List of works - Susanne Gräslund

A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro

scientific article published on 04 March 2014

A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition

scientific article published on 01 June 2018

A High Through-put Platform for Recombinant Antibodies to Folded Proteins

scientific article

A high-stringency proteomics concept aimed for generation of antibodies specific for cDNA-encoded proteins

scientific article published on 01 April 2002

A novel affinity gene fusion system allowing protein A-based recovery of non-immunoglobulin gene products

scientific article

A pilot project to generate affinity reagents to human proteins

scientific article published on 01 October 2008

A roadmap to generate renewable protein binders to the human proteome

scientific article (publication date: 15 May 2011)

A secretory system for bacterial production of high-profile protein targets.

scientific article published on March 2011

Antibody Validation by Immunoprecipitation Followed by Mass Spectrometry Analysis

scientific article published in January 2017

Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+).

scientific article published on 15 February 2016

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation

scientific article published on 29 June 2015

Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition

scientific article

Crystal structure of human diphosphoinositol phosphatase 1

scientific article

Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

scientific article

Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation

scientific article published on 19 October 2011

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation

scientific article

Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library

scientific article published on 3 February 2015

In Vivo Biotinylation of Antigens in E. coli

scientific article published in January 2017

In situ proteolysis for protein crystallization and structure determination

scientific article

Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis

scientific article published on 6 January 2015

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins

scientific article published on 5 October 2015

Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism

scientific article

Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies

scientific article published in Scientific Reports

Protein production and purification

scientific article

Recombinant protein quality evaluation: proposal for a minimal information standard

scientific article (publication date: 30 November 2011)

Recombinant renewable polyclonal antibodies

scientific article published on January 2015

Recovery of upstream cDNA sequences by a PCR-based biotin-capture method

scientific article published on 01 September 1999

Single-vector three-frame expression systems for affinity-tagged proteins

scientific article published on September 2002

Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step

scientific article published on 30 September 2015

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate

scientific article

Structural and biophysical characterization of human myo-inositol oxygenase

scientific article

Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases

scientific article

Substrate specificity and oligomerization of human GMP synthetase

scientific article

Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library

scientific article published on 10 June 2015

The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

scientific article

The structure of the PP2A regulatory subunit B56 gamma: the remaining piece of the PP2A jigsaw puzzle

scientific article

The use of systematic N- and C-terminal deletions to promote production and structural studies of recombinant proteins.

scientific article published on 22 November 2007

Towards proteome scale antibody selections using phage display

scientific article

List of works by Susanne Gräslund

A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro

A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition

A High Through-put Platform for Recombinant Antibodies to Folded Proteins

A high-stringency proteomics concept aimed for generation of antibodies specific for cDNA-encoded proteins

A novel affinity gene fusion system allowing protein A-based recovery of non-immunoglobulin gene products

A pilot project to generate affinity reagents to human proteins

A roadmap to generate renewable protein binders to the human proteome

A secretory system for bacterial production of high-profile protein targets.

Antibody Validation by Immunoprecipitation Followed by Mass Spectrometry Analysis

Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+).

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation

Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition

Crystal structure of human diphosphoinositol phosphatase 1

Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation

Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library

In Vivo Biotinylation of Antigens in E. coli

In situ proteolysis for protein crystallization and structure determination

Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins

Pan-Pathway Based Interaction Profiling of FDA-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism

Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies

Protein production and purification

Recombinant protein quality evaluation: proposal for a minimal information standard

Recombinant renewable polyclonal antibodies

Recovery of upstream cDNA sequences by a PCR-based biotin-capture method

Single-vector three-frame expression systems for affinity-tagged proteins

Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate

Structural and biophysical characterization of human myo-inositol oxygenase

Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases

Substrate specificity and oligomerization of human GMP synthetase

Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library

The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

The structure of the PP2A regulatory subunit B56 gamma: the remaining piece of the PP2A jigsaw puzzle

The use of systematic N- and C-terminal deletions to promote production and structural studies of recombinant proteins.

Towards proteome scale antibody selections using phage display