List of works by James McCluskey

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

scientific article

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

scientific article

A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

scientific article

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

scientific article

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

scientific article

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

scientific article published on 01 December 2019

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

scientific article published on 01 November 2019

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.

scientific article published on 31 March 2008

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

scientific article

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

scientific article

A new HLA‐DRB1*04 allele: DRB 1*0420 ⬇️

scientific article published on May 1, 1995

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

scientific article

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

scientific article

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

scientific article

A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule

scientific article

A structural perspective on MHC class Ib molecules in adaptive immunity

scientific article published on 21 July 2006

A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned

scientific article

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.

scientific article published on 26 September 2016

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

scientific article published on 01 July 2020

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

scientific article published on December 2009

Allelic polymorphism in the T cell receptor and its impact on immune responses

scientific article

Alloreactivity

scientific article published in January 2013

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

scientific article published on 8 September 2006

An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant

scientific article

Anergic B cells constitutively present self antigen: Enhanced immunoglobulin receptor-mediated presentation of antigenic determinants by B cells is hierarchical

scholarly article by Dawn Kanost & James McCluskey published May 1994 in European Journal of Immunology

Antibodies to the conserved region of the M protein and a streptococcal superantigen cooperatively resolve toxic shock-like syndrome in HLA-humanized mice

scientific article published on 04 September 2019

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor

scientific article published on 21 May 2009

Antigen recognition by CD1d-restricted NKT T cell receptors.

scientific article

Antigen targeting to major histocompatibility complex class II with streptococcal mitogenic exotoxin Z-2 M1, a superantigen-based vaccine carrier

scientific article published in February 2012

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection

scientific article published on 15 December 2010

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

scientific article

Author Correction: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 02 March 2020

Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease

scientific article

Bringing antigens to attention: a conspiracy of genes, proteins and cells

article

CD1d antigen presentation: treats for NKT cells

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

scientific article

Changes toTissue Antigens

Complement C4 is a marker for adult rheumatoid arthritis ⬇️

scientific article published on July 24, 1982

Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.

scientific article

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

scientific article published on 23 March 2010

Corrigendum: The burgeoning family of unconventional T cells.

scientific article

Cross-reactive memory T cells for Epstein-Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major histocompatibility complex-bound peptide by T cells and its role in alloreactivity

scientific article published on July 1997

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface

scientific article

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

scholarly article

Cytoplasmic accumulation of the 52 kDa Ro/SS-A nuclear autoantigen in transfected cell lines.

scientific article

Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes

scientific article published on 9 October 2017

Detection and Characterisation of Alloreactive T Cells

Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues ⬇️

scientific article published on October 1, 1994

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

scientific article

Direct antigen presentation by DC shapes the functional CD8(+) T-cell repertoire against the nuclear self-antigen La-SSB.

scientific article

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction

scholarly article

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.

scientific article published on 12 March 2018

Diverse MR1-restricted T cells in mice and humans

scientific article published on 21 May 2019

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

scientific article

Donor methylenetetrahydrofolate reductase genotype is associated with graft-versus-host disease in hematopoietic stem cell transplant patients treated with methotrexate.

scientific article published in April 2006

Dressing for the occasion: APCs make antigens presentable

Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex

scientific article published on 17 October 2011

Editorial overview: Allergy and hypersensitivity

scientific article published on 9 September 2016

Electroporation of Antigen-Presenting Cells for T-Cell Recognition and Cytotoxic T-Lymphocyte Priming

scientific article published on 01 January 1995

Electroporation of antibodies into mammalian cells.

scientific article published on January 1995

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

scientific article published on 21 September 2020

Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma.

scientific article published on 7 March 2018

Epitope mimics and determinant spreading: pathways to autoimmunity

scientific article

Expression and functional conservation of the human La (SS-B) nuclear autoantigen in murine cell lines.

scientific article published on October 1993

Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response

scientific article published on 3 June 2008

Fighting infection with your MAITs

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

scientific article published on 16 July 2021

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.

scientific article published on 10 June 2015

Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue

scientific article published on 5 March 2004

Genetic susceptibility and the link between cat exposure and rheumatoid arthritis

scientific article published on October 2000

Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 20 January 2020

Germline-encoded recognition of diverse glycolipids by natural killer T cells

article

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

scholarly article

HLA Restriction of Carbamazepine-Specific T-Cell Clones from an HLA-A*31:01-Positive Hypersensitive Patient

article by Maike Lichtenfels et al published 31 January 2014 in Chemical Research in Toxicology

HLA peptide length preferences control CD8+ T cell responses

scientific article

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

scientific article published in Nature Communications

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

scientific article

Have we cut ourselves too short in mapping CTL epitopes?

scientific article published on 16 November 2005

Hepatoprotective effects of select water-soluble PARP inhibitors in a carbon tetrachloride model

scientific article

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance

scientific article

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

scientific article

How a Home-Grown T Cell Receptor Interacts with a Foreign Landscape

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses

scientific article published on 27 January 2020

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

scientific article published on 16 August 2016

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

scientific article

Human leukocyte antigen phenotype imposes complex constraints on the antigen-specific cytotoxic T lymphocyte repertoire.

scientific article published in January 1997

Human leukocyte antigen-associated drug hypersensitivity

scientific article

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation

scientific article published on 19 August 2016

Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses.

scientific article published on September 2006

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

scientific article published on 01 November 2019

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

scientific article

Identification of a human-specific epitope in a conserved region of the La/SS-B autoantigen

scientific article

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

scientific article published on 22 June 2015

Immune responses to abacavir in antigen-presenting cells from hypersensitive patients.

scientific article

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

scientific article

Immunodominance and immunodomination: critical factors in developing effective CD8+ T-cell-based cancer vaccines

scientific article published on January 2006

Immunodominance hierarchies and gender bias in direct T(CD8)-cell alloreactivity

scientific article published on 18 December 2007

Immunodominant CD4+ responses identified in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant

scholarly article

Immunological aspects of pregnancy

scientific article

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

scientific article

Induction of T-cell immunity to antiretroviral drug-resistant human immunodeficiency virus type 1.

scientific article published on June 2005

Insight into the basis of autonomous immunoreceptor activation

scientific article published on 25 February 2011

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

scientific article published on 27 February 2005

MAIT Cells Upregulate α4β7 in Response to Acute Simian Immunodeficiency Virus/Simian HIV Infection but Are Resistant to Peripheral Depletion in Pigtail Macaques

article

MAIT cells are depleted early but retain functional cytokine expression in HIV infection

scientific article published on 28 October 2014

MAIT cells contribute to protection against lethal influenza infection in vivo

scientific article published in Nature Communications

MAIT cells protect against pulmonary Legionella longbeachae infection ⬇️

scientific article published in Nature Communications

MAIT cells regulate NK cell-mediated tumor immunity

scientific article published on 06 August 2021

MAITs, MR1 and vitamin B metabolites

scientific article published on 18 October 2013

MHC proteins and heparan sulphate proteoglycans regulate murine cytomegalovirus infection

scientific article published on August 1995

MR1 presentation of vitamin B-based metabolite ligands.

scientific article

MR1 presents microbial vitamin B metabolites to MAIT cells

scientific article

Molecular architecture of the αβ T cell receptor-CD3 complex

scientific article

Molecular signature of a public clonotypic autoantibody in primary Sjögren's syndrome: a "forbidden" clone in systemic autoimmunity

scientific article published in November 2011

More than one reason to rethink the use of peptides in vaccine design

scientific article published on May 2007

Mucosa-Associated Invariant T Cells Are Systemically Depleted in Simian Immunodeficiency Virus-Infected Rhesus Macaques

scientific article published on 24 February 2016

Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate

scientific article published in April 2021

Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection

scientific article

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

scientific article

Mucosal-associated invariant T cells in clinical diseases

scientific article

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

scientific article published on 24 July 2020

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.

scientific article published on 4 May 2016

NKT TCR Recognition of CD1d- -C-Galactosylceramide

scientific article

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion

scientific article

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

scientific article

Neo-epitopes are required for immunogenicity of the La/SS-B nuclear antigen in the context of late apoptotic cells

scientific article published on February 2006

Nomenclature and serology of HLA class I and class II alleles

scientific article published on February 2003

Optimization of the MHC class I peptide cargo is dependent on tapasin

scientific article (publication date: April 2002)

Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules?

scientific article published on 29 August 2013

Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

scholarly article

Pro-inflammatory self-reactive T cells are found within murine TCR-αβ(+) CD4(-) CD8(-) PD-1(+) cells.

scientific article published on 06 April 2016

Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity

scientific article

Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells

scientific article

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

scientific article

Resistance to Celiac Disease in Humanized HLA-DR3-DQ2-Transgenic Mice Expressing Specific Anti-Gliadin CD4+ T Cells

scientific article published on 01 June 2009

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

scientific article published on 4 May 2015

Specificity on a knife-edge: the alphabeta T cell receptor

scientific article published on 29 September 2006

Stable expression of the human immunodeficiency virus type 1 envelope glycoprotein in transfected L cells.

scientific article published on December 1992

Structural basis for a major histocompatibility complex class Ib-restricted T cell response

scientific journal article

Structural determinants of T-cell receptor bias in immunity

scientific article published on 17 November 2006

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

scientific article

Structural insight into natural killer T cell receptor recognition of CD1d

scientific article published on January 2007

Structural studies on HLA-G: implications for ligand and receptor binding

scientific article published on 27 October 2006

Structural studies on the alphabeta T-cell receptor

scientific article

Structure of the Chicken CD3  /  Heterodimer and Its Assembly with the   T Cell Receptor

scientific article

T cell allorecognition and MHC restriction--A case of Jekyll and Hyde?

scientific article published on 14 September 2007

T cell allorecognition via molecular mimicry

scientific article

T cell antigen receptor recognition of antigen-presenting molecules

scientific article published on 10 December 2014

T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the hLa class II haplotype DRB1*0301/DQB1*0201

scientific article published on 01 October 2007

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire

scientific article

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

scientific article published on 23 December 2019

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

scientific article published on 25 September 2005

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

scientific article published in November 2015

T cell response to grass pollen allergens: Correlation with skin test reactivity and serum IgE levels

article

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

scientific article

T-cell allorecognition: a case of mistaken identity or déjà vu?

scientific article

T-cell receptor bias and immunity

scientific article published on 18 January 2008

T-cells behaving badly: structural insights into alloreactivity and autoimmunity

scientific article published on 12 August 2008

TAP genes and immunity

scientific article published in October 2004

TCD8 response in diverse outcomes of recurrent exposure to hepatitis C virus

scientific article published on 12 May 2009

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.

scientific article published on 23 July 2015

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance

scientific article

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

article

The Diverse Family of MR1-Restricted T Cells

scientific article published on 5 November 2018

The Effect of Folinic Acid on Methylenetetrahydrofolate Reductase Polymorphisms in Methotrexate-Treated Allogeneic Hematopoietic Stem Cell Transplants

The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule

scientific article

The Structure and Stability of the Monomorphic HLA-G Are Influenced by the Nature of the Bound Peptide

scientific article

The biology and functional importance of MAIT cells

scientific article published on 12 August 2019

The burgeoning family of unconventional T cells

scientific article

The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network

scientific article published on 01 February 2019

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition

scientific article published on March 2008

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

scientific article

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

article

The impact of a large and frequent deletion in the human TCR β locus on antiviral immunity

scientific article

The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family

scientific article

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1.

scientific article published on 04 April 2016

The molecular bases of δ/αβ T cell-mediated antigen recognition.

scientific article

The molecular basis underpinning the potency and specificity of MAIT cell antigens

scientific article published on 02 March 2020

The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length

article

The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease

scientific article published on 21 November 2007

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

scientific article

The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt

scientific article published on 16 December 2005

The shaping of T cell receptor recognition by self-tolerance

scientific article

The spectrum of building-related airway disorders: difficulty in retrospectively diagnosing building-related asthma

scientific article

The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection

scientific article published on 08 February 2011

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

scientific article published on 14 October 2010

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

scientific article

The versatility of the αβ T-cell antigen receptor

scientific article published on 28 January 2014

Three newly identified A*24 alleles: A*2406, A*2413 and A*2414 ⬇️

scientific article published on August 1, 1997

Thyrogastric autoimmunity and MHC associated alleles at the C4 locus in patients with type 1 (insulin-dependent) diabetes ⬇️

scientific article published on 01 July 1984

Tissue specificity of cross-reactive allogeneic responses by EBV EBNA3A-specific memory T cells

scientific article published in March 2011

Understanding the complexity and malleability of T-cell recognition

scientific article published on 13 January 2015

V 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

scientific article

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