List of works - Peter Rehling

A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria

scientific article

A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria

scientific article

Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase

scientific article

COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.

scientific article published on 30 January 2018

Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome

scientific article published on 23 December 2015

Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome ⬇️

scientific article published on May 28, 2013

Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import

scientific article published on 31 August 2017

Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria

scientific article

Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies

scientific article

Defining the architecture of the human TIM22 complex by chemical crosslinking

scientific article published on 30 October 2020

Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting

scientific article

Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane

scientific article

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis

scientific article

From TOM to the TIM23 complex - handing over of a precursor

scientific article published on 09 March 2020

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy

scientific article published on 16 November 2017

Human mitochondrial COX1 assembly into cytochrome c oxidase at a glance

scientific article published on 06 February 2015

INA complex liaises the F1Fo-ATP synthase membrane motor modules

scientific article published in November 2017

Import of precursor proteins into isolated yeast mitochondria

scientific article published in January 2006

Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour

scientific article

Integrating mitochondrial translation into the cellular context

scientific article published on October 2015

Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation

scientific article published on January 2011

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

scientific article published on 22 June 2020

MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation

scientific article

MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome-nascent chain complex

scientific article published on 13 November 2019

MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly

scientific journal article

Mapping protein interactions in the active TOM-TIM23 supercomplex

scientific article published on 29 September 2021

Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery

scientific article

Mdm38 is a 14‐3‐3‐Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane ⬇️

scientific article published on July 22, 2011

Mimicking a SURF1 allele reveals uncoupling of cytochrome c oxidase assembly from translational regulation in yeast ⬇️

scientific article published on April 5, 2011

Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space

scientific article published on November 2003

Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

scientific article published on 28 September 2016

Mitochondrial biogenesis: is an old dog still teaching us new tricks? Meeting on the Assembly of the Mitochondrial Respiratory Chain

scientific article published on 7 December 2007

Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome

scientific article

Mitochondrial import and the twin-pore translocase

scientific article published in July 2004

Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex

scientific article published on November 2002

Mitochondrial preprotein translocases as dynamic molecular machines

scientific article published on September 2006

Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

scientific article

Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase

scientific article

Mitochondrial protein import: common principles and physiological networks

scientific article published on 07 June 2012

Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex

scientific article

Motor recruitment to the TIM23 channel's lateral gate restricts polypeptide release into the inner membrane

scientific article published in Nature Communications

On the mechanism of preprotein import by the mitochondrial presequence translocase

scientific article published on 25 January 2010

Oxa1-Ribosome Complexes Coordinate the Assembly of Cytochrome c Oxidase in Mitochondria ⬇️

scientific article published on August 17, 2012

PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages

scientific article published on 17 October 2016

Pam16 has an essential role in the mitochondrial protein import motor

scientific article

Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor

scientific article

Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery

scientific article

Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects

scientific article published on 15 November 2016

Plasticity of Mitochondrial Translation

scientific article

Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions

scientific article published in Nature Communications

Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix

scientific article

Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase

scientific article

Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways

scientific article published on 29 January 2016

Protein insertion into the mitochondrial inner membrane by a twin-pore translocase

scientific article

Protein transport machineries for precursor translocation across the inner mitochondrial membrane

scientific article published on 11 June 2008

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import

scientific article published on 31 December 2018

Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex

scientific article

Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation

scientific article

STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria

scientific article published on 15 May 2013

Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly

scientific article

Signal recognition initiates reorganization of the presequence translocase during protein import ⬇️

scientific article published on February 12, 2013

Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain

scientific article published on 10 December 2007

TIM29 is a subunit of the human carrier translocase required for protein transport

scientific journal article

Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome

scientific article

The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase

scientific article

The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes

scientific article

The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases

scientific article

The carboxyl-terminal third of the dicarboxylate carrier is crucial for productive association with the inner membrane twin-pore translocase

scientific article

The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner

scientific article

The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation

scientific article

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis

scientific article published on 15 November 2017

The mitochondrial oxidase assembly protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers

scientific article

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel

scientific article

The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18.

scientific article

The proteome of Saccharomyces cerevisiae mitochondria

scientific article

The ribosome-associated Mba1 escorts Cox2 from insertion machinery to maturing assembly intermediates

scientific article

The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis

scientific article

Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel

scientific article

Tim50 maintains the permeability barrier of the mitochondrial inner membrane

scientific article

Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex

scientific article published on 7 November 2011

Two distinct membrane potential-dependent steps drive mitochondrial matrix protein translocation.

scientific article published on 23 December 2016

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

scientific article published on March 2014

Unlocking the presequence import pathway

scientific article published on 23 December 2014

Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy

scientific article

List of works by Peter Rehling

A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria

A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria

Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase

COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.

Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome

Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome ⬇️

Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import

Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria

Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies

Defining the architecture of the human TIM22 complex by chemical crosslinking

Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting

Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis

From TOM to the TIM23 complex - handing over of a precursor

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy

Human mitochondrial COX1 assembly into cytochrome c oxidase at a glance

INA complex liaises the F1Fo-ATP synthase membrane motor modules

Import of precursor proteins into isolated yeast mitochondria

Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour

Integrating mitochondrial translation into the cellular context

Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation

MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome-nascent chain complex

MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly

Mapping protein interactions in the active TOM-TIM23 supercomplex

Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery

Mdm38 is a 14‐3‐3‐Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane ⬇️

Mimicking a SURF1 allele reveals uncoupling of cytochrome c oxidase assembly from translational regulation in yeast ⬇️

Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space

Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

Mitochondrial biogenesis: is an old dog still teaching us new tricks? Meeting on the Assembly of the Mitochondrial Respiratory Chain

Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome

Mitochondrial import and the twin-pore translocase

Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex

Mitochondrial preprotein translocases as dynamic molecular machines

Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase

Mitochondrial protein import: common principles and physiological networks

Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex

Motor recruitment to the TIM23 channel's lateral gate restricts polypeptide release into the inner membrane

On the mechanism of preprotein import by the mitochondrial presequence translocase

Oxa1-Ribosome Complexes Coordinate the Assembly of Cytochrome c Oxidase in Mitochondria ⬇️

PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages

Pam16 has an essential role in the mitochondrial protein import motor

Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor

Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery

Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects

Plasticity of Mitochondrial Translation

Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions

Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix

Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase

Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways

Protein insertion into the mitochondrial inner membrane by a twin-pore translocase

Protein transport machineries for precursor translocation across the inner mitochondrial membrane

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import

Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex

Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation

STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria

Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly

Signal recognition initiates reorganization of the presequence translocase during protein import ⬇️

Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain

TIM29 is a subunit of the human carrier translocase required for protein transport

Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome

The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase

The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes

The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases

The carboxyl-terminal third of the dicarboxylate carrier is crucial for productive association with the inner membrane twin-pore translocase

The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner

The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis

The mitochondrial oxidase assembly protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel

The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18.

The proteome of Saccharomyces cerevisiae mitochondria

The ribosome-associated Mba1 escorts Cox2 from insertion machinery to maturing assembly intermediates

The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis

Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel

Tim50 maintains the permeability barrier of the mitochondrial inner membrane