List of works - Irene Luque

A New Physiological Role for the DNA Molecule as a Protector against Drying Stress in Desiccation-Tolerant Microorganisms.

scientific article published on 22 December 2016

Approaching the thermodynamic view of protein folding through the reproduction of Anfinsen's experiment by undergraduate physical biochemistry students

scientific article published on 4 January 2018

Balancing the effect of corona on therapeutic efficacy and macrophage uptake of lipid nanocapsules.

scientific article published on 13 May 2015

Crystal structure of the first WW domain of human YAP2 isoform

scientific article

Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand

scientific article

Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation

scientific article

From Binding-Induced Dynamic Effects in SH3 Structures to Evolutionary Conserved Sectors

scientific article published on 23 May 2016

Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.

scientific article published in February 2002

Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains

scientific article published on 11 May 2012

Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition.

scientific article published in March 2012

Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding

scientific article

Molecular Basis of Histone H3K4me3 Recognition by ING4

scientific article

Molecular Basis of Resistance to HIV-1 Protease Inhibition: A Plausible Hypothesis ⬇️

scientific article published on April 28, 1998

Post-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95

scientific article (publication date: 2014)

Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR

scientific article

Protein Folding Cooperativity and Thermodynamic Barriers of the Simplest β-Sheet Fold: A Survey of WW Domains

scientific article published on 30 July 2018

Role of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of Abl

scientific article

Structure of human TSG101 UEV domain

scientific article

Structure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repair

scientific article

Structure-based prediction of binding affinities and molecular design of peptide ligands.

scientific article

Structure-based thermodynamic analysis of HIV-1 protease inhibitors

scientific article published on 01 June 1997

Structure-based thermodynamic design of peptide ligands: Application to peptide inhibitors of the aspartic protease endothiapepsin ⬇️

scientific article published on January 1, 1998

Structure-based thermodynamic scale of alpha-helix propensities in amino acids

scientific article published on 01 October 1996

Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates

scientific article published on February 2017

The Strawberry Pathogenesis-related 10 (PR-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding to Metabolic Intermediates

scientific article

The application of thermodynamic methods in drug design

article by Adrian Velazquez-campoy et al published December 2001 in Thermochimica Acta

The linkage between protein folding and functional cooperativity: two sides of the same coin?

scientific article

The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)

scientific article published on 17 January 2019

The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein

scientific article

Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition: Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant†

article

Thermodynamic characterization of the folding equilibrium of the human Nedd4-WW4 domain: at the frontiers of cooperative folding.

scientific article published in September 2009

Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design

scientific article

Thermodynamic impact of embedded water molecules in the unfolding of human CD2BP2-GYF domain

scientific article

Two-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-cap

scientific article published on 19 August 2013

Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding

scientific article published on 09 April 2019

WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands.

scientific article published on 21 January 2015

List of works by Irene Luque

A New Physiological Role for the DNA Molecule as a Protector against Drying Stress in Desiccation-Tolerant Microorganisms.

Approaching the thermodynamic view of protein folding through the reproduction of Anfinsen's experiment by undergraduate physical biochemistry students

Balancing the effect of corona on therapeutic efficacy and macrophage uptake of lipid nanocapsules.

Crystal structure of the first WW domain of human YAP2 isoform

Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand

Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation

From Binding-Induced Dynamic Effects in SH3 Structures to Evolutionary Conserved Sectors

Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.

Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains

Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition.

Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding

Molecular Basis of Histone H3K4me3 Recognition by ING4

Molecular Basis of Resistance to HIV-1 Protease Inhibition: A Plausible Hypothesis ⬇️

Post-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95

Proliferating cell nuclear antigen (PCNA) interactions in solution studied by NMR

Protein Folding Cooperativity and Thermodynamic Barriers of the Simplest β-Sheet Fold: A Survey of WW Domains

Role of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of Abl

Structure of human TSG101 UEV domain

Structure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repair

Structure-based prediction of binding affinities and molecular design of peptide ligands.

Structure-based thermodynamic analysis of HIV-1 protease inhibitors

Structure-based thermodynamic design of peptide ligands: Application to peptide inhibitors of the aspartic protease endothiapepsin ⬇️

Structure-based thermodynamic scale of alpha-helix propensities in amino acids

Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates

The Strawberry Pathogenesis-related 10 (PR-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding to Metabolic Intermediates

The application of thermodynamic methods in drug design

The linkage between protein folding and functional cooperativity: two sides of the same coin?

The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)

The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein

Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition: Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant†

Thermodynamic characterization of the folding equilibrium of the human Nedd4-WW4 domain: at the frontiers of cooperative folding.

Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design

Thermodynamic impact of embedded water molecules in the unfolding of human CD2BP2-GYF domain

Two-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-cap

Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding

WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands.