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List of works by Veli-Matti Leppänen

CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation

scientific article

Characterization of ANGPT2 mutations associated with primary lymphedema

scientific article published on 01 September 2020

Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization

scientific article published on 26 June 2013

Crystal structure of the N-terminal NC4 domain of collagen IX, a zinc binding member of the laminin-neurexin-sex hormone binding globulin (LNS) domain family

scientific article

Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization

scientific article

Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1

scientific article

Endothelial destabilization by angiopoietin-2 via integrin β1 activation.

scientific article

Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain.

scientific article

Genetic variants of VEGFA and FLT4 are determinants of survival in renal cell carcinoma patients treated with sorafenib

scientific article published on 01 November 2018

High baseline Tie1 level predicts poor survival in metastatic breast cancer

scientific article published on 24 July 2019

Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts.

scientific article

Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

scientific article published in 2022

Purification of Major Lignin Peroxidase Isoenzymes from Phanerochaete chrysosporium by Chromatofocusing ⬇️

scientific article published on 01 June 1995

Receptor tyrosine kinase-mediated angiogenesis

scientific article

SnapShot: Angiopoietins and Their Functions.

scientific article

Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation

scientific article

Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization.

scientific article

Structural determinants of growth factor binding and specificity by VEGF receptor 2

scientific article

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

scientific article

Structure of Escherichia coli pyruvate formate-lyase with pyruvate

scientific article

The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel

scientific article (publication date: September 2014)

The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands.

scientific article published on 2 July 2013

The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional

scientific article

Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization

scientific article

Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells

scientific article published on 28 August 2018

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

scientific article

Vascular endothelial growth factor signaling in development and disease

scientific article published on 20 July 2018

Vascular endothelial growth factor-B in physiology and disease

scientific article

Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis

scientific article published on January 2013

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