List of works - Rosaria Luciani

2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives

scientific article

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes

scientific article published on 30 January 2014

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells

scientific article

Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case.

scientific article published on 12 July 2016

Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth

scientific article published on 26 September 2019

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

scientific article

Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening

scientific article

Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase

scientific article

Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors

scientific article published on October 2010

Optimization of peptides that target human thymidylate synthase to inhibit ovarian cancer cell growth

scientific article published on 12 February 2014

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

scientific article

Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

scientific article

Structure-based selectivity optimization of piperidine-pteridine derivatives as potent Leishmania pteridine reductase inhibitors

scientific article

The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism

scientific article

Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase

scientific article

X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors

scientific article

List of works by Rosaria Luciani

2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells

Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case.

Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening

Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase

Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors

Optimization of peptides that target human thymidylate synthase to inhibit ovarian cancer cell growth

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

Structure-based selectivity optimization of piperidine-pteridine derivatives as potent Leishmania pteridine reductase inhibitors

The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism

Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase

X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors