List of works - Dontscho Kerjaschki

2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage

scientific article published on 20 June 2016

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes

scientific article published on June 2016

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

scientific article

A novel protein, densin, expressed by glomerular podocytes

scientific article

Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

scientific article published on July 2002

Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis

scientific article

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury ⬇️

scientific article published on May 23, 2011

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

scientific article

COL4A1 mutations and hereditary angiopathy, nephropathy, aneurysms, and muscle cramps

scientific article

Consensus statement on the immunohistochemical detection of ocular lymphatic vessels

scientific article

DIGE compatible labelling of surface proteins on vital cells in vitro and in vivo

scientific article published in January 2006

Decentral gene expression analysis for ER+/Her2− breast cancer: results of a proficiency testing program for the EndoPredict assay ⬇️

scientific article published on February 28, 2012

Derivation of nephrogenic adenomas from renal tubular cells in kidney-transplant recipients

scientific article

Enhanced podocalyxin expression alters the structure of podocyte basal surface

scientific article

Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy

scientific article published on 20 July 2006

Expression of functional CCR and CXCR chemokine receptors in podocytes

scientific article

Expression of lymphangiogenic factors and evidence of intratumoral lymphangiogenesis in pancreatic endocrine tumors

scientific article

Extrarenal effects on the pathogenesis and relapse of idiopathic nephrotic syndrome in Buffalo/Mna rats

scientific article

Glomerular permeability is altered by loss of P0, a myelin protein expressed in glomerular epithelial cells

scientific article published on 14 September 2005

Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3a

scientific article

HANAC Syndrome Col4a1 Mutation Causes Neonate Glomerular Hyperpermeability and Adult Glomerulocystic Kidney Disease

scientific article published on 10 August 2015

In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye.

scientific article

Inducible nephrin transgene expression in podocytes rescues nephrin-deficient mice from perinatal death

scientific article

Interaction of endogenous nephrin and CD2-associated protein in mouse epithelial M-1 cell line

scientific article

Laser capture microdissection of epithelial cancers guided by antibodies against fibroblast activation protein and endosialin

scientific article

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

scientific article published on 01 March 2018

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

scientific article

Lymphatic exosomes promote dendritic cell migration along guidance cues.

scientific article published on 12 April 2018

Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates

scientific article published in March 2004

Lymphatic neoangiogenesis in renal transplants: a driving force of chronic rejection?

scientific article published on July 2006

Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells

scientific article published on 4 September 2008

Lymphatic spread of ductal pancreatic adenocarcinoma is independent of lymphangiogenesis

scientific article published on November 2005

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

scientific article (publication date: May 2009)

Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis ⬇️

scientific article

Mouse endosialin, a C-type lectin-like cell surface receptor: expression during embryonic development and induction in experimental cancer neoangiogenesis

scientific article

N-wasp is required for stabilization of podocyte foot processes

scientific article published on 7 March 2013

Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

scientific journal article

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release

scientific article

Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease

scientific article published on 08 October 2009

Novel siRNA delivery system to target podocytes in vivo

scientific article (publication date: 2010)

Podocalyxin in human haematopoietic cells

scientific article

Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels

scholarly article

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible

scientific article

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease

scientific article published in August 2007

Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias

scientific article published on December 2011

Radiogenic lymphangiogenesis in the skin

scientific article published in July 2007

Reduction of proteinuria through podocyte alkalinization

scientific article

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

scientific article

Role of the microvascular endothelium in progressive renal disease.

scientific article

Role of the polarity protein Scribble for podocyte differentiation and maintenance

scientific article

Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display

scientific article published on 20 May 2015

Selective binding and presentation of CCL5 by discrete tissue microenvironments during renal inflammation

scientific article published on 09 May 2007

Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin

scientific article

Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells

scientific article

The contribution of B cells to renal interstitial inflammation

scientific article published on February 2007

The human glomerular podocyte is a novel target for insulin action

scientific article published on November 2005

The sialomucin CD34 is a marker of lymphatic endothelial cells in human tumors

scientific article

Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro

scientific article published on January 2007

Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton

scientific article (publication date: April 2006)

Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

scientific article

Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections

scientific article

Vascular endothelial growth factor-C, a potential paracrine regulator of glomerular permeability, increases glomerular endothelial cell monolayer integrity and intracellular calcium

scientific article published on 4 September 2008

Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis

scientific article published on 14 March 2013

When renal allografts turn DARC.

scientific article

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

scientific article

List of works by Dontscho Kerjaschki

2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

A novel protein, densin, expressed by glomerular podocytes

Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury ⬇️

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

COL4A1 mutations and hereditary angiopathy, nephropathy, aneurysms, and muscle cramps

Consensus statement on the immunohistochemical detection of ocular lymphatic vessels

DIGE compatible labelling of surface proteins on vital cells in vitro and in vivo

Decentral gene expression analysis for ER+/Her2− breast cancer: results of a proficiency testing program for the EndoPredict assay ⬇️

Derivation of nephrogenic adenomas from renal tubular cells in kidney-transplant recipients

Enhanced podocalyxin expression alters the structure of podocyte basal surface

Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy

Expression of functional CCR and CXCR chemokine receptors in podocytes

Expression of lymphangiogenic factors and evidence of intratumoral lymphangiogenesis in pancreatic endocrine tumors

Extrarenal effects on the pathogenesis and relapse of idiopathic nephrotic syndrome in Buffalo/Mna rats

Glomerular permeability is altered by loss of P0, a myelin protein expressed in glomerular epithelial cells

Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3a

HANAC Syndrome Col4a1 Mutation Causes Neonate Glomerular Hyperpermeability and Adult Glomerulocystic Kidney Disease

In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye.

Inducible nephrin transgene expression in podocytes rescues nephrin-deficient mice from perinatal death

Interaction of endogenous nephrin and CD2-associated protein in mouse epithelial M-1 cell line

Laser capture microdissection of epithelial cancers guided by antibodies against fibroblast activation protein and endosialin

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

Lymphatic exosomes promote dendritic cell migration along guidance cues.

Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates

Lymphatic neoangiogenesis in renal transplants: a driving force of chronic rejection?

Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells

Lymphatic spread of ductal pancreatic adenocarcinoma is independent of lymphangiogenesis

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis ⬇️

Mouse endosialin, a C-type lectin-like cell surface receptor: expression during embryonic development and induction in experimental cancer neoangiogenesis

N-wasp is required for stabilization of podocyte foot processes

Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release

Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease

Novel siRNA delivery system to target podocytes in vivo

Podocalyxin in human haematopoietic cells

Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease

Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias

Radiogenic lymphangiogenesis in the skin

Reduction of proteinuria through podocyte alkalinization

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

Role of the microvascular endothelium in progressive renal disease.

Role of the polarity protein Scribble for podocyte differentiation and maintenance

Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display

Selective binding and presentation of CCL5 by discrete tissue microenvironments during renal inflammation

Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin

Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells

The contribution of B cells to renal interstitial inflammation

The human glomerular podocyte is a novel target for insulin action

The sialomucin CD34 is a marker of lymphatic endothelial cells in human tumors

Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro

Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton

Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections

Vascular endothelial growth factor-C, a potential paracrine regulator of glomerular permeability, increases glomerular endothelial cell monolayer integrity and intracellular calcium

Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis

When renal allografts turn DARC.

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress