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List of works by Poul Nissen

A 9 A resolution X-ray crystallographic map of the large ribosomal subunit

scientific article published in June 1998

A POTluck of peptide transporters

scientific article published on July 27, 2012

A Trojan horse in drug development: targeting of thapsigargins towards prostate cancer cells

scientific article published on March 2009

A bimodular mechanism of calcium control in eukaryotes

scientific article

A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state

scientific article

A first low-resolution difference Fourier map of phosphorus in a membrane protein from near-edge anomalous diffraction

A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate.

scientific article

A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters

scientific article

A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition

scientific article published on 06 November 2020

A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps.

scientific article published on January 2011

A sulfur-based transport pathway in Cu+-ATPases

scientific article published on 8 May 2015

A thermodynamic analysis of fibrillar polymorphism

scientific article published on 9 April 2010

A tomato ER-type Ca2+-ATPase, LCA1, has a low thapsigargin-sensitivity and can transport manganese.

scientific article

Active detergent-solubilized H+,K+-ATPase is a monomer

scientific article

Against the odds? De novo structure determination of a pilin with two cysteine residues by sulfur SAD.

scientific article

Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions

scientific article published on 01 October 2019

An Introduction to P-type ATPase Research

scientific article

Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation

scientific article

Brian Clark has died--marking the end of an era: Professor Brian Frederic Carl Clark, founder of Structural Biology Research at Aarhus University, died on Monday, October 6, 2014. Aged 78 years

scientific article published on 30 October 2014

Brief encounters of cytochrome c.

scientific article published on 13 January 2017

Ca2+ versus Mg2+ coordination at the nucleotide-binding site of the sarcoplasmic reticulum Ca2+-ATPase

scientific article published on 7 February 2007

Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

scientific article

Characterization of a Listeria monocytogenes Ca(2+) pump: a SERCA-type ATPase with only one Ca(2+)-binding site

scientific article

Chloride binding site of neurotransmitter sodium symporters

scientific article published on 2 May 2013

Cognitive deficits caused by a disease-mutation in the α3 Na(+)/K(+)-ATPase isoform

scientific article

Comparing crystal structures of Ca(2+) -ATPase in the presence of different lipids

scientific article

Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments

scientific article published on 20 March 2007

Copper-transporting P-type ATPases use a unique ion-release pathway

scientific article

Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs

scientific article

Crystal Structure of Plasminogen Activator Inhibitor-1 in an Active Conformation with Normal Thermodynamic Stability

scientific article

Crystal Structure of an Ammonia-Permeable Aquaporin

scientific article

Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase

scientific article

Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release

scientific article

Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state

scientific article

Crystal structure of a copper-transporting PIB-type ATPase

scientific article

Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site

scientific article

Crystal structure of the plasma membrane proton pump.

scientific article

Crystal structure of the sodium–potassium pump

scientific article

Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

scientific article

Crystallization and preliminary structural analysis of the Listeria monocytogenes Ca(2+)-ATPase LMCA1

scientific article

Crystallization of a mammalian membrane protein overexpressed in Saccharomyces cerevisiae

scientific article

Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin

scientific article

Crystals of Na+/K+-ATPase with bound cisplatin

scientific article published on 06 September 2014

Crystals of sarcoplasmic reticulum Ca(2+)-ATPase

scientific article

Cyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPase

scientific article

Dephosphorylation of the calcium pump coupled to counterion occlusion

scientific article published in December 2004

Digesting New Elements in Peptide Transport

scholarly article by Joseph A Lyons published in October 2015

Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases

scientific article published in Nature Communications

Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca2+-ATPase Inhibitors and Structure–Activity Relationships

Distribution of Na/K-ATPase alpha 3 isoform, a sodium-potassium P-type pump associated with rapid-onset of dystonia parkinsonism (RDP) in the adult mouse brain

scientific article published on February 2011

Dynamics of P-type ATPase transport revealed by single-molecule FRET.

scientific article published on 8 November 2017

Elongation factor Tu-targeted antibiotics: four different structures, two mechanisms of action

scientific article

Elongation factors in protein biosynthesis

scientific article

Elongation factors on the ribosome

scientific article

Enacyloxin IIa pinpoints a binding pocket of elongation factor Tu for development of novel antibiotics

scientific article published on 28 October 2005

Engineering a Prototypic P-type ATPase Listeria monocytogenes Ca(2+)-ATPase 1 for Single-Molecule FRET Studies.

scientific article published on 8 August 2016

Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy

scientific article

Erratum: Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture

scientific article published in Nature Communications

Erratum: Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes

scientific article published in April 2016

Expression strategies for structural studies of eukaryotic membrane proteins

scientific article published on 27 June 2016

Expression, purification, crystallization and preliminary X-ray analysis of calmodulin in complex with the regulatory domain of the plasma-membrane Ca2+-ATPase ACA8

scientific article

Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation

scientific article published on 12 September 2011

Flexible P-type ATPases interacting with the membrane

scientific article published on 28 June 2012

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

scientific article

Helix unwinding in the effector region of elongation factor EF-Tu-GDP

scientific article

Heterologous expression and purification of an active human TRPV3 ion channel

scientific journal article

HiLiDe—Systematic Approach to Membrane Protein Crystallization in Lipid and Detergent

High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions

scientific article published on 16 March 2017

High-resolution structure of a type IV pilin from the metal-reducing bacterium Shewanella oneidensis.

scientific article

How are ion pumps and agrin signaling integrated?

scientific article

Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture.

scientific article

Identification and function of a cytoplasmic K+ site of the Na+, K+ -ATPase.

scientific article published on 31 July 2008

Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM.

scientific article

Identifying ligand-binding hot spots in proteins using brominated fragments

scientific article

Improved Model of Proton Pump Crystal Structure Obtained by Interactive Molecular Dynamics Flexible Fitting Expands the Mechanistic Model for Proton Translocation in P-Type ATPases

scientific article published on 11 April 2017

In and out of the cation pumps: P-type ATPase structure revisited

scientific article published on 13 July 2010

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

scientific article

Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams

scientific article published on 17 February 2015

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response.

scientific article published on 29 September 2017

Inhibition of ubiquitin proteasome system rescues the defective sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA1) protein causing Chianina cattle pseudomyotonia

scientific article published on 6 October 2014

Initiating heavy-atom-based phasing by multi-dimensional molecular replacement

scientific article

Interactions of a Bacterial Cu(I)-ATPase with a Complex Lipid Environment

scientific article published on 27 June 2018

Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.

scientific article published on 27 November 2017

Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase

scientific article

Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin

scientific article published in December 1996

Isolation, crystallization and crystal structure determination of bovine kidney Na(+),K(+)-ATPase

scientific article published on 16 March 2016

Jens Christian Skou (1918-2018)

scientific article published on 01 July 2018

Large scale identification and categorization of protein sequences using structured logistic regression

scientific article (publication date: 2014)

Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain

scientific article

Localization of a K+ -binding site involved in dephosphorylation of the sarcoplasmic reticulum Ca2+ -ATPase.

scientific article published on 21 September 2004

Macromolecular mimicry

scientific article

Macromolecular mimicry in protein biosynthesis

scientific article published on 01 January 1997

Membrane proteins — do we catch up with the breathless pace of soluble protein structural biology?

scholarly article by Bjørn P. Pedersen published in March 2015

Membrane's Eleven: heavy-atom derivatives of membrane-protein crystals

scientific article published on 18 July 2006

Membrane-protein crystals for neutron diffraction

scientific article published on 30 November 2018

Modulatory and catalytic modes of ATP binding by the calcium pump

scientific article published on 18 May 2006

Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes

scientific article

Na(+),K (+)-ATPase as a docking station: protein-protein complexes of the Na(+),K (+)-ATPase

scientific article published on 14 June 2012

Na+,K+-ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop

scientific article published on 12 November 2014

Namdinator - automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

scientific article published on 27 June 2019

Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells

scientific article published on 10 January 2006

Neurological disease mutations compromise a C-terminal ion pathway in the Na(+)/K(+)-ATPase.

scientific article published on 15 August 2010

Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death

scientific article published on 17 September 2018

On allosteric modulation of P-type Cu(+)-ATPases

scientific article published on 13 March 2013

On the molecular mechanism of flippase- and scramblase-mediated phospholipid transport

scientific article

One way for the gastric proton pump

scientific article published on June 2009

P-Type ATPases

scientific article published on January 1, 2011

P-type ATPases as drug targets: tools for medicine and science.

scientific article published on April 2009

P-type ATPases at a glance

scientific article published on 01 August 2011

Phosphoryl transfer and calcium ion occlusion in the calcium pump

scientific article

Phosphorylation of the Na+,K+-ATPase and the H+,K+-ATPase

scientific article published on 22 April 2010

Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit

scientific article

Probing determinants of cyclopiazonic acid sensitivity of bacterial Ca2+-ATPases

scientific article published on 28 May 2013

Progress toward an understanding of the structure and enzymatic mechanism of the large ribosomal subunit

scientific article

Protein kinase A (PKA) phosphorylation of Na+/K+-ATPase opens intracellular C-terminal water pathway leading to third Na+-binding site in molecular dynamics simulations

scientific article

Protons and how they are transported by proton pumps.

scientific article published on 06 May 2008

Purification and crystallization of the ternary complex of elongation factor Tu:GTP and Phe-tRNAPhe

scientific article published on 01 December 1994

Purification, crystallization and preliminary crystallographic studies of a PacL homologue from Listeria monocytogenes

scientific article published on 27 March 2012

RNA tertiary interactions in the large ribosomal subunit: the A-minor motif

scientific article

Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes

scientific article published in January 2016

Reconstitution of Na(+),K(+)-ATPase in Nanodiscs

scientific article

Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome

scientific article

Regulation of the Ca(2+)-ATPase by cholesterol: a specific or non-specific effect?

scientific article published on 11 August 2015

Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin

scientific article

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

scientific article

S-palmitoylation and s-oleoylation of rabbit and pig sarcolipin

scientific article

SERCA mutant E309Q binds two Ca2+ions but adopts a catalytically incompetent conformation

scientific article

Saposin-Lipoprotein Scaffolds for Structure Determination of Membrane Transporters.

scientific article published on 19 July 2017

Solution structure of the ternary complex between aminoacyl-tRNA, elongation factor Tu, and guanosine triphosphate.

scientific article

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.

scientific article

Special Issue - Signalling. Introduction - Ca2+signalling and transport in health and disease

article

Structural Basis of the Action of Pulvomycin and GE2270 A on Elongation Factor Tu†,‡

scientific article published in 2006

Structural and biophysical characterisation of agrin laminin G3 domain constructs

scientific article published on 30 October 2010

Structural diversity of calmodulin binding to its target sites

scientific article published on May 13, 2013

Structural dynamics of P-type ATPase ion pumps

scientific article published on 01 October 2019

Structural identification of cation binding pockets in the plasma membrane proton pump

scientific article

Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase

scientific article

Structural models of the human copper P-type ATPases ATP7A and ATP7B.

scientific article published in April 2012

Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser.

scientific article published on 11 June 2015

Structure and Function of Cu(I)- and Zn(II)-ATPases

scientific article published on July 2015

Structure and Mechanism of P-Type ATPase Ion Pumps

scientific article published on 24 December 2019

Structure and autoregulation of a P4-ATPase lipid flippase

scientific article published on 26 June 2019

Structure and mechanism of Zn2+-transporting P-type ATPases

scientific article

Structure determination using poorly diffracting membrane-protein crystals: the H+-ATPase and Na+,K+-ATPase case history.

scientific article published on 12 February 2010

Structure of the RACK1 dimer from Saccharomyces cerevisiae

scientific article

Structure of the ternary complex of EF-Tu: macromolecular mimicry in translation

scientific article

Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex

scientific article

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

scientific article

Structures of the heart specific SERCA2a Ca2+-ATPase

scientific article published on 18 February 2019

Targeting thapsigargin towards tumors

scientific article

Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases

scientific article published on 4 January 2011

The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.

scientific article published on 05 May 2009

The C-terminal cavity of the Na,K-ATPase analyzed by docking and electrophysiology

scientific article published on 22 August 2012

The Inner Workings of a Dynamic Duo

scientific article

The Plasmodium falciparum Ca 2+ -ATPase PfATP6: insensitive to artemisinin, but a potential drug target

scientific article

The SERCA residue Glu340 mediates interdomain communication that guides Ca2+ transport

scientific article published on 23 November 2020

The busiest of all ribosomal assistants: elongation factor Tu.

scientific article published on 19 March 2012

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

scientific article

The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA

scientific article

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

scientific article

The most metal-poor damped Lyα systems: insights into chemical evolution in the very metal-poor regime

scientific article

The pumps that fuel a sperm's journey

scientific article

The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter:sodium symporters toward the inward-open state.

scientific article published on 20 March 2017

The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm

scientific article

The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump

scientific article

The social life of ribosomal proteins

scientific article

The structural basis for coupling of Ca2+ transport to ATP hydrolysis by the sarcoplasmic reticulum Ca2+-ATPase

scientific article

The structural basis of calcium transport by the calcium pump

scientific article

The structural basis of ribosome activity in peptide bond synthesis

scientific article

The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations

scientific article published on January 2009

The structures of four macrolide antibiotics bound to the large ribosomal subunit

scientific article

The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold

scientific article published on January 1996

The α2Na+/K+-ATPase is critical for skeletal and heart muscle function in zebrafish

scientific article published on 24 October 2012

The α4 isoform of the Na⁺,K⁺-ATPase is tuned for changing extracellular environments

scientific article published on 17 October 2015

Tracking Ca2+ ATPase intermediates in real time by x-ray solution scattering

scientific article published on 20 March 2020

Transport Pathway in Cu+ P-Type ATPases

Transport mechanism of the sarcoplasmic reticulum Ca2+ -ATPase pump

scientific article

Tuning of the Na,K-ATPase by the beta subunit

scientific article published on 5 February 2016

Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase

scientific article (publication date: May 2003)

V for victory--a V1-ATPase structure revealed

scientific article published on 16 October 2009

Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy

scientific article

Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase

scientific article

What can be learned about the function of a single protein from its various X-ray structures: the example of the sarcoplasmic calcium pump

scientific article

X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

scientific article published on 21 February 2020