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List of works by Andrzej Dziembowski

5' and 3' modifications controlling RNA degradation: from safeguards to executioners

scientific article published on 05 November 2018

A long noncoding RNA promotes parasite differentiation in African trypanosomes

scientific article published on 2022-06-17

A new strategy for gene targeting and functional proteomics using the DT40 cell line

scientific article published on 27 July 2013

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans.

scientific article

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

scientific article

Analysis of 3' and 5' ends of RNA by solid-phase S1 nuclease mapping

scientific article published in July 2001

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

scientific article published on 7 February 2012

Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms: New structural insights to unravel CCR4-NOT mRNA processing machinery

scientific article published on 9 August 2016

Biochemical and structural bioinformatics studies of fungal CutA nucleotidyltransferases explain their unusual specificity toward CTP and increased tendency for cytidine incorporation at the 3'-terminal positions of synthesized tails

scientific article

Biochemistry and Function of RNA Exosomes

scientific article published on 29 September 2012

C16orf57, a gene mutated in poikiloderma with neutropenia, encodes a putative phosphodiesterase responsible for the U6 snRNA 3' end modification

scientific article

Catalytic properties of the eukaryotic exosome

scientific article published on January 2011

Catalytic properties of the eukaryotic exosome.

scientific article published on January 2010

Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism

scientific article

Comparative analysis of deep sequenced methanogenic communities: identification of microorganisms responsible for methane production

scientific article published in 2018

Comprehensive structural and substrate specificity classification of the Saccharomyces cerevisiae methyltransferome

scientific article

Controlling the mitochondrial antisense - role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance

scientific article published on 20 September 2018

Culturable bacteria from pesticides contaminated soils in Poland

scientific article

Cytoplasmic RNA decay pathways - Enzymes and mechanisms

scientific article

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation

scientific article published in April 2021

DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts

scientific article

DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria

scientific article published in November 2017

Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria.

scientific article

Dominant ELOVL1 mutation causes neurological disorder with ichthyotic keratoderma, spasticity, hypomyelination and dysmorphic features

scientific article published in March 2018

Draft Genome Sequence of the Type Strain Pseudomonas jessenii DSM 17150.

scientific article published on 28 September 2017

Draft Genome Sequence of the Type Strain Pseudomonas umsongensis DSM 16611.

scientific article published on 28 September 2017

Draft Genome Sequence of the Type Strain Sphingopyxis bauzanensis DSM 22271

scientific article published on 14 September 2017

Draft Genome Sequence of the Type Strain Sphingopyxis witflariensis DSM 14551.

scientific article published on 7 September 2017

Elimination of 01/A'-A0 pre-rRNA processing by-product in human cells involves cooperative action of two nuclear exosome-associated nucleases: RRP6 and DIS3.

scientific article published on 28 September 2018

Endonucleolytic RNA cleavage by a eukaryotic exosome

scientific article

Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA

scientific article

Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase

scientific article published on February 2016

Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases

scientific article published on 22 July 2020

Genetic and Biochemical Approaches for Analysis of Mitochondrial Degradosome from Saccharomyces cerevisiae

article

Genomic Analysis of γ-Hexachlorocyclohexane-Degrading Sphingopyxis lindanitolerans WS5A3p Strain in the Context of the Pangenome of Sphingopyxis

scientific article published on 06 September 2019

Genomic and Functional Characterization of Environmental Strains of SDS-Degrading spp., Providing a Source of New Sulfatases

scientific article published in 2018

Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

scientific article published on 16 August 2021

Human mitochondrial RNA decay mediated by PNPase-hSuv3 complex takes place in distinct foci

scientific article published on 5 December 2012

Human polynucleotide phosphorylase, hPNPase, is localized in mitochondria.

scientific article

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

scientific article

Identification of a novel human nuclear-encoded mitochondrial poly(A) polymerase

scientific article

Identification of protein partners in mycobacteria using a single-step affinity purification method

scientific article

Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C

scientific article published on 27 April 2020

Interaction Analysis

chapter of a scientific book

Interaction profiling identifies the human nuclear exosome targeting complex

scientific article published on August 2011

Intrinsically disordered N-terminal domain of the Helicoverpa armigera Ultraspiracle stabilizes the dimeric form via a scorpion-like structure

scientific article published on 23 June 2018

Isolation and Characterization of Pseudomonas spp. Strains That Efficiently Decompose Sodium Dodecyl Sulfate

scientific article

Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings

scientific article published on 27 August 2021

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease

scientific article

Localisation of the human hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA

scientific article

Measuring the tail: Methods for poly(A) tail profiling

scientific article published on 2022-05-26

Mechanisms of RNA degradation by the eukaryotic exosome

scientific article published on May 2010

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

scientific article

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

scientific article published in Nature

Mitochondrial protein biogenesis in the synapse is supported by local translation

scientific article published on 18 June 2020

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target

scientific article published on 22 October 2013

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism

scientific article published on 30 July 2010

Nucleoplasmin-like domain of FKBP39 from Drosophila melanogaster forms a tetramer with partly disordered tentacle-like C-terminal segments.

scientific article published on 11 January 2017

Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs

scientific article published on 18 July 2016

PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures

scientific article published on 13 January 2018

Probabilistic approach to predicting substrate specificity of methyltransferases

scientific article

Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systems

scientific article

Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing

scientific article

Proteomic and transcriptomic experiments reveal an essential role of RNA degradosome complexes in shaping the transcriptome of Mycobacterium tuberculosis.

scientific article published in June 2019

Pseudomonas laurylsulfatovorans sp. nov., sodium dodecyl sulfate degrading bacteria, isolated from the peaty soil of a wastewater treatment plant

scientific article published on 11 April 2018

Pseudomonas silesiensis sp. nov. strain A3(T) isolated from a biological pesticide sewage treatment plant and analysis of the complete genome sequence

scientific article

Purification of Eukaryotic Exoribonucleases Following Heterologous Expression in Bacteria and Analysis of Their Biochemical Properties by In Vitro Enzymatic Assays

Quantitative proteomics revealed C6orf203/MTRES1 as a factor preventing stress-induced transcription deficiency in human mitochondria.

scientific article published on 21 June 2019

RNA channelling by the archaeal exosome

scientific article

RNA channelling by the eukaryotic exosome

scientific article

RNA decay machines: the exosome

scientific article published on 23 January 2013

RNA degradation in yeast and human mitochondria

scientific article published in January 2004

Rbs1, a new protein implicated in RNA polymerase III biogenesis in yeast Saccharomyces cerevisiae

scientific article

Recent developments in the analysis of protein complexes

scientific article published on January 2004

Reproducible and efficient new method of RNA 3'-end labelling by CutA nucleotidyltransferase-mediated CC-tailing

scientific article published on 12 November 2021

Sphingopyxis lindanitolerans sp. nov. strain WS5A3p enriched from a pesticide disposal site

scientific article published in 2018

Strategies for the structural analysis of multi-protein complexes: lessons from the 3D-Repertoire project

scientific article published on 2 April 2011

Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.

scientific article published on 8 January 2018

Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression

scientific article published on 5 June 2014

Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine

scientific article published on 12 August 2020

Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family

scientific article

Structure of the yeast Pml1 splicing factor and its integration into the RES complex

scientific article

Subunit architecture of multimeric complexes isolated directly from cells

scientific article

Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations

scientific article published in September 2010

TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals

scientific article published on 2022-11-18

Terminal nucleotidyl transferases (TENTs) in mammalian RNA metabolism

scientific article published on 05 November 2018

The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro

scientific article published on 12 February 2013

The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis

scientific article published on 26 February 2021

The architecture of the Schizosaccharomyces pombe CCR4-NOT complex

scientific article published on 25 January 2016

The eukaryotic RNA exosome: same scaffold but variable catalytic subunits

scientific article published on January 2011

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

scientific article

The human nuclear exosome targeting complex is loaded onto newly synthesized RNA to direct early ribonucleolysis.

scientific article

The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma

scientific article published on 20 September 2017

The yeast THO complex forms a 5-subunit assembly that directly interacts with active chromatin

scientific article published on July 2012

The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism

scientific article

The yeast nuclear gene DSS1, which codes for a putative RNase II, is necessary for the function of the mitochondrial degradosome in processing and turnover of RNA.

scientific article

Three-layered control of mRNA poly(A) tail synthesis in <i>Saccharomyces cerevisiae</i>

scientific article published on 12 August 2021

Two novel C-terminal frameshift mutations in the β-globin gene lead to rapid mRNA decay

scientific article

U6 RNA biogenesis and disease association

scientific article published on June 14, 2013

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s

scientific article published on 6 September 2018

Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system

scientific article published on 28 March 2018

Yeast nuclear PET127 gene can suppress deletions of the SUV3 or DSS1 genes: an indication of a functional interaction between 3' and 5' ends of mitochondrial mRNAs.

scientific article

hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0

scientific article