List of works - Sigmar Stricker

A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation

scientific article published on 04 May 2017

A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E.

scientific article published on 16 December 2009

A comparative analysis of Meox1 and Meox2 in the developing somites and limbs of the chick embryo

scientific article published in January 2007

A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C.

scientific article

A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the chicken model

scientific article published on 28 November 2017

A gradient of ROR2 protein stability and membrane localization confers brachydactyly type B or Robinow syndrome phenotypes

scientific article

A misplaced lncRNA causes brachydactyly in humans

scientific article

A molecular pathogenesis for transcription factor associated poly-alanine tract expansions

scientific article

A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range

scientific article published in March 2009

A single amphioxus and sea urchin runt-gene suggests that runt-gene duplications occurred in early chordate evolution

scientific article published in September 2003

Abalone (Haliotis tuberculata) hemocyanin type 1 (HtH1) . Organization of the = 400 kDa subunit, and amino acid sequence of its functional units f, g and h

scientific article published on 01 August 1999

Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders

scientific article

Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2

scientific article

An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression

scientific article published on April 2005

BMP signaling controls muscle mass

scientific journal article

Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis

scientific article published on 19 October 2020

Cloning and expression pattern of chicken Ror2 and functional characterization of truncating mutations in Brachydactyly type B and Robinow syndrome

scientific article published in December 2006

Comparative expression pattern of Odd-skipped related genes Osr1 and Osr2 in chick embryonic development

scientific article

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation

scientific article published on 13 January 2009

Cooperation of BMP and IHH signaling in interdigital cell fate determination.

scientific article

Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis

scientific article

Corrigendum to “Mammalian mitochondrial nitric oxide synthase: Characterization of a novel candidate” [FEBS Lett. 580 (2006) 455-462]

scholarly article published in FEBS Letters

Duplications of BHLHA9 are associated with ectrodactyly and tibia hemimelia inherited in non-Mendelian fashion.

scientific article published on 6 December 2011

Duplications of noncoding elements 5' of SOX9 are associated with brachydactyly-anonychia

scientific article published in August 2009

Editorial: Signaling Pathways in Embryonic Development

scientific article published on 31 August 2017

Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit

scientific article

Evolution of a core gene network for skeletogenesis in chordates

scientific article

Expression of galectin-3 in skeletal tissues is controlled by Runx2.

scientific article published on 25 February 2003

Expression of type XXIII collagen mRNA and protein

scientific article

FGF and ROR2 receptor tyrosine kinase signaling in human skeletal development

scientific article published on January 2011

Faulty initiation of proteoglycan synthesis causes cardiac and joint defects

scientific article

Genome-wide strategies identify downstream target genes of connective tissue-associated transcription factors

scientific article published on 6 March 2018

IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation

scientific article published on 18 August 2017

In addition to being a marker for muscle connective tissue, Odd skipped-related 2 (OSR2) is expressed in differentiated muscle cells during chick development

article

Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment

scientific article published on 9 October 2006

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

scientific article published on 17 November 2020

Mammalian mitochondrial nitric oxide synthase: characterization of a novel candidate

scientific journal article

Mechanisms of digit formation: Human malformation syndromes tell the story ⬇️

scientific article published on February 18, 2011

Microduplications upstream of MSX2 are associated with a phenocopy of cleidocranial dysplasia

scientific article

Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2.

scientific article

Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model

scientific article

Multiple roles for neurofibromin in skeletal development and growth

article

Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein

scientific article

Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

scientific journal article

Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome.

scientific article

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures

scientific journal article

Mutations in WNT7A cause a range of limb malformations, including Fuhrmann syndrome and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome

scientific article

Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2

scientific article

Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.

scientific article published on 9 March 2010

Neurofibromin (Nf1) is required for skeletal muscle development

scientific article

Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury

Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development.

scientific article published on 31 October 2017

Odd-skipped related genes regulate differentiation of embryonic limb mesenchyme and bone marrow mesenchymal stromal cells

scientific article published on 26 July 2011

PDE3A mutations cause autosomal dominant hypertension with brachydactyly

scientific article

Prickle1 is necessary for the caudal migration of murine facial branchiomotor neurons

scientific article

Putting Cells into Context

scientific article published on 5 April 2017

ROR-Family Receptor Tyrosine Kinases

scientific article published on 31 October 2016

Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region

scientific journal article

Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A

Role of Runx genes in chondrocyte differentiation

scientific article

Stable and bicistronic expression of two genes in somite- and lateral plate-derived tissues to study chick limb development

scientific article published on 30 October 2015

The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling

scientific article published on 26 September 2009

The chemokines CXCL12 and CXCL14 differentially regulate connective tissue markers during limb development.

scientific article published on 8 December 2017

The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome

article

The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements

scientific journal article

Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4

scientific article

Whole exome sequencing identifies FGF16 nonsense mutations as the cause of X-linked recessive metacarpal 4/5 fusion

scientific article

Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling

scientific article

skNAC and Smyd1 in transcriptional control

scientific article published on 07 July 2015

List of works by Sigmar Stricker

A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation

A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E.

A comparative analysis of Meox1 and Meox2 in the developing somites and limbs of the chick embryo

A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C.

A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the chicken model

A gradient of ROR2 protein stability and membrane localization confers brachydactyly type B or Robinow syndrome phenotypes

A misplaced lncRNA causes brachydactyly in humans

A molecular pathogenesis for transcription factor associated poly-alanine tract expansions

A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range

A single amphioxus and sea urchin runt-gene suggests that runt-gene duplications occurred in early chordate evolution

Abalone (Haliotis tuberculata) hemocyanin type 1 (HtH1) . Organization of the = 400 kDa subunit, and amino acid sequence of its functional units f, g and h

Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders

Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2

An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression

BMP signaling controls muscle mass

Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis

Cloning and expression pattern of chicken Ror2 and functional characterization of truncating mutations in Brachydactyly type B and Robinow syndrome

Comparative expression pattern of Odd-skipped related genes Osr1 and Osr2 in chick embryonic development

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation

Cooperation of BMP and IHH signaling in interdigital cell fate determination.

Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis

Corrigendum to “Mammalian mitochondrial nitric oxide synthase: Characterization of a novel candidate” [FEBS Lett. 580 (2006) 455-462]

Duplications of BHLHA9 are associated with ectrodactyly and tibia hemimelia inherited in non-Mendelian fashion.

Duplications of noncoding elements 5' of SOX9 are associated with brachydactyly-anonychia

Editorial: Signaling Pathways in Embryonic Development

Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit

Evolution of a core gene network for skeletogenesis in chordates

Expression of galectin-3 in skeletal tissues is controlled by Runx2.

Expression of type XXIII collagen mRNA and protein

FGF and ROR2 receptor tyrosine kinase signaling in human skeletal development

Faulty initiation of proteoglycan synthesis causes cardiac and joint defects

Genome-wide strategies identify downstream target genes of connective tissue-associated transcription factors

IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation

In addition to being a marker for muscle connective tissue, Odd skipped-related 2 (OSR2) is expressed in differentiated muscle cells during chick development

Induction of macrophage chemotaxis by aortic extracts of the mgR Marfan mouse model and a GxxPG-containing fibrillin-1 fragment

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

Mammalian mitochondrial nitric oxide synthase: characterization of a novel candidate

Mechanisms of digit formation: Human malformation syndromes tell the story ⬇️

Microduplications upstream of MSX2 are associated with a phenocopy of cleidocranial dysplasia

Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2.

Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model

Multiple roles for neurofibromin in skeletal development and growth

Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein

Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome.

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures

Mutations in WNT7A cause a range of limb malformations, including Fuhrmann syndrome and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome

Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2

Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.

Neurofibromin (Nf1) is required for skeletal muscle development

Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury

Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury

Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development.

Odd-skipped related genes regulate differentiation of embryonic limb mesenchyme and bone marrow mesenchymal stromal cells

PDE3A mutations cause autosomal dominant hypertension with brachydactyly

Prickle1 is necessary for the caudal migration of murine facial branchiomotor neurons

Putting Cells into Context

ROR-Family Receptor Tyrosine Kinases

Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region

Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A

Role of Runx genes in chondrocyte differentiation

Stable and bicistronic expression of two genes in somite- and lateral plate-derived tissues to study chick limb development

The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling

The chemokines CXCL12 and CXCL14 differentially regulate connective tissue markers during limb development.

The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome

The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements

Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4

Whole exome sequencing identifies FGF16 nonsense mutations as the cause of X-linked recessive metacarpal 4/5 fusion

Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling

skNAC and Smyd1 in transcriptional control