of EGFR T790M in Next-Generation Sequencing Libraries and DNA from Limited Tumor Samples

scientific article

Clinical Characteristics of Patients With Lung Adenocarcinomas Harboring BRAF Mutations ⬇️

scientific article published on April 11, 2011

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer

scientific article

Clinical cancer genomics: how soon is now? ⬇️

scientific article published on October 28, 2010

Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib

scientific article published in February 2006

Clinical heterogeneity of Xp11 translocation renal cell carcinoma: impact of fusion subtype, age, and stage

scientific article published on 06 December 2013

Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation ⬇️

scientific article published on April 28, 2003

Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy

scientific article published on May 2011

Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling

scientific article published on December 2011

Combining integrated genomics and functional genomics to dissect the biology of a cancer‐associated, aberrant transcription factor, the ASPSCR1–TFE3 fusion oncoprotein ⬇️

scientific article published on March 5, 2013

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization

scientific article published on 31 May 2016

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

article

Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing

scientific article

Core needle lung biopsy specimens: adequacy for EGFR and KRAS mutational analysis

scientific article published on January 2010

Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma

scientific article published on April 2009

DOK2 inhibits EGFR-mutated lung adenocarcinoma

scientific article

Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma

scientific article published on 28 August 2016

Desmoplastic small round cell tumor 20 years after its discovery

scientific article published on January 2015

Detection of EGFR mutations in plasma DNA from lung cancer patients by mass spectrometry genotyping is predictive of tumor EGFR status and response to EGFR inhibitors

scientific article published on 3 December 2010

Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping

scientific article

Differential expression of cathepsin K in neoplasms harboring TFE3 gene fusions

scientific article published on 20 May 2011

Distinct clinical course of EGFR-mutant resected lung cancers: results of testing of 1118 surgical specimens and effects of adjuvant gefitinib and erlotinib

scientific article published in December 2012

Distinct profile of driver mutations and clinical features in immunomarker-defined subsets of pulmonary large-cell carcinoma ⬇️

scientific article published on November 30, 2012

Distinctive neoplasms characterised by specific chromosomal translocations comprise a significant proportion of paediatric renal cell carcinomas

scientific article published on December 2003

Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas

scientific article published on October 2004

Driver mutations determine survival in smokers and never‐smokers with stage IIIB/IV lung adenocarcinomas ⬇️

scientific article published on May 17, 2012

E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma

scientific article

EGFR Kinase Domain Duplication (EGFR-KDD) Is a Novel Oncogenic Driver in Lung Cancer That Is Clinically Responsive to Afatinib

scientific article

EGFR exon 19 insertions: a new family of sensitizing EGFR mutations in lung adenocarcinoma

scientific article

EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations

scientific article published in August 2005

EGFR mutations in lung adenocarcinomas: clinical testing experience and relationship to EGFR gene copy number and immunohistochemical expression

scientific article published on 10 April 2008

EGFR mutations in small-cell lung cancers in patients who have never smoked.

scientific article

EWS-CREB1: a recurrent variant fusion in clear cell sarcoma--association with gastrointestinal location and absence of melanocytic differentiation.

scientific article

EWS-FLI1 and Ewing's sarcoma: recent molecular data and new insights.

scientific article

EWS-WT1 oncoprotein activates neuronal reprogramming factor ASCL1 and promotes neural differentiation

scientific article

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

scientific article

Erratum: Advances in sarcoma genomics and new therapeutic targets

scientific article published on 22 July 2011

Evidence against a role for SV40 infection in human mesotheliomas and high risk of false-positive PCR results owing to presence of SV40 sequences in common laboratory plasmids

scientific article published in September 2004

Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse

scientific article published in January 2005

Ewing tumors that do not overexpress BMI-1 are a distinct molecular subclass with variant biology: a report from the Children's Oncology Group

scientific article

Exceptional responders with invasive mucinous adenocarcinomas: a phase 2 trial of bortezomib in patients with KRAS G12D-mutant lung cancers.

scientific article

Expression of F-actin-capping protein subunit beta, CAPZB, is associated with cell growth and motility in epithelioid sarcoma

scientific article

Expression of SSX genes in the neoplastic cells of Hodgkin's lymphoma

scientific article published on May 2002

Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation

scientific article published on November 2002

Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma

scientific article

Functional copy-number alterations in cancer

scientific article

GENO-35NGS-BASED MSK-IMPACT ANALYSIS REVEALS SPECIFIC GENETIC ALTERATIONS IN RECURRENT GLIOBLASTOMA.

scientific article

Genetic predictors of MEK dependence in non-small cell lung cancer

scientific article

Genomic aberrations frequently alter chromatin regulatory genes in chordoma

scientific article

Genomic and mutational profiling to assess clonal relationships between multiple non-small cell lung cancers

scientific article

Genomics Traces Carcinogen Fingerprints ⬇️

scientific article published on August 7, 2013

Germline EGFR T790M mutation found in multiple members of a familial cohort

scientific article published on April 2014

Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.

scientific article

Glioneuronal tumor with neuropil-like islands (GTNI): a report of 8 cases with chromosome 1p/19q deletion analysis

scientific article published in August 2007

Global gene expression profiling of pleural mesotheliomas: overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction

scientific article

HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: a single-institution experience of 2,279 cases and comparison of dual-color and single-color scoring

scientific article published in May 2004

HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation

scientific article published on 5 September 2012

Harnessing Clinical Sequencing Data for Survival Stratification of Patients with Metastatic Lung Adenocarcinomas

scientific article published on 28 March 2019

Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases

scientific article

High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)

scientific article

High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas ⬇️

scientific article published on July 14, 2011

Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration

scientific article published on 30 March 2009

Identification of DOK genes as lung tumor suppressors

scientific article

Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions

scientific article

Identification of NTRK3 Fusions in Childhood Melanocytic Neoplasms

scientific article published in May 2017

Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target

scientific article

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

scientific article

Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma ⬇️

scientific article published on 03 June 2013

Imatinib mesylate in Philadelphia chromosome-positive leukemia of childhood

scientific article

Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients.

scientific article

Impact of polysomy 17 on HER-2/neu immunohistochemistry in breast carcinomas without HER-2/neu gene amplification

scientific article published on August 2003

Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations

scientific article published on March 2011

Implications of P16/CDKN2A deletion in pleural mesotheliomas

scientific article

Important recent insights into the genetics and biology of malignant pleural mesothelioma

scientific article published on November 2012

Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas

scientific article published on 11 April 2011

Insulin-Like Growth Factor 1 Receptor as a Therapeutic Target in Ewing Sarcoma: Lack of Consistent Upregulation or Recurrent Mutation and a Review of the Clinical Trial Literature ⬇️

scientific article published on January 28, 2013

Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center

scientific article

Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis

scientific article

Integrative subtype discovery in glioblastoma using iCluster

scientific article

JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors

scientific article published on 29 March 2016

KRAS mutational testing in the selection of patients for EGFR-targeted therapies

scientific article

KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

scientific article

KRAS mutations are associated with solid growth pattern and tumor-infiltrating leukocytes in lung adenocarcinoma ⬇️

scientific article published on April 26, 2013

KRAS mutations: an old oncogene becomes a new predictive biomarker

scientific article published on 02 October 2008

Loss of BAP1 as a candidate predictive biomarker for immunotherapy of mesothelioma

Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond

scientific article published on May 2008

Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.

scientific article

MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Associated with Smoking

scientific article

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

scientific article

Maintained sensitivity to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer recurring after adjuvant erlotinib or gefitinib

scientific article published on 10 August 2011

Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression

scientific article published on 17 November 2015

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

scientific article published on 20 March 2015

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus

scientific article

Molecular Confirmation of t(6;11)(p21;q12) Renal Cell Carcinoma in Archival Paraffin-embedded Material Using a Break-apart TFEB FISH Assay Expands its Clinicopathologic Spectrum ⬇️

scientific article published on October 1, 2012

Molecular Detection of JAZF1-JJAZ1 Gene Fusion in Endometrial Stromal Neoplasms with Classic and Variant Histology

scientific article (publication date: February 2004)

Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand (PD-L)-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing

scientific article published on 16 January 2018

Molecular Pathogenesis of Ewing Sarcoma: New Therapeutic and Transcriptional Targets ⬇️

scientific article published on September 19, 2011

Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors

article

Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib

scientific article

Molecular characteristics predict clinical outcomes: prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene

scientific article published on 10 May 2011

Molecular detection of JAZF1-JJAZ1 gene fusion in endometrial stromal neoplasms with classic and variant histology: evidence for genetic heterogeneity

scientific article (publication date: February 2004)

Molecular diagnosis of clear cell sarcoma: detection of EWS-ATF1 and MITF-M transcripts and histopathological and ultrastructural analysis of 12 cases

scientific article published in February 2002

Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers

scientific article

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors

scientific article

Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular

scientific article

Morphologic features of adenocarcinoma of the lung predictive of response to the epidermal growth factor receptor kinase inhibitors erlotinib and gefitinib

scientific article

Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience

scientific article published on May 2015

Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.

scientific article

NCCN Task Force Report: Evaluating the Clinical Utility of Tumor Markers in Oncology ⬇️

scientific article published on November 1, 2011

New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer

scientific article

New strategies in pleural mesothelioma: BAP1 and NF2 as novel targets for therapeutic development and risk assessment

scientific article

Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status: Clinical Validation in the Context of a Hybrid Capture-Based, Comprehensive Solid Tumor Genomic Profiling Assay

scientific article published on 24 December 2016

Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases

scientific article

Nonrandom cell-cycle timing of a somatic chromosomal translocation: The t(X;17) of alveolar soft-part sarcoma occurs in G2.

scientific article

Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors

scientific article

Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma

scientific article published on July 2008

Novel markers of subclinical disease for Ewing family tumors from gene expression profiling

scientific article published on December 2007

Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling

scientific article published in 2022

Oncogene Mutation Profiling of Pediatric Solid Tumors Reveals Significant Subsets of Embryonal Rhabdomyosarcoma and Neuroblastoma with Mutated Genes in Growth Signaling Pathways ⬇️

scientific article published on December 5, 2011

Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling

scientific article

Optimizing the sequence of anti-EGFR-targeted therapy in EGFR-mutant lung cancer

scientific article

PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation

scientific article

PDGF Receptor Alpha Is an Alternative Mediator of Rapamycin-Induced Akt Activation: Implications for Combination Targeted Therapy of Synovial Sarcoma ⬇️

scientific article published on July 10, 2012

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

scientific article

PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma.

scientific article

PRCC-TFE3 renal carcinomas: morphologic, immunohistochemical, ultrastructural, and molecular analysis of an entity associated with the t(X;1)(p11.2;q21).

scientific article

Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions

scientific article published on 17 July 2017

Pattern discovery and cancer gene identification in integrated cancer genomic data

scientific article

Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials

scientific article

Primary Lung Adenocarcinomas in Children and Adolescents Treated for Pediatric Malignancies ⬇️

scientific article published on November 1, 2010

Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas

scientific article published on March 2015

Proteasome Addiction Defined in Ewing Sarcoma Is Effectively Targeted by a Novel Class of 19S Proteasome Inhibitors

scientific article

Pulmonary large cell neuroendocrine carcinoma with adenocarcinoma-like features: napsin A expression and genomic alterations

scientific article

Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates

scientific article published on 29 November 2013

RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer

scientific article published on 9 December 2014

RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition

scientific article published on 10 November 2017

RET inhibition in novel patient-derived models of RET-fusion positive lung adenocarcinoma reveals a role for MYC upregulation

scientific article published on 14 December 2020

Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas

scientific article published on August 2005

Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer

scientific article

Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay

scientific article

Recent advances in pediatric renal neoplasia

scientific article

Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer

scientific article

Reflex testing of resected stage I through III lung adenocarcinomas for EGFR and KRAS mutation: report on initial experience and clinical utility at a single center.

scientific article

Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR.

scientific article

Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas ⬇️

scientific article published on March 26, 2013

Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping

scientific article

SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer

scientific article published on 17 April 2017

SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma

scientific article published on July 2006

Screening for germline EGFR T790M mutations through lung cancer genotyping

scientific article

Secondary mutation in a coding mononucleotide tract in MSH6 causes loss of immunoexpression of MSH6 in colorectal carcinomas with MLH1/PMS2 deficiency

scientific article published on 24 August 2012

Serum- and glucocorticoid-regulated kinase 1 (SGK1) induction by the EWS/NOR1(NR4A3) fusion protein

scientific article published on 2 June 2006

Small-Cell Carcinoma With an Epidermal Growth Factor Receptor Mutation in a Never-Smoker With Gefitinib-Responsive Adenocarcinoma of the Lung ⬇️

scientific article published on September 1, 2010

Soft tissue sarcomas of adults: state of the translational science.

scientific article

Soluble mesothelin related peptides (SMRP) and osteopontin as protein biomarkers for malignant mesothelioma: analytical validation of ELISA based assays and characterization at mRNA and protein levels

scientific article

Somatic mutations affect key pathways in lung adenocarcinoma

scientific article

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

scientific article published on 29 November 2009

Sp1-mediated transcriptional control of fibroblast growth factor receptor 4 in sarcomas of skeletal muscle lineage

scientific article

Squamous-cell carcinomas of the lung: emerging biology, controversies, and the promise of targeted therapy ⬇️

scientific article published on October 1, 2012

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

scientific article

TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition

scientific article

TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies.

scientific article published in February 2007

The 2010 Fred W. Stewart award recipient: Julia A. Bridge, MD.

scientific article

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Journal of Pathology 2008 Jeremy Jass Prize for Research Excellence in Pathology

scientific article published in December 2009

The Molecular Pathology of Cancer: From Pan-genomics to Post-genomics

scientific article published on 13 February 2018

The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

scientific article published on 22 February 2018

The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

The evolution of molecular genetic pathology: advancing 20th-century diagnostic methods into potent tools for the new millennium

scientific article published on 10 October 2008

The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas

scientific article

The landscape of somatic copy-number alteration across human cancers

scientific article

The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation

scientific article published on 20 July 2009

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

scientific article

The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147.

scientific article

The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability ⬇️

scientific article

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

scientific journal article

Therapeutic Implications of Germline Testing in Patients With Advanced Cancers

scientific article published on 16 June 2021

Therapeutic Potential of Afatinib for Cancers with ERBB2 (HER2) Transmembrane Domain Mutations G660D and V659E.

scientific article published on 16 November 2017

Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes

scientific article published on 09 August 2017

Translocation carcinomas of the kidney

scientific article

Translocation-based molecular diagnosis of sarcomas.

scientific article

Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions

scientific article

Unsuspected collision of synchronous lung adenocarcinomas: a potential cause of aberrant driver mutation profiles

scientific article published on January 2014

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, an

scientific article published on 22 January 2018

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, an

scientific article published on 23 January 2018

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, an

scientific article published on 23 January 2018

Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas

scientific article published on 27 February 2006

Use of epidermal growth factor receptor/Kirsten rat sarcoma 2 viral oncogene homolog mutation testing to define clonal relationships among multiple lung adenocarcinomas: comparison with clinical guidelines

scientific article published on 17 April 2009

Use of touch imprint cytology as a simple method to enrich tumor cells for molecular analysis

scientific article published on 10 April 2013

Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs

scientific article

Utilization of a TFE3 Break-apart FISH Assay in a Renal Tumor Consultation Service ⬇️

scientific article published on August 1, 2013

Validation of the 2-DeltaDeltaCt calculation as an alternate method of data analysis for quantitative PCR of BCR-ABL P210 transcripts

scientific article

WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis

scientific article

William L Gerald, M. D., Ph.D., 1954-2008

scientific article published on January 2009

Xp11 Translocation Renal Cell Carcinoma (RCC): Extended Immunohistochemical Profile Emphasizing Novel RCC Markers ⬇️

scientific article published on September 1, 2010

Xp11 translocation renal cell carcinoma in adults: expanded clinical, pathologic, and genetic spectrum

scientific article published on August 2007

YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.

scientific article published on 6 June 2018

ZC3H7B-BCOR high-grade endometrial stromal sarcomas: a report of 17 cases of a newly defined entity

scientific article published in December 2017

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