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List of works by Nevan Krogan

A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.

scientific article

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells

scientific article published on October 2016

A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S

scientific article

A Quantitative Genetic Interaction Map of HIV Infection

scientific article published on 17 February 2020

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing ⬇️

journal article from 'bioRxiv' published in 2020

A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

scientific article

A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability

scientific article (publication date: 2014)

A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay

scientific journal article

A complex-based reconstruction of the Saccharomyces cerevisiae interactome

scientific article

A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.

scientific article

A functional map of HIV-host interactions in primary human T cells

scientific article published on 01 April 2022

A gene ontology inferred from molecular networks

scientific article published on January 2013

A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing

scientific article

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.

scientific article

A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator

scientific article

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

scientific article

A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress

scientific article published on 25 July 2013

A panoramic view of yeast noncoding RNA processing

scientific article

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

scientific article

A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking

scientific article

A protein interaction landscape of breast cancer

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity

A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa

scientific article published on 3 May 2016

A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast

scientific article

A strategy for extracting and analyzing large-scale quantitative epistatic interaction data

scientific article

A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.

scientific article

A systems approach to infectious disease

scientific article published on 14 February 2020

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection

scientific article published on 25 June 2019

Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1.

scientific article published on 7 November 2014

Adventures in time and space: splicing efficiency and RNA polymerase II elongation rate

scientific article

All or nothing: protein complexes flip essentiality between distantly related eukaryotes.

scientific article

An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells

scientific article published on April 2017

An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses

scientific article published on 01 August 2018

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

scientific article published on 15 November 2009

An atlas of chaperone-protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell

scientific article

An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics

scientific article

An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation

scientific article published on 10 August 2020

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

scientific article published on 05 November 2020

Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription

scientific article published on 29 August 2019

Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p

scientific article

Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

scientific article

BAC to the future: functional genomics in mammals

scientific article published in May 2008

BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex

scientific article

Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss

scientific article published on 27 March 2007

Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter

scientific article

Bringing it all together: big data and HIV research

scientific article

Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2

scientific article

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.

scientific article published on 17 January 2013

CCR4/NOT complex associates with the proteasome and regulates histone methylation

scholarly article

CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing

scientific article

COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression

scientific article

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

scientific article

CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions

scientific article published on 01 January 2019

CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells

scientific article published in 2024

CRL4 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling

scientific article published on 30 August 2018

Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109.

scientific article

Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress

scientific article published on 17 May 2019

Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.

scientific article

Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction.

scientific article published on 02 March 2017

Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment

scientific article

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

scientific article

Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome.

scientific article

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

scientific article published on 01 December 2018

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

scientific article published on 15 October 2020

Comparative interaction networks: bridging genotype to phenotype.

scientific article published on January 2012

Comparative mapping of host-pathogen protein-protein interactions

scientific article

Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae

scientific article

Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.

scientific article published on 25 September 2008

Correction: A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S

scientific article published on 21 July 2017

Correction: Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species.

scientific article published on 25 November 2009

Correction: Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 S particle

scientific article published on 01 July 2020

Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex

scientific article

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

scientific article

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action

scientific article

Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins

scientific article published on 01 May 2019

Crosstalk signaling between HER3 and HPV16 E6 and E7 mediates resistance to PI3K inhibitors in head and neck cancer

scientific article published on 12 February 2018

Cullin E3 ligases and their rewiring by viral factors

scientific article

Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts

scientific article

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core

scientific article published on 01 March 2020

DNA Preparation from Schizosaccharomyces pombe

scientific article published on 21 July 2017

Differential genetic interactions of yeast stress response MAPK pathways

scientific article published on 17 April 2015

Differential network biology

scientific article published on 17 January 2012

Discovery and functional characterization of a neomorphic PTEN mutation.

scientific article

Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.

scientific article published on 11 January 2013

Dissection of DNA damage responses using multiconditional genetic interaction maps

scientific article

Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs

scientific article

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2

scientific article

Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis

scientific article published on 05 July 2019

Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages

scientific article published on 17 January 2020

ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae

scientific article

Eisosome proteins assemble into a membrane scaffold

scientific article

Endosomal cAMP production broadly impacts the cellular phosphoproteome

scientific article

Ensemble non-negative matrix factorization methods for clustering protein-protein interactions.

scientific article published on 12 June 2008

Enterovirus pathogenesis requires the host methyltransferase SETD3

scientific article published on 16 September 2019

Envelope protein ubiquitination drives entry and pathogenesis of Zika virus

scientific article published on 08 July 2020

EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion

scientific article published in Scientific Reports

Epistatic relationships reveal the functional organization of yeast transcription factors

scientific article

Erratum: Corrigendum: A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery

scientific article published in Nature

Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5' end sequences complementary to domain # 17 on the 16S ribosomal RNA.

scientific article published in April 2004

Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction

scientific article

Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

scientific article published on 27 August 2020

Evolution and functional cross-talk of protein post-translational modifications

scientific article

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

scientific article

Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species

scientific article

Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells

scientific article

Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways

scientific article published in December 2017

Exploration of essential gene functions via titratable promoter alleles

scientific article

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

scientific article

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors

scientific article published on 5 January 2018

First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G

scientific article

From information to knowledge: new technologies for defining gene function

scientific article published on October 2009

From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.

scientific article published on 8 August 2013

From systems to structure: bridging networks and mechanism

scientific article

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

scientific article (publication date: 12 April 2007)

Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

scientific article published on 24 September 2020

Functional genomics of the yeast DNA-damage response

scientific article published on January 2006

Functional maps of protein complexes from quantitative genetic interaction data

scientific article

Functional organization of the S. cerevisiae phosphorylation network

scientific article

Functional overlap and regulatory links shape genetic interactions between signaling pathways.

scientific article published in December 2010

Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase

scientific article

G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands

scientific article

GPS-Prot: A web-based visualization platform for integrating host-pathogen interaction data ⬇️

scientific article published on July 22, 2011

GammaH2AX and its role in DNA double-strand break repair

scientific article published on August 2006

Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants

scientific article published on 19 March 2015

Genetic Interaction Mapping in Schizosaccharomyces pombe Using the Pombe Epistasis Mapper (PEM) System and a ROTOR HDA Colony Replicating Robot in a 1536 Array Format.

scientific article published on 21 July 2017

Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast

scientific article

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses

scientific article published on 9 December 2020

Genetic analysis reveals functions of atypical polyubiquitin chains

scientific article published on 14 December 2018

Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations

scientific article published on 20 May 2014

Genetic interaction mapping in mammalian cells using CRISPR interference

scientific article published on 8 May 2017

Genetic interaction mapping informs integrative structure determination of protein complexes

scientific article published on 01 December 2020

Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast

scientific article

Genome-wide association data reveal a global map of genetic interactions among protein complexes

scientific article

Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection

scientific article published on 25 June 2015

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

scientific article published on 09 June 2013

Global landscape of HIV-human protein complexes

scientific article

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

scientific article

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes

scientific article

Global mapping of the yeast genetic interaction network

scientific article

H2B Ubiquitylation Acts as a Barrier to Ctk1 Nucleosomal Recruitment Prior to Removal by Ubp8 within a SAGA-Related Complex

scientific article published in July 2007

H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex.

scientific article

HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells

scientific article published on January 2010

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

scientific article

Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.

scientific article

Hierarchical modularity and the evolution of genetic interactomes across species.

scientific article

High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe.

scientific article

High-definition macromolecular composition of yeast RNA-processing complexes

scientific article

High-resolution network biology: connecting sequence with function

scientific article

High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8.

scientific article

High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe

scientific article

High-throughput, quantitative analyses of genetic interactions in E. coli

scientific article

Histone H2B ubiquitylation is associated with elongating RNA polymerase II

scientific article

Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production ⬇️

scientific article published on December 15, 2011

Host cell factors in HIV replication: meta-analysis of genome-wide studies

scientific article

How many human proteoforms are there?

scientific article published in February 2018

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

scientific article published on 17 June 2020

IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

scientific article

INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

scientific article

Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae

scientific article

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function

scientific article published on 22 February 2014

Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection

scientific article published on 04 March 2019

Improved functional overview of protein complexes using inferred epistatic relationships.

scientific article

Imputing and predicting quantitative genetic interactions in epistatic MAPs.

scientific article published on January 2011

Individual Lysine Acetylations on the N Terminus of Saccharomyces cerevisiae H2A.Z Are Highly but Not Differentially Regulated ⬇️

scientific article published on October 14, 2010

Influenza virus infection causes global RNAPII termination defects

Inhibition of CRISPR-Cas9 with Bacteriophage Proteins

scientific article

Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models

scientific article

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

scientific article

Interaction network containing conserved and essential protein complexes in Escherichia coli

scientific article (publication date: 3 February 2005)

Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator

scientific article published on 24 November 2004

Interpretation of cancer mutations using a multiscale map of protein systems

scientific article published on 01 October 2021

Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs

scientific article published on February 2007

Key functional regions in the histone variant H2A.Z C-terminal docking domain

scientific article published on 26 July 2011

Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells

scientific article published on 29 July 2019

Learning a prior on regulatory potential from eQTL data

scientific article

Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity

scientific article

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

scientific article published on 12 December 2014

Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing.

scientific article

Mapping genetic interactions in cancer: a road to rational combination therapies

scientific article published on 22 October 2019

Mapping the protein-protein and genetic interactions of cancer to guide precision medicine

scientific article published on 01 February 2019

Mass spectrometry-based protein-protein interaction networks for the study of human diseases

publication published on 01 January 2021

Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses

scientific article

Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

scientific article

Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1.

scientific article published on 30 November 2017

Moloney leukemia virus type 10 inhibits reverse transcription and retrotransposition of intracisternal a particles

scientific article published on 18 July 2012

Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network

scientific article published on 12 September 2018

Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly

scientific article published on 14 November 2019

Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects

scientific article

Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease

scientific article published on 30 August 2018

NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer

scientific article

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

scientific article

Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function

scientific article published on 01 January 2019

Non-degradative Ubiquitination of Protein Kinases.

scientific article

Nonsense-mediated decay regulates key components of homologous recombination

scientific article published on 21 March 2016

Optimal stepwise experimental design for pairwise functional interaction studies

scientific article published on 18 September 2008

PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization

scientific article published on 16 July 2019

PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs

scientific article

PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription

scientific article published on 27 March 2017

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

scientific article published on 15 April 2015

Phenotypic landscape of a bacterial cell

scientific article

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

scientific journal article

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal

scientific journal article

Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1.

scientific article published on 17 July 2015

Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes.

scientific article

Proteasome Involvement in the Repair of DNA Double-Strand Breaks

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication

scientific article published on 01 December 2018

Protein Moonlighting Revealed by Non-catalytic Phenotypes of Yeast Enzymes

scientific article

Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits.

scientific article

Purification and characterization of HIV-human protein complexes

scientific article

Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection

scientific article published on 01 August 2018

Quantitative analysis of triple-mutant genetic interactions

scientific article

Quantitative genetic interaction mapping using the E-MAP approach

scientific article published on March 2010

Quantitative genetic interactions reveal biological modularity

scientific article published on May 2010

Quantitative genetic-interaction mapping in mammalian cells

scientific article published on 13 February 2013

RNA polymerase II carboxyl-terminal domain phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36

scientific article published on 7 December 2011

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

scientific article

Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast

scientific article published on 10 September 2019

Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling

scientific article

Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4

scientific article

Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant

scientific article published on 27 August 2012

Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy

scientific article published on 23 September 2021

Rewiring of genetic networks in response to DNA damage.

scientific article

SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells

scientific article published on 19 August 2020

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

scientific article published on 10 November 2020

SIN-fully silent: HDAC complexes in fission yeast

scientific article

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.

scientific article

SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1

scientific article published on 17 April 2019

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

scientific article published in February 2018

SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency

scientific article published on May 2017

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors ⬇️

scientific article published on May 22, 2011

Scoring Large-Scale Affinity Purification Mass Spectrometry Datasets with MiST.

scientific article published on 9 March 2015

Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons

scientific article published on 17 January 2014

Signals and systems

scientific article published on 25 April 2006

Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress

scientific article

Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining

scientific article published on 11 May 2015

Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant

scientific article published on 28 December 2019

Structural basis of CD4 downregulation by HIV-1 Nef

scientific article published on 27 July 2020

Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106.

scientific article published on 10 January 2017

Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis

scientific article published in Scientific Reports

Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

scientific article published on 01 August 2019

Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen

scientific article published on 17 September 2019

Systematic characterization of the protein interaction network and protein complexes in Saccharomyces cerevisiae using tandem affinity purification and mass spectrometry

scientific article

Systematic functional prioritization of protein posttranslational modifications

scientific article

Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation.

scientific article published on 06 June 2013

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells

scientific article

Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.

scientific article

Systems-level analyses identify extensive coupling among gene expression machines

scientific article published on 17 January 2006

Systems-level effects of allosteric perturbations to a model molecular switch

scientific article published on 13 October 2021

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

scientific article published on January 2016

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

article

Test performance evaluation of SARS-CoV-2 serological assays

scientific article published on 29 April 2020

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat

scientific article

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

scholarly article by Krystal A Fontaine et al published 6 November 2018 in mBio

The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

scientific article (publication date: August 2016)

The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription

scientific article published on 01 September 2020

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

scientific article published on 10 March 2022

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

scientific article published on 28 June 2020

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells

scientific article published on 22 March 2018

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

scientific article

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication

scientific article

The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2

scientific article published on 22 May 2020

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation

scientific article

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders

article by A Jeremy Willsey et al published 26 July 2018 in Cell

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity

scientific article published on May 2017

The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes.

scientific article published on 6 November 2006

The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4.

scientific article

The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism

scientific article

The Tyrosine Kinase Inhibitor Gefitinib Restricts Mycobacterium tuberculosis Growth through Increased Lysosomal Biogenesis and Modulation of Cytokine Signaling.

scientific article

The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1

scientific article published on 10 December 2018

The cancer cell map initiative: defining the hallmark networks of cancer

scientific article published on May 2015

The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion

scientific article

The functional landscape of mouse gene expression

scientific article

The functional landscape of the human phosphoproteome

scientific article published on 09 December 2019

The histone variant H2A.Z promotes splicing of weak introns.

scientific article published on April 2017

The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae

scientific article published on 24 June 2020

The mTOR Complex Controls HIV Latency ⬇️

scientific article

The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

scientific article published on 25 November 2004

The yeast SR-like protein Npl3 links chromatin modification to mRNA processing

scientific article

Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.

scientific article published on 06 April 2009

Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae

scientific article (publication date: March 2007)

Towards accurate imputation of quantitative genetic interactions

scientific article published on 10 December 2009

Transformation of Schizosaccharomyces pombe in a 96-Well Format.

scientific article published on 21 July 2017

Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems

scientific article published on February 2016

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria

scientific article published on 25 June 2019

Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast

scientific article

Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells

scientific article published on 22 May 2020

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection ⬇️

scientific article published on December 21, 2011

Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets

scientific article published on 11 December 2018

Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

scientific article

Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts

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Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function

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mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1

scientific article published on 15 May 2020

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