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List of works by Stefano Bruno

ATP binding to human serine racemase is cooperative and modulated by glycine

scientific article

ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus

scientific article

Allosteric Effectors of Hemoglobin: Past, Present and Future

scientific article published on 4 July 2011

Biochemistry of Hemoglobin

Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin

scientific article

CO Rebinding Kinetics and Molecular Dynamics Simulations Highlight Dynamic Regulation of Internal Cavities in Human Cytoglobin

scientific article

Characterization of ligand migration mechanisms inside hemoglobins from the analysis of geminate rebinding kinetics

scientific article

Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus

scientific article

Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels

scientific article

Correlation of protein functional properties in the crystal and in solution: the case study of T-state hemoglobin

scientific article published on July 2002

Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes

scientific article

Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana

article

Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria

scientific article

Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes

scholarly article by Luca Ronda published in January 2011

Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7

scientific article published on 18 July 2018

Engineered chimeras reveal the structural basis of hexacoordination in globins: a case study of neuroglobin and myoglobin.

scientific article published on 14 October 2014

Enhanced geminate ligand rebinding upon photo-dissociation of silica gel-embedded myoglobin–CO

scientific article published in October 2001

Erratum to: ‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes)

scientific article published on 28 September 2015

Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models.

scientific article

Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca

scientific article

From protein structure to function via single crystal optical spectroscopy

scientific article

Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state

scientific article

Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides

scientific article published on 16 September 2015

Functional characterization of heme proteins encapsulated in wet nanoporous silica gels.

scientific article

Functional properties of the active core of human cystathionine beta-synthase crystals.

scientific article

Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP.

scientific article published on 13 June 2018

Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions

scientific article

Heterogeneous kinetics of the carbon monoxide association and dissociation reaction to nitrophorin 4 and 7 coincide with structural heterogeneity of the gate-loop

scientific article

High and low oxygen affinity conformations of T state hemoglobin

scientific article

High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model

scientific article published on 18 June 2018

Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 fromArabidopsis thaliana

scientific article published on 14 April 2011

Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives

scholarly article by Stefano Bruno published in August 2016

Human serine racemase is nitrosylated at multiple sites.

scientific article published on 30 January 2018

Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins

scientific article published on 23 January 2014

Ligand migration and hexacoordination in type 1 non-symbiotic rice hemoglobin

scientific article

Ligand migration in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

scientific article

Ligand migration through the internal hydrophobic cavities in human neuroglobin

scientific article published on 22 October 2009

Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers.

scientific article

Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin

scientific article

Ligation tunes protein reactivity in an ancient haemoglobin: kinetic evidence for an allosteric mechanism in Methanosarcina acetivorans protoglobin

scientific article

Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes

scientific article

Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form.

scientific article published on 9 January 2017

Modulation of expression and polymerization of hemoglobin Polytaur, a potential blood substitute

scholarly article by Serena Faggiano published in January 2011

Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule.

scientific article

Mutational Effects at the Subunit Interfaces of Human Hemoglobin:  Evidence for a Unique Sensitivity of the T Quaternary State to Changes in the Hinge Region of the α1β2 Interface†

article

New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels

scholarly article

Ormosil gels doped with engineered catechol 1,2 dioxygenases for chlorocatechol bioremediation

scientific article published on 26 February 2014

Oxygen and nitric oxide rebinding kinetics in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

scientific article

Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport

article

Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state

scientific article published on January 2008

PEGylation promotes hemoglobin tetramer dissociation.

scientific article published in July 2009

Polymerization of hemoglobins in Arctic fish: Lycodes reticulatus and Gadus morhua.

scientific article

Polymerized and polyethylene glycol-conjugated hemoglobins: A globin-based calibration curve for dynamic light scattering analysis

scholarly article by Serena Faggiano published in June 2010

Protein crystal microspectrophotometry ⬇️

scientific article published on December 22, 2010

Regulation of human serine racemase activity and dynamics by halides, ATP and malonate

article

Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases

scientific article published on 19 April 2016

Site-directed mutations of human hemoglobin at residue 35beta: a residue at the intersection of the alpha1beta1, alpha1beta2, and alpha1alpha2 interfaces

scientific article

Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline state

scientific article

Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

scientific article published on 5 June 2015

Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme

scientific article

Structural heterogeneity and ligand gating in ferric Methanosarcina acetivorans protoglobin mutants

scientific article

Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants

scientific article published in May 2011

Structural plasticity and functional implications of internal cavities in distal mutants of type 1 non-symbiotic hemoglobin AHb1 from Arabidopsis thaliana.

scientific article

Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.

scientific article published on 13 February 2015

Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin

scientific article

Targeting cystalysin, a virulence factor of treponema denticola-supported periodontitis

scientific article

Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins ⬇️

scientific article published on March 20, 2013

The Greenland shark Somniosus microcephalus-Hemoglobins and ligand-binding properties.

scientific article published on 12 October 2017

The SoxYZ complex carries sulfur cycle intermediates on a peptide swinging arm

scientific article

The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase

scientific article published on 29 November 2020

The reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is controlled by the distal HisE7 and internal hydrophobic cavities

scientific article published on 14 February 2007

Time-resolved methods in Biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis

scientific article published on 18 October 2006

Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration.

scientific article published on 20 March 2008

Trapping Hemoglobin in Rigid Matrices: Fine Tuning of Oxygen Binding Properties by Modulation of Encapsulation Protocols

scholarly article by Stefano Bruno et al published January 2007 in Artificial Cells, Blood Substitutes, and Biotechnology

Trapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus. Direct evidence for a flip-flop mechanism

scientific article

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism

scientific article

X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: a multidisciplinary characterization of catechol 1,2 dioxygenase

scientific article

Zinc-Substituted Myoglobin Is a Naturally Occurring Photo-antimicrobial Agent with Potential Applications in Food Decontamination.

scientific article published on 27 October 2016

‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes)

scientific article published on 15 May 2015

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