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List of works by Massimo Negrini

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

scientific article

A microRNA expression signature of human solid tumors defines cancer gene targets

scientific article

A microRNA signature of hypoxia

scientific article

A new chromosomal breakpoint in Ph positive, bcr negative chronic myelogenous leukemia. Report of a case

scientific article published on 01 July 1992

A novel t(9;11)(p22;q23) with ALL-1 gene rearrangement associated with progression of a myeloproliferative disorder to acute myeloid leukemia ⬇️

scientific article published on August 1, 1995

A transcriptome-wide approach reveals the key contribution of NFI-A in promoting erythroid differentiation of human CD34(+) progenitors and CML cells.

scientific article published on 29 April 2010

Absolute quantification of cell-free microRNAs in cancer patients

scientific article

Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer

article

Altered miRNA expression in T regulatory cells in course of multiple sclerosis

scientific article

Anti-tumor activity of a miR-199-dependent oncolytic adenovirus

scientific article (publication date: 2013)

Anticancer activity of an adenoviral vector expressing short hairpin RNA against BK virus T-ag.

scientific article published on 12 January 2007

Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia

scientific article published on 10 April 2015

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia

scientific article published on January 2011

Associations of risk factors obesity and occupational airborne exposures with CDKN2A/p16 aberrant DNA methylation in esophageal cancer patients

scientific article published on 29 April 2010

BCR/ABL1-positive acute lymphoblastic leukemia relapsing as BCR/ABL1-negative acute lymphoblastic leukemia.

scientific article

BK virus, JC virus and Simian Virus 40 infection in humans, and association with human tumors.

scientific article

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

scientific article published on 24 June 2013

Cellular and Kaposi's sarcoma-associated herpes virus microRNAs in sepsis and surgical trauma

scientific article

Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia with "normal" FISH: correlations with clinicobiologic parameters.

scientific article published on 13 January 2012

Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia: Clinical and biologic correlations

scientific article published on 10 September 2015

Chromosome aberrations in atypical chronic lymphocytic leukemia: a cytogenetic and interphase cytogenetic study ⬇️

scientific article published on 01 November 1997

Chronic lymphocytic leukemia with 6q- shows distinct hematological features and intermediate prognosis

scientific article published on 01 March 2004

Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC.

scientific article published on 28 October 2015

Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features.

scientific article

Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors

scientific article published on October 2002

Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts

scientific article published on 01 December 2004

Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma

scientific article

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

scientific article published on October 2012

Diagnostic and prognostic microRNAs in the serum of breast cancer patients measured by droplet digital PCR.

scientific article published on 6 June 2015

Dissecting chronic lymphocytic leukemia with 13q- using microRNA expression profile: Editorial for the paper "MiRNA expression profile of chronic lymphocytic leukemia patients with 13q deletion".

scientific article published on 27 May 2016

Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25

scientific article published on 13 December 2012

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

scientific article

Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival

scientific article

Extensive modulation of a set of microRNAs in primary glioblastoma

scientific article

First report of circulating microRNAs in tumour necrosis factor receptor-associated periodic syndrome (TRAPS). ⬇️

scientific article

Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer.

scientific article

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

scientific article

Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic keratinocytes

scientific article published on April 2015

Genome wide identification of recessive cancer genes by combinatorial mutation analysis

scientific article

HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts.

scientific article published on 13 September 2013

High-sensitivity assay for monitoring ESR1 mutations in circulating cell-free DNA of breast cancer patients receiving endocrine therapy.

scientific article

Human homeobox gene HOXC13 is the partner of NUP98 in adult acute myeloid leukemia with t(11;12)(p15;q13)

scientific article published on 01 April 2003

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

scientific article

In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.

scientific article published on 18 April 2012

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

scientific article

Interspecies Gene Name Extrapolation--A New Approach.

scientific article published on 25 September 2015

Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.

scientific article

Karyotype-specific microRNA signature in chronic lymphocytic leukemia

scientific article published on 28 August 2009

Loss of methylation at chromosome 11p15.5 is common in human adult tumors

scientific article published on 01 April 2002

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

scientific article published on 01 February 2000

MINT31 methylation in gastric noninvasive neoplasia: potential role in the secondary prevention of gastric cancer.

scientific article published in September 2012

Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16→q21 ⬇️

scientific article published on 01 January 1997

Mechanisms causing imprinting defects in familial Beckwith–Wiedemann syndrome with Wilms' tumour

scientific article published on 11 December 2006

Mesenchymal Progenitors Aging Highlights a miR-196 Switch Targeting HOXB7 as Master Regulator of Proliferation and Osteogenesis

scientific article published on 01 March 2015

Metformin prevents liver tumourigenesis by attenuating fibrosis in a transgenic mouse model of hepatocellular carcinoma

scientific article published on 13 August 2019

MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells

scientific article

MiR-15a and miR-16-1 cluster functions in human leukemia

scientific article

MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells

scientific article

MiR-30e-3p influences tumor phenotype through MDM2/TP53 axis and predicts sorafenib resistance in hepatocellular carcinoma

scientific article published on 03 February 2020

MicroRNA deregulation in human thyroid papillary carcinomas.

scientific article published on June 2006

MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation.

scientific article

MicroRNA expression profiling identifies miR-31-5p/3p as associated with time to progression in wild-type RAS metastatic colorectal cancer treated with cetuximab.

scientific article published on 20 October 2015

MicroRNA fingerprints identify miR-150 as a plasma prognostic marker in patients with sepsis

scientific article published in 2009

MicroRNA gene expression deregulation in human breast cancer

scientific article (publication date: 15 August 2005)

MicroRNA involvement in hepatocellular carcinoma

scientific article published on December 2008

MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin

scientific article

MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy

scientific article

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

scientific article

MicroRNA profiling reveals that miR-21, miR486 and miR-214 are upregulated and involved in cell survival in Sézary syndrome ⬇️

scientific article published on April 28, 2011

MicroRNA response to environmental mutagens in liver.

scientific article published on 14 April 2011

MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality

scientific journal article

MicroRNA-mediated regulation of pancreatic cancer cell proliferation.

scientific article published on May 2010

MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches.

scientific article

MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia.

scientific article

Micromarkers 2.0: an update on the role of microRNAs in cancer diagnosis and prognosis.

scientific article published on 04 September 2015

Micromarkers: miRNAs in cancer diagnosis and prognosis.

scientific article

Modern treatment in chronic lymphocytic leukemia: impact on survival and efficacy in high-risk subgroups

scientific article

Modulation of mismatch repair and genomic stability by miR-155

scientific article

Molecular Cloning and Characterization ofLOH11CR2A,a New Gene within a Refined Minimal Region of LOH at 11q23 ⬇️

scientific article published on December 1, 1997

Molecular Cloning and Characterization ofZNF202:A New Gene at 11q23.3 Encoding Testis-Specific Zinc Finger Proteins ⬇️

scientific article published on September 15, 1998

Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer

scientific article

Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4

scientific article

Non-coding RNAs in the reprogramming of glucose metabolism in cancer.

scientific article published on 20 January 2018

Oncogenic transformation by BK virus and association with human tumors.

scientific article

OncomiR detection in circulating body fluids: a PDMS microdevice perspective

scientific article published on October 2014

Over-expression of the miR-483-3p overcomes the miR-145/TP53 pro-apoptotic loop in hepatocellular carcinoma.

scientific article

Pluripotent stem cell miRNAs and metastasis in invasive breast cancer

scientific article

Prediction of response to anti-EGFR antibody-based therapies by multigene sequencing in colorectal cancer patients.

scientific article

Prevalence of the archetypal regulatory region and sequence polymorphisms in nonpassaged BK virus variants ⬇️

scientific article published on September 1, 1991

Proliferation centers in chronic lymphocytic leukemia: correlation with cytogenetic and clinicobiological features in consecutive patients analyzed on tissue microarrays.

scientific article published on 23 September 2011

Quantification of circulating miRNAs by droplet digital PCR: comparison of EvaGreen- and TaqMan-based chemistries.

scientific article published on December 2014

Refinement of the LOH region 1 at 11q23.1 deleted in human breast carcinomas and sublocalization of 11 expressed sequence tags within the refined region

scientific article published on 01 February 1999

Reprogramming of miRNA networks in cancer and leukemia

scientific article

Role of microRNAs in hepatocellular carcinoma: a clinical perspective

scientific article

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells

scientific article published on 18 February 2020

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

scientific article

Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.

scientific article published on 3 October 2012

TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia

scientific article

The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene

scientific article

The methylator phenotype in microsatellite stable colorectal cancers is characterized by a distinct gene expression profile

article

Transcriptional map of 170-kb region at chromosome 11p15.5: Identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples ⬇️

scientific article published on March 31, 1998

Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas

scientific article (publication date: September 2007)

Unraveling the role of microRNA/isomiR network in multiple primary melanoma pathogenesis

scientific article published on 12 May 2021

Use of herpes simplex virus type 1-based amplicon vector for delivery of small interfering RNA.

scientific article published on 19 October 2006

miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression

scientific article

miR-126&126* restored expressions play a tumor suppressor role by directly regulating ADAM9 and MMP7 in melanoma.

scientific article

miR-15 and miR-16 induce apoptosis by targeting BCL2

scientific article

miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model.

scientific article

miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance.

scientific article

miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs

scientific article

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

scientific article published on April 2012

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

scientific article published on 05 April 2016

microRNA Involvement in Hepatocellular Carcinoma ⬇️

scientific article published on July 1, 2011

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival

scientific article published on 14 April 2010

microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer ⬇️

scientific article published on May 30, 2011

microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters

scientific article published on 10 June 2014

p53/mdm2 feedback loop sustains miR-221 expression and dictates the response to anticancer treatments in hepatocellular carcinoma

scientific article published on 9 December 2013

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