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List of works by Ian Goodfellow

A Cell-based Fluorescence Resonance Energy Transfer (FRET) Sensor Reveals Inter- and Intragenogroup Variations in Norovirus Protease Activity and Polyprotein Cleavage

scientific article published on 11 September 2015

A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation

scientific article

A blueprint for the implementation of a validated approach for the detection of SARS-Cov2 in clinical samples in academic facilities

scientific article published on 01 June 2020

A chimeric N-terminal Escherichia coli--C-terminal Rhodobacter sphaeroides FliG rotor protein supports bidirectional E. coli flagellar rotation and chemotaxis

scientific article published on March 2005

A conserved interaction between a C-terminal motif in Norovirus VPg and the HEAT-1 domain of eIF4G is essential for translation initiation

A novel role for poly(C) binding proteins in programmed ribosomal frameshifting

scientific article published on 02 June 2016

A robust human norovirus replication model in zebrafish larvae: Supplementary data file

A single amino acid substitution in the murine norovirus capsid protein is sufficient for attenuation in vivo.

scientific article published in 2008

Activation of COX-2/PGE2 Promotes Sapovirus Replication via the Inhibition of Nitric Oxide Production

scientific article

Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal Mutagenesis

scientific article

Advances in norovirus biology

scientific article

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells ⬇️

scientific article

Analysis of protein-protein interactions in the feline calicivirus replication complex

article

Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal caliciviruses

scientific article

Both α2,3- and α2,6-linked sialic acids on O-linked glycoproteins act as functional receptors for porcine Sapovirus

scientific article (publication date: June 2014)

COMRADES determines in vivo RNA structures and interactions

scientific article published on 10 September 2018

Calicivirus Reverse Genetics

article

Calicivirus translation initiation requires an interaction between VPg and eIF 4 E.

scientific article

Caliciviruses Differ in Their Functional Requirements for eIF4F Components

scientific article published in Journal of Biological Chemistry

Characterisation of the mob locus from Rhodobacter sphaeroides required for molybdenum cofactor biosynthesis.

scientific article

Characterization of echoviruses that bind decay accelerating factor (CD55): evidence that some haemagglutinating strains use more than one cellular receptor

scientific article published on July 1998

Cloning of thefliIgene fromRhodobacter sphaeroidesWS8 by analysis of a transposon mutant with impaired motility

scientific article published in 1996

Complete genome sequence of canine astrovirus with molecular and epidemiological characterisation of UK strains

scientific article

Correction for Subba-Reddy et al., "VPg-Primed RNA Synthesis of Norovirus RNA-Dependent RNA Polymerases by Using a Novel Cell-Based Assay".

scientific article published on 14 December 2017

Correction: A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation

scientific article published on 11 March 2016

Coxsackie B viruses that use human DAF as a receptor infect pig cells via pig CAR and do not use pig DAF.

scientific article published in January 2002

Coxsackievirus B3-associated myocardial pathology and viral load reduced by recombinant soluble human decay-accelerating factor in mice

scientific article (publication date: 2003)

Detection of Hepatitis E Virus Antibodies in Dogs in the United Kingdom.

scientific article published on 15 June 2015

Detection of protein-protein interactions using tandem affinity purification

scientific article published on January 2014

Development of a reverse-genetics system for murine norovirus 3: long-term persistence occurs in the caecum and colon

scientific article

Development of a strand specific real-time RT-qPCR assay for the detection and quantitation of murine norovirus RNA

scientific article published on 22 May 2012

Development of an optimized RNA-based murine norovirus reverse genetics system

scientific article published on 14 July 2010

Echovirus infection of rhabdomyosarcoma cells is inhibited by antiserum to the complement control protein CD59.

scientific article

Echoviruses bind heparan sulfate at the cell surface.

scientific article published on May 2001

Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19

scientific article published on 19 June 2020

Epigenetic Suppression of Interferon Lambda Receptor Expression Leads to Enhanced Human Norovirus Replication In Vitro

scientific article published on 01 October 2019

Epigenetic suppression of interferon lambda receptor expression leads to enhanced HuNoV replication in vitro

Eukaryotic initiation factor 4E

scientific article published on 24 October 2007

Evidence for human norovirus infection of dogs in the United kingdom

scientific article published on April 2015

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

scientific article

Factors required for the Uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3Dpol) in vitro

scientific article published on June 2005

Favipiravir elicits antiviral mutagenesis during virus replication in vivo

scientific article published on 21 October 2014

Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage ⬇️

scientific article published on 4 May 2016

Feline calicivirus p32, p39 and p30 proteins localize to the endoplasmic reticulum to initiate replication complex formation

scientific article

Feline calicivirus replication: requirement for polypyrimidine tract-binding protein is temperature-dependent

scientific article published on November 2006

First Directly Sequenced Genome of Hepatitis E Virus from the Serum of a Patient from the United Kingdom

scientific article published on 15 September 2016

Functional Analysis of RNA Structures Present at the 3? Extremity of the Murine Norovirus Genome: the Variable Polypyrimidine Tract Plays a Role in Viral Virulence.

scientific article published in October 2010

Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence

scientific article

Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation.

scientific article

Functions of the 5' and 3' ends of calicivirus genomes

scientific article

Generation of anti-complement "prodrugs": cleavable reagents for specific delivery of complement regulators to disease sites

scientific article published on 3 July 2003

Genogroup IV and VI canine noroviruses interact with histo-blood group antigens

scientific article

Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

scientific article published on 08 February 2022

Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

scientific article published on October 2015

Heme Oxygenase-1 Suppresses Bovine Viral Diarrhoea Virus Replication in vitro

scientific article

Hepatitis E in southern Vietnam: Seroepidemiology in humans and molecular epidemiology in pigs.

scientific article

High-resolution functional profiling of the norovirus genome

scientific article

Human Norovirus NS3 has RNA Helicase and Chaperoning Activities

scientific article

Identification of RNA-protein interaction networks involved in the norovirus life cycle

scientific article published on 29 August 2012

Identification of a cis-acting replication element within the poliovirus coding region

scientific article

Identification of amino acids within norovirus polymerase involved in RNA binding and viral replication

scientific article

Identification of protein interacting partners using tandem affinity purification

scientific article published on 25 February 2012

Identification of protein interaction partners in mammalian cells using SILAC-immunoprecipitation quantitative proteomics

scientific article published on 6 July 2014

Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells

scientific article published on 15 May 2019

In memoriam--Richard M. Elliott (1954-2015)

scientific article

In vitro sensitivity of human parainfluenza 3 clinical isolates to ribavirin, favipiravir and zanamivir

scientific article

Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo.

scientific article published on 29 April 2013

Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation

scientific article published on 23 November 2011

Inhibition of coxsackie B virus infection by soluble forms of its receptors: binding affinities, altered particle formation, and competition with cellular receptors.

scientific article

Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants

scientific article published on 8 July 2009

Interactions of CD55 with non-C ligands

scientific article published in 2002

Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites

scientific article published in March 2004

Laboratory support during and after the Ebola virus endgame: towards a sustained laboratory infrastructure

scientific article published on 26 March 2015

MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection

scientific article published on 26 April 2016

Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A

scientific article

Mapping the binding domains on decay accelerating factor (DAF) for haemagglutinating enteroviruses: implications for the evolution of a DAF-binding phenotype

article

MicroRNA miR-24-3p promotes porcine reproductive and respiratory syndrome virus replication through suppression of heme oxygenase-1 expression

scientific article published on 4 February 2015

Model systems for the study of human norovirus Biology

scientific article

Molecular chaperone Hsp90 is a therapeutic target for noroviruses

scientific article published on 8 April 2015

Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection

scientific article

Murine norovirus: propagation, quantification, and genetic manipulation

scientific article

Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication ⬇️

scientific article

Next-generation whole genome sequencing identifies the direction of norovirus transmission in linked patients.

scientific article published on 03 May 2013

Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo

scientific article

Norovirus gene expression and replication

scientific article

Norovirus genome circularization and efficient replication are facilitated by binding of PCBP2 and hnRNP A1.

scientific article published on 14 August 2013

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4

scientific article (publication date: December 2011)

Norovirus translation requires an interaction between the C Terminus of the genome-linked viral protein VPg and eukaryotic translation initiation factor 4G.

scientific article published on 13 June 2014

Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors

scientific article

Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors

Noroviruses

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.

scientific article published on 11 July 2017

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

scientific article published on 08 March 2019

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

scientific article published on 12 August 2019

Noroviruses: a global cause of acute gastroenteritis

scientific article published on 26 June 2014

Nucleolin interacts with the feline calicivirus 3' untranslated region and the protease-polymerase NS6 and NS7 proteins, playing a role in virus replication

scientific article published on 15 June 2011

Pathogenesis of Korean SapelovirusA in piglets and chicks

scientific article

Pathology caused by persistent murine norovirus infection

scientific article published on 13 November 2013

Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylation

scientific article

Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity

scientific article published in 2019

Polypyrimidine tract binding protein functions as a negative regulator of feline calicivirus translation

scientific article

Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor

scientific article published on 10 February 2016

Porcine sapovirus Cowden strain enters LLC-PK cells via clathrin- and cholesterol-dependent endocytosis with the requirement of dynamin II

Porcine sapovirus replication is restricted by the type I interferon response in cell culture

scientific article

Progress towards the prevention and treatment of norovirus infections

scientific article

Protein-RNA linkage and posttranslational modifications of feline calicivirus and murine norovirus VPg proteins

Protein-RNA linkage and posttranslational modifications of feline calicivirus and murine norovirus VPg proteins

article published in 2016

Protein-RNA linkage and posttranslational modifications of feline calicivirus and murine norovirus VPg proteins

scientific article published on 28 June 2016

Purification and characterization of the flagellar basal body of Rhodobacter sphaeroides.

scientific article published on September 2003

RETRACTED: Norovirus RNA synthesis is modulated by an interaction between the viral RNA-dependent RNA polymerase and the major capsid protein, VP1.

scientific article

Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases ⬇️

scientific article

Recovery of genetically defined murine norovirus in tissue culture by using a fowlpox virus expressing T7 RNA polymerase

scientific article

Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.

scientific article published on 3 August 2017

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

scientific article

Reply to Kempf et al.

scientific article published on February 2017

Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days

scientific article

Retraction for Subba-Reddy et al., "Norovirus RNA Synthesis Is Modulated by an Interaction between the Viral RNA-Dependent RNA Polymerase and the Major Capsid Protein, VP1".

scientific article published on 30 November 2017

Reverse genetics mediated recovery of infectious murine norovirus.

scientific article

Role of RNA structure and RNA binding activity of foot-and-mouth disease virus 3C protein in VPg uridylylation and virus replication

scientific article published on October 2006

Sapovirus translation requires an interaction between VPg and the cap binding protein eIF4E.

scientific article

Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

scientific article published on 11 May 2020

Serological evidence for multiple strains of canine norovirus in the UK dog population

scientific article

Spatial and temporal control of norovirus protease activity is determined by polyprotein processing and intermolecular interactions within the viral replication complex

Structural insights into calicivirus attachment and uncoating

scientific article

Structural insights into the transcriptional and translational roles of Ebp1

scientific article

Structure and function analysis of the poliovirus cis-acting replication element (CRE).

scientific article published in January 2003

Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteins

scientific article

Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases

scientific article

The RNA Helicase eIF4A Is Required for Sapovirus Translation

scientific article published on 2 March 2016

The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2

scientific article published on 05 November 2020

The cryo-electron microscopy structure of feline calicivirus bound to junctional adhesion molecule A at 9-angstrom resolution reveals receptor-induced flexibility and two distinct conformational changes in the capsid protein VP1 ⬇️

scientific article published on August 24, 2011

The genome-linked protein VPg of vertebrate viruses — a multifaceted protein ⬇️

scientific article published on 07 October 2011

The molecular pathology of noroviruses

scientific article

The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis

scientific article

The poliovirus 2C cis-acting replication element-mediated uridylylation of VPg is not required for synthesis of negative-sense genomes

scientific article published in September 2003

The short- and long-range RNA-RNA Interactome of SARS-CoV-2

scientific article published on 20 July 2020

The structure of echovirus type 12 bound to a two-domain fragment of its cellular attachment protein decay-accelerating factor (CD 55)

scientific article

UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis

scholarly article by Anna Smielewska et al published 19 September 2018 in Wellcome Open Research

UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis

scientific article published on 26 November 2018

Unrecognised Outbreak: Human parainfluenza virus infections in a pediatric oncology unit. A new diagnostic PCR and virus monitoring system may allow early detection of future outbreaks

scientific article published on 19 September 2018

VPg-primed RNA synthesis of norovirus RNA-dependent RNA polymerases by using a novel cell-based assay

scientific article published on 12 October 2011

Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures

scientific article (2016)

Virus genomes reveal factors that spread and sustained the Ebola epidemic

scientific article (publication date: 12 April 2017)

Zika virus outbreak and the case for building effective and sustainable rapid diagnostics laboratory capacity globally

scientific article

miR-155 induction is a marker of murine norovirus infection but does not contribute to control of replication in vivo.

scientific article

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