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List of works by Filomena De Luca

Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam

scientific article published on 20 June 2018

Crystal Structure of the Narrow-Spectrum OXA-46 Class D  -Lactamase: Relationship between Active-Site Lysine Carbamylation and Inhibition by Polycarboxylates

scientific article

Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum β-Lactamase and its Complex with Moxalactam and Imipenem

scientific article

Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases

scientific article

Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

scientific article published on 16 December 2019

Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D  -lactamase OXA-10 by rational protein design

scientific article

Molecular basis of selective inhibition and slow reversibility of avibactam against class D carbapenemases: a structure-guided study of OXA-24 and OXA-48

scientific article

SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model

scientific article published on 30 November 2018

Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC  -Lactamases

scientific article

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa

scientific article published on 21 February 2020

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