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List of works by Peter Macheroux

15N- and 13C-NMR investigations of glucose oxidase from Aspergillus niger

scientific article

3'-Enolpyruvyl-UMP, a novel and unexpected metabolite in nikkomycin biosynthesis

scientific article

6-S-Cysteinylation of Bi-covalently Attached FAD in Berberine Bridge Enzyme Tunes the Redox Potential for Optimal Activity

scientific article published in Journal of Biological Chemistry

8-thiocyanatoflavins as active-site probes for flavoproteins

scientific article published on January 1991

A concerted mechanism for berberine bridge enzyme

scientific article

A homolog of old yellow enzyme in tomato. Spectral properties and substrate specificity of the recombinant protein.

scientific article

A hydrophobic sequence motif common to N-hydroxylating enzymes

scientific article published on 01 February 1998

A novel N,N-8-amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis ⬇️

scientific article published on 12 September 2011

A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase

scientific article

A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro

scientific article published on 30 October 2019

A stereoselective inverting sec-alkylsulfatase for the deracemization of sec-alcohols

scientific article published on 19 July 2011

A unique reaction in a common pathway: mechanism and function of chorismate synthase in the shikimate pathway

scientific article

Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitors

scientific article published on 11 June 2012

Annotating the Plasmodium genome and the enigma of the shikimate pathway

scientific article published on February 2004

Anthranoyl-CoA monooxygenase/reductase from Azoarcus evansii possesses both FMN and FAD in two distinct and independent active sites

scientific article published on 02 April 2015

Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae

scientific article published in February 2001

Asymmetric Amination of Tetralone and Chromanone Derivatives Employing ω-Transaminases

Asymmetric Bioreduction of Activated Alkenes Using Cloned 12-Oxophytodienoate Reductase Isoenzymes OPR-1 and OPR-3 fromLycopersicon esculentum (Tomato): A Striking Change of Stereoselectivity

scholarly article by Mélanie Hall et al published 18 May 2007 in Angewandte Chemie International Edition

Asymmetric Bioreduction of CC Bonds using Enoate Reductases OPR1, OPR3 and YqjM: Enzyme-Based Stereocontrol

scholarly article by Mélanie Hall et al published 22 February 2008 in Advanced Synthesis & Catalysis

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases.

scientific article published on 24 April 2018

Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine

scientific article

Binding of the Oxidized, Reduced, and Radical Flavin Species to Chorismate Synthase. An Investigation by Spectrophotometry, Fluorimetry, and Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopy†

article

Biocatalytic Enantioselective Oxidative CC Coupling by Aerobic CH Activation

scientific article published on 18 January 2011

Biocatalytic Oxidative CC Bond Formation Catalysed by the Berberine Bridge Enzyme: Optimal Reaction Conditions

scholarly article by Verena Resch et al published 26 August 2011 in Advanced Synthesis & Catalysis

Biocatalytic organic synthesis of optically pure (S)-scoulerine and berbine and benzylisoquinoline alkaloids

scientific article published on 19 July 2011

Biochemical evidence that berberine bridge enzyme belongs to a novel family of flavoproteins containing a bi-covalently attached FAD cofactor

scientific article

Bioluminescence emission of bacterial luciferase with 1-deaza-FMN. Evidence for the noninvolvement of N(1)-protonated flavin species as emitters

article

Catalytic and Structural Role of a Conserved Active Site Histidine in Berberine Bridge Enzyme

scientific article

Characterization and cDNA-microarray expression analysis of 12-oxophytodienoate reductases reveals differential roles for octadecanoid biosynthesis in the local versus the systemic wound response

scientific article (publication date: November 2002)

Characterization of YqjM, an Old Yellow Enzyme homolog from Bacillus subtilis involved in the oxidative stress response

scientific article published on 26 March 2003

Characterization of a thermostable NADPH:FMN oxidoreductase from the mesophilic bacterium Bacillus subtilis.

scientific article

Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis

article

Chorismate synthase from the hyperthermophile Thermotoga maritima combines thermostability and increased rigidity with catalytic and spectral properties similar to mesophilic counterparts

scientific article

Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase(1.)

scientific article

Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway

scientific article published on 27 July 2007

Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization

scientific article

Deracemization by simultaneous bio-oxidative kinetic resolution and stereoinversion

scientific article published on 24 February 2014

Determination of free and bound riboflavin in cow’s milk using a novel flavin-binding protein

scientific article published on 12 September 2013

Determination of the pKa value of C115 in MurA (UDP-N-acetylglucosamine enolpyruvyltransferase) from Enterobacter cloacae

scientific article

Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice

scientific article published on 16 June 2020

Direct expression of active spinach glycolate oxidase in Escherichia coli

scientific article published on 01 August 1992

Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability

scientific article

Dissection of contributions from invariant amino acids to complex formation and catalysis in the heteromeric pyridoxal 5-phosphate synthase complex from Bacillus subtilis

scientific article

Electron donation to the flavoprotein NifL, a redox-sensing transcriptional regulator.

scientific article published on June 1998

Enantioselective Oxidative Aerobic Dealkylation of N-Ethyl Benzylisoquinolines by Employing the Berberine Bridge Enzyme

scientific article published on 21 October 2015

Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III

scientific article

Enzymatic reduction and oxidation of fibre-bound azo-dyes

article by S. Pricelius et al published June 2007 in Enzyme and Microbial Technology

Epoxidation of conjugated C=C-bonds and sulfur-oxidation of thioethers mediated by NADH:FMN-dependent oxidoreductases

scientific article published on 26 January 2009

Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding

scientific article

Evidence for the generation of myristylated FMN by bacterial luciferase

scientific article published on 27 March 2017

Expression of spinach glycolate oxidase in Saccharomyces cerevisiae: purification and characterization

scientific article published on 01 May 1991

FAD and substrate analogs as probes for lysine N6-hydroxylase from Escherichia coli EN 222

scientific article

Flavin-dependent quinone reductases

scientific article published on January 2008

Flavogenomics--a genomic and structural view of flavin-dependent proteins

scientific article

Fluorine-19 NMR studies on 8-fluoroflavins and 8-fluoro flavoproteins

scientific article published on 01 March 1990

Functional Roles of the 6-S-Cysteinyl, 8 -N1-Histidyl FAD in Glucooligosaccharide Oxidase from Acremonium strictum

scientific article

Heterologous expression of two FAD-dependent oxidases with (S)-tetrahydroprotoberberine oxidase activity from Arge mone mexicana and Berberis wilsoniae in insect cells

scientific article

Human pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor-1 alpha. Characterization and kinetic analysis of wild-type and mutant enzymes

scientific article published on July 1995

Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations

scientific article

Identification of the reactive cysteine residues in yeast dipeptidyl peptidase III.

scientific article

Induction of apoptosis in yeast by L-amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma

scientific article published in May 2008

Inverting the regioselectivity of the berberine bridge enzyme by employing customized fluorine-containing substrates

scientific article published on 7 September 2012

Involvement of Tyr24 and Trp108 in substrate binding and substrate specificity of glycolate oxidase

scientific article

L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma. Comparative sequence analysis and characterization of active and inactive forms of the enzyme

scientific article published in March 2001

LeSBT1, a subtilase from tomato plants. Overexpression in insect cells, purification, and characterization.

scientific article

Lot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification

scientific article

Lysine 22 in UDP-N-Acetylglucosamine Enolpyruvyl Transferase fromEnterobacter cloacaeIs Crucial for Enzymatic Activity and the Formation of Covalent Adducts with the Substrate Phosphoenolpyruvate and the Antibiotic Fosfomycin†

scientific article published on 01 October 1999

Mechanism of chorismate synthase. Role of the two invariant histidine residues in the active site

scientific article published on 10 December 2003

Mechanism of flavin reduction and oxidation in the redox-sensing quinone reductase Lot6p from Saccharomyces cerevisiae

scientific article published on September 2009

Mechanisms of cell death induction by L-amino acid oxidase, a major component of ophidian venom

scientific article published on 01 August 2006

Medium-Chain Acyl CoA Dehydrogenase: Evidence for Phosphorylation

article

Molecular Mechanisms of Bacterial Bioluminescence

scientific article published on 15 November 2018

Molecular cloning, expression and purification of l-amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma

scientific article published on 21 October 2006

Mutagenic analysis of an invariant aspartate residue in chorismate synthase supports its role as an active site base

scientific article published on 28 February 2007

Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability

scientific journal article

New roles of flavoproteins in molecular cell biology: an unexpected role for quinone reductases as regulators of proteasomal degradation

scientific article published on 14 July 2009

Old Yellow Enzyme-Catalyzed Dehydrogenation of Saturated Ketones

article by Matthias Schittmayer et al published 9 February 2011 in Advanced Synthesis & Catalysis

One-pot deracemization of sec-alcohols: enantioconvergent enzymatic hydrolysis of alkyl sulfates using stereocomplementary sulfatases

scientific article

Orchestration of concurrent oxidation and reduction cycles for stereoinversion and deracemisation of sec-alcohols

scientific article published on 27 September 2008

Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Plant Cell Wall Metabolism

scientific article published on 2 June 2015

Oxidative cyclization of -methyl-dopa by a fungal flavoenzyme of the amine oxidase family

scientific article published in Journal of Biological Chemistry

PLP-dependent enzymes as potential drug targets for protozoan diseases

scientific article published on 24 July 2011

Purification of the yellow fluorescent protein from Vibrio fischeri and identity of the flavin chromophore

scientific article published in July 1987

Quinone reductase acts as a redox switch of the 20S yeast proteasome

scientific article

Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction

scientific article

Reduced flavin: NMR investigation of N5-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst

scientific article

Reductive biotransformation of nitroalkenes via nitroso-intermediates to oxazetes catalyzed by xenobiotic reductase A (XenA)

article

Regioselective para-Carboxylation of Catechols by a Prenylated Flavin Dependent Decarboxylase.

scientific article published on 30 August 2017

Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity

scientific article

Reverse structural genomics: an unusual flavin-binding site in a putative protease from Bacteroides thetaiotaomicron

scientific article published on 20 June 2012

Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enolpyruvyl transferase

scientific article

Role of tyrosine 129 in the active site of spinach glycolate oxidase

scientific article published on 01 May 1993

Spectral detection of an intermediate preceding the excited state in the bacterial luciferase reaction

scientific article published on 01 December 1993

Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH.

scientific article

Stereocomplementary Bioreduction of α,β-Unsaturated Dicarboxylic Acids and Dimethyl Esters using Enoate Reductases: Enzyme- and Substrate-Based Stereocontrol

scientific article published in 2007

Structural and Functional Characterization of NikO, an Enolpyruvyl Transferase Essential in Nikkomycin Biosynthesis

scientific article

Structural and biochemical properties of LuxF from Photobacterium leiognathi

scientific article published on 21 July 2015

Structural and functional impairment of an Old Yellow Enzyme homologue upon affinity tag incorporation

scientific article published in August 2004

Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin.

scientific article

Structural and mechanistic studies reveal the functional role of bicovalent flavinylation in berberine bridge enzyme

scientific article published on 19 May 2009

Structural and thermodynamic insights into the assembly of the heteromeric pyridoxal phosphate synthase from Plasmodium falciparum

scientific article published on 20 September 2007

Structural basis of substrate specificity of plant 12-oxophytodienoate reductases

scientific article

Structure and characterization of the glycan moiety of L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma

scientific article (publication date: July 2001)

Structure and function of YcnD from Bacillus subtilis, a flavin-containing oxidoreductase.

scientific article

Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates

scientific article

Structure and stability of an unusual zinc-binding protein from Bacteroides thetaiotaomicron

scientific article

Structure, biochemical and kinetic properties of recombinant Pst2p from Saccharomyces cerevisiae, a FMN-dependent NAD(P)H:quinone oxidoreductase.

scientific article published on 9 May 2017

Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia meningoseptica.

scientific article

Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase.

scientific article

Studies with lysine N6-hydroxylase. Effect of a mutation in the assumed FAD binding site on coenzyme affinities and on lysine hydroxylating activity

scientific article published in January 1999

Substrate and inhibitor-induced conformational changes in the structurally related enzymes UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS).

scientific article published in July 1999

Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.

scientific article published on 30 March 2016

The 1.3 A crystal structure of the flavoprotein YqjM reveals a novel class of Old Yellow Enzymes

scientific article published on 12 May 2005

The Structure of Glycerol Trinitrate Reductase NerA from Agrobacterium radiobacter Reveals the Molecular Reason for Nitro- and Ene-Reductase Activity in OYE Homologues

scientific article

The family of berberine bridge enzyme-like enzymes: A treasure-trove of oxidative reactions

scientific article

The first structure of dipeptidyl-peptidase III provides insight into the catalytic mechanism and mode of substrate binding

scientific article

The flavoenzyme azobenzene reductase AzoR from Escherichia coli binds roseoflavin mononucleotide (RoFMN) with high affinity and is less active in its RoFMN form.

scientific article published on 10 June 2013

The flavoprotein-catalyzed reduction of aliphatic nitro-compounds represents a biocatalytic equivalent to the Nef-reaction

The flavoproteome of the yeast Saccharomyces cerevisiae

scientific article

The human flavoproteome

scientific article

The redox-sensing quinone reductase Lot6p acts as an inducer of yeast apoptosis

scientific article

The shikimate pathway in apicomplexan parasites: implications for drug development

scientific article published on June 2013

Thermal unfolding of medium-chain acyl-CoA dehydrogenase and iso(3)valeryl-CoA dehydrogenase: study of the effect of genetic defects on enzyme stability

scientific article

Thermodynamic Characterization of the Protein−Protein Interaction in the HeteromericBacillus subtilisPyridoxalphosphate Synthase†

scientific article published on 05 April 2007

Thermodynamic characterization of ligand-induced conformational changes in UDP-N-acetylglucosamine enolpyruvyl transferase

scientific article

Two independent routes of de novo vitamin B6 biosynthesis: not that different after all.

scientific article

UV-visible spectroscopy as a tool to study flavoproteins

scientific article published on 01 January 1999

Unusual C=C bond isomerization of an α,β-unsaturated γ-butyrolactone catalysed by flavoproteins from the old yellow enzyme family

scientific article published on 28 September 2012

Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights

scientific article

X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases

scientific article

X-ray structure of 12-oxophytodienoate reductase 1 provides structural insight into substrate binding and specificity within the family of OYE

scientific article

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