List of works - Rosaria Luciani

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

scientific article

Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

scientific article

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase

scientific article

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells

scientific article

Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors

scientific article published on October 2010

Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase

scientific article

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

scientific article

The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism

scientific article

Structure-based selectivity optimization of piperidine-pteridine derivatives as potent Leishmania pteridine reductase inhibitors

scientific article

Optimization of peptides that target human thymidylate synthase to inhibit ovarian cancer cell growth

scientific article published on 12 February 2014

X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors

scientific article

Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening

scientific article

Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case.

scientific article published on 12 July 2016

2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives

scientific article

2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes

scientific article published on 30 January 2014

Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth

scientific article published on 26 September 2019

List of works by Rosaria Luciani

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells

Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors

Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs

The structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism

Structure-based selectivity optimization of piperidine-pteridine derivatives as potent Leishmania pteridine reductase inhibitors

Optimization of peptides that target human thymidylate synthase to inhibit ovarian cancer cell growth

X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors

Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening

Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case.

2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives

2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes

Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth