List of works - Daniele Guardavaccaro

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

scientific article

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

scientific article

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

scientific article (publication date: 6 November 2003)

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

scientific article (publication date: 11 March 2004)

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

scientific article (publication date: June 2003)

Identification of a family of human F-box proteins

scientific article

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

scientific article

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

scientific article published on 18 May 2008

Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.

scientific article published on 28 June 2006

Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription

scientific article

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis

scientific article

JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes

scientific article

APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase

scientific article published on August 2007

betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

scientific article

Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

scientific article

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response

scientific article

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

scientific article

Stabilizers and Destabilizers Controlling Cell Cycle Oscillators

scientific article (publication date: April 2006)

Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis

scientific journal article

Oncogenic aberrations of cullin-dependent ubiquitin ligases

scientific article published on March 2004

Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress

scientific article published on 05 June 2012

DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age.

scientific article published in March 2007

PC3 potentiates NGF-induced differentiation and protects neurons from apoptosis

scientific article (publication date: 25 March 2002)

Wnt/β-catenin and MAPK signaling: allies and enemies in different battlefields

scientific article

Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1.

scientific article published on 14 June 2006

A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase

scientific article published on 16 December 2014

Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2.

scientific article published on 27 November 2013

APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit

scientific article

Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes

scientific article

Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomics.

scientific article

Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivo

scientific article

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.

scientific article published on 7 March 2018

USP17- and SCFβTrCP--regulated degradation of DEC1 controls the DNA damage response

scientific article

Nerve growth factor regulates the subcellular localization of the nerve growth factor-inducible protein PC4 in PC12 cells

scientific article (publication date: April 1994)

asb11 is a regulator of embryonic and adult regenerative myogenesis.

scientific article

Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling

scientific article published on 14 August 2014

Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division

scientific article

Nodal signaling range is regulated by proprotein convertase-mediated maturation.

scientific article published on 12 February 2015

Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase

scientific article published on 10 June 2015

Two paths to let the replisome go

scientific article

List of works by Daniele Guardavaccaro

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

Identification of a family of human F-box proteins

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.

Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis

JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes

APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase

betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

Stabilizers and Destabilizers Controlling Cell Cycle Oscillators

Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis

Oncogenic aberrations of cullin-dependent ubiquitin ligases

Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress

DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age.

PC3 potentiates NGF-induced differentiation and protects neurons from apoptosis

Wnt/β-catenin and MAPK signaling: allies and enemies in different battlefields

Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1.

A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase

Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2.

APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit

Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes

Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomics.

Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivo

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.

USP17- and SCFβTrCP--regulated degradation of DEC1 controls the DNA damage response

Nerve growth factor regulates the subcellular localization of the nerve growth factor-inducible protein PC4 in PC12 cells

asb11 is a regulator of embryonic and adult regenerative myogenesis.

Degradation of Tiam1 by casein kinase 1 and the SCFβTrCP ubiquitin ligase controls the duration of mTOR-S6K signaling

Proteasome-dependent degradation of transcription factor activating enhancer-binding protein 4 (TFAP4) controls mitotic division

Nodal signaling range is regulated by proprotein convertase-mediated maturation.

Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase

Two paths to let the replisome go