Search filters

List of works by Andreas Rosenwald

2-D PAGE-based comparison of proteasome inhibitor bortezomib in sensitive and resistant mantle cell lymphoma

scientific article

A 70% cut-off for MYC protein expression in diffuse large B cell lymphoma identifies a high-risk group of patients

scientific article published on 13 February 2020

A GRP78-Directed Monoclonal Antibody Recaptures Response in Refractory Multiple Myeloma with Extramedullary Involvement

scientific article published on 30 March 2016

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling

scientific article published in June 2006

A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy

scientific article published on 07 March 2019

A cytomorphological and immunohistochemical profile of aggressive B-cell lymphoma: high clinical impact of a cumulative immunohistochemical outcome predictor score

scientific article

A distinctive subtype of t(14;18)-negative nodal follicular non-Hodgkin lymphoma characterized by a predominantly diffuse growth pattern and deletions in the chromosomal region 1p36

scientific article published on 31 October 2008

A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

scientific article

A gene signature that distinguishes conventional and leukemic nonnodal mantle cell lymphoma helps predict outcome

article

A modular transcriptome map of mature B cell lymphomas

article

A multiplex MALDI-TOF MS approach facilitates genotyping of DNA from formalin-fixed paraffin-embedded tumour specimens

scientific article published on October 1, 2010

A multiprotein supercomplex controlling oncogenic signalling in lymphoma

scientific article published in Nature

A new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma

scientific article

A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy

scientific article

A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL

scientific article published on 17 September 2019

ALK-positive anaplastic large-cell lymphoma in adults: an individual patient data pooled analysis of 263 patients

scientific article published on 19 April 2019

ATM activity in T cells is critical for immune surveillance of lymphoma in vivo

scientific article published on 05 November 2019

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma

scientific article

Accurate classification of diffuse large B-cell lymphoma into germinal center and activated B-cell subtypes using a nuclease protection assay on formalin-fixed, paraffin-embedded tissues

scientific article

Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP

scientific article

Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets

scientific article

Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC.

scientific article published on 25 August 2017

Aggressive genomic features in clinically indolent primary HHV8-negative effusion-based lymphoma

scientific article published on 03 December 2018

Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial

scientific article published on 07 May 2020

Allele-specific PCR is a powerful tool for the detection of the MYD88 L265P mutation in diffuse large B cell lymphoma and decalcified bone marrow samples

scientific article published on 30 March 2015

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

scientific article

Alternative BRAF mutations in BRAF V600E-negative hairy cell leukaemias

scientific article published on 16 January 2014

Amplification at 11q23 targets protein kinase SIK2 in diffuse large B-cell lymphoma

scientific article published on May 2010

An analysis of the role of follicular lymphoma-associated fibroblasts to promote tumor cell viability following drug-induced apoptosis

scientific article published on 6 December 2016

Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling

scientific article published on 14 November 2002

Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas

scientific article published on 24 April 2008

Analysis of the tumor microenvironment by whole-slide image analysis identifies low B cell content as a predictor of adverse outcome in advanced-stage classical Hodgkin lymphoma treated with BEACOPP

scientific article published on 07 May 2020

Anaplastic large cell lymphomas lack the expression of T-cell receptor molecules or molecules of proximal T-cell receptor signaling

scientific article published on 05 August 2004

Anti-Apoptotic Signature in Thymic Squamous Cell Carcinomas - Functional Relevance of Anti-Apoptotic BIRC3 Expression in the Thymic Carcinoma Cell Line 1889c

scientific article published on 31 December 2013

Application of MALDI imaging for the diagnosis of classical Hodgkin lymphoma

scientific article published on February 21, 2010

Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells

scientific article

Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

B-cell lymphomas with discordance between pathological features and clinical behavior

scientific article published in June 2017

B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma.

scientific article published on 18 November 2016

BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

scientific article

BCL2 antibodies targeted at different epitopes detect varying levels of protein expression and correlate with frequent gene amplification in diffuse large B-cell lymphoma

scientific article

BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma

scientific article published on 17 January 2006

BCL2 predicts survival in germinal center B-cell-like diffuse large B-cell lymphoma treated with CHOP-like therapy and rituximab

scientific article

BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma

scientific article

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma

scientific article

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

scientific article (publication date: July 2002)

Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD.

scientific article

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

scientific article published on 12 August 2012

CARMA1 and chromosomal translocations in extranodal marginal zone B-cell lymphomas of MALT type or diffuse large B-cell lymphomas

scientific article published on 17 October 2006

CCL3 (MIP-1α) plasma levels and the risk for disease progression in chronic lymphocytic leukemia

scientific article published on November 29, 2010

CCL3 chemokine expression by chronic lymphocytic leukemia cells orchestrates the composition of the microenvironment in lymph node infiltrates.

scientific article

CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1- mantle cell lymphoma

scientific article published on 11 December 2018

CCND2 rearrangements are the most frequent genetic events in cyclin D1(-) mantle cell lymphoma

scientific article published on 18 December 2012

CD40L mediated alternative NFκB-signaling induces resistance to BCR-inhibitors in patients with mantle cell lymphoma

scientific article published on 24 January 2018

CD52 expression in peripheral T-cell lymphomas determined by combined immunophenotyping using tumor cell specific T-cell receptor antibodies

scientific article published in June 2009

CDK4andMDM2Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-typeINK4a/ARFLocus

article

CIITA or RFX coding region loss of function mutations occur rarely in diffuse large B-cell lymphoma cases and cell lines with low levels of major histocompatibility complex class II expression

scientific article published on 19 February 2009

Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma

scientific article published in July 2006

Case report: A unique pediatric case of a primary CD8 expressing ALK-1 positive anaplastic large cell lymphoma of skeletal muscle

scientific article

Central review of lymphoma diagnosis: still a prerequisite for best patient care in 2014?

scientific article published on 28 January 2014

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.

scientific article

Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling

scientific article published on 01 September 2007

Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma

article

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

scientific article

Chronic lymphocytic leukemia with mutated IgVH1-69 usage: a distinct CLL subgroup with more indolent behavior?

scientific article published on April 2008

Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group

scientific article published on 19 May 2017

Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond

scientific article

Clinical, pathological and genetic features of primary mediastinal large B-cell lymphomas and mediastinal gray zone lymphomas in children

scientific article

Clinicogenetic risk models predict early progression of follicular lymphoma after first-line immunochemotherapy

scientific article published on 14 July 2016

Cognate Nonlytic Interactions between CD8+ T Cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties

scientific article published on 28 January 2019

Coincidence of lymphomatoid granulomatosis, chronic myelomonocytic leukemia, and anaplastic T cell lymphoma after methotrexate therapy for rheumatoid arthritis

scientific article published on 07 July 2018

Colorimetric in situ hybridization identifies MYC gene signal clusters correlating with increased copy number, mRNA, and protein in diffuse large B-cell lymphoma

scientific article published on February 2013

Combination of expression levels of miR-21 and miR-126 is associated with cancer-specific survival in clear-cell renal cell carcinoma

scientific article published on 15 January 2014

Combination therapy with brentuximab vedotin and cisplatin/cytarabine in a patient with primarily refractory anaplastic lymphoma kinase positive anaplastic large cell lymphoma.

scientific article

Combined RNA-expression and 2D-PAGE-screening identifies comprehensive interaction networks affected after bortezomib or enzastaurin exposure of mantle cell lymphoma

scientific article

Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study

scientific article published on August 31, 2012

Comprehensive analysis of GST-pi expression in B-cell lymphomas: Correlation with histological subtypes and survival

scientific article published on July 2008

Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.

scientific article published on April 2007

Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.

scientific article published on 30 June 2004

Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

scientific article

Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas

scientific article published on October 1, 2010

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

scientific article (publication date: 2004)

Conventional chemotherapy (CHOEP-14) with rituximab or high-dose chemotherapy (MegaCHOEP) with rituximab for young, high-risk patients with aggressive B-cell lymphoma: an open-label, randomised, phase 3 trial (DSHNHL 2002-1)

scientific article published on November 16, 2012

Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

scientific article

Cooperative epigenetic modulation by cancer amplicon genes

scientific article

Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma

scientific article published on 26 December 2007

Corticomedullary differentiation and maturational arrest in thymomas

scientific article published on 18 November 2013

Crizotinib in refractory ALK-positive diffuse large B-cell lymphoma: a case report with a short-term response

scientific article

Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases.

scientific article

Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling

scientific article published on 25 August 2005

Cytomorphologic, immunohistochemical, and cytogenetic profiles of follicular lymphoma: 2 types of follicular lymphoma grade 3

scientific article published on 01 May 2002

Decreased major histocompatibility complex class II expression in diffuse large B-cell lymphoma does not correlate with CpG methylation of class II transactivator promoters III and IV.

scientific article

Delineation of chondroid lipoma: an immunohistochemical and molecular biological analysis

scientific article

Delineation of distinct tumour profiles in mantle cell lymphoma by detailed cytogenetic, interphase genetic and morphological analysis

scientific article published on 28 June 2008

Detection of rearrangements and transcriptional up-regulation of ALK in FFPE lung cancer specimens using a novel, sensitive, quantitative reverse transcription polymerase chain reaction assay

scientific article published on 01 March 2014

Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue

scientific article published on 07 January 2014

Diagnostic and prognostic significance of gene expression profiling in lymphomas

scientific article published on October 2007

Differential expression of long non-coding RNAs are related to proliferation and histological diversity in follicular lymphomas

article

Differential gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas

scientific article published in May 2005

Diffuse Large B-cell Lymphomas of Immunoblastic Type Are a Major Reservoir for MYC-IGH Translocations

article

Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status

scientific article published on 5 October 2015

Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction

scientific article published on 26 July 2005

Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.

scientific article published on 24 November 2014

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis

scholarly article

Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs

scientific article published on 15 September 2004

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

scientific article (publication date: 3 February 2000)

Disturbed expression of the T-cell receptor/CD3 complex and associated signaling molecules in CD30+ T-cell lymphoproliferations.

scientific article published on 29 May 2010

Diversity of genomic breakpoints in TFG-ALK translocations in anaplastic large cell lymphomas: identification of a new TFG-ALK(XL) chimeric gene with transforming activity

scientific article

Doubling rituximab in high-risk patients with aggressive B-cell lymphoma -results of the DENSE-R-MegaCHOEP trial

scientific article published on 05 December 2018

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles

scientific article published on 20 August 2018

ERCC1 as predictive biomarker to platinum-based chemotherapy in adrenocortical carcinomas

scientific article published on 29 November 2017

EZH2 mutations are frequent and represent an early event in follicular lymphoma

scientific article published on 19 September 2013

Early development of PAT-SM6 for the treatment of melanoma

scientific article published on August 1, 2013

Efficacy of Nivolumab and AVD in Early-Stage Unfavorable Classic Hodgkin Lymphoma: The Randomized Phase 2 German Hodgkin Study Group NIVAHL Trial

scientific article published on 30 April 2020

Elevated serum free light chains do not predict outcome of elderly patients with aggressive CD20(+) B-cell lymphomas

scientific article published on 27 June 2014

Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications.

scientific article

Epigenetic regulation of CD44in Hodgkin and non-Hodgkin lymphoma

scientific article published on September 29, 2010

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma

scientific article

Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms

scientific article published on 03 February 2014

Establishing Pure Cancer Organoid Cultures: Identification, Selection and Verification of Cancer Phenotypes and Genotypes

scientific article published on 29 May 2019

Evaluation of FoxP3 expression in peripheral T-cell lymphoma

scientific article published on 01 October 2008

Exon-4 Mutations in KRAS Affect MEK/ERK and PI3K/AKT Signaling in Human Multiple Myeloma Cell Lines

scientific article published on 16 February 2020

Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis

scientific article

Expression of TP53 is associated with the outcome of MCL independent of MIPI and Ki-67 in trials of the European MCL Network.

scientific article published in December 2017

Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma

scientific article published in April 2007

Extrafacial indolent CD8-positive cutaneous lymphoid proliferation with unusual symmetrical presentation involving both feet

scientific article published on 19 September 2013

Extranodal involvement of the head and neck region in adult T-cell leukemia/lymphoma: rare, but relevant.

scientific article published in February 2009

FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy.

scientific article published on 9 November 2017

Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffin-embedded tissue

scientific article published on 7 July 2008

Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response

scientific article

Fluorescence in situ analysis of soft tissue tumor associated genetic alterations in formalin-fixed paraffin-embedded tissue

article

Follicular lymphoma grade 3B is a distinct neoplasm according to cytogenetic and immunohistochemical profiles

scientific article

Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations

scientific article published on 26 May 2009

Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial

scientific article published on 01 December 2020

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

scientific article published on 26 September 2016

Frequent occurrence of deletions in primary mediastinal B-cell lymphoma

article

From CLL to Multiple Myeloma - Spleen Tyrosine Kinase (SYK) influences multiple myeloma cell survival and migration

scientific article published on 22 October 2015

GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6.

scientific article

Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma

scientific article published on 26 March 2008

Gemcitabine-Based Chemotherapy in Adrenocortical Carcinoma: A Multicenter Study of Efficacy and Predictive Factors

scientific article published on 19 September 2017

Gene expression predicts overall survival in paraffin-embedded tissues of diffuse large B-cell lymphoma treated with R-CHOP.

scientific article published on 10 June 2008

Gene expression profiling in malignant lymphomas

scientific article published on January 2007

Gene expression profiling of diffuse large B-cell lymphoma

scientific article published on January 2003

Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.

scientific article published on 22 March 2018

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

scientific article

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

scientific article

Gene expression signatures of adult T-cell leukemia: is treatment response prediction on the horizon?

scientific article published on 01 July 2010

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

scientific article published on 19 February 2019

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

scientific article published in April 2018

Genome-wide analysis of pediatric-type follicular lymphoma reveals low genetic complexity and recurrent alterations of TNFRSF14 gene.

scientific article published on 2 June 2016

Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma

scientific article published on 13 September 2013

Genome-wide methylation analyses identify a subset of mantle cell lymphoma with a high number of methylated CpGs and aggressive clinicopathological features.

scientific article published on 16 July 2013

Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis

scientific article

Genomic and Gene Expression Profiling Defines Indolent Forms of Mantle Cell Lymphoma

article

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

scientific article published on 29 March 2019

Genomic deletion and promoter methylation status of Hypermethylated in Cancer 1 (HIC1) in mantle cell lymphoma

scientific article published on 05 July 2008

Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol

scientific article

Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma

scientific article published on 10 December 2014

HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling

scientific article published on 15 November 2016

Hexokinase-2 Expression in MET-positive FDG-negative Multiple Myeloma

scientific article published on 02 November 2018

High TNFRSF14 and low BTLA are associated with poor prognosis in Follicular Lymphoma and in Diffuse Large B-cell Lymphoma transformation

scientific article published on 01 January 2019

High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology.

scientific article published on 23 February 2018

High microvessel density determines a poor outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus chemotherapy.

scientific article

High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation

scientific article published on 12 December 2008

Histiocytic and dendritic cell neoplasms: what have we learnt by studying 67 cases.

scientific article published on 10 July 2017

Histopathological features and their prognostic impact in nodular lymphocyte-predominant Hodgkin lymphoma--a matched pair analysis from the German Hodgkin Study Group (GHSG).

scientific article published on 26 June 2014

Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

scientific article published on 7 September 2006

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

scientific article published on 10 June 2004

Hydroa Vacciniforme-like Skin Lesions in Epstein-Barr-Virus-associated T-cell Lymphoproliferation with Subsequent Development of Aggressive NK/T-cell Lymphoma.

scientific article published on 9 November 2016

Hyper-N-glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma

scientific article published on 24 September 2018

IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

scientific article

IKZF1/3 and CRL4-CRBN E3 ubiquitin ligase mutations and IMiD resistance in multiple myeloma

scientific article published on 26 September 2019

Identification of Primary Mediastinal Large B-cell Lymphoma at Nonmediastinal Sites by Gene Expression Profiling

scientific article

Identification of methylated genes associated with aggressive clinicopathological features in mantle cell lymphoma

scientific article

Identifying functional modules in protein-protein interaction networks: an integrated exact approach

scientific article

IgVH mutational status and clonality analysis of Richter's transformation: diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution

scientific article

Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL.

scientific article published on 24 August 2010

Immunohistochemical methods for predicting cell of origin and survival in patients with diffuse large B-cell lymphoma treated with rituximab

scientific article

Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications--a study from the Lunenburg Lymphoma Biomarker Consortium

scientific article published on March 2007

Impact of miR-21, miR-126 and miR-221 as prognostic factors of clear cell renal cell carcinoma with tumor thrombus of the inferior vena cava

scientific article

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

scientific article

Inactivation of RB1 in mantle-cell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis.

scientific article published on March 2007

Increased MDM2 expression is associated with inferior survival in mantle cell lymphoma, but not related to the MDM2 SNP309

scientific article published on 01 April 2007

Increased tumor cell proliferation in mantle cell lymphoma is associated with elevated insulin-like growth factor 2 mRNA-binding protein 3 expression

scientific article published on 4 May 2012

Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry

scientific article

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases

scientific article published on 26 July 2011

Is there still a point for classical cytogenetic banding analysis in the diagnostic work-up of specimens suspicious for lymphoma?

scientific article published on 01 January 2008

Ki-67 as a prognostic marker in mantle cell lymphoma-consensus guidelines of the pathology panel of the European MCL Network

scientific article

LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability.

scientific article published on 4 February 2011

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy

scientific article published on June 2006

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

scientific article published on 21 October 2013

Livin/BIRC7 expression as malignancy marker in adrenocortical tumors.

scientific article published on 21 December 2016

Localized- and advanced-stage follicular lymphomas differ in their gene expression profiles

scientific article published on 01 January 2020

Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials

scientific article

Loss of MHC class II gene and protein expression in diffuse large B-cell lymphoma is related to decreased tumor immunosurveillance and poor patient survival regardless of other prognostic factors: a follow-up study from the Leukemia and Lymphoma Mol

scientific article published on 19 February 2004

Loss of major histocompatibility class II expression in non-immune-privileged site diffuse large B-cell lymphoma is highly coordinated and not due to chromosomal deletions.

scientific article published on 20 October 2005

Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma

scientific article

Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells

scientific article published on 01 January 2019

MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.

scientific article

MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties

scientific article published on 17 February 2016

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells

scientific article

MYC + diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation

scientific article published on 09 March 2012

MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma

scientific article published on January 18, 2013

Mapping immune processes in intact tissues at cellular resolution

scientific article

Mechanisms and Effects of Loss of Human Leukocyte Antigen Class II Expression in Immune-Privileged Site-Associated B-Cell Lymphoma

scientific article published in May 2006

Memory CD4+ T cells lacking expression of CCR7 promote pro-inflammatory cytokine production in patients with diffuse cutaneous systemic sclerosis

scientific article published on 01 October 2019

Methotrexate-induced lymphoproliferative disorders: regression matters

scientific article published on 22 February 2018

MicroRNA expression, chromosomal alterations, and immunoglobulin variable heavy chain hypermutations in Mantle cell lymphomas.

scientific article

MicroRNA profiles of t(14;18)-negative follicular lymphoma support a late germinal center B-cell phenotype

scientific article published on 29 September 2011

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status

article

Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells

scientific article published on 25 August 2015

Molecular biology and genetics of lymphomas

scientific article published on October 2008

Molecular characteristics of diffuse large B-cell lymphoma in the Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin lymphomas (PETAL) trial: correlation with interim PET and outcome

scientific article published on 19 August 2019

Molecular classification of primary mediastinal large B-cell lymphoma using routinely available tissue specimens

article

Molecular diagnosis of Burkitt's lymphoma

scientific article published in June 2006

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

scientific article

Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling

scientific article published on 28 February 2012

Molecular genetic findings in two cases of sarcomatoid carcinoma of the ureter: evidence for evolution from a common pluripotent progenitor cell?

scientific article published on 12 February 2008

Molecular outcome prediction in mantle cell lymphoma

scientific article published on February 2009

Molecular pathogenesis of follicular lymphoma

scientific article published on 01 December 2008

Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features

scientific article published on 20 August 2012

Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

scientific article

Mutated RAS and constitutively activated Akt delineate distinct oncogenic pathways, which independently contribute to multiple myeloma cell survival

scientific article published on 13 December 2010

Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin's lymphoma and T-cell non-Hodgkin's lymphoma

scientific article published on 26 July 2011

Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma

scholarly article

Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma

scientific article

Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation

scientific article

Natalizumab exerts direct signaling capacity and supports a pro-inflammatory phenotype in some patients with multiple sclerosis

scientific article

New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies

scientific article published on 14 March 2017

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

scientific article

Non-Invasive Imaging Provides Spatiotemporal Information on Disease Progression and Response to Therapy in a Murine Model of Multiple Myeloma

scientific article published on December 26, 2012

Non-invasive bioluminescence imaging to monitor the immunological control of a plasmablastic lymphoma-like B cell neoplasia after hematopoietic cell transplantation

scientific article

Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas

scientific article published on 29 June 2016

Numerical and structural genomic aberrations are reliably detectable in tissue microarrays of formalin-fixed paraffin-embedded tumor samples by fluorescence in-situ hybridization

scientific article

Obinutuzumab and venetoclax induced complete remission in a patient with ibrutinib-resistant non-nodal leukemic mantle cell lymphoma

scientific article published on 21 January 2020

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

scientific article

Oncogenically active MYD88 mutations in human lymphoma

scientific article

Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma

scientific article

PI3K-dependent multiple myeloma cell survival is mediated by the PIK3CA isoform

scientific article

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

scientific article published on 4 September 2013

Paraproteinaemia in Primary Cutaneous Marginal Zone Lymphoma

scientific article published on 01 November 2018

Pathogenesis of mantle-cell lymphoma: all oncogenic roads lead to dysregulation of cell cycle and DNA damage response pathways

scientific article

Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling

scientific article

Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival

scientific article published on 13 February 2007

Positron Emission Tomography-Guided Treatment in Early-Stage Favorable Hodgkin Lymphoma: Final Results of the International, Randomized Phase III HD16 Trial by the German Hodgkin Study Group

scientific article published on 10 September 2019

Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy

scientific article

Potentially oncogenic B-cell activation-induced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL.

scientific article published on 12 December 2007

Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

article

Presence of preserved reactive germinal centers in follicular lymphoma is a strong histopathologic indicator of limited disease stage

scientific article published on 01 December 2005

Primary Cutaneous T-cell Lymphoma with Aberrant Expression of CD20.

scientific article

Primary bone marrow diffuse large B-cell lymphoma affecting distal parts of the legs as a cause of persisting B symptoms

scientific article published on 26 March 2014

Primary cutaneous marginal zone lymphoma with sequential development of nodal marginal zone lymphoma in a patient with selective immunoglobulin A deficiency.

scientific article

Primary cutaneous marginal zone lymphomas with plasmacytic differentiation show frequent IgG4 expression

scientific article published on 14 June 2013

Prognostic Significance of MYC Rearrangement and Translocation Partner in Diffuse Large B-Cell Lymphoma: A Study by the Lunenburg Lymphoma Biomarker Consortium

scientific article published on 09 September 2019

Prognostic Value of Ki-67 Index, Cytology, and Growth Pattern in Mantle-Cell Lymphoma: Results From Randomized Trials of the European Mantle Cell Lymphoma Network

scientific article

Prognostic biomarkers in malignant lymphomas

scientific article published on August 2010

Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.

scientific article published on 14 April 2017

Prognostic significance of immunohistochemical biomarkers in diffuse large B-cell lymphoma: a study from the Lunenburg Lymphoma Biomarker Consortium

scientific article published on 2 May 2011

Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

article

Quantitative gene expression deregulation in mantle-cell lymphoma: correlation with clinical and biologic factors

scientific article published on 11 June 2007

RETRACTED: Immunohistochemical prognostic markers in diffuse large B-cell lymphoma: validation of tissue microarray as a prerequisite for broad clinical applications (a study from the Lunenburg Lymphoma Biomarker Consortium)

retracted scientific article

RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours

scientific article published on 02 February 2019

Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma

scientific article published on 26 May 2016

Rare occurrence of IgVH gene translocations and restricted IgVH gene repertoire in ocular MALT-type lymphoma

scientific article published on 01 February 2008

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

Recurrent mutations of NOTCH genes in follicular lymphoma identify a distinctive subset of tumours.

scientific article published on 18 September 2014

Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation

scientific article published on 13 January 2009

Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma

scientific article

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

scientific article published on December 3, 2001

Report: workshop on mediastinal grey zone lymphoma

scientific article published in July 2005

Report: workshop on mediastinal grey zone lymphoma

article by Sibrand Poppema et al published 6 June 2005 in European Journal of Haematology

Reproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry

scientific article published on 01 December 2019

Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells

scientific article published on April 2004

Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma-a feasibility study using full slide staining

scientific article published on 05 May 2018

SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype.

scientific article

SYK expression in monomorphic epitheliotropic intestinal T-cell lymphoma

scientific article published on 20 October 2017

Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study

scientific article

Selective loss of regulatory T cells in thymomas

scientific article published on 01 December 2004

Signal transduction pathways of mantle cell lymphoma: a phosphoproteome-based study.

scientific article published on November 2008

Single nucleotide polymorphism array profiling of adrenocortical tumors--evidence for an adenoma carcinoma sequence?

scientific article

Single nucleotide polymorphism microarray analysis in cortisol-secreting adrenocortical adenomas identifies new candidate genes and pathways

scientific article published in March 2012

Somatic hypermutation analysis in follicular lymphoma provides evidence suggesting bidirectional cell migration between lymph node and bone marrow during disease progression and relapse

scientific article published on April 12, 2013

Specific detection of CD56 (NCAM) isoforms for the identification of aggressive malignant neoplasms with progressive development

scientific article published on 26 February 2009

Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature

scientific article published on 12 February 2007

Spectral karyotyping and SNP microarray analysis define uniparental disomy (UPD) as a novel mutational mechanism in MSI- and CSI-colorectal cancers.

scientific article

Spectrum and functional validation of PSMB5 mutations in multiple myeloma

scientific article published on 19 July 2018

Stromal gene signatures in large-B-cell lymphomas

scientific article

Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.

scientific article published on 17 June 2008

Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens

scientific article

T-cell repertoires in refractory coeliac disease

scientific article published on 10 February 2017

TP53 mutation and survival in aggressive B cell lymphoma

scientific article published on 14 June 2017

TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations

scientific article (publication date: November 1999)

Targetable genetic alterations of () drive immunoglobulin expression in diffuse large B cell lymphoma

scientific article published on 01 June 2019

Targeted Gene Expression Profile Reveals CDK4 as Therapeutic Target for Selected Patients With Adrenocortical Carcinoma

scientific article published on 16 April 2020

Targeted Molecular Analysis in Adrenocortical Carcinomas: A Strategy Toward Improved Personalized Prognostication

scientific article published on 2 August 2018

Targeted Molecular Analysis in Adrenocortical Carcinomas: A Strategy Toward Improved Personalized Prognostication

Targeting CXCR4 with [68Ga]Pentixafor: a suitable theranostic approach in pleural mesothelioma?

scientific article published on 27 May 2017

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma

scientific journal article

Targeting paraprotein biosynthesis for non-invasive characterization of myeloma biology

scientific article

Targeting protein kinase C in mantle cell lymphoma

scientific article published on 23 February 2016

Targeting the microenvironment

scientific article published on August 1, 2010

Telomere length in mantle cell lymphoma

scientific article published on 14 December 2012

Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1.

scientific article published on 20 January 2014

Th17 and non-Th17 interleukin-17-expressing cells in chronic lymphocytic leukemia: delineation, distribution, and clinical relevance

scientific article published on November 4, 2011

The G protein-coupled estrogen receptor 1 (GPER-1) contributes to the proliferation and survival of mantle cell lymphoma cells

scientific article published on 6 August 2015

The Germinal Center/Activated B-Cell Subclassification Has a Prognostic Impact for Response to Salvage Therapy in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Bio-CORAL Study

scientific article published on September 26, 2011

The Ki67 proliferation index is a quantitative indicator of clinical risk in mantle cell lymphoma

scientific article published on 01 April 2006

The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy

scientific article published on 06 August 2018

The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis

scientific article

The Natural Human IgM Antibody PAT-SM6 Induces Apoptosis in Primary Human Multiple Myeloma Cells by Targeting Heat Shock Protein GRP78

scientific article published on May 7, 2013

The Stromal Cell Marker SPARC Predicts for Survival in Patients With Diffuse Large B-Cell Lymphoma Treated With Rituximab

article

The clinicopathologic spectrum of mature aggressive B cell lymphomas

scientific article

The complex landscape of genetic alterations in mantle cell lymphoma

scientific article

The composition of the microenvironment in follicular lymphoma is associated with the stage of the disease

scientific article published on 15 July 2012

The exomic landscape of t(14;18)-negative diffuse follicular lymphoma with 1p36 deletion.

scientific article published on 28 November 2017

The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kappaB signal transduction pathway

scientific article published on December 2002

The impact of SOCS1 mutations in diffuse large B-cell lymphoma

scientific article published on 12 August 2019

The lymphoma-like polychemotherapy regimen "Dexa-BEAM" in advanced and extramedullary multiple myeloma

scientific article published on 14 February 2014

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

scientific article published on 27 July 2009

The molecular spectrum and clinical impact of DIS3 mutations in multiple myeloma

scientific article published on 17 December 2014

The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival

scientific article

The prognostic impact of variant histology in nodular lymphocyte-predominant Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG)

scientific article published on 07 October 2013

The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma

article

The reliability of immunohistochemical analysis of the tumor microenvironment in follicular lymphoma: a validation study from the Lunenburg Lymphoma Biomarker Consortium

scientific article published on 07 February 2014

The time to relapse correlates with the histopathological growth pattern in nodular lymphocyte predominant Hodgkin lymphoma

scientific article published on 21 August 2019

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

scientific article

Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms

scientific article published on January 2007

Transmission of angioimmunoblastic T-cell lymphoma by bone marrow transplant

scientific article published on 09 October 2014

Treatment and prognosis of mature T-cell and NK-cell lymphoma: an analysis of patients with T-cell lymphoma treated in studies of the German High-Grade Non-Hodgkin Lymphoma Study Group

scientific article published on 21 July 2010

Tumor genetics and survival of thymic neuroendocrine neoplasms: A multi-institutional clinicopathologic study

article

Tumor-associated macrophages and survival in classic Hodgkin's lymphoma

scientific article

Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells

scientific article

USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma

scientific article published on 16 June 2016

Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification

scientific article published on 05 September 2013

Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification

scientific article published on January 2013

Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling.

scientific article

Validation of the MCL35 gene expression proliferation assay in randomized trials of the European Mantle Cell Lymphoma Network

article

Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma

scientific article published on 19 December 2013

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

scientific article

ZAP-70 expression and prognosis in chronic lymphocytic leukaemia

scientific article

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

scientific article published on 20 February 2003

[(11) C]Methionine emerges as a new biomarker for tracking active myeloma lesions

scientific article published on 3 May 2017

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia

scientific article

microRNA expression profiles identify subtypes of mantle cell lymphoma with different clinicobiological characteristics

scientific article published on 02 May 2013

p53 family members in myogenic differentiation and rhabdomyosarcoma development

scientific article

t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2

scientific article published on August 30, 2011