Search filters

List of works by Or Gozani

A Meier-Gorlin syndrome mutation impairs the ORC1-nucleosome association.

scientific article published on 24 February 2015

A PHD finger motif in the C terminus of RAG2 modulates recombination activity

scientific journal article

A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin

scientific article published on 24 February 2016

A Proteomic Strategy Identifies Lysine Methylation of Splicing Factor snRNP70 by the SETMAR Enzyme

scientific article published on 20 March 2015

A chemical method for labeling lysine methyltransferase substrates.

scientific article published on 17 November 2010

A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation

scientific article

A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation

scientific article published on 11 April 2013

A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.

scientific article

A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction

scientific article

A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site

scientific article

A proteomic approach for the identification of novel lysine methyltransferase substrates

scientific article published on 24 October 2011

ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.

scientific article published on 6 May 2016

Accumulation of a novel spliceosomal complex on pre-mRNAs containing branch site mutations

scientific article published on October 1995

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.

scholarly article

An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation

scientific article published on 07 January 2020

An unexpected journey: lysine methylation across the proteome

scientific article

Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription

scientific article

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules

scientific article published on 02 October 2019

CUL4B: trash talking at chromatin.

scientific article published on August 2011

Cancer epigenetics: Reading the future of leukaemia.

scientific article

Cardioinformatics: the nexus of bioinformatics and precision cardiology

scientific article published on 04 December 2019

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.

scientific article

Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells.

scientific article published on 21 September 2017

Characterization of a protein complex containing spliceosomal proteins SAPs 49, 130, 145, and 155

scientific article

Chd5 requires PHD-mediated histone 3 binding for tumor suppression

scientific journal article

Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

scientific article published on 17 March 2016

Correction: Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies

Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells

scientific article published on August 1998

DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation

scientific article published on 03 May 2021

Decoding Chromatin Goes High Tech ⬇️

scientific article published on September 17, 2010

Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation

scientific article published on 16 July 2020

Emerging technologies to map the protein methylome.

scientific article

Enterovirus pathogenesis requires the host methyltransferase SETD3

scientific article published on 16 September 2019

Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks

scientific article

Everybody's welcome: The big tent approach to epigenetic drug discovery.

scientific article published on 20 September 2011

Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A

scientific article

HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail.

scientific article

HeartBioPortal

scientific article published on 16 April 2019

Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor

scientific article

Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time.

scientific article published on 23 November 2015

Histone Methylation in Chromatin Signaling

Histone lysine methyltransferases in biology and disease

scientific article published on 03 October 2019

Histone modifications for chromatin dynamics and cellular plasticity

scientific article published on 01 June 2017

Histone-binding domains: strategies for discovery and characterization

scientific article

Hypoxia-induced methylation of a pontin chromatin remodeling factor

scientific article

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

scientific article

ING4 Mediates Crosstalk between Histone H3 K4 Trimethylation and H3 Acetylation to Attenuate Cellular Transformation

scientific article

Life and death in paradise.

scientific article published in June 2002

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

scientific article

METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis

scientific article published on 03 January 2019

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

scientific article

Methylation by Set9 modulates FoxO3 stability and transcriptional activity.

scientific article

Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses.

scientific article

Methylation of the retinoblastoma tumor suppressor by SMYD2

scientific article

Methyltransferase-like 21C (METTL21C) methylates alanine tRNA synthetase at Lys-943 in muscle tissue

scientific article published on 01 July 2020

Modification of protein sub-nuclear localization by synthetic phosphoinositides: evidence for nuclear phosphoinositide signaling mechanisms

scientific article published on 30 September 2005

Modulation of p53 function by SET8-mediated methylation at lysine 382

scientific article

Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain

scientific article

Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome

scientific article published on 22 September 2016

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases

scientific article published on 23 December 2020

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2

scientific article (publication date: 6 July 2006)

NMR assignments and histone specificity of the ING2 PHD finger

scientific article published on April 2009

NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming

scientific article published on November 2011

Negative regulation of hypoxic responses via induced Reptin methylation.

scientific article

New marks on the block: Set5 methylates H4 lysines 5, 8 and 12.

scientific article published on 12 June 2012

Nonhistone Lysine Methylation in the Regulation of Cancer Pathways

scientific article published on 31 August 2016

Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase.

scientific article published in June 2016

Nuclear PI5P, Uhrf1, and the road not taken.

scientific article published on June 2014

Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage

scientific article published on January 2013

On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.

scientific article

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

scientific article

Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis

scientific article

Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36.

scientific article

Proteome-wide enrichment of proteins modified by lysine methylation.

scientific article

PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

scientific article published on 16 February 2006

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

scientific article

RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation

scientific article

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

scientific article

Regulation of p53 function by lysine methylation

scientific article

Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation

scientific article published on 20 May 2021

Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling

scientific article published on 07 October 2008

SETD3 is an actin histidine methyltransferase that prevents primary dystocia.

scientific article published on 10 December 2018

SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

scientific article published on 13 May 2020

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

scientific article

SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair

scientific article

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

scientific article

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

scientific article

Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons

scientific article published on 17 January 2014

Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation.

scientific article

Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling

scientific article

Structural Basis for the Unique Multivalent Readout of Unmodified H3 Tail by Arabidopsis ORC1b BAH-PHD Cassette.

scientific article published on 08 February 2016

Structural Insight into p53 Recognition by the 53BP1 Tandem Tudor Domain

scientific article

Structural basis for the target specificity of actin histidine methyltransferase SETD3

scientific article published on 06 August 2019

Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling

scientific article

Structure–activity relationships of methyl-lysine reader antagonists

scientific article published in 2012

Systematic Analysis of Known and Candidate Lysine Demethylases in the Regulation of Myoblast Differentiation

scientific article

TRIM24 links a non-canonical histone signature to breast cancer

scientific article

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

scientific article

The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression ⬇️

scientific article

The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor

scientific article

The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.

scientific article published on 29 September 2015

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

scientific article

The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.

scientific article

The fellowships of the INGs

scientific article

The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2

scientific article

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate

scientific article

Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates.

scientific article published on November 2010

Paulina is supported by:

About Paulina

Help