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List of works by Jesús Prieto

A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver

scientific article published on 25 July 2014

A RIG-I 2CARD-MAVS200 Chimeric Protein Reconstitutes IFN-β Induction and Antiviral Response in Models Deficient in Type I IFN Response.

scientific article

A Semliki forest virus vector engineered to express IFNα induces efficient elimination of established tumors.

scientific article published on 7 July 2011

A Versatile Vector for In Vivo Monitoring of Type I Interferon Induction and Signaling.

scientific article

A blood-tumor barrier limits gene transfer to experimental liver cancer: the effect of vasoactive compounds.

scientific article published in November 2000

A bone substitute composed of polymethylmethacrylate and alpha-tricalcium phosphate: results in terms of osteoblast function and bone tissue formation

scientific article published on December 2002

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.

scientific article published on 4 March 2013

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

scientific article

A fusion protein between streptavidin and the endogenous TLR4 ligand EDA targets biotinylated antigens to dendritic cells and induces T cell responses in vivo.

scientific article published on 05 September 2013

A multidrug resistance 3 gene mutation causing cholelithiasis, cholestasis of pregnancy, and adulthood biliary cirrhosis

scientific article published in April 2003

A novel strategy for the generation of angiostatic kringle regions from a precursor derived from plasminogen.

scientific article published in December 2002

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector.

scientific article

A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice.

scientific article

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage

scientific article published in February 2003

A retrospective comparative analysis of the effect of Y90-radioembolization on the survival of patients with unresectable hepatocellular carcinoma

scientific article published on 01 November 2009

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury

scientific article published in April 2003

AAV vectors transduce hepatocytes in vivo as efficiently in cirrhotic as in healthy rat livers

scientific article published on 18 August 2011

Abnormal expression of anion exchanger genes in primary biliary cirrhosis

scientific article published on 01 August 1993

Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins.

scientific article

Abnormal sympathetic and renal response to sodium restriction in compensated cirrhosis

scientific article published in November 1991

Adeno-associated virus liver transduction efficiency measured by in vivo [18F]FHBG positron emission tomography imaging in rodents and nonhuman primates.

scientific article published on 6 April 2011

Adenoviral gene transfer of interleukin 12 into tumors synergizes with adoptive T cell therapy both at the induction and effector level

scientific article published in January 2000

Adenovirus-mediated CD40 ligand gene therapy in a rat model of orthotopic hepatocellular carcinoma

scientific article

Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors

article

Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases

scientific article published in December 2004

Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis

scientific article

Alpha(v)beta(3) integrin-mediated adenoviral transfer of interleukin-12 at the periphery of hepatic colon cancer metastases induces VCAM-1 expression and T-cell recruitment

scientific article

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies

scientific article

Altered liver gene expression in CCl4-cirrhotic rats is partially normalized by insulin-like growth factor-I.

scientific article published in March 2002

Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.

scientific article published on June 2006

Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumors.

scientific article

Amphiregulin: a new growth factor in hepatocarcinogenesis.

scientific article published on 26 February 2007

Amphiregulin: an early trigger of liver regeneration in mice.

scientific article

An oncolytic adenovirus controlled by a modified telomerase promoter is attenuated in telomerase-negative cells, but shows reduced activity in cancer cells

scientific article published on 23 June 2005

Analysis of Prognostic Factors After Yttrium-90 Radioembolization of Advanced Hepatocellular Carcinoma

scientific article published on 07 January 2010

Anchoring interferon alpha to apolipoprotein A-I reduces hematological toxicity while enhancing immunostimulatory properties

scientific article published on 2 May 2011

Anion exchanger 2 is critical for CD8(+) T cells to maintain pHi homeostasis and modulate immune responses

scientific article published on 11 March 2014

Anion exchanger 2 is essential for spermiogenesis in mice

scientific article

Anti-ICAM-2 monoclonal antibody synergizes with intratumor gene transfer of interleukin-12 inhibiting activation-induced T-cell death

scientific article published on September 2003

Anticardiolipin antibodies in chronic hepatitis C: implication of hepatitis C virus as the cause of the antiphospholipid syndrome.

scientific article

Antifibrogenic effect in vivo of low doses of insulin-like growth factor-I in cirrhotic rats.

scientific article published in May 2001

Antioxidant status and glutathione metabolism in peripheral blood mononuclear cells from patients with chronic hepatitis C

scientific article published on 01 November 1999

Antitumor effect of allogenic fibroblasts engineered to express Fas ligand (FasL).

scientific article published on December 1998

Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein.

scientific article

Arteriovenous shunting, hemodynamic changes, and renal sodium retention in liver cirrhosis

scientific article

Assessment of biliary bicarbonate secretion in humans by positron emission tomography

scientific article published on 01 July 1999

Atrial natriuretic factor in cirrhosis: relationship to renal function and hemodynamic changes.

scientific article published in August 1994

Autophagic response in the Rabbit Hemorrhagic Disease, an animal model of virally-induced fulminant hepatic failure

scientific article published on 04 February 2014

Bicarbonate secretion of mouse cholangiocytes involves Na(+)-HCO(3)(-) cotransport in addition to Na(+)-independent Cl(-)/HCO(3)(-) exchange.

scientific article published in March 2010

Bicarbonate-rich choleresis induced by secretin in normal rat is taurocholate-dependent and involves AE2 anion exchanger

scientific journal article

Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat.

scientific article

Bioabsorbable scaffold for in situ bone regeneration

scientific article published on 11 August 2006

Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma

scientific article

Blood vessel formation after soft-tissue implantation of hyaluronan-based hydrogel supplemented with copper ions

scientific article published in June 2005

Bone tissue cultures: an in vitro model for the evaluation of bone defect healing after L-arginine and L-lysine administration

scientific article published in July 2001

CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis

scientific article published on 15 September 2015

Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane.

scientific article published on 27 April 2016

Cardiotrophin-1 decreases intestinal sugar uptake in mice and in Caco-2 cells.

scientific article

Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation

scientific article published on 19 December 2013

Cardiotrophin-1 is a key regulator of glucose and lipid metabolism.

scientific article

Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis

scientific article published on 01 March 2007

Cardiotrophin-1 promotes a high survival rate in rabbits with lethal fulminant hepatitis of viral origin

scientific article published on 5 October 2011

Cardiotrophin-1 stimulates lipolysis through the regulation of main adipose tissue lipases.

scientific article published on 28 October 2014

Cellular immunity to hepatitis C virus core protein and the response to interferon in patients with chronic hepatitis C.

scientific article published on September 1998

Characterization of an immunologically conserved epitope from hepatitis C virus E2 glycoprotein recognized by HLA-A2 restricted cytotoxic T lymphocytes

scientific article published on February 2001

Characterization of bone defect repair in young and aged rat femur induced by xenogenic demineralized bone matrix

scientific article published in September 2002

Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection

scientific article published on 26 October 2013

Chronic alcohol abuse and endosseous implants: linkage of in vitro osteoblast dysfunction to titanium osseointegration rate

scientific article published on 6 October 2007

Chronic exposure to IFNα drives medullar lymphopoiesis towards T-cell differentiation in mice.

scientific article published on 24 February 2015

Circulating adrenomedullin in cirrhosis: relationship to hyperdynamic circulation

scientific article

Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection.

scientific article published on 11 March 2015

Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses

scientific article

Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells

scientific article

Combination therapy with interferon-alpha plus N-acetyl cysteine for chronic hepatitis C: a placebo controlled double-blind multicentre study

scientific article published in August 2000

Combined gene therapy with suicide gene and interleukin-12 is more efficient than therapy with one gene alone in a murine model of hepatocellular carcinoma.

scientific article published in February 2000

Combined immunization with adjuvant molecules poly(I:C) and anti-CD40 plus a tumor antigen has potent prophylactic and therapeutic antitumor effects

scientific article published on 13 June 2007

Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model.

scientific article

Comparative in vitro study on a ultra-high roughness and dense titanium coating

scientific article

Comparison of calcitonin, alendronate and fluorophosphate effects on ovariectomized rat bone

scientific article published in September 2001

Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation

scientific article

Conversion from calcineurin inhibitors to mycophenolate mofetil in liver transplant recipients with diabetes mellitus

scientific article published in August 2003

Conversion of liver transplant recipients on cyclosporine with renal impairment to mycophenolate mofetil

scientific article published on 01 September 1999

Covalently-linked hyaluronan promotes bone formation around Ti implants in a rabbit model

scientific article

Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering

scientific article

Cytoskeletal organization and functional changes in monocytes from patients with chronic hepatitis B: relationship with viral replication

scientific article published on 01 May 1989

De Novo neoplasia after liver transplantation: an analysis of risk factors and influence on survival

scientific article published on 01 January 2005

Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis

scientific article published on 01 January 1997

Defective regulation of cholangiocyte Cl-/HCO3(-) and Na+/H+ exchanger activities in primary biliary cirrhosis.

scientific article

Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8.

scientific article

Detection of anti-hepatitis C virus antibodies by ELISA using synthetic peptides

scientific article published in April 1993

Detection of hepatitis C virus antibodies with new recombinant antigens: assessment in chronic liver diseases

scientific article

Development of Endothelial-Specific Single Inducible Lentiviral Vectors for Genetic Engineering of Endothelial Progenitor Cells.

scientific article

Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer

scientific article

Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability.

scientific article

Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide

scientific article published in May 1999

Disturbed synthesis of insulinlike growth factor I and its binding proteins may influence renal function changes in liver cirrhosis

scientific article published on 01 June 2001

Diversity of killer cell immunoglobulin-like receptor (KIR) genotypes and KIR2DL2/3 variants in HCV treatment outcome

scientific article

Ductular morphogenesis and functional polarization of normal human biliary epithelial cells in three-dimensional culture

scientific article published in July 2001

Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes.

scientific article published on 20 June 2013

Effect of L-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats

scientific article

Effect of adenovirus-mediated RNA interference on endogenous microRNAs in a mouse model of multidrug resistance protein 2 gene silencing

scientific article published on 04 October 2006

Effect of spironolactone on renal prostaglandin excretion in patients with liver cirrhosis and ascites

scientific article published on 01 January 1986

Effect of trabecular orientation on mechanical resistance and ultrasound propagation in specimens of equine vertebrae

scientific article published in December 2003

Effect of ursodeoxycholic acid on methionine adenosyltransferase activity and hepatic glutathione metabolism in rats

scientific article published on May 2002

Effective angiostatic treatment in a murine metastatic and orthotopic hepatoma model

scientific article

Effective antitumour mono- and combination therapy by gene delivery of angiostatin-like molecule and interleukin-12 in a murine hepatoma model

scientific article

Effectiveness of lamivudine in treatment of acute recurrent hepatitis B after liver transplantation

scientific article published on 01 June 1998

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8(+) T cells

scientific article published in December 2010

Efficacy and toxicity of intra-arterial cisplatin and etoposide for advanced hepatocellular carcinoma

scientific article

Efficacy of antibacterial-loaded coating in an in vivo model of acutely highly contaminated implant

scientific article

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

scientific article

Engineering Th determinants for efficient priming of humoral and cytotoxic T cell responses

scientific article published on 01 June 2003

Enhanced T cell responses against hepatitis C virus by ex vivo targeting of adenoviral particles to dendritic cells

scientific article published on 14 May 2011

Enhanced responsiveness to CNS-induced natriuresis in anesthetized nonascitic cirrhotic rats

scientific article published in June 1991

Enhanced therapeutic effect using sequential administration of antigenically distinct oncolytic viruses expressing oncostatin M in a Syrian hamster orthotopic pancreatic cancer model.

scientific article published on 16 December 2015

Enhanced urinary excretion of cGMP in liver cirrhosis. Relationship to hemodynamic changes, neurohormonal activation, and urinary sodium excretion

scientific article published on 01 July 1997

Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus

scientific article published in May 2005

Epidemiological, clinical and therapeutic associations of hepatitis C types in western European patients

scientific article published on May 1996

Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.

scientific article

Eradication of liver-implanted tumors by Semliki Forest virus expressing IL-12 requires efficient long-term immune responses

scientific article published on 11 February 2013

Establishment of an orthotopic tumour model for hepatocellular carcinoma and non-invasive in vivo tumour imaging by high resolution ultrasound in mice

scientific article published on May 2004

Expression of Wilms' tumor suppressor in the liver with cirrhosis: relation to hepatocyte nuclear factor 4 and hepatocellular function

scientific article published in July 2003

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.

scientific article published on January 2005

Expression of interferon-alpha subtypes in peripheral mononuclear cells from patients with chronic hepatitis C: a role for interferon-alpha5.

scientific article

Factors influencing the production of recombinant SV40 vectors

scientific article

Factors related to increased resting energy expenditure in men with liver cirrhosis.

scientific article published on 9 November 2015

Future therapies for hepatocellular carcinoma.

scientific article

Gene expression analysis during acute hepatitis C virus infection associates dendritic cell activation with viral clearance.

scientific article published on 8 October 2015

Gene therapy for liver diseases: recent strategies for treatment of viral hepatitis and liver malignancies ⬇️

scientific article published on January 1, 2002

Gene therapy of cancer with interleukin-12.

scientific article published in January 2003

Gene therapy of liver diseases: A 2011 perspective ⬇️

scientific article published on July 22, 2011

Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12.

scientific article

Gene therapy of viral hepatitis and hepatocellular carcinoma.

scientific article

Gene transfer to liver cancer cells of B7-1 plus interleukin 12 changes immunoeffector mechanisms and suppresses helper T cell type 1 cytokine production induced by interleukin 12 alone

scientific article published on 01 January 2000

Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12.

scientific article published in February 2001

Genetics in liver diseases

scientific article published on 04 April 2007

HNF1alpha upregulates the human AE2 anion exchanger gene (SLC4A2) from an alternate promoter

scientific article published on November 2003

Harnessing high density lipoproteins to block transforming growth factor beta and to inhibit the growth of liver tumor metastases

scientific article

Helper cell-independent antitumor activity of potent CD8(+) T cell epitope peptide vaccines is dependent upon CD40L.

scientific article published on 05 December 2013

Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice.

scientific article

Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: different patterns of response to interferon treatment

scientific article published in November 1993

Hepatic differentiation of mouse iPS cells and analysis of liver engraftment potential of multistage iPS progeny

scientific article

Hepatitis B and C viral infections in patients with hepatocellular carcinoma

scientific article published on September 1992

Hepatitis B virus occult infection in subjects with persistent isolated anti-HBc reactivity

scientific article published in March 1993

Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

scientific article

Hepatitis C virus envelope components alter localization of hepatocyte tight junction-associated proteins and promote occludin retention in the endoplasmic reticulum.

scientific article published on October 2008

Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.

scientific article published on 26 September 2010

Hepatitis C virus infection of primary tupaia hepatocytes leads to selection of quasispecies variants, induction of interferon-stimulated genes and NF-kappaB nuclear translocation.

scientific article published on November 2005

Hepatoprotective effects of insulin-like growth factor I in rats with carbon tetrachloride-induced cirrhosis

article

Herpes zoster after liver transplantation: incidence, risk factors, and complications.

scientific article published in September 2004

Histomorphometric bone modifications induced by growth hormone treatment in a rabbit model of short bowel syndrome

scientific article published in March 2004

Histomorphometric, ultrastructural and microhardness evaluation of the osseointegration of a nanostructured titanium oxide coating by metal-organic chemical vapour deposition: an in vivo study

scientific article published in November 2004

Human osteoblast cultures from osteoporotic and healthy bone: biochemical markers and cytokine expression in basal conditions and in response to 1,25(OH)2D3.

scientific article

Human osteopenic bone-derived osteoblasts: essential amino acids treatment effects

scientific article published in February 2003

Hyaluronic acid injections protect patellar tendon from detraining-associated damage

scientific article published on 13 March 2015

Hydroxyapatite-Based Biomaterials vs. Autologous Bone Graft in Spinal Fusion: An in Vivo Animal Study.

scientific article published on 8 April 2014

IFN-alpha gene therapy for woodchuck hepatitis with adeno-associated virus: differences in duration of gene expression and antiviral activity using intraportal or intramuscular routes

scientific article published in July 2005

IFN-alpha5 mediates stronger Tyk2-stat-dependent activation and higher expression of 2',5'-oligoadenylate synthetase than IFN-alpha2 in liver cells

scientific article published on August 2004

IL-12 gene therapy for cancer: in synergy with other immunotherapies

scientific article published in March 2001

Identification and characterization of a T-helper peptide from carcinoembryonic antigen.

scientific article published on April 2004

Identification of CD4+ and CD8+ T cell epitopes of woodchuck hepatitis virus core and surface antigens in BALB/c mice.

scientific article published on July 2010

Identification of HLA-B27-restricted cytotoxic T lymphocyte epitope from carcinoembryonic antigen

scientific article

Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice

scientific article

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

scientific article

Immune complexes in epidemic (type A) hepatitis. Detection by three methods using laser nephelometry.

scientific article published on September 1981

Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein

scientific article

Immunohistochemical detection of chloride/bicarbonate anion exchangers in human liver

scientific article published on 01 June 1994

Immunological landscape and immunotherapy of hepatocellular carcinoma

scientific article

Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I

scientific article published on 01 October 1997

Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences.

scientific article published on July 2010

Implication of human N-alpha-acetyltransferase 5 in cellular proliferation and carcinogenesis.

scientific article published on 15 September 2008

Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.

scientific article published on May 2004

In situ localization of anion exchanger-2 in the human kidney

scientific article published on February 2000

In utero gene therapy: current challenges and perspectives.

scientific article

In vitro and in vivo comparative study of chimeric liver-specific promoters

scientific article published in March 2003

In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1.

scientific article published in July 2008

In vitro and in vivo response to nanotopographically-modified surfaces of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and polycaprolactone

scientific article published in January 2006

In vitro response of primary rat osteoblasts to titania/hydroxyapatite coatings compared with transformed human osteoblast-like cells

scientific article published on August 2002

In vivo effect of two different pulsed electromagnetic field frequencies on osteoarthritis

scientific article published on 5 February 2014

In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity

scientific article published in September 2000

In vivo preclinical efficacy of a PDLLA/PGA porous copolymer for dental application

scientific article

Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice.

scientific article published on 13 April 2006

Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector.

scientific article published on February 2006

Increased liver stiffness values in patients with heart failure

scientific article published in June 2013

Increased synthesis of systemic prostacyclin in cirrhotic patients

scientific article published on 01 March 1986

Induction of cytotoxic T-cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus

scientific article published on February 1997

Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex

scientific article published in February 2005

Induction of immunosuppressive molecules and regulatory T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse model of liver cancer

scientific article published in October 2007

Induction of murine liver damage by overexpression of CD40 ligand provides an experimental model to study fulminant hepatic failure.

scientific article published on August 2006

Induction of potent and long-lasting CD4 and CD8 T-cell responses against hepatitis C virus by immunization with viral antigens plus poly(I:C) and anti-CD40.

scientific article published on 22 January 2007

Induction of sensitivity to ganciclovir in human hepatocellular carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase

scientific article

Inflammation, HCC and sex: IL-6 in the centre of the triangle

scientific article published on 5 December 2007

Influence of a zirconia sandblasting treated surface on peri-implant bone healing: An experimental study in sheep

scientific article published on 31 January 2009

Influence of density, elasticity, and structure on ultrasound transmission through trabecular bone cylinders

scientific article

Influence of impaired liver methionine metabolism on the development of vascular disease and inflammation.

scientific article

Influence of tumor characteristics on the outcome of liver transplantation among patients with liver cirrhosis and hepatocellular carcinoma

scientific article published in July 2001

Inhibiting expression of specific genes in mammalian cells with 5' end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA.

scientific article

Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation.

scientific article

Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases

scientific article

Inhibitors of the lipoxygenase arachidonic acid pathway impair glycocholate efflux in isolated rat hepatocytes

scientific article published on May 1991

Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial

scientific article published on 01 October 2005

Insulin-like growth factor I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats

scientific article published in March 2010

Insulin-like growth factor-I reverts testicular atrophy in rats with advanced cirrhosis

scientific article published on 01 March 2000

Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates

scientific article

Interferon alfa subtypes and levels of type I interferons in the liver and peripheral mononuclear cells in patients with chronic hepatitis C and controls

scientific article published on 01 June 1999

Interleukin-12 inhibits liver-specific drug-inducible systems in vivo

scientific article published on 22 November 2007

Interleukins in chronic active hepatitis B. Relationship with viral markers.

scientific article published in August 1987

Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration

scientific article

Intracerebroventricular infusion of sodium chloride-rich artificial cerebrospinal fluid in rats induces natriuresis and releases an inhibitor of prostaglandin synthesis

scientific article published in May 1984

Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice

scientific article published in September 2006

Intrahepatic injection of recombinant adeno-associated virus serotype 2 overcomes gender-related differences in liver transduction

scientific article published on June 2006

Intratumoral coinjection of two adenoviruses, one encoding the chemokine IFN-gamma-inducible protein-10 and another encoding IL-12, results in marked antitumoral synergy

scientific article

Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas

scientific article published in October 1999

Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas.

scientific article published on 14 December 2004

Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells

scientific article

L-arginine and L-lysine stimulation on cultured human osteoblasts

scientific article

Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.

scientific article published on 12 July 2011

Leucine stimulates procollagen α1(I) translation on hepatic stellate cells through ERK and PI3K/Akt/mTOR activation

scientific article published in 2006

Liver Transplant Recipients Older Than 60 Years Have Lower Survival and Higher Incidence of Malignancy

scientific article published on 01 November 2003

Liver changes in patients with hyperthyroidism

scientific article published on 01 August 1991

Liver failure caused by herpes simplex virus thymidine kinase plus ganciclovir therapy is associated with mitochondrial dysfunction and mitochondrial DNA depletion

scientific article published on March 2003

Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosis

scientific article published on 5 October 2006

Liver transplantation in cirrhotic patients with diabetes mellitus: midterm results, survival, and adverse events

scientific article published on 01 March 2001

Liver transplantation in patients with hepatocellular carcinoma across Milan criteria

scientific article published on 01 March 2008

Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein A-I.

scientific article published on 12 March 2015

Long-term metabolic correction of Wilson's disease in a murine model by gene therapy.

scientific article published on 23 September 2015

Low doses of insulin-like growth factor-I improve nitrogen retention and food efficiency in rats with early cirrhosis

scientific article published on 01 January 1997

Lysophosphatidic acid is a potential mediator of cholestatic pruritus

scientific article

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer

scientific article published on 30 June 2016

Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis

scientific article

Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair

scientific article published on 16 October 2013

Methylthioadenosine phosphorylase gene expression is impaired in human liver cirrhosis and hepatocarcinoma

scientific article

Microbiological and pharmacological tests on new antibiotic-loaded PMMA-based composites for the treatment of osteomyelitis

scientific article published on 22 August 2011

Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.

scientific article

Modulation of regulatory T-cell activity in combination with interleukin-12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B.

scientific article

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

scientific article

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

scientific article

Molecular profiling of hepatocellular carcinoma in mice with a chronic deficiency of hepatic s-adenosylmethionine: relevance in human liver diseases

scientific article published in April 2006

Monocyte disorder causing cellular immunodeficiency: a family study

scientific article

Monocyte-derived dendritic cells from HCV-infected patients transduced with an adenovirus expressing NS3 are functional when stimulated with the TLR3 ligand poly(I:C).

scientific article

Multipotent Adult Progenitor Cells (MAPC) contribute to hepatocarcinoma neovasculature.

scientific article published on 2 October 2007

Naloxone-reversible monocyte dysfunction in patients with chronic fatigue syndrome

New polymers for drug delivery systems in orthopaedics: in vivo biocompatibility evaluation

scientific article published in October 2004

New strategies to enhance gene therapy efficiency

scientific article

New therapies for hepatocellular carcinoma.

scientific article published on June 2006

Non-specific protein-DNA interactions control I-CreI target binding and cleavage

scientific article

Nonmelanoma skin cancer after liver transplantation. Study of risk factors.

scientific article published on September 2005

Novel role for amphiregulin in protection from liver injury

scientific article

Nuclear factor-kappa B in the liver of patients with chronic hepatitis C: decreased RelA expression is associated with enhanced fibrosis progression

scientific article published in November 2001

Nuclear α1-antichymotrypsin promotes chromatin condensation and inhibits proliferation of human hepatocellular carcinoma cells.

scientific article

Oncostatin M Enhances the Antiviral Effects of Type I Interferon and Activates Immunostimulatory Functions in Liver Epithelial Cells

scientific article (publication date: April 2009)

Opioid peptides modulate the organization of vimentin filaments, phagocytic activity, and expression of surface molecules in monocytes

scientific article

Optimization of the Tet-on system to regulate interleukin 12 expression in the liver for the treatment of hepatic tumors

scientific article published on April 2004

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice

scientific article

Osteoblasts cultured from osteoporotic bone: a comparative investigation on human and animal-derived cells

scientific article published on August 2003

Osteogenesis of large segmental radius defects enhanced by basic fibroblast growth factor activated bone marrow stromal cells grown on non-woven hyaluronic acid-based polymer scaffold

scientific article published in February 2002

Osteointegration in Custom-made Porous Hydroxyapatite Cranial Implants: From Reconstructive Surgery to Regenerative Medicine

scientific article published on 25 March 2015

Osteopenia in rats with liver cirrhosis: beneficial effects of IGF-I treatment

scientific article published on 01 January 1998

Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes.

scientific article published on 3 January 2014

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.

scientific article published on 20 September 2010

Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis.

scientific article published on July 2003

Partial splenic embolization in the treatment of thrombocytopenia after liver transplantation

scientific article published in February 1997

Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy.

scientific article

Phase 1-2 pilot clinical trial in patients with decompensated liver cirrhosis treated with bone marrow-derived endothelial progenitor cells.

scientific article

Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria

scientific article published on 17 May 2016

Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors.

scientific article published on April 2004

Plasma levels of substance P in liver cirrhosis: relationship to the activation of vasopressor systems and urinary sodium excretion

scientific article published on 01 January 1995

Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria

scientific article published on 23 September 2009

Positron emission tomography and gene therapy: basic concepts and experimental approaches for in vivo gene expression imaging.

scientific article published in July 2004

Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients

scientific article

Positron emission tomography use in the diagnosis and follow up of Takayasu's arteritis.

scientific article published in July 2005

Prediction of the response of chronic hepatitis C to interferon alfa: a statistical analysis of pretreatment variables.

scientific article

Preliminary investigations on a new gentamicin and vancomycin-coated PMMA nail for the treatment of bone and intramedullary infections: An experimental study in the rabbit

scientific article

Proceedings: Serum ferritin in patients with iron overload and with acute and chronic liver disease

scientific article published in April 1974

Production of interleukin-2 in response to synthetic peptides from hepatitis C virus E1 protein in patients with chronic hepatitis C: relationship with the response to interferon treatment

scientific article published on July 1996

Prognosis of Hepatocellular Carcinoma in Relation to Treatment Across BCLC Stages

scientific article published on 26 January 2011

Prognosis of hepatocellular carcinoma in relation to treatment: A multivariate analysis of 178 patients from a single European institution

scientific article published on 01 September 1998

Prognostic factors and prevention of radioembolization-induced liver disease

scientific article published on 15 February 2013

Prognostic model for early acute rejection after liver transplantation.

scientific article published in March 2001

Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer.

scientific article published on January 2004

Protection against liver damage by cardiotrophin-1: a hepatocyte survival factor up-regulated in the regenerating liver in rats

scientific article

Protection against woodchuck hepatitis virus (WHV) infection by gene gun coimmunization with WHV core and interleukin-12.

scientific article

Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III: Characterization of DDX3X as a target of S-adenosylmethionine

scientific article published on 16 January 2012

Pulsed electromagnetic fields reduce knee osteoarthritic lesion progression in the aged Dunkin Hartley guinea pig.

scientific article published on 17 March 2005

Radioembolization using 90Y-resin microspheres for patients with advanced hepatocellular carcinoma

scientific article published on 14 August 2006

Randomised trial of lymphoblastoid alpha-interferon in chronic hepatitis C. Effects on inflammation, fibrogenesis and viremia

scientific article published in March 1993

Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells.

scientific article published on 24 July 2007

Recombinant AAV Integration Is Not Associated With Hepatic Genotoxicity in Nonhuman Primates and Patients

scientific article published on 07 March 2016

Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.

scientific article published on 19 April 2006

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

scientific article published on 01 December 2000

Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12.

scientific article

Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system

scientific article

Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse

scientific article (publication date: 2012)

Replication of hepatitis C virus in peripheral blood mononuclear cells. Effect of alpha-interferon therapy

scientific article published on November 1992

Ribavirin in the treatment of chronic hepatitis C unresponsive to alfa interferon

scientific article published in November 1993

Risk factors for recurrence of hepatitis C after liver transplantation.

scientific article published on July 1998

Role of cardiotrophin-1 in obesity and insulin resistance

scientific article

S-adenosyl-L-methionine protects the liver against the cholestatic, cytotoxic, and vasoactive effects of leukotriene D4: a study with isolated and perfused rat liver

scientific article published on 01 August 1997

Self-inactivating helper virus for the production of high-capacity adenoviral vectors

scientific article published on 28 April 2011

Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

scientific article published on 09 September 2009

Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas

scientific article published on July 2005

Serum antibodies against porphyric hepatocytes in patients with porphyria cutanea tarda and liver disease

scientific article published on 01 June 1983

Serum ferritin assay and iron status in chronic renal failure and haemodialysis

scientific article published on 01 March 1975

Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes.

scientific article

Short-term intratumoral interleukin-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas.

scientific article published on 7 January 2014

Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

scientific article

Splenic embolization prior to myelosuppressive treatment in hepatocarcinoma and active chronic hepatitis

scientific article

Splicing regulator SLU7 is essential for maintaining liver homeostasis

scientific article published on 27 May 2014

Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic miR-17-92 cluster expression

scientific article published on 25 January 2016

Structure of the AvrBs3–DNA complex provides new insights into the initial thymine-recognition mechanism

scientific article

Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells.

scientific article published on 8 December 2010

Superoxide dismutase in patients with chronic hepatitis C virus infection

scientific article published on May 1998

Suppression of angiogenesis and tumor growth by adenoviral-mediated gene transfer of pigment epithelium-derived factor

scientific article published on July 2003

Surface chemistry and effects on bone regeneration of a novel biomimetic synthetic bone filler

scientific article published on 19 March 2015

Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice.

scientific article

Systemic and regional hemodynamics in patients with liver cirrhosis and ascites with and without functional renal failure.

scientific article

T-helper cell response to woodchuck hepatitis virus antigens after therapeutic vaccination of chronically-infected animals treated with lamivudine

scientific article published in July 2001

Taurocholate-stimulated leukotriene C4 biosynthesis and leukotriene C4-stimulated choleresis in isolated rat liver

scientific article published on 01 June 1995

The GCGGAA gene-regulatory motif of herpes simplex virus type-1 is also found in hepatitis C virus

scientific article published in February 1995

The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection

scientific article

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.

scientific article

The fusion protein of IFN-α and apolipoprotein A-I crosses the blood-brain barrier by a saturable transport mechanism

scientific article

The potential of gene therapy in the treatment of hepatocellular carcinoma

scientific article

The response of the hepatocyte to ischemia.

scientific article published on February 2007

The role of thrombopoietin in the thrombocytopenia of patients with liver cirrhosis.

scientific article

The woodchuck interferon-alpha system: Cloning, family description, and biologic activity

scientific article published in November 2002

Therapeutic vaccination of woodchucks against chronic woodchuck hepatitis virus infection.

scientific article published in October 1997

Thrombopenic purpura induced by a monoclonal antibody directed to a 35-kilodalton surface protein (p35) expressed on murine platelets and endothelial cells

scientific article

Tissue healing in implants immediately placed into postextraction sockets: a pilot study in a mini-pig model

scientific article

Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis

scientific article published on 01 September 2005

Toward the discovery of new biomarkers of hepatocellular carcinoma by proteomics.

scientific article published on March 2007

Tracing transgene expression in cancer gene therapy: a requirement for rational progress in the field.

scientific article published on January 2002

Transarterial therapies for hepatocellular carcinoma.

scientific article

Transcriptomic effects of Tet-on and mifepristone-inducible systems in mouse liver

scientific article

Transduction of hepatocellular carcinoma (HCC) using recombinant adeno-associated virus (rAAV): in vitro and in vivo effects of genotoxic agents

scientific article published on June 2000

Transformed but not normal hepatocytes express UCP2

scientific article published on 01 November 1998

Transforming growth factors beta 1 and alpha in chronic liver disease. Effects of interferon alfa therapy

scientific article published on 01 April 1991

Transjugular intrahepatic portal-systemic shunt in the treatment of refractory ascites: effect on clinical, renal, humoral, and hemodynamic parameters

scientific article published on 01 April 1995

Transmission of hepatitis C virus infection to tree shrews

scientific article published on May 1998

Transplantation of chondrocytes seeded on a hyaluronan derivative (hyaff-11) into cartilage defects in rabbits.

scientific article published in September 2001

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12.

scientific article published on 30 December 2008

Treatment of colorectal and hepatocellular carcinomas by adenoviral mediated gene transfer of endostatin and angiostatin-like molecule in mice.

scientific article published in April 2004

Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.

scientific article

Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ

scientific article published on 25 March 2010

Tubular sodium handling in cirrhotic patients with ascites as analysed by the renal lithium clearance method

scientific article published on 01 June 1990

Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C.

scientific article published in February 1996

Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis

scientific article published on 15 September 2010

Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis.

scientific article

Upregulation of indoleamine 2,3-dioxygenase in hepatitis C virus infection

scientific article published on 17 January 2007

Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease.

scientific article

Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.

scientific article

Usage of adenovirus expressing thymidine kinase mediated hepatocellular damage for enabling mouse liver repopulation with allogenic or xenogenic hepatocytes

scientific article

Vaccination against hepatitis C virus with dendritic cells transduced with an adenovirus encoding NS3 protein.

scientific article

Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus

scientific article published on December 2002

Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.

scientific article

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.

scientific article

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