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List of works by Herbert W. Virgin

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

scientific article

A 'fly-by' killing with a primordial cellular weapon

scientific article published in August 2008

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

scientific article

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

scientific article published on 23 May 2019

A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease

scientific article published on 8 February 2009

A gamma-herpesvirus deficient in replication establishes chronic infection in vivo and is impervious to restriction by adaptive immune cells

scientific article published on 21 June 2006

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

scientific article published in 2021

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

scientific article (publication date: 13 November 2008)

A perspective on potential antibody-dependent enhancement of SARS-CoV-2

scientific article published on 13 July 2020

A severe combined immunodeficient (SCID) mouse model for infection with Entamoeba histolytica ⬇️

scientific article published on December 1, 1992

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence

scientific article published on 17 October 2012

A surface groove essential for viral Bcl-2 function during chronic infection in vivo

scientific article

ATG5 regulates plasma cell differentiation

scientific article published on 17 January 2013

Accounting for reciprocal host-microbiome interactions in experimental science

scientific article

Adaptive immunity restricts replication of novel murine astroviruses

scientific article

Advances in Genomics for Drug Development

scientific article published on 15 August 2020

Advances in norovirus biology

scientific article

After the pandemic: perspectives on the future trajectory of COVID-19

scientific article published in 2021

Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency

scientific article published on November 2005

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

scientific article

An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection

scientific article

An optimized CD8+ T-cell response controls productive and latent gammaherpesvirus infection

scientific article published on February 2005

Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system

scientific article

Antibody is critical for the clearance of murine norovirus infection

scientific article published on 16 April 2008

Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing)

scientific article

Antibody to a lytic cycle viral protein decreases gammaherpesvirus latency in B-cell-deficient mice

scientific article published on November 2002

Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses

scientific article published on 23 June 2006

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

scientific article

Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo

scientific article

Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection

scientific article published on 21 August 2013

Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens

scientific article

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

scientific article

Autophagy genes in immunity

scientific article published on May 2009

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock

scientific article published on 25 July 2019

Autophagy in immunity and inflammation

scientific article

Autophagy is essential for effector CD8(+) T cell survival and memory formation

scientific article

Autophagy links inflammasomes to atherosclerotic progression.

scientific article published on 20 March 2012

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

scientific journal article

Autophagy proteins regulate the secretory component of osteoclastic bone resorption

scientific article published on 4 November 2011

Beth Cindy Levine (1960-2020)

scientific article published on 01 July 2020

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

scientific article published on 12 September 2019

Brain- and intestine-specific variants of reovirus serotype 3 strain dearing are selected during chronic infection of severe combined immunodeficient mice

scientific article published in June 1995

Broad betacoronavirus neutralization by a stem helix–specific human antibody

scientific article

Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

scientific article

CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNgamma

scientific article published on 01 August 2005

Cellular and Humoral Immunity to Reovirus Infection ⬇️

scientific article published on 01 January 1998

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

scientific article published on May 2015

Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency

scientific article

Characterization of gammaherpesvirus 68 gene 50 transcription

scientific article

Circulating immunoglobulin G can play a critical role in clearance of intestinal reovirus infection.

scientific article published in February 1996

Cleavage map and proteolytic processing of the murine norovirus nonstructural polyprotein in infected cells

scientific article

Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival

scientific article published on 18 March 2016

Clinical genomicist workstation

scientific article published on 18 March 2013

Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

scientific article

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

scientific article

Complete sequence and genomic analysis of murine gammaherpesvirus 68 ⬇️

scientific article published on August 1, 1997

Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors

scientific article

Coronavirus replication does not require the autophagy gene ATG5

scientific article published on 24 July 2007

Correction: Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

scientific article published on 21 March 2016

Correction: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

Correction: MDA-5 Recognition of a Murine Norovirus.

scientific article published on 10 October 2008

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

scientific article published on 17 February 2017

Corrigendum: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

scientific article published on 28 September 2016

Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

scientific article published on 8 July 2015

Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis

scientific article

Critical role for interferon regulatory factor 3 (IRF-3) and IRF-7 in type I interferon-mediated control of murine norovirus replication

scientific article

Critical role of CD4 T cells in an antibody-independent mechanism of vaccination against gammaherpesvirus latency

scientific article

Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection

scientific article published on August 2002

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

scientific article published on 18 May 2020

Cytidine monophosphate N-acetylneuraminic acid synthetase and solute carrier family 35 member A1 are required for reovirus binding and infection

scientific article published on 21 October 2020

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway

scientific article published on 6 August 2012

Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties.

scientific article

Detection of novel sequences related to african Swine Fever virus in human serum and sewage

scientific article published on 07 October 2009

Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche

scientific article published on 10 October 2017

Discovery of a proteinaceous cellular receptor for a norovirus

scientific article

Disease-specific alterations in the enteric virome in inflammatory bowel disease

scientific article

Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier

scientific article published on 24 October 2004

Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication

scientific article

Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation

scientific article

Disruption of the gene encoding the gammaHV68 v-GPCR leads to decreased efficiency of reactivation from latency

scientific article published in March 2003

Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency

scientific article

Drowning in Viruses

scientific article published on 01 May 2019

Early B-Cell Activation after West Nile Virus Infection Requires Alpha/Beta Interferon but Not Antigen Receptor Signaling

scientific article

Effective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells

scientific article published on 19 May 2006

Effective vaccination against long-term gammaherpesvirus latency

scientific article

Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

scientific article published on February 2016

Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.

scientific article published on 29 February 2016

Erratum: Corrigendum: Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

scientific article published in November 2013

Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages

scientific article

Establishment and maintenance of gammaherpesvirus latency are independent of infective dose and route of infection

scientific article

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

scientific article

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus

scientific article published on 11 January 2017

FIP200 regulates targeting of Atg16L1 to the isolation membrane

scientific article

Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection

scientific article published on 08 October 2020

Gamma interferon blocks gammaherpesvirus reactivation from latency

scientific article

Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner

scientific article published on 14 March 2007

Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication

scientific article

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

scientific article

Genetic mapping of reovirus virulence and organ tropism in severe combined immunodeficient mice: organ-specific virulence genes.

scientific article published in January 1995

Granzymes and caspase 3 play important roles in control of gammaherpesvirus latency

scientific article

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii

scientific article

Gut DNA viromes of Malawian twins discordant for severe acute malnutrition

scientific article

HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection

scholarly article by Donna A MacDuff et al published 1 December 2018 in Journal of Virology

Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter

scientific article

Herpesvirus latency and symbiotic protection from bacterial infection

scientific article published on February 2009

Herpesvirus latency confers symbiotic protection from bacterial infection

scientific article

High Throughput Screen Identifies Interferon γ-Dependent Inhibitors of Toxoplasma gondii Growth

scientific article published on 28 August 2018

High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains

scientific article

Histone deacetylases and the nuclear receptor corepressor regulate lytic-latent switch gene 50 in murine gammaherpesvirus 68-infected macrophages

scientific article

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis

scientific article

Host and viral genes that control herpesvirus vasculitis.

scientific article

Host and viral genetics of chronic infection: a mouse model of gamma-herpesvirus pathogenesis

scientific article

IFN-gamma action in the media of the great elastic arteries, a novel immunoprivileged site

scientific article

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

scientific journal article

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

scientific article

Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein

scientific article published on May 1999

Identification and sequencing of a novel rodent gammaherpesvirus that establishes acute and latent infection in laboratory mice

scientific article published on 5 January 2011

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

scientific article published on 10 July 2009

Identification of a candidate therapeutic autophagy-inducing peptide

scientific journal article

Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action

scientific article

Identification of a novel astrovirus (astrovirus VA1) associated with an outbreak of acute gastroenteritis

scientific article published on 12 August 2009

Identification of alternative transcripts encoding the essential murine gammaherpesvirus lytic transactivator RTA

scientific article

Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo

scientific article

Identification of novel microRNA-like molecules generated from herpesvirus and host tRNA transcripts

scientific article

Identification of novel viruses using VirusHunter--an automated data analysis pipeline

scientific article

Identification of the in vivo role of a viral bcl-2

scientific article

Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus

scientific article published on July 2002

Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection

scientific article

Immune regulation of viral infection and vice versa

scientific article

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

scientific article

Immunology and the elusive AIDS vaccine

scientific article published in Nature

Impaired autophagy in macrophages promotes inflammatory eye disease

scientific article published on 27 July 2016

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

scientific article published on 11 November 2022

Innate immune receptor NOD2 mediates LGR5+ intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation

scientific article published on 09 January 2020

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

scientific article published on 26 November 2020

Interferon gamma regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels

scientific article

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

scientific article

Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation ⬇️

scientific article

Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity

scientific article

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

scientific article published on 10 July 2017

Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation

scientific article published on 29 April 2015

Kingdom-agnostic metagenomics and the importance of complete characterization of enteric microbial communities

scientific article

Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

scientific article published on 9 January 2017

Late expression of a beta chemokine homolog by murine cytomegalovirus.

scientific article published in February 1997

Latent gammaherpesvirus 68 infection induces distinct transcriptional changes in different organs

scientific article (publication date: 2014)

Latent herpesvirus infection arms NK cells

scientific article

Latent murine cytomegalovirus infection in macrophages

scientific article published on 01 January 1997

Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

scientific article

Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection

scientific article

Lymphocytes protect against and are not required for reovirus-induced myocarditis.

scientific article published on October 1993

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.

scientific article published in March 2018

MDA-5 recognition of a murine norovirus

scientific article published in July 2008

MHC II+ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes

scientific article published on 22 August 2016

MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner

scientific article

Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells

scientific article published on April 1999

Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes

scientific article

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

scientific article published on 16 September 2020

Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68.

scientific article

Metagenomics and personalized medicine

scientific article

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

scientific article

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action ⬇️

scientific article published on December 1, 1991

Mouse norovirus replication is associated with virus-induced vesicle clusters originating from membranes derived from the secretory pathway

scientific article published on 08 July 2009

Mucosal and Parenteral Vaccination against Acute and Latent Murine Cytomegalovirus (MCMV) Infection by Using an Attenuated MCMV Mutant ⬇️

scientific article published on January 1, 1998

Murine cytomegalovirus infection inhibits IFN gamma-induced MHC class II expression on macrophages: the role of type I interferon

scientific article published on 01 February 1998

Murine cytomegalovirus infection inhibits tumor necrosis factor alpha responses in primary macrophages

scientific article

Murine cytomegalovirus inhibits interferon gamma-induced antigen presentation to CD4 T cells by macrophages via regulation of expression of major histocompatibility complex class II-associated genes

scientific article

Murine cytomegalovirus paralyzes macrophages by blocking IFN gamma-induced promoter assembly

scientific article

Murine cytomegalovirus with a deletion of genes spanning HindIII-J and -I displays altered cell and tissue tropism

scientific article published in March 1996

Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease.

scientific article published in December 1997

Murine gammaherpesvirus 68 encodes a functional regulator of complement activation

scientific article

Murine gammaherpesvirus 68 genes both induce and suppress lymphoproliferative disease

scientific article

Murine gammaherpesvirus 68 has evolved gamma interferon and stat1-repressible promoters for the lytic switch gene 50.

scientific article

Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice

scientific article

Murine norovirus infection has no significant effect on adaptive immunity to vaccinia virus or influenza A virus

scientific article published on 29 April 2009

Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain

scientific article

Murine norovirus: a model system to study norovirus biology and pathogenesis

scientific article

Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence

scientific article

Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection

scientific article published on 17 June 2013

Natural killer cells utilize both perforin and gamma interferon to regulate murine cytomegalovirus infection in the spleen and liver

scientific article

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

scientific article published on 27 May 2020

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

scientific article published on 03 July 2020

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2

scientific article published on 19 May 2020

Newly discovered viral E3 ligase pK3 induces endoplasmic reticulum-associated degradation of class I major histocompatibility proteins and their membrane-bound chaperones

scientific article published on 8 March 2012

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma

scientific article

Norovirus Cell Tropism Is Determined by Combinatorial Action of a Viral Non-structural Protein and Host Cytokine.

scientific article published on 27 September 2017

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.

scientific article published on 11 July 2017

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

scientific article

Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage

scientific article

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

scientific article published on 18 January 2016

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

scientific article published in March 2018

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

scientific article

PKR-dependent autophagic degradation of herpes simplex virus type 1.

scientific article published on 15 January 2006

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

scientific article

Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome

scientific article

Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses

scientific article published on 17 April 2013

Pervasive transcription of a herpesvirus genome generates functionally important RNAs

scientific article published on 11 March 2014

Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection

scientific article

Physical association of the K3 protein of gamma-2 herpesvirus 68 with major histocompatibility complex class I molecules with impaired peptide and beta(2)-microglobulin assembly

scientific article published on March 2002

Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis

scientific article published on June 1993

Protective antibodies inhibit reovirus internalization and uncoating by intracellular proteases.

scientific article published on October 1994

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

scientific article

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells

scientific article

Protruding domain of capsid protein is necessary and sufficient to determine murine norovirus replication and pathogenesis in vivo

scientific article published on 18 January 2012

Quaranfil, Johnston Atoll, and Lake Chad Viruses Are Novel Members of the Family Orthomyxoviridae

scientific article

RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

retracted scholarly article

Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors

scientific article published on 3 January 2018

Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNA.

scholarly article

Redefining chronic viral infection

scientific article

Redefining the genetics of murine gammaherpesvirus 68 via transcriptome-based annotation

scientific article published on June 2010

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

scientific article

Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages

scientific article

Replication of murine cytomegalovirus in differentiated macrophages as a determinant of viral pathogenesis

scientific article published on July 1999

Reservoir host immune responses to emerging zoonotic viruses

scientific article

Role of autophagy and autophagy genes in inflammatory bowel disease

scientific article published on January 2009

Role of immune cells in protection against and control of reovirus infection in neonatal mice

scientific article published on October 1991

SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern

scientific article

SIV Infection-Mediated Changes in Gastrointestinal Bacterial Microbiome and Virome Are Associated with Immunodeficiency and Prevented by Vaccination

scientific article

STAT1-dependent innate immunity to a Norwalk-like virus

scientific article

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

scientific article published on 20 January 2020

Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle

scientific article published on January 2012

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

scientific article

Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response

scientific article published on 18 April 2016

Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus

scientific article

Solution structure of the BHRF1 protein from Epstein-Barr virus, a homolog of human Bcl-2

scientific article

Specific mutation of a gammaherpesvirus-expressed antigen in response to CD8 T cell selection in vivo

scientific article

Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection

scholarly article by Robert C Orchard et al published October 2018 in Nature Microbiology

Spliced mRNA encoding the murine cytomegalovirus chemokine homolog predicts a beta chemokine of novel structure

scientific article

Structural and functional analysis of a potent sarbecovirus neutralizing antibody

scientific article published on 09 April 2020

Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural basis of chemokine sequestration by a herpesvirus decoy receptor

scientific article

Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles

scientific article

TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41

scientific article published on 01 November 2020

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

scientific article published on August 2017

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

scientific article published on 2 June 2015

The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.

scientific article

The Murine Gammaherpesvirus 68 v-Cyclin Gene Is an Oncogene That Promotes Cell Cycle Progression in Primary Lymphocytes

The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections.

scientific article published on February 1995

The autophagy gene ATG5 plays an essential role in B lymphocyte development

scientific article published on 24 December 2007

The genome of Yoka poxvirus

scientific article

The interferon-inducible gene viperin restricts West Nile virus pathogenesis

scientific journal article

The murine gammaherpesvirus 68 v-cyclin gene is an oncogene that promotes cell cycle progression in primary lymphocytes

scientific article

The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency.

scientific article published on August 2000

The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.

scientific article

The virome in mammalian physiology and disease

scientific article (publication date: 27 March 2014)

Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice

scientific article

Tropism for tuft cells determines immune promotion of norovirus pathogenesis.

scientific article

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

scientific article

Type I interferons link viral infection to enhanced epithelial turnover and repair.

scientific article

UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages

scientific article published on 01 January 2021

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

scientific article

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

scientific article published on 9 December 2015

Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection

scientific article

Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation

scientific article

Validation of a next-generation sequencing assay for clinical molecular oncology.

scientific article published on 6 November 2013

Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation

scientific article published on 16 February 2015

Viral chemokine-binding proteins inhibit inflammatory responses and aortic allograft transplant vasculopathy in rat models

scientific article published in June 2004

Viral immunity. Transkingdom control of viral infection and immunity in the mammalian intestine

scientific article

Virome biogeography in the lower gastrointestinal tract of rhesus macaques with chronic diarrhea

scientific article published on 20 November 2018

Virus subversion of the MHC class I peptide-loading complex

scientific article published on January 2003

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

scientific article

VirusSeeker, a computational pipeline for virus discovery and virome composition analysis

scientific article (publication date: March 2017)

WDFY4 is required for cross-presentation in response to viral and tumor antigens

scientific article

“Next-Generation” Pathology and Laboratory Medicine

scholarly article by David N Louis et al published December 2011 in Archives of Pathology & Laboratory Medicine

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