List of works - Pascale Marchot

1.9-A resolution structure of fasciculin 1, an anti-acetylcholinesterase toxin from green mamba snake venom

scientific article

A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation

scientific article published in August 2017

A. niger protein "EstA", perhaps a new electrotactin, defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily

scientific article published on 01 December 2005

Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex

scientific article

Afaacytin, an alphabeta-fibrinogenase from Cerastes cerastes (Horned Viper) Venom, Activates Purified Factor X and Induces Serotonin Release from Human Blood Platelets

article

Characterization of elapidae snake venom components using optimized reverse-phase high-performance liquid chromatographic conditions and screening assays for alpha-neurotoxin and phospholipase A2 activities

scientific article published on 01 November 1986

Conformational Remodeling of Femtomolar Inhibitor−Acetylcholinesterase Complexes in the Crystalline State

scientific article

Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography

scientific article

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

scientific article published on 24 March 2005

Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors

Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly

scientific article

Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel

scientific article

Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis

scientific article published on 01 December 1989

Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors

scientific article published on 21 March 2017

ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins

scientific article

ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions

scientific article (publication date: 2013)

Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site

scientific article published on 01 March 1999

Enzymatic activity and protein interactions in alpha/beta hydrolase fold proteins: moonlighting versus promiscuity.

scientific article published on February 2012

Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom.

scientific article published in February 1997

Expression of the standard scorpion alpha-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements.

scientific article published on 29 January 2005

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

scientific article

Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related α/β Hydrolase Fold Proteins or Domains-A Structural Perspective

scientific article published on 23 December 2017

Hydrolase versus other functions of members of the alpha/beta-hydrolase fold superfamily of proteins

scientific article published on 01 February 2012

Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1)

scientific article

In vivo synergy of cardiotoxin and phospholipase A2 from the elapid snake Naja mossambica mossambica

scientific article published on 01 January 1987

Inhibition of mouse acetylcholinesterase by fasciculin: Crystal structure of the complex and mutagenesis of fasciculin ⬇️

scientific article published on November 1, 1998

Localization of the toxic site of Naja mossambica cardiotoxins: small synthetic peptides express an in vivo lethality.

scientific article published on June 1988

Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α1(2)βγδ nAChRs.

scientific article published on 21 May 2015

Mechanism of acetylcholinesterase inhibition by fasciculin: a 5-ns molecular dynamics simulation.

scientific article published in May 2002

Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region

scientific article

Monitoring the purification by high-performance liquid chromatography of cardiotoxins from Naja mossambica mossambica using phase-sensitive two-dimensional nuclear magnetic resonance

scientific article published on 01 November 1987

Natural genomic amplification of cholinesterase genes in animals.

scientific article published on 5 April 2017

New friendly tools for users of ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins

scientific article

On the kaliotoxin and dendrotoxin binding sites on rat brain synaptosomes

scientific article published on 01 December 2000

Preface: Cholinergic Mechanisms.

scientific article published in August 2017

Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily

scientific article published on 23 September 2012

Relationships of human α/β hydrolase fold proteins and other organophosphate-interacting proteins

scientific article published on 21 April 2016

Report from the 29th Meeting on Toxinology, “Toxins: From the Wild to the Lab”, Organized by the French Society of Toxinology on 30 November–1 December 2023

scientific article published in 2024

Residues at the Subunit Interfaces of the Nicotinic Acetylcholine Receptor That Contribute to α-Conotoxin M1 Binding ⬇️

scientific article published on April 1, 1998

Selective loss of binding sites for the iodinated alpha-neurotoxin I from Naja mossambica mossambica venom upon enzymatic deglycosylation of Torpedo electric organ membranes

scientific article published on 01 June 1988

Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin.

scientific article

Special Issue on "freshwater and marine toxins"

scientific article published on 20 November 2014

Special issue on «Toxins: from threats to benefits»

scientific article published on 06 August 2013

Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase

scientific article

Structural Insights into Antibody Sequestering and Neutralizing of Na + Channel α-Type Modulator from Old World Scorpion Venom

scientific article

Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion

scientific article

Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.

scientific article published on January 2006

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

scientific article

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

scientific article

Structural insights into AChE inhibition by monoclonal antibodies

scientific article published on 01 December 2005

Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

scientific article

Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions

scientific article

Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility

scientific article published on 01 January 1996

Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: a comparison with acetylcholinesterase.

scientific article published on 25 January 2010

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

scientific article

Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding

scientific article published on 12 July 2006

The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1

scientific article published on 14 September 2020

The neuroligins and the synaptic pathway in Autism Spectrum Disorder

scientific article published on 26 September 2020

The neuroligins and their ligands: from structure to function at the synapse.

scientific article

The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions.

scientific article published on 21 March 2017

Tracking the origin and divergence of cholinesterases and neuroligins: the evolution of synaptic proteins

scientific article published on 5 January 2014

Use of high performance liquid chromatography to demonstrate quantitative variation in components of venom from the scorpion Androctonus australis Hector

scientific article published on 01 January 1987

[Neurotoxicity in mice due to cysteine-rich parts of visna virus and HIV-1 Tat proteins]

scientific article published on 01 January 1990

[The fasciculin-acetylcholinesterase interaction]

scientific article published on 01 January 1999

List of works by Pascale Marchot

1.9-A resolution structure of fasciculin 1, an anti-acetylcholinesterase toxin from green mamba snake venom

A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation

A. niger protein "EstA", perhaps a new electrotactin, defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily

Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex

Afaacytin, an alphabeta-fibrinogenase from Cerastes cerastes (Horned Viper) Venom, Activates Purified Factor X and Induces Serotonin Release from Human Blood Platelets

Characterization of elapidae snake venom components using optimized reverse-phase high-performance liquid chromatographic conditions and screening assays for alpha-neurotoxin and phospholipase A2 activities

Conformational Remodeling of Femtomolar Inhibitor−Acetylcholinesterase Complexes in the Crystalline State

Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors

Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly

Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel

Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis

Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors

ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins

ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions

Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site

Enzymatic activity and protein interactions in alpha/beta hydrolase fold proteins: moonlighting versus promiscuity.

Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom.

Expression of the standard scorpion alpha-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements.

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related α/β Hydrolase Fold Proteins or Domains-A Structural Perspective

Hydrolase versus other functions of members of the alpha/beta-hydrolase fold superfamily of proteins

Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1)

In vivo synergy of cardiotoxin and phospholipase A2 from the elapid snake Naja mossambica mossambica

Inhibition of mouse acetylcholinesterase by fasciculin: Crystal structure of the complex and mutagenesis of fasciculin ⬇️

Localization of the toxic site of Naja mossambica cardiotoxins: small synthetic peptides express an in vivo lethality.

Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α1(2)βγδ nAChRs.

Mechanism of acetylcholinesterase inhibition by fasciculin: a 5-ns molecular dynamics simulation.

Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region

Monitoring the purification by high-performance liquid chromatography of cardiotoxins from Naja mossambica mossambica using phase-sensitive two-dimensional nuclear magnetic resonance

Natural genomic amplification of cholinesterase genes in animals.

New friendly tools for users of ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins

On the kaliotoxin and dendrotoxin binding sites on rat brain synaptosomes

Preface: Cholinergic Mechanisms.

Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily

Relationships of human α/β hydrolase fold proteins and other organophosphate-interacting proteins

Report from the 29th Meeting on Toxinology, “Toxins: From the Wild to the Lab”, Organized by the French Society of Toxinology on 30 November–1 December 2023

Residues at the Subunit Interfaces of the Nicotinic Acetylcholine Receptor That Contribute to α-Conotoxin M1 Binding ⬇️

Selective loss of binding sites for the iodinated alpha-neurotoxin I from Naja mossambica mossambica venom upon enzymatic deglycosylation of Torpedo electric organ membranes

Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin.

Special Issue on "freshwater and marine toxins"

Special issue on «Toxins: from threats to benefits»

Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase

Structural Insights into Antibody Sequestering and Neutralizing of Na + Channel α-Type Modulator from Old World Scorpion Venom

Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion

Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

Structural insights into AChE inhibition by monoclonal antibodies

Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions

Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility

Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: a comparison with acetylcholinesterase.

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding

The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1

The neuroligins and the synaptic pathway in Autism Spectrum Disorder

The neuroligins and their ligands: from structure to function at the synapse.

The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions.

Tracking the origin and divergence of cholinesterases and neuroligins: the evolution of synaptic proteins

Use of high performance liquid chromatography to demonstrate quantitative variation in components of venom from the scorpion Androctonus australis Hector

[Neurotoxicity in mice due to cysteine-rich parts of visna virus and HIV-1 Tat proteins]

[The fasciculin-acetylcholinesterase interaction]